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FACT: DENTAL CARIES IS THE MOST COMMON CHRONIC DISEASE ON THE PLANET1

HOW DO YOU CARE FOR YOUR AT-RISK PATIENTS?

PRESCRIBE OUR MOST ADVANCED FORMULA FOR UNSURPASSED REMINERALIZATION*2

1.1% Sodium Fluoride Anti-caries Toothpaste (Rx Only)

IMPROVED

PreviDent® 5000 BOOSTER PLUS

Contains tricalcium

phosphate

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150

100

50

-50

0

200

250

Fluoride-Free MI Paste Plus™ ClinPro™ 5000 ImprovedPreviDent® 5000

Booster PLUS

10 days

20 days

% C

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Sur

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To Order: 1-800-372-4346

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Remineralization after 10 and 20 days2

PLUS FluoriGard™ † TechnologyAn optimized fluoride delivery system that produces a temporary shift in the pH, resulting in an 86% improvement in fluoride uptake.‡3

PLUS 20 years of PreviDent® Leadership in Rx FluoridesAssess often to identify those at risk of caries and prescribe Colgate® PreviDent® 5000 Booster PLUS.

Colgate® PreviDent® 5000 Booster Plus (Rx Only) 1.1 Sodium Fluoride Prescription-strength Toothpaste

3.4 fl. oz. (100 mL) Spearmint .........................(543-0080)

PLUS Unsurpassed Remineralization

UNSURPASSED REMINERALIZATION AFTER 20 DAYS*

2

BETTER REMINERALIZATION AFTER 10 DAYS§2

Polished enamel specimens were acid challenged to create lesions, then evaluated for baseline surface microhardness. Specimens were then exposed to an in vitro pH-cycling model consisting of periods of acid challenge (favoring demineralization, 4-hr daily), fluoride exposure (via toothpaste slurry exposure; 1 minute, 4 times daily), and artificial saliva (favoring remineralization; 20 hours each day) for 20 days. Surface microhardness measurements were repeated at day 10 and day 20 for comparison to baseline, and reported as percent change in surface microhardness after 10 or 20 days of pH cycling.

Important Safety Information: PreviDent® 5000 Booster Plus (1.1% Sodium Fluoride) is a dental caries preventative toothpaste for adults and pediatric patients 6 years of age and older. The product is for once daily, topical use. It is not to be swallowed. Allergic reactions and idiosyncrasies have been rarely reported. See other side for brief summary of risk information.

References: 1. Beaglehole R, Benzian H, Crail J, Mackay J. “The Oral Health Atlas: Mapping a Neglected Global Health Issue. Geneva & Brighton: FDI World Dental Education Ltd & Myriad Editions; 2009.” 2. Data on file; Colgate-Palmolive, 2012. In vitro pH cycling model after 10 and 20 days. 3. Data on file; Colgate-Palmolive, 2012. In vitro standard method for enamel fluoride uptake.

* Statistically better when compared to MI Paste Plus™ topical creme and PreviDent® 5000 Booster.

†Optimized fluoride delivery system.‡Comparison vs PreviDent® 5000 Booster. § Statistically better when compared to ClinPro™ 5000, MI Paste Plus™ topical creme, and PreviDent® 5000 Booster.

www.colgateprofessional.com

Questions? Comments? Please call 1-800-962-2345 © 2012 Colgate Oral Pharmaceuticals, a subsidiary of Colgate-Palmolive Company, New York, NY 10022, USA

INTRODUCING

PreviDent® 5000 BOOSTER PLUS

3.4 fl. oz. (100 mL) Fruitastic™..........................(543-0079)