How do cells multiply?

Cell/Developmental Biology Group

The Cyclers

Gre

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Claudette

Davis

Vet

Doz

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StanleyLo

KatieNemeth

SteveChordas, III

Peter

Cavnar

Background of the Class

• Course: Introduction to Biology (Majors)• Class Size: 55+ students• Module: Cell Biology, two-week (6 lectures)

teachable unit on cell cycle• First class of the unit• What do students know already?

Nucleotides, DNA, chromosomes, and organelles• Students will learn about the cell cycle.

(for SI participants only)

The Cell Cycle

Who cares?

Cancer: 23% of all deaths in US in 2007 resulted from cancer

How does cell division relate to human health?

Down Syndrome:1 in 800 babies born in US

What will we learn today?

• We will be able to explain why each of the phases of the cell cycle occur in the order that they do

How will we learn how cells divide?

Overview:

In small groups (two groups per table) we will:

• Generate a common list of events

• Determine the order in which the events occur

• Brainstorm to determine what the most basic events the cell must undergo to achieve division

Brainstorm Question…

Come up with a list of actions or events that an animal cell must

undergo to achieve division.

2 minutes

Work in your groups to arrange the notes in the order that would make the cell divide…

(3 min)

cell cycle

cell cycle

cell cycle

Where do we go from here?

Today• We will be able to sequence the events of the cell

cycle and explain why each of the phases occur in the order that they do

Rest of Teachable Unit• To know what checkpoints and their functions are • To understand the functions of cyclins and CDKs

(e.g. concentrations at different stages of cell cycle, different specificities, activities regulated by other proteins)

• Mitosis: what is it and what is the outcome?• What actions occur to move the chromosomes and

divide the two cells?• To understand diseases related to the cell cycle

relate to diseases