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New Technology from Institute of Technology Tallaght

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Advantages

Industrial Applications

Commercial OpportunityDIT Hothouse is currently seeking a commercial partner to take this technology to market. Ireland's dairy industry has ambitious expansion plans. In July 2000, Food Harvest 2020 (an Industry & dept of Agriculture group) set a high profile target of 50% milk output expansion by 2020. Irish dairy famers have bought into this plan and have been investing in expansing their facilities and lands. BovAlert can help to ensure this target is met through the detection of liver fluke in cows, reducing time and money spent on treatment and ensuring milk production is at its optimum. Hothouse offers excellent commercial terms to licensees on technologies developed through ITTD research.

Product Offering

BovAlertPriority Animal Health Testing

Industrial Technology

Researchers from the MiCRA centre in Institute of Technology Tallaght have developed a novel device for on-farm liver fluke diagnosis in dairy animals.

BovAlert is an electrochemical diagnostic device which tests the milk of animal herds for liver fluke, providing quick and easy information regarding disease status. The liver-fluke test produces differential information regarding vaccinated versus fluke-infected animal test results.

Enables rapid and quantitative measurement of anti-Fasciola antibodies in milk and sera.

Facilitates out of laboratory testing with results in under ten minutes.

Requires minimal end user input (sample in, result out).

Capable of multiplexing and being expanded to detect a wide variety of heard diseases.

Single use disposable and very cost effective.

BovAlert is based on ITT Dublin’s membrane touch and electrochemical ELISA technologies. The platform can be easily reconfigured to detect analytes of interest in the following Industries:

• Food and beverage manufacture• Environmental assessment• In-vitro diagnostics• Pharmaceutical process control• Pathogen detection

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Stage of DevelopmentPrototyping and validation of both the electrochemical chip and the display module. The technology is patent pending.

HothouseDIT Aungier Street, Dublin 2 T: +353 1 402 7179E: hothouse@dit.ieW: www.dit.ie/hothouse

DIT Hothouse is the award winning Innovation and Technology Transfer Centre based in Dublin Institute of Technology. Hothouse leads the consortium responsible for commercialising research from DIT, IT Tallaght, IT Blanchardstown, IADT and National College of Ireland.

Hothouse draws in entrepreneurial and academic talent, ignites creativity and provides a dynamic environment to fast-track businesses and technologies to commercial success.

HOTHOUSE INFO SHEETS_TTL Multichannel 23/11/2012 11:51 Page 2

The technology consists of:

1. A small, lightweight touch pump fluid injector andreagent cartridge, that is capable of storing and pumping small volumes of liquid form from one location on the cartridge to another.

Technology Description

If you would like to learn more about this technology or discuss commercial opportunities, please contact: Kieran O'Connell, Licensing Executive, DIT Hothouse

on 01 402 3111 or email kieran.oconnell@dit.ie

Next Steps

BovAlert Priority Animal Health Testing

New Technology from Institute of Technology Tallaght

Industrial Technology

Right: Laboratory prototype – the Membrane Touch ELISA (Enzyme-linked immuno-sorbent assay)

Project Team and CollaboratorsPrimary Investigator - Prof. Eithne Dempsey Project Team - Prof. Grace Mulcahy, Dr. Brian Seddon, Dr Baljit Singh, Dr. James Hayes, Dr Simon Egan. Dr. Mary Sekiya.

2. Custom designed reader software to enable datadiscrimination and verification of vaccinated vs. liverfluke infected milk samples.

Intellectual PropertyTo protect the intellectual property associated with this technology, a patent has been filed.