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HOMEOSTASIS The term homeostasis refers to the body’s attempt to adjust to a fluctuating external environment… » Homeostasis = the process by which a constant internal environment is maintained despite changes in the external environment In Greek, ‘homois’ means “similar” and stasis’ means “standing still”! Homeostasis is also referred to as DYNAMIC EQUILIBRIUM ! Thursday, July 14, 2011

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Page 1: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• The term homeostasis refers to the body’s

attempt to adjust to a fluctuating external environment…

» Homeostasis = the process by which a constant internal environment is maintained despite changes in the external environment

In Greek, ‘homois’ means “similar” and ‘stasis’ means “standing still”!

Homeostasis is also referred to as DYNAMIC EQUILIBRIUM!

Thursday, July 14, 2011

Page 2: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• Our body has several preferred homeostatic

values for life:Body Temperature = 37oC

Blood Sugar level = 0.1% glucose

Blood pH Level = 7.35

Blood pressure = 120/80 mmHg

In order to maintain these values, the body makes use of various control systems which must monitor, coordinate and regulate these

values!

Thursday, July 14, 2011

Page 3: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• Different organs are involved with the

regulation of different systems:

Kidneys maintain H2O

balance!

Hypothalamus regulates temperature and changes osmotic pressure!Pancreas regulates

blood sugar!

Blood distributes heat throughout the body!

Skeletal muscle contracts and releases heat!

Thursday, July 14, 2011

Page 4: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• A homeostatic control system must have 3

functional components!

» 1. MONITOR – special sensors (located within organs) that send a signal to the coordinating center once an organ begins to operate outside its normal limits.

» 2. COORDINATING CENTER – a processing center that will process the information from the monitor and relay the appropriate response to the regulator.

» 3. REGULATOR – will take an action in order to help restore values to normal.

Thursday, July 14, 2011

Page 5: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASISLet’s look at the example of heating a house!

Which component is the MONITOR, COORDINATING CENTER and REGULATOR?

COORDINATING CENTER!

MONITOR!

REGULATOR!

Thursday, July 14, 2011

Page 6: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• In the example of heating your house, the furnace

(regulator) can be turned on if the house gets too cold and turned off if the house gets too warm

» This is referred to as a NEGATIVE FEEDBACK SYSTEM!!!!!!

Negative Feedback = a process by which a change in the variable being monitored triggers the control mechanism to counteract any further change in the same direction.

Thursday, July 14, 2011

Page 7: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• Most homeostatic mechanisms in animals (humans

too) operate on the principle of negative feedback!

Common examples include BODY TEMPERATURE regulation and BLOOD SUGAR levels!

Thursday, July 14, 2011

Page 8: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

Thursday, July 14, 2011

Page 9: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

Thursday, July 14, 2011

Page 10: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• While negative feedback loops are far more

prevalent in animals, the opposite is also possible, a POSITIVE FEEDBACK LOOP.

» POSITIVE FEEDBACK = a process by which a small effect is amplified!

Whereas negative feedback loops are designed to resist change, positive feedback loops REINFORCE the

change!!!!

Thursday, July 14, 2011

Page 11: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• A good example of positive feedback in

humans is the birthing process!!!!

Thursday, July 14, 2011

Page 12: HOMEOSTASIS - lorenowicz.weebly.com · HOMEOSTASIS • Different organs are involved with the regulation of different systems: H 2 O ! Hypothalamus regulates temperature and changes

HOMEOSTASIS• In the case of positive feedback, once the

event in question is accomplished, the feedback system stops!

– Ie: once a baby is born, uterine contractions cease as does the release of oxytocin!

Thursday, July 14, 2011