histology for pathology hepatobiliary system (accessory digestive organs)
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Histology for Pathology Hepatobiliary System (Accessory Digestive Organs). Silver Daniel, MD Assistant Professor Theresa Kristopaitis, MD Associate Professor Director of Mechanisms of Human Disease Kelli A. Hutchens, MD, FCAP Assistant Professor - PowerPoint PPT PresentationTRANSCRIPT
Histology for PathologyHepatobiliary System
(Accessory Digestive Organs)
Silver Daniel, MDAssistant Professor
Theresa Kristopaitis, MDAssociate Professor
Director of Mechanisms of Human Disease
Kelli A. Hutchens, MD, FCAPAssistant Professor
Assistant Director of Mechanisms of Human Disease
Loyola Stritch School of Medicine
Hepatobiliary Histology
• On a low power H&E stained section outline a liver lobule.• Explain the rationale of dividing the hepatic acinus into three zones. • Identify the components of the portal triad/tract: portal vein,
hepatic artery, bile duct.• Identify hepatic sinusoids and describe the endothelium that lines
the sinusoids.• Define “Kupffer cells” and their function.• List the structures that form the space of Disse.• Describe the path of blood flow as it is filtered through the liver.• Describe the location of bile canaliculi and their function. • Describe the path of bile flow from the liver to the gallbladder.• Identify the three layers of the gallbladder: mucosa, muscularis and
serosa/adventitia.
Image courtesy of Robbins and Cotran Pathologic Basis of Disease, 7th edition
Image courtesy of www.apsu.edu
Image courtesy of Nature Reviews Immunology , March 2006
Biliary TractFlow of bile from liver
Image courtesy of Robbins and Cotran Pathologic Basis of Disease, 7th edition