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Part of a pure process™
Meeting today’s highest quality standards
Histology and Cytology Reagents
Bright solutions for Histology and Cytology
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Mallinckrodt Baker’s chemical expertise and over 30 years of experience are the foundation of our
J.T. Baker products for Histology and Cytology. Within our Histopathology product line we offer
a comprehensive range of fi xatives, reagents, solvents, stains, and environmentally friendly
clearing agent and auxiliary products especially formulated and purifi ed for use in histology
and cytology applications.
In Histopathology we offer:
• Products for a Xylene free laboratory
• Fixatives
• Staining solutions
• Alcohols and solvents
� Our Histopathology products are produced
using state-of-the-art production and packaging
techniques in modern certified manufacturing
facilities.
QualityOur products are designed and manufactured
according to the following Quality systems:
• NEN-EN-ISO 9001
• NEN-EN-ISO 14001
• IVD Directive 98/79/EC; all our products that are
subject to the Directive are registered and CE
marked
• International Responsible Care; our contribute to
environmental friendly and effi cient manufacturing
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▲ Mounting slides with Ultrakitt
UltraClear
UltraClear is an iso-paraffi n based clearing reagent.
UltraClear may be used as a Xylene replacement
during tissue embedding, de-paraffi nation and staining
processes. UltraClear is less toxic, less-carcinogenic,
less-fl ammable, odorless and easy to adapt with
existing working protocols.
UltraKitt
UltraKitt is a mounting medium that is miscible with
UltraClear, Xylene, Toluene and Iso-propylalcohol (IPA).
UltraKitt is unique, with a granted and fi led patent for
Europe and the USA. UltraKitt is safe as it does not
contain dangerous aromatic solvents like Xylene or
Toluene.
UltraClear, UltraKitt, Paraffi n Cleaner:The complete solution for a Xylene free laboratory
Product Product Number Packaging Content
UltraClear 3905 Tin can 2.5L, 5L, 10L
Steel drum 200L
UltraKitt 3921 Glass bottle 500 ml, 6 x 100 ml
Paraffi n Cleaner 3451 HDPE* Spray bottle 12 x 125 ml
Ordering information UltraClear, UltraKitt, Paraffin Cleaner
Suitable Convenient Consistent Complete
Suitable
• Clearing agent between alcohol and Paraffi n
• Easy to adapt
• Advised working procedures available
Convenient
• More human- and environ mentally friendly
• Odorless
• Less fl ammable
Consistent
• No lot to lot variation
• Superior immuno-staining results
Complete
• UltraClear, UltraKitt and Paraffi n Cleaner are an
optimized set of products to completely eliminate
Xylene from the Histopathology laboratory
Paraffin Cleaner
Paraffi n Cleaner is a specially designed cleaner for
laboratory equipment such as processors and
microtomes. Paraffi n Cleaner contains mineral oils in
an alcoholic medium.
*High Density Polyethylene
Suitable Convenient Consistent Complete
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▲ Easy pouring formaldehyde solution
Fixatives, a suitable solution for each application
Formaldehyde solutions
Effective and reproducible fi xation requires buffered
formaldehyde. Non-buffered formaldehyde solutions
are acidic and therefore have an inconsistent pH.
When formaldehyde is acidic, the formation of
formalin-heme pigments may occur.
To obtain optimized fi xation, the buffer concentration
is critical. The 40mM phosphate buffer used in the
J.T.Baker Formaldehyde solutions has proven to be the
best choice as it gives the best overall performance
and the optimum result in immunostaining.
We offer formaldehyde fi xatives as ready to use or
concentrated solutions in various pack-sizes and
packaging materials such as bag-in-box systems and
HDPE containers (for dust free area’s).
Formalin Neutraliser
Formalin Neutraliser facilitates the safe disposal of
used or spilled formalin.
Bouin’s Fixative
Bouin’s Fixative is a picric acid based fi xative used in a
variety of fi xation procedures. It is a popular fi xative
for embryonic studies and skin, due to its excellent
preservation of nuclei and chromosomes.
Cervix Spray Fixative
Cervix Spray Fixative is a non-toxic solution used to fi x
prepared cell smears in such a way that staining with
Papanicolaou gives optimized coloration of all cell
structures.
Suitable Convenient Consistent Complete
Suitable
• Ready to use solutions
• Optimized buffer concentration
• Low concentrate phosphate
Convenient
• Easy to carry bag in box or HDPE can
• Certifi cate of Analysis available at
www.mallbaker.com
• Taps available to easily pour the product
Consistent
• No lot to lot variation
• Optimized results in immunochemistry staining
Complete
• Ready to use and concentrated solutions
• Wide range of packaging options
Product Product Number Packaging Content
Formaldehyde Solution 4% w/v (10% v/v) 3933 HDPE 1L, 200L
Jerrycan 10L, 20L
Cubitainer 5L, 10L, 20L
Formaldehyde Solution 19% w/v 3858 Jerrycan 20L
Formaldehyde Solution 38% w/v 3859 Jerrycan 5L, 10L
Formaldehyde Neutraliser 3934 PP drum 5 kg
Bouin’s Fixative 3880 HDPE 1L, 60L
Cervix Spray Fixative 3869 HDPE Spray bottle 12 x 125 ml
Ordering information Fixatives
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▲ Handling staining solution
May-Grünwald, Giemsa, Wright and Leishman
These stains are used for tissue sections, cytology
smears, blood smears and bone marrow. Our production
methods and formulations are modifi ed to the highest
standards, resulting in optimized color intensity.
Hemacolour and Sørensen buffer
Hemacolour is a fast, effi cient and convenient staining
method for blood smears replacing the traditional May
Grünwald and Giemsa method. The procedure takes
less than 1 minute and requires only 1 solution. To
ensure the consistency it is advised to use Sørensen
buffer instead of water.
Hematoxylin and Eosin (H&E)
Our Hematoxylin is available according to Mayer and
Gill II/Harris. Modern technology allows a time and
temperature controlled manufacturing process. This
process guarantees a fi nal product with long stability
together with a consistent and bright staining of the
nucleus. J.T.Baker Eosin Y stains are offered as alcoholic
Stains, bright and reliable solutions
Product Product Number Packaging Content
Eosine Y, 0.2% alcoholic 3871 Glass bottle 1L, 2.5L
Eosine Y, 0.2% aqueous 3874 Glass bottle 1L, 2.5L
Giemsa 3856 Glass bottle 500 ml, 1L, 2.5L
Hemacolour 3719 Glass bottle 300 ml, 1L
Hematoxylin, Harris, Gill II 3873 Glass bottle 1L, 2.5L
Hematoxylin, Mayer 3870 Glass bottle 1L, 2.5L
Leishman 3879 Glass bottle 1L, 2.5L
May-Grünwald 3855 Glass bottle 500 ml, 1L, 2.5L
Papanicolaou 2A OG6 3864 Glass bottle 1L, 2.5L
Papanicolaou 2B Orange II 3865 Glass bottle 1L, 2.5L
Papanicolaou 3B EA 50 3866 Glass bottle 1L, 2.5L
Scotch Solution 3872 Cubitainer 5L
Sørenson Buffer 20x concentrated 3716 HDPE bottles 10 x 100 ml
Ordering information Stains
Suitable Convenient Consistent Complete
Suitable
• Method sheets available at www.mallbaker.com
• Applicable to all known staining procedures
Convenient
• Ready-to-use solutions
• Color tones are easy adjusted
Consistent
• No lot to lot variation
• Free from crystals
Complete
• Available in a variety of pack-sizes
• All routine stains available
or aqueous solutions. Our Eosin Y counter stains are
optimized in combination with our hematoxylin stains. In
addition we also offer a Scotch solution, which enables a
stable and optimised bluing of the cell nucleus.
Papanicolaou stains
Experienced laboratory technicians claimed that
results obtained with the J.T.Baker PAP stains are of
superb colour intensity. All of our PAP staining
solutions are purifi ed and free from contamination. We
offer Papanicolaou 1 (Hematoxylin according to GilI II/
Harris), Papanicolaou 2A (Orange G6), Papanicolaou
2B (Orange II) and Papanicolaou 3B (EA 50).
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Alcohols and Solvents, UltraPar, Rapid Decalcifi er, Immuno PBS
Alcohols and Solvents
We offer Xylene and Toluene in a Histograde quality.
Alcohols are available in variety of packsizes and
specifi cations, in convenient and easy-to-carry HDPE
cans.
UltraPar
UltraPar is a special particle-free paraffi n intended for use
in tissue embedding and sectioning in histology. When
melted UltraPar is a clear and bright solution, the
solubility of UltraPar in UltraClear is better than other
Paraffi ns. UltraPar does not crack or shrink during cooling.
Rapid Decalcifier
Rapid Decalcifi er is intended to be used for fast and
complete decalcifying of bone-marrow and bone
containing tissue sections. The speed of processing can
be controlled by dilution with water. J.T.Baker Rapid
Decalcifi er also decalcifi es hip-bones within 24 hours.
It gives an excellent staining performance afterwards.
Immuno PBS
This solution is developed for use in immuno-
histo-chemistry staining and differs from regular PBS
solutions in buffer composition, ionic strength and
preservative. As a result the antibody coupling is
stronger and a higher specifi city is obtained. Immuno
PBS is a 20-times concentrated solution to be diluted
with de-ionized or distilled water.
Product Product Number Packaging Content
Acetone 3403 Jerrycan 5L, 10L, 25L
Benzylalcohol 3402 Jerrycan 25L
Ethanol 96% 3405 HDPE bottle 2.5L
Jerrycan 5L, 10L, 25L
Ethanol 96% denatured with 5% Methanol 3407 Jerrycan 5L, 10L, 25L
HDPE drum 200L
Ethanol 99% 3406 HDPE bottle, Jerrycan 2.5L, 5L, 10L, 25L
Ethanol 99% denatured with 5% Methanol 3408 Jerrycan 5L, 10L, 25L
Isopropanol 3401 Jerrycan 5L, 10L, 25L
Methanol 3400 HDPE bottle 0.5L
Jerrycan 5L, 10L, 25L
Toluene 3411 Jerrycan 10L
Xylene 3410 HDPE can 2.5L, 5L
Tin can 10L, 25L
UltraPar 3925 PP Drum 5 kg
Rapid Decalcifi er 3930 HDPE bottle 2.5L
Immuno PBS 3058 Cubitainer 10L
Ordering information Alcohols and Solvents, UltraPar, Rapid Decalcifier, Immuno PBS
More Information
For all our Histology products, the Certifi cates of Analysis and Material Safety Data Sheets, please access our
Clinical business group on our website www.mallbaker.com or contact our Customer Service by telephone
0031 570 687500 or send us an e-mail at [email protected]
▲ Particle-free UltraPar
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Part of a pure process™
Mallinckrodt Baker B.V.
Teugseweg 20
P.O. Box 1
7400 AA Deventer
The Netherlands
T 0031 570 687500
F 0031 570 687574
Mallinckrodt Baker UK
107/112 Leadenhall Street
London
EC3A 4AH
United Kingdom
P 0044 1908 506 000
T 0044 1908 503 290
Mallinckrodt Baker Italy
Via P. Portaluppi 11/2
20138 Milano
Italy
P 0039 02 580 891
F 0039 02 580 19 264
Visit us at: www.mallbaker.com
© 2006 Mallinckrodt Baker B.V. Deventer, The Netherlands. All rights reserved.
How to contact Mallinckrodt Baker for your J.T.Baker Products
Contact our international Customer Service at:
Mallinckrodt Baker Germany
Im Leuschnerpark 4
D-64347 Griesheim
Germany
P 0049 6155 667 939
F 0049 6155 667 940
Mallinckrodt Baker France
33 Avenue Phillipe Auguste
75011 Paris
France
P 0033 144 648 971/2
F 0033 144 648 973