hepatitis e virus presentation
TRANSCRIPT
![Page 1: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/1.jpg)
![Page 2: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/2.jpg)
![Page 3: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/3.jpg)
Related to liver inflammation disease
Hepaviridae family, hepevirius genus.
Transmitted through fecal-oral route.
Pregnancy,a most risk factor for HEV
![Page 4: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/4.jpg)
HISTORYFirstly documented in
1955 in Delhi.MS Khuroo in 1980Dr.BayalanMajor Outbreaks
India 1955 Burma 1976 Kashmir 1978 China 1986 Maxico 1989
![Page 5: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/5.jpg)
![Page 6: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/6.jpg)
Signs and symptoms Incubation period It has 2 phases
Prodromal phase Arthralgia Mylegia Fever Anorexia Nausea/vomiting Dehydration
Icteric phase Jaundice Dark urine Light color stools Diarrhea Malaise Pruritus
![Page 7: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/7.jpg)
Prevalence
![Page 8: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/8.jpg)
GENOTY
PES O
F HEV
Genotype 1: has 5 subtypes
Genotype 2 : has 2 subtypes
Genotype 3 : has 10 subtypes
Genotype 4 : has 7 subtypes
![Page 9: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/9.jpg)
GENOME OF HEV
![Page 10: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/10.jpg)
Life cycle of hev
![Page 11: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/11.jpg)
TRANSMISSION OF HEV
•Waterborne transmission• Zoonotic and foodborne
transmission• Vertical transmission• Person-to-person
transmission
![Page 12: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/12.jpg)
DAIGNOSISELISART PCRImmunoflourescentImmune
electronmicroscopy
![Page 13: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/13.jpg)
Treatment
Acute chronic
Treatment ??? Self limitingRibavirin(antiviral drug Interferon Serum immunoglobulin
Infections
![Page 14: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/14.jpg)
PREVENTIONMaintaining
clean waterProper sanitationMaintaining
hygienic practicesAvoid eating
uncooked food
![Page 15: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/15.jpg)
Vaccination
No commercialliazation Recombinant vaccine
Subunit hev vaccine
China,the only producer.
![Page 16: Hepatitis E Virus Presentation](https://reader035.vdocuments.mx/reader035/viewer/2022070518/58e533ed1a28abac7e8b5edf/html5/thumbnails/16.jpg)