hemolytic anemia
DESCRIPTION
Hemolytic anemia. 实验目的 : 掌握溶血性贫血的诊断思路及骨髓象的主要特点。. Hemolytic anemia. Clinical Findings: A 44-year-old female complained of fatigue and weaknessd,frequency and urgency of micturition over the last 2 weeks,she had noticed that her urine was pinkish red in colour. - PowerPoint PPT PresentationTRANSCRIPT
Hemolytic anemia
实验目的 :
掌握溶血性贫血的诊断思路及骨髓象的主要特点。
Hemolytic anemia
Clinical Findings:
A 44-year-old female complained of fatigue and weaknessd,frequency and urgency of micturition over the last 2 weeks,she had noticed that her urine was pinkish red in colour.
On physicial examination,icteric scera and splenomegaly were found.
Hemolytic anemia
Laboratory Findings:
RBC: 2.6×1012/L Hb:85 g/L Ret:10%WBC: 4.7×109/L N:82% L:17% Mo:1%PLT: 164×1012/L Urobilinogen(+) urine bilirubin(++) icteric index:20URous test(-) Hams(-) coombs(+)
Hemolytic anemia
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Hemolytic anemia
骨髓涂片观察及骨髓报告
IDA
实验目的 :
掌握 IDA 的诊断思路及骨髓象的主要特点。
IDA
Clinical Findings:
A ten-year-old boy who came from city gave
chief complaint of having no energy. The
physician found his nail spoon-shaped.
IDA
Laboratory Findings:
Hb 56g/L, RBC 3.5×1012, WBC 10.5×109/L, PLT 200×109/L MCV 68.6fl, MCH 23pg, MCHC 23% Ret 0.5%Serum iron 7.5umol/L TIBC 73umol/L
The peripheral blood smear revealed marked anisocytosi
s, microcytosis hypochromia and poikilocytosis.
IDA
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
IDA
骨髓涂片观察及骨髓报告
IDA
骨髓涂片观察及骨髓报告 Ring cell
IDA
骨髓涂片观察及骨髓报告 basophilic stipping
IDA
骨髓涂片观察及骨髓报告 Howell-Jolly bodies
IDA
骨髓涂片观察及骨髓报告 Howell-Jolly bodies
Megaloblastic anemia(MA)
实验目的 :
掌握 MA 的诊断思路及骨髓象的主要特点。
Megaloblastic anemia(MA)
Clinical Findings:
A 50-year-old female had seen the physician with complaints of having no energy and feeling tired all of the time. She also reported experiencing a mild pain in the abdominal region and having impairment of sensation to pin prick and touch.
Megaloblastic anemia(MA)
Laboratory Findings:
RBC: 1.7×1012/L Hb:62 g/L Ret:0.4%WBC: 4.0×109/L N:62% L:37% Mo:1%PLT: 200×1012/L The peripheral blood smear revealed anisocytosis, poikilocytosis two nucleated RBCs, rare Howell-Jolly bodies and basophilic stipping.
Megaloblastic anemia(MA)
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Megaloblastic anemia(MA)
骨髓涂片观察及骨髓报告 大红细胞
Megaloblastic anemia(MA)
骨髓涂片观察及骨髓报告 红系改变
Megaloblastic anemia(MA)
骨髓涂片观察及骨髓报告 粒系改变
Aplastic anemia
实验目的 :
掌握 AA 的诊断思路及骨髓象的主要特点。
Aplastic anemia
Clinical Findings:
A 22-year-old female gave chief complaint of severe menstrual bleeding recently, and numerous petechiae and some purpura. She told the doctor she had a severe respiratory infection six months age and had taken chloramphenicol for five months. the physical examination revealed no hepatomegaly, splenomegaly and lymphadenopathy.
Aplastic anemia
Laboratory Findings:
RBC: 1.85×1012/L Hb:55 g/L MCV 89fL,MCH 29.7fL,MCHC 31%Ret:0.5%WBC: 2.2×109/L N:38 % L:62%PLT: 35×1012/L
Aplastic anemia
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Aplastic anemia
骨髓涂片观察及骨髓报告 有核细胞增生极度低下
Aplastic anemia
骨髓涂片观察及骨髓报告 非造血细胞增多
Acute lymphocytic leukemia
实验目的 :
掌握 ALL 的诊断思路及骨髓象的主要特点。
Acute lymphocytic leukemia
Clinical Findings:
A 5-year-old girl was taken to the emergency roomby her mother,because of an elevated temperture that could not be controlled by aspirn.the patient complained of a sore throat and ear for the last several days.Physical examination revealed a well-nourished but listless child,the tympanic membrane was inflamed.the child had both lymphadenopathy and hepatosplenomegaly.
Acute lymphocytic leukemia
Laboratory Findings:
RBC: 1.7×1012/L Hb:62 g/L WBC: 40×109/L lymphoblasts and prolymphocytes:80%L:12% N:8%PLT: 200×1012/L
Acute lymphocytic leukemia
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Acute lymphocytic leukemia
骨髓涂片观察及骨髓报告 ALL-L1
Acute lymphocytic leukemia
骨髓涂片观察及骨髓报告 ALL-L2
Acute lymphocytic leukemia
骨髓涂片观察及骨髓报告 ALL-L3
AML-M2a
实验目的 :
掌握 M2a 的诊断思路及骨髓象的主要特点。
AML-M2a
Clinical Findings:
A 32-year-old female patient complained of fatigue for two days. The doctor noticed that she looked pale and weakness and found some unexplained large bruises on her skin. Hepatomegaly and sternal tenderness was present, but lymphadenopathy was absent.
AML-M2a
Laboratory Findings:
RBC: 3.3×1012/L Hb:70 g/L WBC: 21×109/L DC: Immature cells :91% N:7% L:1% E:1%PLT: 45×109/L
AML-M2a
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
AML-M2a
骨髓涂片观察及骨髓报告
AML-M3 (APL)
实验目的 :
掌握 M3 的诊断思路及骨髓象的主要特点。
AML-M3 (APL)
Clinical Findings:
A female paitient , 36-year-old, complained of fatigue and weakness for more than half a month, and bleeding gums for five days. The physical examination revealed sternal tenderness, without hepatosplenomegaly.
AML-M3 (APL)
Laboratory Findings:
RBC: 3.6×1012/L Hb:86 g/LWBC: 2.8×109/L DC: Immature cells 73% ; Bands 3% ; Seg. 6%; E 1%; L 17%PLT: 30×1012/L
AML-M3 (APL)
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
AML-M3 (APL)
骨髓涂片观察及骨髓报告 AML-M3a
AML-M3 (APL)
骨髓涂片观察及骨髓报告 AML-M3a
AML-M3 (APL)
骨髓涂片观察及骨髓报告 AML-M3b
AML-M3 (APL)
骨髓涂片观察及骨髓报告 Faggot cell
AML-M3 (APL)
骨髓涂片观察及骨髓报告 t(15;17)
AML-M5
实验目的 :
掌握 M5 的诊断思路及骨髓象的主要特点。
AML-M5
Clinical Findings:
A 38-year-old female patient came to the hospital because she had been suffering from swollen, bleeding gums for several weeks. The physician noticed that she was pale and febrile, and had hepatomegaly, splenomegaly and lymphodenopathy.
AML-M5
Laboratory Findings:
Hb 90g/L, RBC 3.0×1012 WBC 32×109/L, DC: Immature cells 95% ; Monocytes 4.0% ; L 1.0%PLT 35×109/L
AML-M5
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
AML-M5 (APL)
骨髓涂片观察及骨髓报告 ( AML-M5a)
AML-M5 (APL)
骨髓涂片观察及骨髓报告 ( AML-M5b)
Chronic Myeloid Leukemia
实验目的 :
掌握 CML 的诊断思路及骨髓象的主要特点。
Chronic Myeloid Leukemia
Clinical Findings:
A 65-year-old male give chief complaint of feeling tired for 2 years. The physician noticed found the spleen enlarged and others were negative.
Chronic Myeloid Leukemia
Laboratory Findings:
RBC: 3.0×1012/L Hb:86 g/LWBC: 145×109/L DC: Immature cells 60% ; Bands 15% ; Seg. 13%; B 6%; E 5% ; M 1 %PLT: 400×1012/L
Chronic Myeloid Leukemia
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Chronic Myeloid Leukemia
骨髓涂片观察及骨髓报告
Chronic Myeloid Leukemia
骨髓涂片观察及骨髓报告 t(9;22)
Multiple Myeloma (MM)
实验目的 :
掌握 MM 的诊断思路及骨髓象的主要特点。
Multiple Myeloma (MM)
Clinical Findings:
a 58-year-old male gave chief complaint of increasing fatigue and pain in his lower back when he walked .
Multiple Myeloma (MM)
Laboratory Findings:
Hb 85g/l RBC 3.2×1012/l WBC 5.6×109/l PLT 300×109/l ESR 50mm/hour X-ray indicated bone lesions in various sites
Multiple Myeloma (MM)
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Multiple Myeloma (MM)
骨髓涂片观察及骨髓报告 Myeloma cell
Multiple Myeloma (MM)
骨髓涂片观察及骨髓报告 Flame cell
Multiple Myeloma (MM)
骨髓涂片观察及骨髓报告 Mott cell
Multiple Myeloma (MM)
骨髓涂片观察及骨髓报告 Rouleaus—like formationRouleaus—like formation
Idiopathic Thrombocytopenic purpura (ITP)
实验目的 :
掌握 ITP 的诊断思路及骨髓象的主要特点。
Idiopathic Thrombocytopenic purpura (ITP)
Clinical Findings:
A 35-year-old women was admitted with complaint of bleeding of gum, purpura of the legs for 15 years, becoming severe in the last 10 days accompained with nasobleed recurrent and macroscropic hematuria. The patient was consciousness and pale, scattered hemorrhagic spots occur anywhere on the skin .The spleenmegaly was present.
Idiopathic Thrombocytopenic purpura (ITP)
Laboratory Findings:
RBC:3.1×10 12/L Hb 125g/L PLT 32×109/LBT > 10min CT 8min WBC 8×109/L Neutrophils:77% Eosinophils: 2% Lymphocytes:16% Monocytes: 5%
Idiopathic Thrombocytopenic purpura (ITP)
Questions:
1 what is the most probable diagnosis in this case?2 what are the diagnostic bases?3 what additional tests are need to establish the diagnosis?
Idiopathic Thrombocytopenic purpura (ITP)
骨髓涂片观察及骨髓报告