helminths escmid online lecture library lumc-parasitology
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Department of ParasitologyLeiden University Medical Centre
Helminths
Nematodes (roundworm)• geohelminths• Strongyloides
Cestodes (tapeworm)• Taenia• Echinococcus
Trematodes (flukes)• Schistosoma• Food born trematodesLU
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Department of ParasitologyLeiden University Medical Centre
Size range of human tapeworms (cestodes)
Taenia saginata/T. solium
2 - 8 meter
Hymenolepis nana
1.5 - 4 cm
dwarf tapeworm
large tapeworm
4 -10 meter
broad tapeworm
Diphyllobothrium latumLUMC-P
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Department of ParasitologyLeiden University Medical Centre
Taeniasis
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Taenia solium - cysticercosis
• Human ingestion of eggs• Oncosphere develops into cysticerci
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Department of ParasitologyLeiden University Medical Centre
Taenia solium - cysticercosis
• Human ingestion of eggs• Oncosphere develops into cysticerci• Muscles, subcutaneous• Brain => neurocysticercosis
• Time delay
• Imaging, serology, (antigen detection, PCR)
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Department of ParasitologyLeiden University Medical Centre
Taenia solium - cysticercosis
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Department of ParasitologyLeiden University Medical Centre
Taenia solium - cysticercosis
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Taenia saginata / Taenia solium• embryonated oncosphere, 6 hooks• radially striated brown shell (embryophore)• primary membrane (egg shell)
≈ 35 µm
Pollen artefact
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Department of ParasitologyLeiden University Medical Centre
Taenia saginata / Taenia solium
Scolex with 4 suckers Scolex with 4 suckers + double row of hooks
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Taenia saginata - Taenia solium
• 15 to 20 branches on each side • 7 to 13 branches on each side
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Hymenolepis nana - dwarf tapeworm
Adult worms:
15 to 40 mm in length
The life span 4-6 weeks,
Autoinfections
Intestinal cysticeric
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Hymenolepis nana - dwarf tapeworm
52x40 µm
two membranes
4-8 polar filaments
Oncosphere: six hooksLUMC-P
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Department of ParasitologyLeiden University Medical Centre
Other cestodes a.o.:
Hymenolepis diminuta rat tapeworm
Dipylidium caninumdog/cat tapeworm
Bertiella spp.tapeworm of non human primates
Diphyllobothrium latumbroad fish tapeworm
Echinococcus spp.dog tapewormfox tapeworm
65x60 µm
65x45 µm
artefact
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Diphyllobotrium latum
Knop Operculum
± 65x45 µm
Ned. Tijdschr Geneeskd(2005) 149(44): 2470LU
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Department of ParasitologyLeiden University Medical Centre
€ 2.60 voor 6 st.
€ 0.90 voor 2 st. € 1.30 voor 2 st.LUMC-P
arasit
ology
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Department of ParasitologyLeiden University Medical Centre
<= taeniasis , 2e keuze PZQ
<= ???
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