h-tert cell line
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h-TERT cell line. - PowerPoint PPT PresentationTRANSCRIPT
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h-TERT cell line
An hTERT cell line is one that has been immortalized by inserting the hTERT (human telomerase reverse transcriptase) gene into the cells' DNA. This gene immortalizes cells by maintaining telomere ends. This prevents the telomere shortening of a cell's DNA which would otherwise cause the cells to senesce.
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Recurrent SETBP1 mutations in childhood Acute myeloid
Leukemia
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Nature Genet-ics
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Nature Genet-ics
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Primer name Primer sequences(5'-3')SETBP1-forward CCACTTTCAACACAGTTAGGTG SETBP1-Reverse TCTCGTGGTAGAAGGTGTAACTC
Amino acid number 778~979
Nature Genet-ics
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C2903 (ser869)
C2903T/C (ser869)Patient No.44
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Tumor type Number of samples Number of mutated samples
Percent mu-tated samples
childhood AML 55 0 0