growth factor and sleep-related quality of life in children
TRANSCRIPT
METHOD: Retrospective chart review in the biggest pediatrichospital in Lisbon (Portugal). Between 2003 and 2008, 254pediatric patients were codified as tympanoplasty (ICD-9).Only 93 were included in this study: simple perforation, chil-dren younger than 15y, and follow-up longer than 1y. Re-viewed factors included: gender, age, disease in the contralat-eral ear, local and size of perforation, and pre-operativetympanometric volume. The Chi-square and T student testwere used for comparing the variables between the failure andsuccess group.RESULTS: The overall failure rate of tympanoplasty was29% (22 reperforations, three otitis with effusion, two atelec-tasis). The mean age of the failure group was 9y comparedwith 11y in the success group (p�0.28). The failure rate was34% in boys compared with 26% in girls (r�0.1), and 50% incases with anterior perforation compared with 26% in centralperforation. The failure rate was similar when we comparedthe group with normal and the group with abnormal contralat-eral ear (r�0.08). When we established a cut-off value of 3.5ccin the tympanometric volume, the failure rate was 27% (forvolumes greater than 3.5 cc) compared with 42% (for volumesunder 3.5cc). In the group with 4-7 year olds (N�21), thefailure rate was 43% compared with 26% in the group with8-15 year olds (N�72). In the former, the tympanometricvolume was 3.42 cc in the success group and 2.56cc in thefailure group (p�0.13).CONCLUSION: The gender (boys), children younger thaneight years old, the anterior perforations, and the tympanomet-ric volume less than 3.5cc seems to be important predictivefactors of failure in tympanoplasty in children.
The Foreign Bodies in Respiratory Tract in Children
Elena Merkulava, MD, PhD (presenter)
OBJECTIVE: The analysis of the causes and features of clin-ical pictures of airway foreign bodies (FB) in children.METHOD: We have made the retrospective analysis of clin-ical records for 45 cases of aspiration of FB during 2005-2009years.RESULTS: Airway FB are diagnosed significantly more oftenin children younger than one year of age (N�24; 53%). Themost often aspiration of FB takes place at home (N�31; 69%;p�0.05). The infringement of child feeding culture is signifi-cantly more often the cause of aspiration of FB in airways,since in 35 cases of 45, organic foreign bodies in the form offood slices were found (p�0.05). Depending on the level ofobturation causing a clinical picture, it was subdivided into FBof throats/laryngopharynx (n�6), trachea (n�1), right (n�14)and left (n�14) main bronchus, and also plural FB, obturatinga lumen of the primary, lobar, and sometimes segmental bron-chus (n�10).CONCLUSION: High frequency of aspiration of airway FBin children younger than one year of age and the prevalence of
domiciliary cases testify that the increase of parents’ respon-sibility in child care results in the prevention of aspiration ofFB in children.
Growth Factor and Sleep-Related Quality of Life in
Children
Sung Wan Kim, MD, PhD (presenter)
OBJECTIVE: Tonsils and adenoids affect the growth of chil-dren. It has been reported that growth factor was significantlyincreased after adenotonsillectomy. In addition, it was reportedthat tonsil and adenoid hypertrophy affected the growth hor-mone and quality of sleep, but that has not been well re-searched. The aim of this study is thus to analyze factorsaffected in the growth of children with tonsil and adenoidhypertrophy.METHOD: Fifty children, 34 boys and 16 girls, with plannedadenotonsillectomy due to snoring and repeated sore throatwere selected. Average age was 7.3 years. Children with otherdiseases affected in growth were excluded. All children hadwrist X-rays taken, and height and weight measured. We eval-uated the growth state of children with insulin-like growthfactor (IGF)-1 and IGF-binding protein (BP)-3. OSA-18 qual-ity of life questionnaire was performed for sleep-related qualityof life assessment. Survey was filled in by parents.RESULTS: Twenty pediatric patients had height under 10thpercentile, compared with those of the same age. And 29pediatric patients had abnormality of growth on the wrist X-ray. Six (60%) of pediatric patients with height under 10thpercentile had low serum level of IGF-1, and their mean totalscore of OSA-18 quality of life questionnaire was 65.6. Tocompare with normal pediatric patients, they had significantlypoorer quality of life and related sleep. Nine (31%) of pediatricpatients showed abnormality of growth on wrist X-ray, andtheir mean total score of OSA-18 quality of life questionnairewas 57. There was no significant difference to compare withnormal group.CONCLUSION: Children with adenoid and tonsil hypertro-phy have frequent growth problems. We could see that growthhormone and related factors are important in the growth ofchildren. And the quality of life related sleep of children withlow serum IGF-1 level and short stature is not good.
Guillotine vs Dissection Tonsillectomy: A
Prospective Study
Parmod Jain, MBBS, DLO, DLORCS, MS(presenter); Matthew Ward, MRCS DOHNS; HasnaaIsmail-Koch, MRCS, DLO, MD, FRCS; VishnuSunkaraneni, LLM, FRCS; Rami J Salib, PhD
OBJECTIVE: 1) Determine whether there is a difference inoperative time, intra-operative blood loss and post-operativepain. 2) Determine whether there is a difference in post-oper-ative complications.
P258 Otolaryngology-Head and Neck Surgery, Vol 143, No 2S2, August 2010