GROWTH ALTERATIONGROWTH ALTERATION

► CausesCauses► SymptomsSymptoms► ConsequencesConsequences► TreatmentsTreatments► PreventionPrevention► Goals for the futureGoals for the future► People affectedPeople affected

CAUSESCAUSES

► Mutation of specific Mutation of specific genesgenes

► Congenital diseases or Congenital diseases or malformationsmalformations

► Intracranial tumorsIntracranial tumors► Severe cranial Severe cranial

traumatismtraumatism► Autoimmune Autoimmune

inflamation inflamation (hypohysitis)(hypohysitis)

► Bad nutritionBad nutrition

SYMPTOMSSYMPTOMS

► It is impossible to It is impossible to define the symptoms define the symptoms because there are because there are many because growth many because growth alteration can be alteration can be produced by various produced by various pathological pathological circumstances.circumstances.

► But one of them can be But one of them can be alteration in growth of alteration in growth of stature that is very stature that is very common, like delays in common, like delays in growth.growth.

CONSEQUENCESCONSEQUENCES

Some consequences are:Some consequences are:

►Degeneration and dystrophy (the Degeneration and dystrophy (the muscles weaken as time passes).muscles weaken as time passes).

►Alteration of the circulation.Alteration of the circulation.► Inflammation.Inflammation.►Deformity of muscles.Deformity of muscles.►Alteration in stature.Alteration in stature.

TREATMENTSTREATMENTS

DAILY INJECTIONS OF DAILY INJECTIONS OF GROWTH HORMONEGROWTH HORMONE

► Injections of GH into Injections of GH into the bloodthe blood

► Successful in childrenSuccessful in children► Less effetiveness in Less effetiveness in

adultsadults

BONE STRETCHINGBONE STRETCHING

► Surgery to strech the Surgery to strech the legs graduallylegs gradually

► Recommended to Recommended to children whose bones children whose bones are still growingare still growing

► Risk of infectionRisk of infection

PREVENTIONPREVENTION

►The prevention starts by weighing and The prevention starts by weighing and measuring our children when they are measuring our children when they are small. You have to bring your child to small. You have to bring your child to the doctor to make him a growth exam. the doctor to make him a growth exam. This should be done periodically.This should be done periodically.

►To diagnose an alteration in growth To diagnose an alteration in growth doctors should weigh and measure the doctors should weigh and measure the child and draw a chart showing their child and draw a chart showing their growth curve.growth curve.

GROWTH CURVEGROWTH CURVE

Goals for the futureGoals for the future

►Right now for some alterations of Right now for some alterations of growth we use growth hormone, which growth we use growth hormone, which is a peptide hormone that stimulates is a peptide hormone that stimulates growth and has no secondary effects.growth and has no secondary effects.

►For the future, it is expected to For the future, it is expected to improve, but now it is still being improve, but now it is still being investigated.investigated.

PEOPLE AFFECTEDPEOPLE AFFECTED

► There are spontaneous cases all around the There are spontaneous cases all around the worldworld

► Growth alteration is more common in boys than Growth alteration is more common in boys than in girlsin girls

► It affects to 1 of every 4000 childrenIt affects to 1 of every 4000 children