gregor mendel, 1822-1884 and why we look the way we...
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L. Coleman 2009
J. Mitchell 2012
L. Coleman 2009
Gregor Mendel, 1822-1884
And why we look the way we do
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Gregor Mendel was a priest in what is now the
Czech Republic. He was a high school science
teacher and keeper of the monastery garden.
Mendel’s monastery today. Mendel’s garden.
His curiosity about heredity led him do
numerous experiments on pea plants. His results
and conclusions written in 1865 are the foundation
of modern genetics.
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• Mendel’s experiments led him to make conclusions about genetics that are still used today and form the foundation of modern genetics.
• One reason his findings are so remarkable is that so little was known then about reproduction at the cellular level. Mendel didn’t know about:
1. Genes
2. Chromosomes (people had seen
them but didn’t know they were
involved in heredity.
3. Meiosis (no one knew how gametes
form)
4. DNA
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What did Mendel find?
• He discovered different laws and rules that explain factors affecting heredity.
• Heredity: how traits are passed on.
• Traits: characteristics
–Example: blue eyes, brown hair, or cleft chin
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Rule of Unit Factors • ... states that each organism has
two alleles for each trait (located on homologous chromosomes).
• Alleles: different forms of the same gene – Example: B = brown eyes; b = blue
eyes
• Gene: a sequence of DNA bases that specify the order of amino acids in a protein.
– Controls how an organism develops
Chromosome DNA
Gene 1
Gene 2
Allele B
Allele
b
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Rule of Dominance
• The trait that is observed in the offspring is the dominant trait (uppercase) – Example: B = brown eyes
• The trait that disappears in the offspring is the recessive trait (lowercase) – Example: b = blue eyes
B
b
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• Genotype: the combination of alleles an organism has.
• Phenotype: physical appearance OR what the traits look like.
– Example: bb, BB, or Bb
– A blue eyed person’s genotype is bb.
– A brown-eyed person’s genotype could be BB or Bb.
Why doesn’t someone with genotype Bb have BLUE eyes?
– Example: Ms. Mitchell’s phenotype for hair color
is brown hair.
bb
b b
What is YOUR phenotype for hair color?
What is YOUR phenotype for eye color?
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• Homozygous: Both alleles for a trait are the same.
• Heterozygous: The organism's alleles for a trait are different.
– Example: bb or BB
– Example: Bb or Aa
Use any letter to come up with an example of a homozygous genotype.
Use any letter to come up with an example of a heterozygous genotype.
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Law of Segregation
• A parent randomly passes only one allele for each trait in each gamete to each offspring
• Fertilization: when two gametes (1 from each parent) join together to form a new organism.
The Law of Segregation states that the two alleles for a trait must separate when gametes are formed.
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Law of Independent Assortment
• … states that the genes for different traits are inherited independently of each other.
– Genes for different traits can segregate independently during the formation of gametes (meiosis).
gametes
MEIOSIS
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Review Questions • How many alleles are there for each trait? – 2 alleles
• What is an allele? – different forms of the same gene
• How many alleles does a parent pass on to each offspring for each trait? – 1 allele for each trait for each offspring
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• Purebreeding (pure): offspring that are the result of mating between genetically similar kinds of parents.
– the opposite of hybrid.
• Hybrids: offspring that are the result of mating between 2 genetically different kinds of parents. − the opposite of purebreed
F1
F1
P = parents F1 = 1st generation
P
P