graeco - latin square designs-02

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5. Process Improvement 5.3. Choosing an experimental design 5.3.3. How do you select an experimental design? 5.3.3.2. Randomized block designs These designs handle 3 nuisance factors Graeco-Latin squares, as described on the previous page, are efficient designs to study the effect of one treatment factor in the presence of 3 nuisance factors. They are restricted, however, to the case in which all the factors have the same number of levels. Randomize as much as design allows Designs for 3-, 4-, and 5-level factors are given on this page. These designs show what the treatment combinations would be for each run. When using any of these designs, be sure to randomize the treatment units and trial order, as much as the design allows. For example, one recommendation is that a Graeco-Latin square design be randomly selected from those available, then randomize the run order. Graeco-Latin Square Designs for 3-, 4-, and 5-Level Factors Designs for 3-level factors 3-Level Factors X1 X2 X3 X4 row blocking factor column blocking factor blocking factor treatment factor 1 1 1 1 1 2 2 2 1 3 3 3 2 1 2 3 2 2 3 1 2 3 1 2 3 1 3 2 3 2 1 3 3 3 2 1 with 5.3.3.2.2. Graeco-Latin square designs http://www.itl.nist.gov/div898/handbook/pri/section3/pri3322.ht m 1 of 4 11/22/2013 8:38 PM

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Graeco-Latin Square Design Approaches

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Page 1: Graeco - Latin Square Designs-02

5. Process Improvement5.3. Choosing an experimental design5.3.3. How do you select an experimental design?5.3.3.2. Randomized block designs

Thesedesignshandle 3nuisancefactors

Graeco-Latin squares, as described on the previous page, areefficient designs to study the effect of one treatment factor inthe presence of 3 nuisance factors. They are restricted,however, to the case in which all the factors have the samenumber of levels.

Randomizeas much asdesignallows

Designs for 3-, 4-, and 5-level factors are given on this page.These designs show what the treatment combinations would befor each run. When using any of these designs, be sure torandomize the treatment units and trial order, as much as thedesign allows.

For example, one recommendation is that a Graeco-Latinsquare design be randomly selected from those available, thenrandomize the run order.

Graeco-Latin Square Designs for 3-, 4-, and 5-LevelFactors

Designs for3-levelfactors

3-Level FactorsX1 X2 X3 X4row

blockingfactor

columnblocking

factor

blockingfactor

treatmentfactor

1 1 1 11 2 2 21 3 3 32 1 2 32 2 3 12 3 1 23 1 3 23 2 1 33 3 2 1

with

5.3.3.2.2. Graeco-Latin square designs http://www.itl.nist.gov/div898/handbook/pri/section3/pri3322.htm

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Page 2: Graeco - Latin Square Designs-02

k = 4 factors (3 blocking factors and 1 primary factor)L1 = 3 levels of factor X1 (block)L2 = 3 levels of factor X2 (block)L3 = 3 levels of factor X3 (primary)L4 = 3 levels of factor X4 (primary)N = L1 * L2 = 9 runs

This can alternatively be represented as (A, B, and C representthe treatment factor and 1, 2, and 3 represent the blockingfactor):

A1 B2 C3C2 A3 B1B3 C1 A2

Designs for4-levelfactors

4-Level FactorsX1 X2 X3 X4row

blockingfactor

columnblocking

factor

blockingfactor

treatmentfactor

1 1 1 11 2 2 21 3 3 31 4 4 42 1 2 42 2 1 32 3 4 22 4 3 13 1 3 23 2 4 13 3 1 43 4 2 34 1 4 34 2 3 44 3 2 14 4 1 2

with

k = 4 factors (3 blocking factors and 1 primary factor)L1 = 3 levels of factor X1 (block)L2 = 3 levels of factor X2 (block)

5.3.3.2.2. Graeco-Latin square designs http://www.itl.nist.gov/div898/handbook/pri/section3/pri3322.htm

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Page 3: Graeco - Latin Square Designs-02

L3 = 3 levels of factor X3 (primary)L4 = 3 levels of factor X4 (primary)N = L1 * L2 = 16 runs

This can alternatively be represented as (A, B, C, and Drepresent the treatment factor and 1, 2, 3, and 4 represent theblocking factor):

A1 B2 C3 D4D2 C1 B4 A3B3 A4 D1 C2C4 D3 A2 B1

Designs for5-levelfactors

5-Level FactorsX1 X2 X3 X4row

blockingfactor

columnblocking

factor

blockingfactor

treatmentfactor

1 1 1 11 2 2 21 3 3 31 4 4 41 5 5 52 1 2 32 2 3 42 3 4 52 4 5 12 5 1 23 1 3 53 2 4 13 3 5 23 4 1 33 5 2 44 1 4 24 2 5 34 3 1 44 4 2 54 5 3 15 1 5 45 2 1 5

5.3.3.2.2. Graeco-Latin square designs http://www.itl.nist.gov/div898/handbook/pri/section3/pri3322.htm

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Page 4: Graeco - Latin Square Designs-02

5 3 2 15 4 3 25 5 4 3

with

k = 4 factors (3 blocking factors and 1 primary factor)L1 = 3 levels of factor X1 (block)L2 = 3 levels of factor X2 (block)L3 = 3 levels of factor X3 (primary)L4 = 3 levels of factor X4 (primary)N = L1 * L2 = 25 runs

This can alternatively be represented as (A, B, C, D, and Erepresent the treatment factor and 1, 2, 3, 4, and 5 representthe blocking factor):

A1 B2 C3 D4 E5C2 D3 E4 A5 B1E3 A4 B5 C1 D2B4 C5 D1 E2 A3D5 E1 A2 B3 C4

Furtherinformation

More designs are given in Box, Hunter, and Hunter (1978).

5.3.3.2.2. Graeco-Latin square designs http://www.itl.nist.gov/div898/handbook/pri/section3/pri3322.htm

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