gobind gill vasopressin. structure
TRANSCRIPT
Structure
http://upload.wikimedia.org/wikipedia/commons/thumb/c/c6/Arginine_vasopressin3d.png/778px-Arginine_vasopressin3d.png
Background
HypothalamusPituitary GlandStimuliiFunctions
Water retention in kidney Blood vessel constriction
Site of Action in Kidney
http://faculty.pasadena.edu/dkwon/chapter%2020/Chapter%2020_A_files/slide0056_image007.jpg
Mechanism of Action
http://faculty.pasadena.edu/dkwon/chapter%2020/Chapter%2020_A_files/slide0056_image008.jpg
Vasopressin-Related Disorders
Central diabetes insipidus Thirst Dehydration Large volume of dilute urine Treatment: desmopressin
Hyponatremia Low blood osmolarity Increased water retention Side effects: headache, nausea vomiting, fatigue, loss
of apetite Treatment: VR2 agonist