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  • 8/10/2019 GNIPST Bulletin 39.3

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    21stNovember, 2014 Volume No.: 39 Issue No.: 03

    Vision

    TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BAS

    LEARNING AND PRACTICE

    ontentsMessage from PRINCIPAL

    Editorial board

    Historical article

    News Update

    Knowledge based Article

    Disease Related Breaking

    News

    Upcoming Events

    Drugs Update

    Campus NewsStudents Section

    Editors Note

    Archive

    GNIPST Photo Gallery

    or your comments/contribution

    For ack-Issues,

    ailto:[email protected]

    GURU NANAK INSTITUTE OF PHARMACEUTICAL

    SCIENCE AND TECHNOLOGY

    Website:http://gnipst.ac.in

    https://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7mailto:[email protected]:[email protected]:[email protected]://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7
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    MESSAGE FROM PRINCIPAL

    "It can happen. It does happen.

    But it can't happen if you quit." Lauren Dane.

    We are what we repeatedly do.

    Excellence then is not an act, but a habit. Aristotle

    It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank tlast years editors and congratulate the newly selected editors for the current year.

    Our first consideration is always in the best interest of the students. Our goal is to promote academexcellence and continuous improvement.

    I believe that excellence in education is aided by creating a learning environment in which all learners asupported in maximizing their potential and talents. Education needs to focus on personalized learni

    and instruction, while promoting an education system that is impartial, universally accessible, and meeti

    the needs of all students.

    It is of paramount importance that our learners have sufficient motivation and encouragement in order achieve their aims. We are all very proud of you, our students, and your accomplishments and loo

    forward to watching as you put your mark on the profession in the years ahead.

    The call of the time is to progress, not merely to move ahead. Our progressive Management is looki

    forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken

    this direction and fruits of these efforts will be received by our students in the near future. Our Teache

    are committed and dedicated for the development of the institution by imparting their knowledge and pl

    the role of facilitator as well as role model to our students.

    The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positi

    challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holist

    needs of our students.

    I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of t

    opportunities and meet the challenges with purpose and determination.

    Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us

    this path.

    My best wishes to all.

    Dr. A. Sengupta

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    EDITORIAL BOARD

    CHIEF EDITOR DR. ABHIJIT SENGUPTA

    EDITOR MS. JEENATARA BEGUM

    ASSOCIATE EDITOR MR. DIPANJAN MANDAL

    HISTORICAL ARTICLE

    The First Official Pharacopeia:The idea of a pharmacopoeia with official status, to be followed byall apothecaries, originated in Florence. The Nuovo Receptario,originally written in Italian, was published and became the legalstandard for the city-state in 1498. It was the result ofcollaboration of the Guild of Apothecaries and the Medical Society- one of the earliest manifestations of constructiveinterprofessional relations. The professional groups receivedofficial advice and guidance from the powerful Dominican monk,Savonarola, (seated, foreground) who, at the time, was the politicalleader in Florence.

    NEWS UPDATE

    Brain injuries in mice treated using bone marrow

    stem cells, antioxidants: (21stNovember, 2014)For the first time, researchers have transplanted bone marrowstem cells into damaged brain tissue while applying lipoic acid (apotent antioxidant), with the aim of improving neuroregenerationin the tissue. This new way of repairing brain damage, whichcombines cellular treatment with drug therapy, has shown positive

    results, especially in forming blood vessels (a process calledangiogenesis) in damaged areas of the brains of adult laboratorymice.

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    Novel robotic walker helps patients regain

    natural gait and increases productivity of

    physiotherapists: (21stNovember, 2014)Survivors of stroke or other neurological conditions such as spinalcord injuries, traumatic brain injuries and Parkinsons diseaseoften struggle with mobility. To regain their motor functions,these patients are required to undergo physical therapy sessions. Ateam of researchers has invented a novel robotic walker that helpspatients carry out therapy sessions to regain their leg movementsand natural gait. The system also increases productivity ofphysiotherapists and improves the quality of rehabilitation

    sessions.Teasing out glitches in immune system's self-

    recognition: (21stNovember, 2014)In order to distinguish self from other, the immune systemprocesses proteins from inside and outside the body in differentways. A new study revises understanding of how the processworks and sheds light on autoimmune disease.

    Novel regulatory mechanism for cell divisionfound: (21stNovember, 2014)A protein kinase or enzyme known as PKM2 has proven to controlcell division, potentially providing a molecular basis for tumordiagnosis and treatment, researchers report. Understanding howcytokinesis goes awry is important since abnormal cell divisionimpacts tumor cell growth and spread, they add.

    Key protein decrypted: Scientists develop 3D

    model of regulator protein bax: (21stNovember,2014)A new 3D model of the protein Bax, a key regulator of cell death,has been developed and released by researchers. When active, Baxforms pores in the membranes of mitochondria, causing the release

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    of proteins from the intermembrane space into the cytoplasm. Thisin turn triggers a series of operations ending in cell death, whichare often impaired in cancer cells. Using Double Electron-ElectronResonance spectroscopy, the research group has now shown that

    active Bax is present on the membrane in the form of dimericassemblies whose clamp-like structures have a central role in thepore formation process.

    Tapeworm found living inside a patient's brain:

    Worm removed and sequenced: (20thNovember,

    2014)A genome of a rare species of tapeworm found living inside a

    patient's brain has been sequenced for the first time. The studyprovides insights into potential drug targets within the genome forfuture treatments.

    How mutant gene can cause deafness: (20th

    November, 2014)Scientists have discovered how one gene is essential to hearing,uncovering a cause of deafness and suggesting new avenues fortherapies. "This raises hopes that we could, in principle, use gene-

    therapy approaches to restore function in hair cells and thusdevelop new treatment options for hearing loss," said the seniorauthor of the new study.

    First inhibitor for enzyme linked to cancers

    created: (20thNovember, 2014)Recent studies showing acid ceramidase (AC) to be upregulated inmelanoma, lung and prostate cancers have made the enzyme adesired target for novel synthetic inhibitor compounds. Nowscientists describe the very first class of AC inhibitors that may aidin the efficacy of chemotherapies.

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    When vaccines are imperfect: What math can

    tell us about their effects on disease

    propagation: (20thNovember, 2014)The control of certain childhood diseases is difficult, despite highvaccination coverage in many countries. One of the possiblereasons for this is 'imperfect vaccines,' that is, vaccines that faileither due to 'leakiness,' lack of effectiveness on certain individualsin a population, or shorter duration of potency. In a new article,authors use a mathematical model to determine the consequencesof vaccine failure and resulting disease dynamics.

    Pain, magnet displacement in MRI in patients

    with cochlear implants: (20thNovember, 2014)Pain, discomfort and magnet displacement were documented in asmall medical records review study of patients with cochlearimplants who underwent magnetic resonance imaging (MRI),according to a new report.

    New device reduces scarring in damaged blood

    vessels: (20thNovember, 2014)

    A new device contains a form of vitamin A that controlsinflammatory responses, preventing scar tissue formation andpromoting wound healing. The soft, porous, and thin elasticmaterial contains an acid form of vitamin A, called a retinoid,which is produced by the body to help cells develop and stayhealthy. Synthetic retinoids have been formulated and traditionallyused to treat acne and some types of cancer.

    HIV/AIDS drugs could be repurposed to treat

    AMD, researchers suggest: (20th November,2014)Drugs that have been used for the past 30 years to treat HIV/AIDS,could be repurposed to treat the dry form of age-related maculardegeneration (AMD), a new study suggests. AMD is a progressive

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    condition that is untreatable in up to 90 percent of patients and isa leading cause of blindness in the elderly worldwide. The twoforms of AMD, wet and dry, are classified based on the presence orabsence of blood vessels that have invaded the retina.

    For detail mail toeditor

    KNOWLEDGE BASED ARTICLE

    Cohesin molecule safeguards cell divisionThe ring-shaped cohesin complex ensures that each round ofcell division yields two daughter cells with identical sets ofchromosomes. The peculiar molecule and its function were

    discovered in Kim Nasmyths lab at the IMP in 1997. Theconclusions that the researchers drew from their observationsback then were unexpected. A molecule shaped like a ring wasproposed to hold the two nascent DNA-strands together - muchlike a rubber band - until the exact moment had arrived forseparation. Only then would the ring snap open and release thetwo copies of chromosomes on which the genetic information isstored.

    In the following years, this mechanism was not only confirmedbut further and far-reaching functions of cohesin werediscovered, such as its importance for DNA damage repair andfor the structure of chromatin. However, cohesin itself wasnever seen in action. In the living cell, the opening of the ring isan extremely fast process and doesnt last long enough to becaptured.Recently research have been found the indirect way ofvisualizing cohesin at the moment when it opens up and releases

    DNA. After toiling with the problem for five years, it is now ableto construct a synthetic cohesin molecule from its molecularbuilding blocks. The method involves infecting cultured ovariancells from the army worm with baculoviruses to engineer thenecessary proteins.

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    mailto:[email protected]:[email protected]:[email protected]
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    By inserting mutations, the cohesin was force to be in open formand remain there. A transmission electron microscope and a72,000-fold magnification then did the trick and cohesins openstate was for the first time captured on screen. The images show

    tiny structures with two thread-like arms, connected by amolecular hinge. A more poetic association that comes to mindis that of a pair of ripe cherries.For researchers in the field of cell and structural biology, theconfirmation of the postulated mechanism of action is animportant step towards understanding the details of celldivision.Elucidating the function of Cohesin is also highly relevant for

    human medicine. Jan-Michael Peters explains why: A numberof tumors are associated with mutations in cohesin genes,among them certain forms of leukemia and bladder cancer.Mistakes in cell division, caused by malfunctioning cohesin, canalso lead to chromosomal aberrations like trisomy 21 (Downsyndrome). Even the age-related decrease in female fertility anda high percentage of spontaneous miscarriages are attributed tocohesin defects.

    Jeenatara BegumAssistant Professor

    GNIPST

    DISEASE RELATED BREAKING NEWS

    Human infection with avian influenza A(H7N9)

    virus China: (18thNovember, 2014)

    On 15 November 2014, the National Health and Family PlanningCommission (NHFPC) of China notified WHO of 3 additionallaboratory-confirmed cases of human infection with avianinfluenza A(H7N9) virus, including 1 death.Read more

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    http://www.who.int/csr/don/18-november-2014-avian-influenza/en/http://www.who.int/csr/don/18-november-2014-avian-influenza/en/
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    UPCOMING EVENTS

    National Seminar on Opportunity in Medicinal Plant Research,Jadavpur University, Kolkata, India from 29th -30th November,

    2014National Symposium on Clinical Research, Good Clinical Practice,

    Pharmacovigilance, Newer Issues in Ethics, regulatory requirement

    in New Drug Applications and Clinical Trials, by CDRI, Lucknow,

    India from 3rdto 4thDecember, 2014

    International Conferences on Recent Advances in Nanoscience &Nanotechnology-2014 at JNU New Delhi, India from 15th to 16th

    December, 2014

    DRUGS UPDATES

    FDA Approves Hysingla ER - Extended-

    Release Hydrocodone with Abuse-Deterrent

    Properties: (20thNovember, 2014)The U.S. Food and Drug Administration today approved Hysingla

    ER (hydrocodone bitartrate), an extended-release (ER) opioidanalgesic to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternativetreatment options are inadequate.Read more

    CAMPUS NEWS

    Congratulation to Rupam Saha, student of M.Pharm 2ndyear, who

    got 1stprize for the poster presentation in the National seminar on

    Control of Viral Menace using Delivery Design organised by Dr.

    B.C.Roy College of Pharmacy & AHS in association with IPA

    Bengal Branch.

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    http://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://www.drugs.com/newdrugs/fda-approves-hysingla-er-extended-release-hydrocodone-abuse-deterrent-properties-4112.htmlhttp://www.drugs.com/newdrugs/fda-approves-hysingla-er-extended-release-hydrocodone-abuse-deterrent-properties-4112.htmlhttp://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docx
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    On 14thand 15thNovember 2014 the Industrial visit of B.Pharm 2ndyear students was conducted in East India Pharmaceutical Works

    Limited, Kolkata under the supervision of Mr. Jaydip Roy, Mr.

    Debabrata Ghoshdastidar, Mr. Samrat Bose, Ms Jeentara Begum,Mr. Soumya Bhattacharya and Ms. Moumita Chowdhury.

    A Debate on Unity was held on 14thNovember 2014 and the jointwinner was Sreejit Roy , Bsc 2nd year and Pratik Nandi ,Bsc firstyear (Chairperson of debate: Dr Lopamudra Datta and Ms.Priyanka Ray).

    On 14th November, 2014 a Quiz competition was held on WorldDiabetes Day and the winner was Pratik Nandi and Sreyosi Dey,

    Bsc first year.Runner up Anirban Roy and Ankur Mondal B.Pharm third year

    (Quiz Master: Mr. Soumya Bhattacharya)

    A Seminar was held on 14th November 2014 World Diabetes Dayon Angiogenesis and Role of Amino Acids by Dr Debatosh Datta,

    Research scientist.

    GNIPST commemorated the 126th Birth Anniversary of Maulana

    Abul Kalam Azad on Tuesday, 11th November 2014.On 7thNovember 2014 the students of GNIPST participated in the

    Run for Unity as a mark of tribute to the efforts of the country'sfirst Home Minister Sardar Vallabhbhai Patel.

    Congratulation to the winner of Cricket Tournament-B.Pharm 3rdyear, 2014Runner up team-B.Sc and BHM, 2014

    Congratulation to the highest run scorer of Cricket Tournament-

    Tanmoy Das Biswas, B.Pharm 3rd year, 2014Congratulation to the highest wicket taker of Cricket

    Tournament-Subhodip Das, B.Pharm 3rd year, 2014

    Congratulation to the winner of Carom Tournament (Boys)-Sk. Abdul Salam, B.Pharm 2ndyear, 2014

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    http://economictimes.indiatimes.com/topic/Sardar%20Vallabhbhai%20Patelhttp://economictimes.indiatimes.com/topic/Sardar%20Vallabhbhai%20Patel
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    1st Runner up-Subhayan Dutta, M.Sc (Biotechnology Department)

    2nd year, 2014

    2nd Runner up-Nirupan Gupta, B.Pharm 1styear, 2014

    Congratulation to the winner of Carom Tournament (Girls)-Aishwarya Datta, B.Pharm 2ndyear, 20141st Runner up-Krishnakali Basu, B.Pharm 3rdyear, 2014

    2nd Runner up-Rituparna Das, B.Pharm 3rdyear, 2014

    Congratulation to the winner of Chess Tournament (Boys)-Basab Brata Dey, M.Sc (Biotechnology Department) 2ndyear, 20141st Runner up-Ankit Chowdhury, B.Pharm 1styear, 2014

    2nd Runner up-Smaranjeet Banik, B.Pharm 3rdyear, 2014

    Congratulation to the winner of Chess Tournament (Girls)-Rituparna Das, B.Pharm 3rdyear, 20141st Runner up-Varsa Srivastav, B.Sc(Bioptechnology Department)

    1styear, 2014

    2nd Runner up- Krishnakali Basu, B.Pharm 3rdyear, 2014

    The GNIPST Cricket Tournament, Carom Tournament and ChessTournament was held on 21stand 22nd October, 2014.

    The Cultural Programme on Bijoya Dashami and Kali Puja washeld on 20thOctober, 2014

    An exhibition on Photography and Painting was held on 20thOctober, 2014

    Congratulation to the winner of Football Tournament-B.Pharm3rd year, 2014

    Runner up team-B.Pharm final year, 2014

    Congratulation to the winner of Table Tennis Tournament-Krishnakali Basu, B.Pharm 3rd year, 20141st Runner up-Aindrila Bhowmick, B.Pharm 2nd year, 2014

    2nd Runner up-Sayani Banerjee, B.Pharm 2nd year, 2014

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    The GNIPST Football Tournament (for male students) and TableTennis tournament (for female students) was held on 25th and

    26th September, 2014.

    On 5th

    September, 2014 the students of GNIPST have arranged awonderful Teachers Day Programme. On behalf of all the teachers

    of GNIPST I would like to thank our beloved students.

    The Freshers welcome programme was held on 14thAugust, 2014.Welcome 1styear students.

    We congratulate the following M.Pharm. final year students whohave made their positions in different pharmaceutical companies.

    Anirban Banerjee (Emami Ltd.)Mahender Roy (Stadmed private Ltd.)

    We congratulate the following B.Pharm. final year students fortheir success.

    Samadrita Mukherjee (Abbott India Ltd.)

    Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)

    Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)

    Avishek Naskar (Glaxo SmithKline-Marketing)Bappaditya Manik (USV Limited)

    Sarbani Das (Nutri Synapzz-Marketing)

    Ankita Roy (Nutri Synapzz-Marketing)

    Rahul Mitra (B M Pharmaceuticals-Production)

    The following B.Pharm. final year students have qualified, GPAT-2014. We congratulate them all.

    Utsha Sinha

    Satarupa Bhattacharya

    Sandipan Sarkar

    Purbali Chakraborty

    Reminiscence, 2014(GNIPST Reunion) was held in Collegecampus on 2ndFebruary,2014.

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    Identify the place

    Answer of Previous Issues Image

    JawharLal Nehru

    Send your thoughts/

    Quiz/Puzzles/games/write-ups or any other

    contributions for Students Section

    answ ers of this Section at

    [email protected]

    EDITORS NOTE

    It is a great pleasure for me to publish the 3rd

    issue of 39th

    Volume

    of GNIPST BULLETIN. All the followers of GNIPST BULLETINare able to avail the bulletin through facebook account GNIPST

    bulletin I am very much thankful to all the GNIPST members and

    readers who are giving their valuable comments, encouragements

    and supports. I am also thankful to Dr. Abhijit Sengupta, Director

    of GNIPST for his valuable advice and encouragement. Special

    thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar

    and Mr. Soumya Bhattacharya for their kind co-operation and

    technical supports. Thank you Mr. Soumya Bhattacharyafor the

    questionnaires of the student section. An important part of the

    improvement of the bulletin is the contribution of the readers. You

    are invited to send in your write ups, notes, critiques or any kind of

    contribution for the forthcoming special and regular issue.

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    Director of JIS Group and Dr. Abhijit Sengupta, Director cum

    Principal of GNIPST with lamp lighting. The programme started

    with an opening song performed by the B.Pharm students of this

    institute. The seminar consists of a series of lectures, video

    presentations and poster session. On the pre lunch session 4

    lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata

    Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty

    respectively. On their presentation the speakers enlighten the

    recent development of Pharmacy, Genetics and Microbiology and

    their correlation with Life Sciences. On the post lunch session, Ms.

    Saini Setua and Ms. Sanchari Bhattacharjee explained the recent

    development and career opportunities in Biotechnology andHospital Management. The programme was concluded with

    valedictory session and certificate distribution.

    About 50 Higher secondary school teachers from different

    schools of Kolkata and North& South 24 Parganas district of West

    Bengal participated in this programme. A good interactive session

    between participants and speakers was observed in the seminar.

    The seminar was a great success with the effort of faculties, staffsand students of our Institute. It was a unique discussion platform

    for school teachers and professional of the emerging and newer

    branches of Life Science.

    The general body meeting of APTI, Bengal Branch has been

    conducted at GNIPST on 15thJune, 2012. The program started with

    a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural

    Products, JU on the skill to write a good manuscript forpublication in impact journals. It was followed by nearly two hour

    long discussion among more than thirty participants on different

    aspects of pharmacy education. Five nonmember participants

    applied for membership on that very day.

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    GNIPST is now approved by AICTE and affiliated to WBUT for

    conducting the two years post graduate course (M.Pharm)

    in PHARMACOLOGY.The approved number of seat is 18.

    The number of seats in B.Pharm. has been increased from 60 to120.

    AICTE has sanctioned a release of grant under Research

    Promotion Scheme (RPS) during the financial year 2012-13to

    GNIPST as per the details below:

    a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical

    Science & Technology.

    b.Principal Investigator:Dr. LopamudraDutta.

    c. Grant-in-aid sanctioned:Rs. 16,25000/- only

    d.Approved duration: 3 years

    e. Title of the project: Screening and identification of potential

    medicinal plant of Purulia & Bankura districts of West Bengal

    with respect to diseases such as diabetes, rheumatism, Jaundice,

    hypertension and developing biotechnological tools for enhancing

    bioactive molecules in these plants.

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