gnipst bulletin 26.1

7/28/2019 Gnipst Bulletin 26.1

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14th June, 2013 Volume No.: 26 Issue No.: 01

Contents Message from GNIPS

Letter to the Editor News Update

Health awareness

Disease Outbreak Ne

Forth Coming Events

Drugs Update

Campus News

Students Section

Editors Note

Archive

Vision

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

PHARMACEUTICAL AND BIOLOGICAL SCIENCE

EDITOR: Soumya BhattacharyaGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND

TECHNOLOGY

GNIPST Photo Gallery

For your comments/contributionOR

For Back-Issues,

mailto:[email protected]

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MESSAGE FROM GNIPSTGNIPST BULLETIN is the official publication of Guru Nanak

Institute of Pharmaceutical Science & Technology. All the

members of GNIPST are proud to publish the 26th Volume of

GNIPST BULLETIN. Over the last two years this bulletin

updating readers with different scientific, cultural or sports

activities of this prestigious institute and promoting knowledge of

recent development in Pharmaceutical and Biological Sciences.

Students section is informing readers about some curious facts of

drug discovery, science, sports and other relevant fields. We look

forward to seeing your submission and welcome comments and

ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

World Blood Donor Day,2013-Give the gift of

life: donate blood

As per WHO calender, World Blood Donor day is celebrated every

year on 14th June. The prime goal of this event is to raise of the need

for safe blood and blood products and to thank voluntary unpaid

blood donors for their life-saving gifts of blood. The theme of this

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years World Blood Donor Day is Give the gift of life: donate blood.

The first World Blood Donor Day was observed in 2004. Its

designation as an annual global event by the Fifty-eighth World

Health Assembly followed in 2005.10th edition of World blood donor

day will focus on the value of donated blood to the patient, not only in

saving life, but also in helping people live longer and more productive

lives.Read more

Body clocks link to Osteoarthritis

(11th June, 2013)

The group of researchers of University of Manchester established the

role of biological clock on cartilage tissue functioning using mice

model. This suggested that clock deterioration could contribute to an

increased risk of developing osteoarthritis in later life. According to

scientists scheduled exercise, regular meals and the periodic warming

and cooling of joints could be used to relieve the symptoms of

osteoarthritis.Read more

New surgical technique for Bell's Palsy Facial

Paralysis (11th June, 2013)

Electrical stimulation is used by Dr. J Leonetti, a surgeon of Loyola

University Medical Centre to stimulate nerves to treat the Bells Palsi.

Bell's palsy is a condition that causes paralysis on one side of a

patient's face. Leonetti said some patients who have received

http://www.who.int/campaigns/world-blood-donor-day/2013/en/index.htmlhttp://www.who.int/campaigns/world-blood-donor-day/2013/en/index.htmlhttp://www.who.int/campaigns/world-blood-donor-day/2013/en/index.htmlhttp://www.sciencedaily.com/releases/2013/06/130611204534.htmhttp://www.sciencedaily.com/releases/2013/06/130611204534.htmhttp://www.sciencedaily.com/releases/2013/06/130611204534.htmhttp://www.sciencedaily.com/releases/2013/06/130611204534.htmhttp://www.who.int/campaigns/world-blood-donor-day/2013/en/index.html


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electrical stimulation have seen muscle movement return to their face

after one or two months.Read more

Characterization of a Genetic Subtype ofAutism(11th June, 2013)

The first comprehensive and prospective study is carried by Seaver

Autism Center enrolled 32 autistic participants with SHANK3

deletions to comprehensively assess their clinical symptoms and

examine how the size of the SHANK3 deletion correlated to those

symptoms. The findings provide additional evidence of the significant

impairment associated with SHANK3 deficiency.Read more

New mechanism of TB Drug Resistance

Identified (12th June, 2013)

A recent study, led by researchers at the Johns Hopkins Bloomberg

School of Public Health and Huashan Hospital, Fudan University, has

identified a new mechanism for Pyrazinamide (PZA)-resistance,

which provides new insight into the how this mysterious drug works.

The study is available online June 12 in the journal Emerging Microbes &

Infections.Read more

Brain's 'Dark Side' as key toCocaine Addiction(12th June, 2013)

http://www.sciencedaily.com/releases/2013/06/130611204432.htmhttp://www.sciencedaily.com/releases/2013/06/130611204432.htmhttp://www.sciencedaily.com/releases/2013/06/130611204432.htmhttp://www.sciencedaily.com/releases/2013/06/130611154035.htmhttp://www.sciencedaily.com/releases/2013/06/130611154035.htmhttp://www.sciencedaily.com/releases/2013/06/130612132549.htmhttp://www.sciencedaily.com/releases/2013/06/130612132549.htmhttp://www.sciencedaily.com/releases/2013/06/130612132549.htmhttp://www.sciencedaily.com/releases/2013/06/130612132549.htmhttp://www.sciencedaily.com/releases/2013/06/130611154035.htmhttp://www.sciencedaily.com/releases/2013/06/130611204432.htm


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In experiments with rats, The Scripps Research Institute (TSRI

)researchers found signs that cocaine-induced changes in this brain

system contribute to anxiety-like behavior and other unpleasant

symptoms of drug withdrawal -- symptoms that typically drive an

addict to keep using. When the researchers blocked specific brain

receptors called kappa opioid receptors in this key anxiety-mediating

brain region, the rats' signs of addiction abated.Read more

Breakthrough allows fast, reliable pathogenidentification(12th June, 2013)

A University of Toronto team including researchers from Electrical

and Computer Engineering and the Institute of Biomaterials &

Biomedical Engineering has created an electronic chip that can

analyze blood and other clinical samples for infectious bacteria with

record-breaking speed.Read more

New Sickle Cell Anemia Therapy advances to

Phase II Clinical Trials(12th June, 2013)

A group of researchers are preparing to launch Phase II of a clinical

trial to investigate a potential new therapy for reducing the disorder'sseverest symptoms. Sickle cell anemia is a serious, painful and chronic

illness that impedes blood flow and can lead to early death. The Phase

II trial, funded by National Institutes of Health, is testing an already

existing drug called Lexiscan.Read more

http://www.sciencedaily.com/releases/2013/06/130612144735.htmhttp://www.sciencedaily.com/releases/2013/06/130612144735.htmhttp://www.sciencedaily.com/releases/2013/06/130612133359.htmhttp://www.sciencedaily.com/releases/2013/06/130612133359.htmhttp://www.sciencedaily.com/releases/2013/06/130612092953.htmhttp://www.sciencedaily.com/releases/2013/06/130612092953.htmhttp://www.sciencedaily.com/releases/2013/06/130612092953.htmhttp://www.sciencedaily.com/releases/2013/06/130612133359.htmhttp://www.sciencedaily.com/releases/2013/06/130612144735.htm


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New therapy target for Kids' Fever-Induced

Seizures(11th June, 2013)

A team of Northwestern Medicine researchers has identified a new

key factor in the generation of febrile seizures, leading to a new

therapeutic target for humans. The team found that nimodipine, a

commonly available L-type calcium-channel blocker, dramatically

reduced the incidence and duration of febrile seizures in animals.Read more

Experimental vaccine shows promise against TB

Meningitis (11th June, 2013)

A team of Johns Hopkins researchers working with animals has

developed a vaccine that prevents the virulent TB bacterium from

invading the brain and causing the highly lethal condition TB

meningitisRead more

HEALTH AWARENESS

Safe blood transfusion -a real gift for life

Blood donation and its safe transfusion are considered as the gift of

life. Every second, someone in the world needs blood. In every

country, surgery, trauma, severe anaemia and complications of

http://www.sciencedaily.com/releases/2013/06/130603163809.htmhttp://www.sciencedaily.com/releases/2013/06/130611204429.htmhttp://www.sciencedaily.com/releases/2013/06/130611204429.htmhttp://www.sciencedaily.com/releases/2013/06/130603163809.htm


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pregnancy are among the clinical conditions that demand blood

transfusion. According to Melbourne Declaration, World Health

Organization and other international policymaker recognize that

Safe blood and blood products and their transfusion are a critical

aspect of health care and public health that saves millions of lives

and improves the health and quality of life of many patients.

The importance of protecting donors welfare and appreciating

their generous donations of the gift of life.

The realization of the health related Millennium DevelopmentGoals to reduce child mortality (Goal 4), to improve maternal

health (Goal 5) and to combat HIV/AIDS, malaria and other

diseases (Goal 6) is dependent on universal access to safe blood

transfusion.

Regular voluntary, non-remunerated blood donors are the

cornerstone of a safe and sustainable national supply of blood and

blood products sufficient to meet the transfusion requirements of

the patient population.

However two major problems related to blood transfusion are

blood shortage andunsafe blood.

Many patients do not have access to blood when they need it.

Of the estimated 80 million units of blood donated annually

worldwide, only 38% are collected in the developing world where

82% of the worlds population live. The shortfall has a particular



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impact on women with complications of pregnancy, trauma victims

and children with severe life-threatening anaemia. Up to 150 000

pregnancy-related deaths could be avoided each year through access

to safe blood.

Another problem is unsafe blood. Many people are exposed to

avoidable, life-threatening risks through the transfusion of unsafe

blood. It is estimated that about 5% of HIV infections are transmitted

by unsafe transfusion as a result of the collection of blood from unsafe

donors, irregular or inadequate supplies of materials to test blood forinfections, poor laboratory testing procedures, inadequately trained

staff and absence of quality systems or unnecessary transfusions.

Blood is also an effective means of transmitting hepatitis B, hepatitis

C, syphilis, malaria and Chagas disease. Less accessibility of safe

blood is the major contribution to the load of HIB patient and

mortality of the African and other developing countries.

The keys of safe blood transfusion:

The major ways to ensure the safe blood transfusion are:

recruitment of low-risk blood donors,

testing

blood grouping,

processing into components

storage and transportation



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According to WHO, a safe and adequate blood supply is not only

an essential human right but also a cost-effective investment in the

health and economic wealth of every nation.

WHO strategy for blood safety:

A well-organized, nationally-coordinated blood transfusion service

that can provide adequate and timely supplies of safe blood for all

patients in need.

The collection of blood only from voluntary non-remuneratedblood donors from low-risk populations.

Testing of all donated blood for transfusion-transmissible

infections, blood grouping and compatibility testing.

The appropriate clinical use of blood, including the use of

alternatives to transfusion wherever possible, and the safe

administration of blood and blood products.

Quality system covering all stages of the transfusion process.

Key messages - World Blood Donor Day 2013

A single unit of donated blood can save up to three lives.

Every year 107 million blood donations are collected worldwide.

Approximately half of these are collected in high-income countries,

home to only 15% of the worlds population.



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Many patients requiring transfusion, particularly in developing

countries, do not have timely access to safe blood.

Blood collection from voluntary non-remunerated blood donors is

the cornerstone of a safe and sufficient blood supply. Regular

voluntary blood donors are the safest source of blood, as there are

fewer bloodborne infections among these donors than among

people who donate for family members in emergencies or who give

blood for payment.

In low- and middle-income countries, the greatest use of donatedblood is for pregnancy-related complications and severe childhood

anaemia.

In high-income countries, transfusion is most commonly used for

supportive care in heart surgery, transplant surgery, massive

trauma and cancer therapy.

Providing safe and adequate blood through well-organized,

national blood systems should be an integral part of every countrys

national health-care policy.

WHOs goal is for all countries to obtain all their blood supplies

from 100% voluntary unpaid donors by 2020.

WHO provides policy guidance and technical assistance to

support countries to ensure that safe blood and blood products are

available and used appropriately for all people who need them.



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DISEASE OUTBREAK NEWS

Middle East respiratory syndrome corona virus

(MERS-CoV)(7thJune, 2013)

The Ministry of Health in Saudi Arabia has notified WHO of an

additional laboratory-confirmed case with Middle East respiratory

syndrome coronavirus (MERS-CoV).The patient is a 83-year-old man

with underlying medical conditions, who became ill on 27 May 2013

and died on 31 May 2013. He is from Al-Ahsa, where an outbreak

began in a health care facility since April 2013.Read more

Meningococcal disease: 2013 epidemic season in

the African Meningitis Belt (6th

June, 2013)From 1 January to 12 May 2013 (epidemiologic week 19), 9249

suspected cases of meningitis, including 857 deaths, with a case

fatality ratio of 9.3 percent, have been reported from 18 of the 19

African countries under enhanced surveillance for meningitis. Read

more

http://www.who.int/csr/don/2013_06_01_ncov/en/index.htmlhttp://www.who.int/csr/don/2013_06_01_ncov/en/index.htmlhttp://www.who.int/csr/don/2013_06_03/en/index.htmlhttp://www.who.int/csr/don/2013_06_03/en/index.htmlhttp://www.who.int/csr/don/2013_06_03/en/index.htmlhttp://www.who.int/csr/don/2013_06_03/en/index.htmlhttp://www.who.int/csr/don/2013_06_03/en/index.htmlhttp://www.who.int/csr/don/2013_06_01_ncov/en/index.html


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FORTHCOMING EVENTS

Two short-term (2 weeks each) AICTE-sponsored refresher

courses on: Innovation and excellence in Pharmaceutical Sciences for

teaching staffs of the Indian Universities and colleges in QIP Nodal

Cell (Pharmacy), Department of Pharmaceutical Technology,

Jadavpur University, Kolkata-700 032 from 2nd July to 29th

July,2013.Read more

AICTE Sponsored Quality Improvement Programme onProduction to Prescription - Opportunities for Innovation on

MCOPS, Manipal University from 1-13th July, 2013.Read more

DRUGS UPDATES

FDA approves Xgevato treat giant cell tumor of

the bone (13 June, 2013)

The U.S. Food and Drug Administration today expanded the

approved use of Xgeva (denosumab) to treat adults and some

adolescents with giant cell tumor of the bone (GCTB), a rare and

usually non-cancerous tumor.Read more

http://www.jaduniv.edu.in/upload_files/asc_info/1368622884-1.pdfhttp://www.jaduniv.edu.in/upload_files/asc_info/1368622884-1.pdfhttp://www.manipal.edu/Institutions/Pharmacy/MCOPSManipal/Documents/events/QIP%20on%20Production%20to%20Prescription-%20Opportunities%20for%20Innovation.pdfhttp://www.manipal.edu/Institutions/Pharmacy/MCOPSManipal/Documents/events/QIP%20on%20Production%20to%20Prescription-%20Opportunities%20for%20Innovation.pdfhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm356528.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm356528.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm356528.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm356528.htmhttp://www.manipal.edu/Institutions/Pharmacy/MCOPSManipal/Documents/events/QIP%20on%20Production%20to%20Prescription-%20Opportunities%20for%20Innovation.pdfhttp://www.jaduniv.edu.in/upload_files/asc_info/1368622884-1.pdf


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FDA approves two drugs, companion diagnostic

test for advanced skin cancer(29 May 2013)The U.S. FDA approved two new drugs, Tafinlar (dabrafenib) and

Mekinist (trametinib), for patients with advanced (metastatic) or

unresectable (cannot be removed by surgery) melanoma, the most

dangerous type of skin cancer.Read more

CAMPUS NEWS

The following B.Pharm. final year students have qualified, GPAT-

2013. We congratulate them all.

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http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm354199.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm354199.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm354199.htm


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STUDENTS SECTION

WHO CAN ANSWER FIRST???

Which famous tennis player was infected with

HIV infection during a blood transfusion in

1983 ?

Which Physicians birthday is celebrated as

World Blood Donor Day?Answer of Previous Issue Question:

A)Medical stent B)Lysergic acid diethylamide(LSD)

Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for Students Section

& answers of this Section [email protected] NOTE

I am proud to publish the 1st issue of 26th Volume of GNIPST

BULLETIN. On behalf of entire GNIPST members, contributors and

the valuable readers of GNIPST BULLETIN I want to thank Mr.

Debabrata Ghosh Dastidar who edited the bulletin last one year

with excellence.

mailto:[email protected]:[email protected]:[email protected]


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GNIPST BULLETIN now connected globally through facebook

account GNIPST bulletin

I want to convey my thanks to all the GNIPST members and the

readers for their valuable comments, encouragement& supports.

I am thankful to Dr. Abhijit Sengupta, Director of GNIPST and

Prof. Dipankar Chakraborty, Registrar of GNIPST for their

valuable advice and encouragement. Special thanks to Dr. Prerona

Saha and Mr. Debabrata Ghosh Dastidar for their kind co-

operation and technical supports.

An important part of the improvement of the bulletin is the

contribution of the readers. You are invited to send in your write ups,

notes, critiques or any kind of contribution for the forthcoming

special and regular issue.

ARCHIVE

The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15th June, 2012. The program started

with a nice presentation by Dr. Pulok Kr. Mukherjee, School of

Natural Products, JU on the skill to write a good manuscript for

publication in impact journals. It was followed by nearly two hour

long discussion among more than thirty participants on different

aspects of pharmacy education. Five nonmember participants

applied for membership on that very day.



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GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years post graduate course (M.Pharm) in

PHARMACOLOGY. The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to

120.

2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),

Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and

Dosimetry (SWC-2013) : On the Way to Personalized Medicine

Dates 28 Feb 2013 02 Mar 2013

Location: Chandigarh, India.Details.

AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-

13to GNIPST as per the details below:

a. Beneficiary Institution: Guru Nanak Institution of

Pharmaceutical Science & Technology.

b.Principal Investigator: Dr. Lopamudra Dutta.

c. Grant-in-aid sanctioned :Rs. 16,25000/- only

d.Approved duration: 3 years

e. Title of the project: Screening and identification of potential

medicinal plant of Purulia& Bankura districts of West Bengal

with respect to diseases such as diabetes, rheumatism, Jaundice,

http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/


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hypertension and developing biotechnological tools for enhancing

bioactive molecules in these plants.

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