GLP-1 Receptor Agonists: How Early Is Appropriate?

Goals

Differentiation of GLP-1-RAs

Antihyperglycemic Therapy in Type 2 Diabetes: General Recommendations

Potential Clinical Advantagesof GLP-1 Receptor Agonists

Physiologic Effects of GLP-1 Receptor Agonists

Potential for GLP-1 RAs as First-Line Therapy

Choosing Between Agents With Low Rates of Hypoglycemia

Potential Clinical Disadvantagesof GLP-1 Receptor Agonists

Potential of Once-Weekly GLP-1 Receptor Agonists: Exenatide

QW

Combining Basal Insulin With a GLP-1 Receptor Agonist

Fixed Formulation

Once-Weekly GLP-1 RA in Combination With Basal Insulin*

Novel Emerging Strategies

Safety – Patient Education

Closing Comments

Abbreviations

References

References (cont)

References (cont)

References (cont)