Pipeline drug

A drug pipeline is the set of compounds (ie drugs in development) that a pharmaceutical company has under development at any given point in time.

The development of drugs involves various phases that can broadly be grouped in 3 stages: pre-clinical, clinical trials and marketing (or post-approval). Pharmaceutical companies usually have a number of compounds in their pipelines.

The drug pipeline is an important indicator of the value and future prospects of a company. Usually the more compounds in the pipeline, and the more advanced stage that these are in the better.

Other factors that are taken into account when assessing the value of a pipeline include the size of the target market of each drug, the market share that the drug is expected to capture and the risk that it will not be approved.

The cost of developing a new drug is astronomical – typically a drug costs many hundreds of millions and can reach 1 billion dollars over 15-17 years. Assessing this risk and filtering out as early as possible compounds that may not eventually get approved is essential to the pharmaceutical industry and involves checking the effectiveness of drugs as well as the likelihood of toxic events (Adverse event prediction).

La palabra pipeline se usa en el mundo empresarial para indicar que un producto todavía no está disponible, pero lo estará en breve. Puede traducirse, según el contexto, como ‘estar en fase de desarrollo’, ‘estar en la fase de investigación’, ‘estar en proyecto’ o ‘estar tramitándose’. Cuando se encuentre la palabra pipeline sola, se puede traducir como ‘productos en fase de desarrollo’ o ‘cartera de productos en fase de desarrollo (ni debe confundirse con portafolio o product portafolio, que es la cartera de productos de la empresa, en el sentido de ‘cartera de productos comercializados’.

Standby Statement Declaración provisional

Holding Statement Declaración reactiva

In a crisis, it is always advisable to face the media as quickly as possible. As soon as sufficient information is available the committee should draft a reactive statement to tackle initial inquiries known as a holding statement, this is sent to journalists on request only and is designed to give basic information about an incident and is crucial to ensure journalists have the right facts. If the media takes the words of by standers or other third party sources there is a danger of exaggeration or misinformation that could compound the problem.

Keyhole limpet hemocyanin

A substance taken from a marine organism that may be linked to a specific antigen to boost the immune response to that antigen. Keyhole limpet hemocyanin is being studied as a way to increase the immune response to cancer vaccines. It is a type of immune modulator. Also called KLH.

Hemocianina extraída del molusco llamado lapa californiana

Sustancia que se obtiene de un organismo marino que se puede vincular con un antígeno específico para estimular la respuesta inmunitaria a ese antígeno. La hemocianina de lapa californiana está en estudio como una forma de aumentar la respuesta inmunitaria a las vacunas contra el cáncer. Es un tipo de inmunomodulador. También se llama KLH.

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