global challenges in cancer pain s. lawrence librach md,ccfp,fcfp professor, department of family...
TRANSCRIPT
![Page 1: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/1.jpg)
Global Challenges in Cancer Pain
S. Lawrence Librach MD,CCFP,FCFPProfessor, Department of Family & Community Medicine
Sun Life Financial Chair & Director, Joint Centre for Bioethics, University of Toronto
Cancer Pain Physician, Princess Margaret Hospital, Toronto
![Page 2: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/2.jpg)
Objectives
1. Cancer pain management as a human right2. Relationship with industry & pain
![Page 3: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/3.jpg)
Pain Management as a Human Right
• IASP Montreal DeclarationDeclaration that access to pain management is a
fundamental human rightMeans that there is an ethical & probably legal
requirement to act
![Page 4: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/4.jpg)
IASP Montreal Declaration
• Pain management is inadequate in most of the world because of:Inadequate access to treatment Failure to recognize that chronic pain is a serious
chronic health problem
![Page 5: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/5.jpg)
IASP Montreal Declaration
• Pain management is inadequate in most of the world because of:Major deficits in knowledge of health care
professionals regarding the mechanisms & management of pain
Chronic pain with or without diagnosis is highly stigmatized
![Page 6: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/6.jpg)
IASP Montreal Declaration
• Pain management inadequate in most of the world because: Most countries have no national policy at all or
very inadequate policies regarding the management of pain as a health problem, including an inadequate level of research & education
Pain Medicine is not recognized as a distinct specialty with a unique body of knowledge & defined scope of practice founded on research & comprehensive training programs
![Page 7: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/7.jpg)
IASP Montreal Declaration
• Pain management is inadequate in most of the world because:World Health Organization (WHO) estimates that
5 billion people live in countries with low or no access to controlled medicines and have no or insufficient access to treatment for moderate to severe pain
There are severe restrictions on the availability of opioids & other essential medications, critical to the management of pain
![Page 8: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/8.jpg)
Pain Management as a Human Right
• Human Rights Watch www.hrw.org Global State of Pain
Treatment & Access to Palliative Care as a Human Right
![Page 9: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/9.jpg)
Pain Management as a Human Right-HRW
• Every year, tens of millions of people around the world with life-threatening illnesses suffer unnecessarily from severe pain and other debilitating symptoms because they lack access to palliative care, an inexpensive health service that aims to improve the quality of life of people with serious health conditions
![Page 10: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/10.jpg)
![Page 11: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/11.jpg)
![Page 12: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/12.jpg)
• In Central America and the Caribbean, about half of the countries consume so few opioid medications that even if all were used exclusively to treat patients with terminal cancer and HIV for pain, less than a third of them could receive adequate treatment (Belize, El Salvador, Honduras, Nicaragua, Saint Kitts and Nevis, Trinidad and Tobago, Jamaica, Dominican Republic, and Haiti)
![Page 13: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/13.jpg)
**T&T has 1/20 the population of Canada
![Page 14: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/14.jpg)
![Page 15: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/15.jpg)
INCB Report
• Need to achieve a balance between ensuring availability of internationally controlled substances for medical and scientific purposes and preventing their diversion and abuse
![Page 16: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/16.jpg)
INCB Report
• The Board considers all levels of consumption of narcotic drugs below 200 S-DDD per million inhabitants per day inadequate. However, this does not imply that levels above 200 S-DDD can be considered adequate as the determination of whether availability of internationally controlled substances required for treatment is sufficient depends on the specific morbidity data
![Page 17: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/17.jpg)
![Page 18: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/18.jpg)
![Page 19: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/19.jpg)
![Page 20: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/20.jpg)
Websites
• www.stoptortureinhealthcare.orgMultiple videos & reports
• www.treatthepain.comVideo “Life Before Death”
• http://www.incb.org/documents/Publications/AnnualReports/AR10_Supp_E.pdf
![Page 21: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/21.jpg)
PAIN AND INDUSTRY: ETHICS
![Page 22: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/22.jpg)
How to dance with porcupines: rules and guidelines ondoctors’ relations with drug companies BMJ 2003
• How to dance with porcupines: rules and guidelines on
• doctors’ relations with drug companies
![Page 23: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/23.jpg)
Pharmaceutical Industry & Opioid Availability
• Expensive sustained-release opioids seem to be making an appearance on formularies when cheaper alternatives like immediate- release & injectable morphine & hydromorphone are not allowed or in very limited supply in many countriesSometimes companies abandon markets
![Page 24: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/24.jpg)
Influence of Pharmaceutical Industry on Pain Professionals
• Clinical research funding in pain to a great extent funded by industry
• Conference support by industry is absolutely necessary for those conferences to take placeGlossy booths for industry
• Speakers bureaus & consultant contracts
![Page 25: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/25.jpg)
Influence of Pharmaceutical Industry on Pain Professionals
• Articles mostly funded by industry & many ghostwritten
• Research often multicentric & may be in jurisdictions where research ethics boards or independent boards have lower standards
• Data not made available to researchers
![Page 26: Global Challenges in Cancer Pain S. Lawrence Librach MD,CCFP,FCFP Professor, Department of Family & Community Medicine Sun Life Financial Chair & Director,](https://reader035.vdocuments.mx/reader035/viewer/2022062422/56649f1e5503460f94c35692/html5/thumbnails/26.jpg)
Summary
• There is much to do in relieving cancer pain• Pain relief is a human right• Availability of opioids around the globe is an
issue• The availability of opioids in T&T is very
limited & needed drugs are all generic