ginseng and colon cancer (1)
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Ginseng and Colon Cancer
Eugene Fung
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Where is Colon Located? The colon is the last part of the
digestive system in most vertebrates The colon extracts water and salt from
solid wastes before they are eliminated from the body
The site in which largely bacterial fermentation of unabsorbed material occurs
The colon absorbs water, potassium and some fat soluble vitamins
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The Colon: Morphology
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The Colon
The colon, cecum, and rectum make up the large intestine
In mammals, the colon consists of four sections:
(1) The ascending colon (2) The transverse colon (3) The descending colon (4) The sigmoid colon
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Colon Cancer Colon, or colorectal, cancer is cancer
that starts in the large intestine (colon) or the rectum (end of the colon)
The rectum is the end of the colon adjacent to the anus
Together, they form a long, muscular tube called the large intestine
Tumors of the colon and rectum are growths arising from the inner wall of the large intestine
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Symptoms
Blood in the stool Diarrhea, constipation, or other
change in bowel habits Narrow stools Weight loss with no known reason
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Stages of Colon Cancer Stage 0: Very early cancer on the
innermost layer of the intestine Stage I: Cancer is in the inner layers of
the colon Stage II: Cancer has spread through the
muscle wall of the colon Stage III: Cancer has spread to the
lymph nodes Stage IV: Cancer has spread to other
organs
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Colon Cancer and Polyp
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Benign Polyps (1) Benign tumors of the large intestine are
called polyps Malignant tumors of the large intestine
are called cancers Benign polyps do not invade nearby
tissue or spread to other parts of the body Benign polyps can be easily removed
during colonoscopy and are not life-threatening
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Benign Polyps (2) If benign polyps are not removed
from the large intestine, they can become malignant (cancerous) over time
Most of the cancers of the large intestine are believed to have developed from polyps
?? Most polyps are developed from “what you eat”
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Early Detection
According to the American Cancer Society, colorectal cancer is one of the leading causes of cancer-related deaths in the United States
However, early diagnosis often leads to a better cure.
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Exams and Tests
(1) A fecal occult blood test (FOBT) may detect small amounts of blood in the stool
However, this test is often negative in patients with colon cancer
It is also important to note that a positive FOBT doesn't necessarily mean you have cancer
(2) Colonoscopy(3) Sigmoidoscopy
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Blood Tests Measurement of the patient's blood for
elevated levels of certain proteins can give an indication of tumor load
High levels of carcinoembryonic antigen (CEA) in the blood can indicate metastasis of adenocarcinoma
These tests are frequently false positive or false negative
They are not recommended for screening It can be useful to assess disease
recurrence
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Higher Risks for Colon Cancer (1)
Age older than 60 African American of eastern European descent Eat a diet high in red or processed meats Have cancer elsewhere in the body Have colorectal polyps Have inflammatory bowel disease (
Crohn's disease or ulcerative colitis) Have a family history of colon cancer Have a personal history of breast cancer
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Higher Risks for Colon Cancer (2)
What you eat may play a role in your risk of colon cancer
Colon cancer may be associated with a high-fat, low-fiber diet and red meat
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Certain Genetic Syndromes
(1) Familial Polyp history (2) History of Hereditary
nonpolyposis colorectal cancer
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Treatments : The Big Three
Surgery (most often a colectomy) to remove cancer cells
Chemotherapy to kill cancer cells Radiation therapy to destroy
cancerous tissue
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Prevention is Better than Cure Cancer of the colon and rectum (also
referred to as colorectal cancer) can invade and damage adjacent tissues and organs
The spread of colon cancer to distant organs is called metastasis of the colon cancer
Once metastasis has occurred in colorectal cancer, a complete cure of the cancer is unlikely
“Prevention is better than Cure”
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Prevention
The death rate for colon cancer has dropped in the last 15 years
This may be due to increased awareness and screening by colonoscopy
Colon cancer can almost always be caught by colonoscopy in its earliest and most curable stages
Almost all men and women age 50 and older should have a colon cancer screening
Patients at risk may need earlier screening
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NSAIDs (Non-steroidal Anti-inflammatory Drugs) Some studies have reported that NSAIDs
(aspirin, ibuprofen, naproxen) may help reduce the risk of colorectal cancer
However, these medicines can increase your risk for bleeding and heart problems
Most experts do not recommend that most people take these medicines to prevent colon cancer
Talk to your health care provider about this issue.
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Change your Diet and Lifestyle
Changing your diet and lifestyle is important
Some evidence suggests that low-fat and high-fiber diets may reduce your risk of colon cancer
Dietary supplements, e.g. Ginseng
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Ginseng for Colon Cancer Maintenance
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Ginseng for Colorectal Cancer Colorectal cancer is one of the most
common types of cancer in the United States, and among the deadliest
Half of patients diagnosed with colorectal cancer eventually die from the disease
Less than 10 percent of patients with colorectal cancer that has spread will survive more than five years after diagnosis.
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Drawbacks of the Existing Treatments Because chemotherapy and other standard
treatments aren’t always effective and may have serious side effects, many patients have turned to herbal remedies.
Ginseng has been a staple of Asian herbal medicine, and studies have indicated that it might help not only prevent cancer, but also relieve some of the side effects (such as nausea and vomiting) of cancer therapies.
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Ginseng Study (1) Responsible for the herb’s anti-cancer properties Asian ginseng has a long history of use and research American ginseng has not been as well studied Last year researchers at The University of Chicago
launched a $6 million effort funded by the National Institutes of Health to investigate the anti-cancer potential of American ginseng
As part of that study, the researchers treated human colorectal cancer cells with extracts of American ginseng berry and root that had been steam heated.
The steamed extracts increased the saponin activity, and halted the cancer cells’ growth by as much as 99%
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Ginseng Study (2) Although treatment with ginseng doesn’t work
as well as chemotherapy, it might be an effective adjuvant cancer treatment, says study author Chun-Su Yuan, MD, PhD, Director of the Tang Center for Herbal Medicine Research at The University of Chicago
“It could be used together with chemotherapy to increase its efficacy and also to reduce the chemotherapy side effects,” he says. “It possibly could be a single compound that could be a new-generation cancer drug.”
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Ginseng Study (3) Although ginseng doesn’t have any noticeable
adverse effects in moderate doses, when given in larger amounts patients have noted increased heart rate, nausea, headaches, and difficulty sleeping, among other symptoms.
The challenge is to determine the optimal dose, and figure out how to deliver ginseng in the most effective way to target the cancer cells without causing significant side effects.
Future research should help resolve these issues. “We would like to start human trials in the future,” Dr. Yuan says. “Our initial results were promising.”
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Ginseng Study (4) Currently researchers are only in the
animal testing phase, and Dr. Yuan does not recommend that patients take ginseng supplements for cancer prevention or treatment.
Ginseng hasn’t yet been studied well enough for this purpose, and there is no guarantee that the active components Dr. Yuan’s team identified in the study will be in any given bottle of supplements.
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Ginseng Studied as Colorectal Cancer Fighter
Researchers have discovered that ginseng may be very effective against colorectal cancer
It depends on the nature of the ginseng preparation
Different preparation gives rise to different results to the body
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Bing Han Ginseng
Not Drug, nor Medicine It’s a dietary supplement Cannot cure any diseases Cannot cure cancers, e.g.
colorectal cancers
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Dietary Supplement Also known as food supplement or
nutritional supplement A preparation intended to supplement the diet
and provide nutrients, such as vitamins, minerals, fiber, fatty acids, or amino acids, that may be missing or may not be consumed in sufficient quantities in a person's diet
Some countries define dietary supplements as foods, while in others they are defined as drugs or natural health products
BH Ginseng: Natural Product Number (NPN80012575)
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Bing Han Ginseng as A Dietary Supplement
Rejuvenation Detoxification Normalizing body functions
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How to take BH Ginseng for Patients with Colorectal Cancer
Mix and match with powder and capsule Start with 4 flat scoops BH Powder and 2
BH Capsules every 2 hours with 200 ml of lukewarm water
Double the above amount after 2 days And double the latter amount after 3 days Check with your sponsor for more
information Bring them to this Webinar