GI System: Esophagus & StomachLaboratory Orientation

#126 H&E Mid-esophagus

Muscularis Externa

Skeletal muscle

Mixed smooth and skeletal muscle Submucosal

sero-mucous gland

Muscularis mucosae

Lamina propria

#126 Esophagus Also #153

Muscularis mucose

Submucosal gland

Muscularis Externa of mid-esophagus (#126):Skeletal and smooth m.

Muscularis Externa of lower esophagus (#155): Smooth muscle only

#155: Cardiac StomachCardio-esophageal junction (arrow)

Cardiac glands

#156: Fundic Stomach

Rugae

Mucosa of the Fundic Stomach

Lymphatic nodule

Muscularis mucosae

#156, #157: Gastric glands

Gastric pit lined by surface mucous cells

Mucous neck cells

Fundus or body

#157: Body of the gastric glands

#157: Base of the gastric glands

Chief cells

Parietal cells

#162 Pylolic StomachPylo-duodenal junction (arrow)

Pyloric sphincter muscle

Duodenum

Cardiac glands: coiled (mucous) glands pit:gland=1:1

Fundic (gastric) glands: straight glands pit:gland=1:5

Pyloric glands: coiled (mucous) glands pit:gland=2~3:1

GI System: Small and Large Intestine Laboratory Orientation

#29 Small Intestine

Mesentery (ct + epithelium)

Submucosa (connective tissue)

Mucosa (epithelium + lamina propria)

Muscularis Externa (smooth muscle)

LumenMuscularis mucosae

#29 – Intestinal Villi

Intestinal villi

#29-Simple columnar epithelium with striated border (microvilli) and goblet cells

Microvilli (striated border)

Goblet cells

Enterocytes?

#162 Pylo-duodenal junction (arrow)

Pyloric sphincter muscle

#161 Pylo-duodenal Junction and Pancreas

Pyloric stomach

Duodenum

Pancreas

Duodenum

Pancreas

Pyloric stomach

#161

Muscularis mucosae

Lymphatic nodules

Brunner’s gland

#161, 162 Duodenum

Lumen

Intestinal villus

Muscularis mucosaecrypts or i. glands

Brunner’s glands pancreas

#29, 168 Jejunum or Ileum

lumen

submucosa

Muscularis mucosae

Crypts of Lieberkuhn

#29, Intestinal glands (crypts)

Paneth cells

Enteroendocrine cells

Mitotic cell

? ?

?

#246

UCSF

Enteroendocrine cell

Paneth cell

#29, Myenteric (Auerbach’s) plexus

Ganglion cells

#176: Colon (Mucosa of the colon)

m.m

No villi, Straight glands, lots of goblet cells

#176 – colon

mucosa

#177-1, 177-3, 177-2 Recto-anal junction

Hemorrhoidal veins

Muscularis mucosae

Type of epithelium changesMuscularis mucosae fraysDilated veins