GET TO KNOW OUR COMPANY

CEO: Andrew Witty

Headquarters: Brentford, England

Founded: January 1st, 2001

Specialty: Prescriptions, Vaccines, Over-the-counter medicine

On January 1st, 2001, GlaxoWellcome plc and SmithKline Beecham plc, merged into what is now the second largest pharmaceutical firm in the world, GlaxoSmithKline. Currently, in 2014, we service over 50 prescription products spanning nine areas of therapeutic medicine. Each year, the company brings in sales volumes of $40 billion and dedicates $5 billion to the annual research budget.

MISSION STATEMENT

We have a challenging and inspiring mission: to improve the quality of human life by enabling people to do more, feel better, live longer. This mission gives us the purpose to develop innovative medicines and products and make them available to as many people who need them as possible.

We put our values of patient-focus, transparency, integrity and respect for people at the heart of every decision we make. We are focused on integrating these values into our culture, decision-making and how we work. We continue to review and challenge our practices to ensure that our actions meet or exceed the expectations of society.

PRODUCTS

• Prescriptions

• Vaccines

• Over-the-counter

RESEARCH FACILITIES

• Boston, Massachusetts

• Upper Merion, Pennsylvania

• Upper Province, Pennsylvania

We release the results of all our clinical research, regardless of whether the results are perceived to be positive or negative for our medicines.

Our Global Safety Board (GSB) makes decisions on product safety issues. The board continues to test the safety of products even after they have gone to market.

OUR WORK WITH COMMUNITIES

School District of Philadelphia

GlaxoSmithKline provided funding for the implementation of the SDP’s Preparing Scientifically Literate Students Initiative during the 2010-2011 academic year. GSK’s grant will provide 20 professional development sessions for approximately 120 science teachers.

Science in the Summer™

Science in the Summer™ is a free library program that has been funded solely by GSK since 1986 in Greater Philadelphia, PA, Pittsburgh, PA, and Research Triangle Park, NC.

NICORETTE STOP SMOKING AID

• Available in different dosages (2mg and 4mg)

• Child-proof packaging

• Sized for 12 week treatment period

• Comes with instructions

• Sugarless

• Formulated to minimize stickiness

• Comes in four flavors

Mint Fresh Mint Citrus Original

BENEFIT OF OTC DRUGS – ACCORDING TO FDA

OTC drugs generally have these characteristics:

• Their benefits outweigh their risks

• The potential for misuse and abuse is low

• Consumer can use them for self-diagnosed conditions

• They can be adequately labeled

• Health practitioners are not needed for the safe and effective use of the product

FDA DRUG DETAILS

Drug Details

Drug Name(s) NICORETTEFDA Application No. (NDA) 018612Active Ingredient(s) NICOTINE POLACRILEXCompany GLAXOSMITHKLINE

Original Approval or Tentative Approval Date

January 13, 1984

Chemical Type1 New molecular entity (NME)

Review Classification P Priority review drug

SAFETY

Nicorette and NicoDerm CQ have been found to have a well-established safety profile in 56 clinical trials over the past 25 years. Most recently, the FDA has concluded that there are no significant safety concerns with using Nicorette or NicoDerm CQ and a cigarette together. That’s why you can start using these products even if you aren’t immediately able to stop smoking and why you can — and should — keep using the product after a slip-up.

25+ YEARS OF FDA SUPPORT56 SAFETY AND EFFICACY STUDIES PERFORMED

7.66 MILLION PEOPLE QUIT IN THE U.S.

QUITTER CLINIC CASE

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Improvement in Patient Success Rate

CONT.

THE AVERAGE COST OF ONE PACK OF CIGARETTES IN FLORIDA TODAY IS $6.29

½ Pack / Day 1 Pack / Day 2 Packs / Day

Daily Cost $3.15 $6.29 $12.58

Weekly Cost $22.02 $44.03 $100.64

Monthly Cost $94.50 $188.70 $377.40

Yearly Cost $1,134.00 $2,264.40 $4,528.80

COST TO USE NICORETTE

At least At most

First 2 Weeks 140 280

Second 2 Weeks 112 210

Month 2 120 300

Month 3 60 150

Total Pieces 432 940

Total Cost to Quit $250.00 $556.00

TESTIMONIAL

“I had smoked for 35 years, average of 1 to 2 packs a day. I have tried the medications, the patch, gums, etc., many times through the years. Finally, a couple of years ago a friend offered me the Commit lozenges. I really wanted to quit this time, so I tried them. I was able to give up smoking. But, I continued to crave so I bought the gum and have alternated between the gum and lozenges every since. I don't want to go back to smoking and have yet to find anything that says how bad it is to continue the gum, so as long as I am not smoking and still want a cigarette every now and then, I will continue to chew the gum, as needed.”

- Anonymous

TESTIMONIALS

“Works real well. I have been smoke- free for 8 months. Definitely recommended if you are serious about quitting.”

-B. Michaels

“I was able to quit smoking with this gum. I was 2-pack/day smoker for 40+ years and found the gum tastes good and the nicotine was enough to take the edge off those cravings. I had tried several other methods to quit, but the gum was the only one that worked. I'm happily a non-smoker now.”

-Timmy Smith

TESTIMONIALS

“I decided to give the Nicorette 4mg Gum a try after reading the Amazon review by A. Creech "Kitchen Collector." It's been 9 weeks into the 12-week program and I haven't had a cigarette since. More importantly, I haven't had the cravings either.”

- Alex Honda

“I'm an ex-smoker. The mint gum is particularly pleasing and I do use it as a fall back when overcome by the urge to smoke. Rarely now. But I would not want to be without this item.”

- Evan Maddox

DOSAGE OPTIONS

If you smoke your first cigarette within 30 minutes of waking up, use the 4 mg strength.

If you smoke your first cigarette more than 30 minutes after waking up, use the 2 mg strength.

HOW IT WORKS

When you chew Nicorette Gum or suck on a Nicorette Lozenge or mini Lozenge, a low level of nicotine is absorbed through the lining of your mouth to help relieve cravings. By helping to reduce your nicotine intake and focus on changing your behaviors, Nicorette can double your chances of successfully quitting.

DRUG FACTS

FIND YOUR QUIT METHOD

Nicorette offers a Find Your Quit Method. It is an interactive tutorial that helps a patient determine which form of Nicorette is best for them and how often to take it.

http://www.nicorettestore.com/quit_method.do

PRICES $58.99 for both strengths (100 pieces)

PRICES

$12.99 for both strengths (20 pieces)

STATISTIC AGAINST COLD TURKEY

Percentage of smokers who want to quit altogether 70%

Percentage of smokers who will try to quit this year 40%

Percentage of smokers who will succeed at quitting smoking on their first try

7%

Percentage of people who will successfully quit smoking cold turkey

3.5%

TIMELINE OF NICORETTE

MARKET SHARE

51.84GlaxoSmithKline plc (GSK)

0.08 (0.15%)

SUMMARY OF MARKET SHARE

Day's Range: 51.51 - 51.94

52wk Range: 48.30 - 56.73

Volume: 2,205,556

Avg Vol (3m): 2,488,850

Market Cap: 124.19B

P/E (ttm): 14.59

EPS (ttm): 3.55

Div & Yield: 3.00 (5.80%)

INCOME STATEMENT

Revenue (ttm): 42.60BRevenue Per Share (ttm): 17.64Qtrly Revenue Growth (yoy): 1.50%Gross Profit (ttm): 29.68BEBITDA (ttm)6: 13.94BNet Income Avl to Common (ttm): 8.74BDiluted EPS (ttm): 3.55Qtrly Earnings Growth (yoy): 190.20%

RECENT CHANGES IN LABELING

The changes that FDA is allowing to these labels reflect the fact that although any nicotine-containing product is potentially addictive, decades of research and use have shown that NRT products sold OTC do not appear to have significant potential for abuse or dependence.

The changes being recommended by FDA include a removal of the warning that consumers should not use an NRT product if they are still smoking, chewing tobacco, using snuff or any other product that contains nicotine—including another NRT.

The FDA also withdrew the former belief that Nicorette could only be used short term. There is no evidence showing that it is harmful to continue use.

COMMON SIDE EFFECTS OF NICORETTE

• Acid or sour stomach

• Belching

• Coughing

• Heartburn

• Indigestion

• Mouth and throat irritation

• Stomach discomfort, upset, or pain

LESS COMMON SIDE EFFECTS OF NICORETTE

• Fast or irregular heartbeat

• Fever with or without chills

• Headache

• Nausea with or without vomiting

• Runny nose

• Shortness of breath, tightness in the chest, trouble with breathing, or wheezing

• Skin rash , itching, or hives

• tearing of the eyes

SIDE EFFECTS OF LEADING PRESCRIPTIONSCall your doctor at once if you have a serious side effect such as:

• seizure (convulsions);

• severe blistering, peeling, and red skin rash;

• fever, swollen glands, rash or itching, joint pain, or general ill feeling;

• confusion, trouble concentrating; or

• hallucinations, unusual thoughts or behavior.

Less serious side effects may include:

• headache or migraine, dizziness, tremors (shaking);

• sleep problems (insomnia), loss of interest in sex;

• nausea, vomiting, constipation, dry mouth;

• appetite changes, weight loss or gain; or

• mild itching or skin rash, increased sweating.

RECOMMENDED USAGE Month 1 - First 2 weeks

10-20 PIECES A DAY

Month 1 - Second 2 weeks8-15 PIECES A DAY

Month 24-10 PIECES A DAY

Month 32-5 PIECES A DAY

Month 4-61 PIECE IF THE URGE TO

SMOKE RETURNS

OTHER HELPFUL HINTS

• Use the “Chew and Park” method: Chew Nicorette gum slowly. When you start to feel a tingling sensation, park the gum between your teeth and cheek and let it remain there until you notice the tingling subsiding. Then, chew again. Repeat the process until the tingle is gone (about 30 minutes).

• If you experience strong or frequent cravings, you can chew a second piece of nicotine gum within the hour, but you should not continuously chew one piece after another.