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Page 1: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Get oriented...

Page 2: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

What do you want to do?

Page 3: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Validate one or more residues in one or more biomolecules

Step 1

Step 2

Ret

rieve

inpu

t file

s fro

m d

atab

ases

...

Page 4: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Validate one or more residues in one or more biomolecules

Step 1

Step 2

Or u

ploa

d yo

ur in

put f

iles.

..

Page 5: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Scroll down to read a summary of the issues found for each residue

Your results will be available on the server for up to a month

Validated residues

Page 6: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Validated residue

Potential issues identified during validation

Page 7: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Validated residue

Valid

ated

mot

ifs(in

stan

ces

of v

alid

ated

resi

dues

)

Type of issue

Potential issues

Location of potential issues

Page 8: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Wrong chirality on atom C1

Inspect each entry using the molecular viewer

Instance of the validated residue

Page 9: Get oriented - WebChemistrywebchem.ncbr.muni.cz/Platform/Content/MotiveValidator/MotiveValid... · Download Input Download Result Summary Details ... Motif/Fragment Validation Command

Don't know where to start?