Georgia Health Sciences University and Health System:

The Big Picture

GDEcD 12/7/11

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• One of ~15 free-standing Health Sciences Universities

• One of ~80 Academic Health Centers (AHC)

• One of only two vertically & horizontally integrated AHCs in GA

Georgia Health Sciences is Georgia’s Public Academic Health Center

Georgia’s only Public Academic Health Center

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Georgia Health Sciences University Mission

To lead Georgia and the world to better health, by providing excellence in biomedical education, discovery, and service

Vision To be a leading research university… and academic health center… while transforming the institution and region into a health care and biomedical research destination

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Academic Health Centers (AHCs): Much More Than a University!

Tomorrow’s Diverse

Workforce

Scientific Discoveries

& New Therapies

Highly Specialized & Quality

Care

Education

Research Clinical care

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Academic Health Center • Hubs of innovation including:

– Education & Training – Research & Discovery – Clinical Care & Service

• An AHC is critical to the: – Quality of medical and health care professions

education & training – Degree of economic impact of the enterprise – Ability to generate translational research – Ability to offer advanced cutting-edge health care

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• Our Health System: – 472 bed acute care adult hospital (GHS Medical

Center) – 160 bed Children's Medical Center (CMC) – 400+ physician multi-specialty group – Various outpatient facilities – In Georgia:

• 2nd largest children’s hospital • The region’s only Level I trauma center • The region’s largest dedicated Cancer Care facility • 2nd largest Medicaid provider

Georgia Health Sciences A Critical Benefit to Georgia

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• Our Health System: – Trains ~450 medical and ~50 dental residents

• ~20% of all GME and 75% of all GDE slots in GA

– GHSU administers facilities and provides care to special populations in Georgia: • Manage the GA War Veterans Nursing Home, for GA DVS • Manage East Central GA Regional Hospital, for GA DBHDD • Manage the care of GA’s 45K inmates for GA DOC

– Provides ~half a million patient visits annually • >50% of all patients are of minority populations • >30% are outside MSA

– Provide >$100 million in uncompensated care/yr

– >$90 million of medical tourism dollars in 2009

Georgia Health Sciences A Critical Benefit to Georgia

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Georgia Health Sciences A Critical Benefit to Georgia

• Our University • Five Colleges with more than 2,400

students, includes • Nation’s 13th oldest & 6th largest medical

school • GA’s only College of Dental Medicine • GA’s largest advanced Nursing degree program • GA’s largest Allied Health Professions program

• 800 clinical training sites throughout GA

• Branch campuses located throughout GA, with various partners • MCG: Albany, Athens, Savannah & Brunswick,

and Rome • CON: Athens and Columbus

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Georgia Health Sciences A Critical Benefit to Georgia

• Our University • Trains 1 in 5 Physicians in GA • Produces the largest number of 1ary care MDs in GA • Trains 1 in 4 Dentists in GA

• Our University produces highly competitive students • 2011 Freshman class entrance scores are above the

national average • 2011 National examinations (USMLE) student pass rate of 99.5% are above national average (93%)

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GHSU: A Decade of Research Growth

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26

32

38

44

50

2001

2002

2003

2004

2005

2006

2007

2008

2009

2010

GHSU NIH funding (in $millions) +89% increase

NIH Budget (in $billions) +53% increase

65

69

73

77

81

85

2001

2002

2003

2004

2005

2006

2007

2008

2009

2010

Increase in GHSU medical school ranking based on NIH

funding (Blue Ridge Institute for Medical

Research)

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• For FY10 - $63M in NIH funding & $90M in total research funding

• 25% increase in sponsored activity funding over last 4 years

• GHSU was the first in GA to offer Phase 1 and Phase 2 clinical trials

• Major research centers in the areas of: – Cancer – Neuroscience & Behavioral Medicine – Cardiovascular Biology – Genomics & Molecular Medicine – Regenerative & Reparative Medicine – Disease Prevention

Georgia Health Sciences A Critical Benefit to Georgia

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Clinical 38%

Research 13% Tuition & Fees

7%

Education Grants

3%

State Appropriations

to GHSU: Education &

Research 27%

Stimulus 6%

Other 6%

University/Academic Sources of Funding

GHSHS/GHSU $1.1 B Enterprise: 2010 Funding Sources

(Operating and Non-Operating Revenue, Excluding Inter-Company Transfers)

Clinical 91%

State Appropriatons to GHS Health

System 6%

Other 3%

Health System Sources of Funding

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AHCs and GHSU

• Like GHSU – Has more schools than 72% of AAHC* members

– Has more employees than 80% of AHCs

– Provides more uncompensated care than 86% of AHCs

– Is integrated with its medical center, more than 50% of AHCs

– Similarly to the average AAHC institutions it has ~600 patient beds

*The Association of Academic Health Centers (AAHC) represents more than 100 institutions nationwide

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• Among the top 20 Georgia employers – Directly employs approximately

10,000 employees – Generates ~50,000 other jobs state-

wide

• $2.1 billion direct annual economic impact – $14 for $1 of State appropriations

• >$8 billion direct annual economic impact state-wide – Including the impact of its workforce,

industry and affiliated providers Source: Tripp Umbach

Workforce Bio-Science Economic

Development Growth

Health Care Provider Growth

Commercialization of Research

Health Sciences Program Growth

Regional MD Expansion

GHSU

Georgia Health Sciences: Enormous Economic Impact

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• ~$350 billion was invested in R&D in the US in 2006 - ~$100 billion from government

• For overall publically funded R&D, Georgia ranked 21 in the US, behind AL, NC, and TN

• But, for R&D performed by universities & colleges, Georgia ranks 12th in total publically-funded R&D (2006) and 16th in NIH funding (2010)

US and GA Investment in R&D

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Olefsky. J Clin Invest. 2007; 117: 270–276

US Production of Scientists: Falling Short

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The Ultimate Weapon Against Cancer: GHSU’s Cancer Research Center

• Research areas include: – Cancer immunology & immunotherapy – Developmental therapeutics – Molecular oncology – Cancer prevention & control

• Hosts Georgia’s only Tumor Tissue Bank

• Participates in over 150 clinical trials

• Cancer Clinical Trials Unit – Moving discoveries from the lab to the bedside – For many patients, their only remaining treatment option

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• How combining a vaccine with a drug can make our own immune system attack cancer cells

• Developing immunotherapy strategies that enhance the efficacy of conventional cancer therapies

• Testing a new compound that may be able to make brain tumors more susceptible to radiation and chemotherapy

• Using state-of-the-art DNA sequencing technology to discover the genetic basis of early-onset breast and colon cancer in African Americans

• Developing new multi-drug strategies for the treatment of the most lethal types of leukemia

GHSU Research Spotlight GHSU Cancer Center

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GHSU Research Spotlight Neurobiology: Brain Mapping Project

1999 Time magazine cover story on the creation of genetically engineered smart mice

2009 Special Edition of US News and World Report on memory discovery

Joe Z. Tsien, Ph.D. Professor, Neurology GRA Eminent Scholar in Cognitive & Systems Neurobiology

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GHSU Research Spotlight Vascular Biology Center

• GHSU ranks #1 in the SE #6 nationally in American Heart Association (AHA) funding

• Diagnosis, prevention and therapy of kidney disease and hypertension

• Discovery of gender-dependent differences in vascular function

• Prevention and repair of microvascular disease associated with acute lung injury and ARDS

• Identification of new targets in obesity- and diabetes-induced vascular disease

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GHSU Research Spotlight Center for Biotechnology &

Genomic Medicine

• ~$70 million federal funding since creation in 2002 ($12M in 2010)

• World’s largest database and biorepository for Type 1 diabetes

• Successfully spun off biotechnology companies (e.g. Jinfiniti Biosciences and ImmunoReg)

• Extensive free health services

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GHSU Research Spotlight Institute for Regenerative & Reparative Medicine

• Stimulating bone growth and repair after injury

• Targeting brain repair after stroke

• Developing partnerships with Wounded Warrior Project, Ft. Gordon, and Charlie Norwood VAMC

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In the U.S., Georgia is negatively ranked in Public Health:

• 31st for the % of adults who smoke

• 39th for the % of adults who are obese

• 41st for the % of adults with T2 DM

• 40th for infant mortality rate

• 41st for teen birth rate

• 43rd & 45th for pre-term & low birth-rate births

• 47th for rates of TB, hepatitis and AIDS

Public Health Challenges in GA

30 counties in Georgia have lower life expectancy than the 3rd world countries of…

– Gaza Strip – El Salvador – Dominican Republic – Thailand

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• Internationally recognized multidisciplinary translational research institute – Over $74 million in NIH funding since its inception

• Unique 30 year research partnership with community, leading in research on: – Ethnic disparities in CVD and diabetes – Childhood obesity and its impact on the future health of

children and adults – The genetic and environmental contributions to disease

processes

GHSU Research Spotlight Georgia Prevention Institute

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• Formulating a clear Strategy to grow our research, clinical, and educational enterprises:

– Research growth will leverage current strengths and expand our clinical/translational/tech transfer capacity

– Clinical growth will focus on expanding our footprint, ensuring that all Georgians have access to the specialized Health Care, and the health maintenance and prevention, they need

– Educational growth will center on expanding our leadership in Advanced Degree Health Professions Training

Georgia Health Sciences Where are we going?

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$200 $332

$445

2010 2015 2020

GHSU Research and Bioscience Industry Economic Impact

($ millions)

1332 2213 2967

2010 2015 2020

GHSU Research and Bioscience Industry Jobs Impact ($ millions)

Economic Impact of Research Growth at GHSU

Adding 100 researchers to GHSU will…

• Increase extramural funding to ~100M/yr

• Create 1600 – 2000 new jobs1

• Generate $8M - $10M in annual state and local tax revenues1

• Produce +200 patents and 10-20 new spinoff companies2

1. Based on metrics provided by Bureau of Economic and Business Research, David Eccles School of Business, University of Utah (2009, vol. 69: num. 2). 2. Projection based on number of patents and new companies at current funding level.

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Total Research Space: GHSU vs. 50th Ranked Institutions

231,929

434,433

465,173

477,271

535,622

574,062

832,170

889,117

1,439,038

#70 GHSU

#51 Case Western

#53 UT Houston

#50 UT Galveston

#52 UT San Antonio

#47 MUSC

#48 U of Cincinnati

#49 U of Illinois

#54 UC Irvine

Research Square Footage

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Becoming a $3B Economic Engine Strategy Growth Factor

(FY10-20) Increased Revenue

Increase in Patient Care Revenues 3% /yr $250M

Increase in research/clinical scientists and research funding

100 FTE 10% productivity

$125M

Increased tuition revenue and state appropriations from increased enrollment

student enrollment 25%; 5% tuition/yr

$50M

Increased Tech Transfer 5X $10M

Philanthropy $15M

Increase in other revenue streams $50M

Total Increased Revenue $500M

Total Direct Economic Impact $3 Billion

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Georgia Health Sciences Why will we succeed?

• We are one of only two vertically & horizontally integrated AHCs in GA, able to address:

– The emerging challenges of the changing health care environment

– The clinical & translational research needs of the future – The continuum of health professions education

• We have over 500 integrated Health Care providers

• We already educate & develop tomorrow’s healthcare leaders

• We have recognized areas of research & clinical care excellence

• We have broad reach, including all of GA and portions of SC

• We have demonstrated ability to sustain long-term partnerships with many communities, state & military agencies

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And after all, we have been dedicated to the welfare of all Georgians for almost 200

years

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GHSU… Much More Than a University

Critical to Georgia’s Health

Critical to Georgia’s Economy

Critical to Georgia’s Future

Thank You