george ntaios md, msc (eso stroke medicine), phd, feso university of thessaly, larissa, greece nice...
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George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO
University of Thessaly, Larissa, Greece
Nice 08/05/2014
A short introduction on
European Stroke Conference / Stroke Guidelines
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Disclosures
Scholarships: European Stroke Organization; Hellenic Society of Atherosclerosis.Honoraria: Medtronic; Quintiles.Speaker fees: Sanofi; Boehringer-Ingelheim.Consultant fees: Boehringer-Ingelheim.Support to attend conferences: Bayer; Sanofi-Aventis; Pfizer; Lundbeck; Boehringer-Ingelheim; Galenica; Elpen; Bristol Myers Squibb. Participation in trials:
ENOS / National co-ordinator (Greece). BPREVISE / Principal investigator. FOURIER / Sub-investigator. GLORIA / Sub-investigator.
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Grading of
Recommendations,
Assessment,
Development and
Evaluation
GRADE
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Population In children during summertime
Intervention chocolate ice-cream
Comparator studying mathematics
Outcome* happiness
Specify the PICO question(s)
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Assessment of quality of studies
RCTs start high
Observational studies start low
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Assessment of quality of studies (downgrade)
Study design and execution (bias)
Inconsistency (heterogeneity, I2)
Indirectness
Imprecision (number of events, confidence intervals)
Publication bias (funnel plot)
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Assessment of quality of studies (upgrade)
Large magnitude of the effect
Dose – response relation
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Grade of evidence
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Summary of Findings (SoF) tables
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Panel discussionOverview