gear grants
Post on 19-Oct-2014
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DESCRIPTION
SC Statewide Alliance for Tissue Biofabrication and Gear Grants support by Roger Markwald, PhDTRANSCRIPT
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GEAR GRANTS & RELATIONSHIP TO CURRENT NSF RII GRANT
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GEAR GRANTS
• Due March 29 2010
• Pilot projects targeted to submitting an extramural grant within 12 months
• Amount of awards (50-100K)
• Peer Reviewed
• 10 pages max (interdisciplinary)
• ALIGN with NSF RII Track 1 Award
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GEAR GRANTS
• Instructions (SC EPSCOR OFFICE)
• Scott Little ([email protected])
• Isabel Sanchez ([email protected])
• Key: alignment with the NSF RII grant “The South Carolina Project”
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NSF-RII Grant
Title “South Carolina Project”
Theme Tissue Based Engineering
Goal To Engineer a Vascular Tree by
Bioprinting
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What is Bioprinting?
Bioprinting/Biofabrication is a computer-aided, robotic Bioprinting/Biofabrication is a computer-aided, robotic layer by layer addition of living building blocks to form 3D layer by layer addition of living building blocks to form 3D functional human tissue constructsfunctional human tissue constructs
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BIOPRINTING
the ability to arrange bio-materials in a controlled but “additive” fashion in
three-dimensional (3D) space.
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BioPrinting Using “BioInk”
BioInk = aggregates of stem cells + hydrogel (morphogens)
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A B C
D E F
G
From Mironov, Markwald et al 2009 in Expert Opinion in Biological Therapy (in press)
BioInk BioInk
Stem cells + hydrogel
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SOUTH CAROLINA PROJECT
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Digital Anatomy
Blueprint
CAD
Bioink
Bioprinter
Biopaper
MATUROGENS
Tissue Constructs
Biomonitoring
I. Pre-processing
II. Processing
III. Post-processing
Components ofOrgan PrintingTechnology
Bioreactors
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Enabling Technologies Required for Engineering a Vascular Tree
Vascular Tree
Bio Ink
BioPaper
BioReactor
BioMonitor
Bio informatics