gastric lavage in vigorous neonates born with meconium stained amniotic fluid

1
COMMENTARY Gastric Lavage in Vigorous Neonates Born with Meconium Stained Amniotic Fluid Rajeev Mehta Received: 5 December 2012 / Accepted: 5 December 2012 / Published online: 20 December 2012 # Dr. K C Chaudhuri Foundation 2012 Meconium stained amniotic fluid (MSAF) is an intra-partum circumstance that occurs in 1015 % of term births and requires medical attention in infants with signs of respiratory distress related to the development of meconium aspiration syndrome [1, 2]. MSAF may have an association with the swallowing of meconium prior to delivery, which may cause feeding problems after birth [3, 4]. Although gastric lavage may purportedly remove meconium from the stomach and reduce gastric irrita- tion, previous observational and randomized clinical studies have not been able to identify a beneficial effect of such a procedure on the prevention of feeding intolerance in neonates born with MSAF [5, 6]. Actually, the harmful effects of gastric lavage (risk for bradycardia, perforation, and aspiration of swal- lowed meconium) may outweigh the expected benefit in vigor- ous infants born through MSAF [4]. The study by Ameta et al. [7] confirms previous observations. Although there appears to be a reduction in the feeding problems, the difference is not statistically significant. The American Academy of Pediatrics and International Guidelines for Neonatal Resuscitation that were published more than a decade ago, do not recommend gastric suctioning in neonates born with MSAF [8, 9]. References 1. Manganaro R, Mamì C, Palmara A, Paolata A, Gemelli M. Inci- dence of meconium aspiration syndrome in term meconium-stained babies managed at birth with selective tracheal intubation. J Perinat Med. 2001;29:4658. 2. Wiswell TE. Handling the meconium-stained infant. Semin Neo- natol. 2001;6:22531. 3. Narchi H, Kulaylat N. Feeding problems with the first feed in neonates with meconium-stained amniotic fluid. Paediatr Child Health. 1999;4:32730. 4. Gelfand SL, Fanaroff JM, Walsh MC. Meconium stained fluid: approach to the mother and the baby. Pediatr Clin N Am. 2004;51:65567. 5. Narchi H, Kulaylat N. Is gastric lavage needed in neonates with meconium-stained amniotic fluid? Eur J Pediatr. 1999;158:3157. 6. Cuello-García C, González-López V, Soto-González A, López-Gue- vara V, Fernández-Ortiz SJ, Cortez-Hernández MC. Gastric lavage in healthy term newborns: a randomized controlled trial. An Pediatr (Barc). 2005;63:50913. 7. Ameta G, Upadhyay A, Gothwal S, Singh K, Dubey K, Gupta A. Role of gastric lavage in vigorous neonates born with meconium stained amniotic fluid. Indian J Pediatr. 2012. doi:10.1007/s12098- 012-0805-x. 8. American Academy of Pediatrics and American Heart Associ- ation. Neonatal resuscitation textbook. 4th ed. Chicago: Amer- ican Academy of Pediatrics and American Heart Association; 2000. pp. 27. 9. Niermeyer S, Ka winkel J, Van Reempts P, Nadkarni V, Phillips B, Zideman D, Azzopardi D, Berg R, Boyle D, Boyle R, Burchfield D, Carlo W, Chameides L, Denson S, Fallat M, Gerardi M, Gunn A, Hazinski MF, Keenan W, Knaebel S, Milner A, Perlman J, Saugstad OD, Schleien C, Solimano A, Speer M, Toce S, Wiswell T, Zaritsky A. International guidelines for neonatal resuscitation: an excerpt from the guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care: international consensus on science. Pediatrics. 2000;106:e29. R. Mehta (*) Department of Pediatrics, Division of Neonatal-Perinatal Medicine, UMDNJ - Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA e-mail: [email protected] Indian J Pediatr (March 2013) 80(3):252 DOI 10.1007/s12098-012-0949-8

Upload: rajeev-mehta

Post on 13-Dec-2016

223 views

Category:

Documents


5 download

TRANSCRIPT

Page 1: Gastric Lavage in Vigorous Neonates Born with Meconium Stained Amniotic Fluid

COMMENTARY

Gastric Lavage in Vigorous Neonates Born with MeconiumStained Amniotic Fluid

Rajeev Mehta

Received: 5 December 2012 /Accepted: 5 December 2012 /Published online: 20 December 2012# Dr. K C Chaudhuri Foundation 2012

Meconium stained amniotic fluid (MSAF) is an intra-partumcircumstance that occurs in 10–15 % of term births and requiresmedical attention in infants with signs of respiratory distressrelated to the development of meconium aspiration syndrome[1, 2]. MSAF may have an association with the swallowing ofmeconium prior to delivery, which may cause feeding problemsafter birth [3, 4]. Although gastric lavage may purportedlyremove meconium from the stomach and reduce gastric irrita-tion, previous observational and randomized clinical studieshave not been able to identify a beneficial effect of such aprocedure on the prevention of feeding intolerance in neonatesborn with MSAF [5, 6]. Actually, the harmful effects of gastriclavage (risk for bradycardia, perforation, and aspiration of swal-lowed meconium) may outweigh the expected benefit in vigor-ous infants born through MSAF [4]. The study by Ameta et al.[7] confirms previous observations. Although there appears tobe a reduction in the feeding problems, the difference is notstatistically significant. The American Academy of Pediatricsand International Guidelines for Neonatal Resuscitation thatwere published more than a decade ago, do not recommendgastric suctioning in neonates born with MSAF [8, 9].

References

1. Manganaro R, Mamì C, Palmara A, Paolata A, Gemelli M. Inci-dence of meconium aspiration syndrome in term meconium-stained

babies managed at birth with selective tracheal intubation. J Perinat Med.2001;29:465–8.

2. Wiswell TE. Handling the meconium-stained infant. Semin Neo-natol. 2001;6:225–31.

3. Narchi H, Kulaylat N. Feeding problems with the first feed inneonates with meconium-stained amniotic fluid. Paediatr ChildHealth. 1999;4:327–30.

4. Gelfand SL, Fanaroff JM, Walsh MC. Meconium stained fluid:approach to the mother and the baby. Pediatr Clin N Am.2004;51:655–67.

5. Narchi H, Kulaylat N. Is gastric lavage needed in neonateswith meconium-stained amniotic fluid? Eur J Pediatr.1999;158:315–7.

6. Cuello-García C, González-López V, Soto-González A, López-Gue-vara V, Fernández-Ortiz SJ, Cortez-Hernández MC. Gastric lavagein healthy term newborns: a randomized controlled trial. An Pediatr(Barc). 2005;63:509–13.

7. Ameta G, Upadhyay A, Gothwal S, Singh K, Dubey K, Gupta A.Role of gastric lavage in vigorous neonates born with meconiumstained amniotic fluid. Indian J Pediatr. 2012. doi:10.1007/s12098-012-0805-x.

8. American Academy of Pediatrics and American Heart Associ-ation. Neonatal resuscitation textbook. 4th ed. Chicago: Amer-ican Academy of Pediatrics and American Heart Association;2000. pp. 2–7.

9. Niermeyer S, Ka winkel J, Van Reempts P, Nadkarni V, Phillips B,Zideman D, Azzopardi D, Berg R, Boyle D, Boyle R, Burchfield D,Carlo W, Chameides L, Denson S, Fallat M, Gerardi M, Gunn A,Hazinski MF, Keenan W, Knaebel S, Milner A, Perlman J, SaugstadOD, Schleien C, SolimanoA, SpeerM, Toce S,Wiswell T, Zaritsky A.International guidelines for neonatal resuscitation: an excerpt from theguidelines 2000 for cardiopulmonary resuscitation and emergencycardiovascular care: international consensus on science. Pediatrics.2000;106:e29.

R. Mehta (*)Department of Pediatrics,Division of Neonatal-Perinatal Medicine,UMDNJ - Robert Wood Johnson Medical School,New Brunswick, NJ 08901, USAe-mail: [email protected]

Indian J Pediatr (March 2013) 80(3):252DOI 10.1007/s12098-012-0949-8