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1 LAMPIRAN A TEMPLATE FOR BRIEF CURRICULUM VITEA (CV) TO BE COMPLETED FOR ALL RESEARCHERS. On-going grants : 1. RU Team grant (1001/PPSP/853005) entitled “Novel Approaches For Detection of Disease Recurrence, Risk Reduction And Improved Management Of Breast Cancer” (RM 906, 644.90) (15 Mac 2013-14 Mac 2017) (main-investigator). 2. Research Acculturation Collaborative Effort (RACE). "Discovering the effects of Transforming Growth Factor-Beta 1 and Cytochalasin-B to microtissues in a microfluidic device" (RM49,350.00) (29 Jan 2015 - 26 June 2017) 3. RACE matching (1001/PPSP/AUPRM00543). "Mentor bagi projek Research Acculturation collaborative Effort (RACE) Phase 3/2015 for a project entitled “Discovering the effect of Transforming Growth Factor -Beta 1 and Cytochalasin-B to the biophysical properties of microtissues treated in a microfluidic device” for Dr Soon Chin Fong from Universiti Tun Hussein Onn (UTHM)" (RM 10,000.00) (14 May 2015-31 Dec 2016) 4. RUI (1001/PPSK/812180). " Anti-asthmatic activity of bioactivity-guided fractionated Tiger Milk Mushroom or Lignosus rhinocerus extract in asthmatic airway inflammation rodent model " (RM 160,538.00) (1 Mac 2015-28 Feb 2018) 5. Dana Inovasi Awal. "In Vitro Cultivation of Tiger Milk Mushroom (Lignosus rhinocerus) for Sustainable Production of BreatheEZI®" (RM 49,127.00) (1/9/2014-31/8/2016) 6. Insentif Graduate on Time (GOT) for PhD student Loo Keat Wei (RM 5,000.00) (15 Dec 2015 - 14 Dec 2017) 1. PERSONAL DATA Name : Professor Dr Gan Siew Hua DOB Nationality : : 8 Mar 1972 Malaysian Current Position : Lecturer, Human Genome Centre Qualifications : BSc (Pharmacy), M. Pharm (Clin Pharmacy), PhD (pharmacogenetics & pharmacokinetics) Field of specialization : Toxicology, pharmacogenetics, pharmacokinetics Tel (office) : +609-7676803/ 012-9859830 Fax : 09-7653370 email : [email protected] Websites Researcher ID Scopus ID : https://www.researchgate.net/profile/Hua_Gan/ http://www.medic.usm.my/genome/ A-6266-2011 34769560600 2. ACHIEVEMENTS

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LAMPIRAN A

TEMPLATE FOR BRIEF CURRICULUM VITEA (CV) TO BE COMPLETED FOR ALL RESEARCHERS.

On-going grants : 1. RU Team grant (1001/PPSP/853005) entitled “Novel Approaches For Detection of Disease Recurrence, Risk Reduction And Improved Management Of Breast Cancer” (RM 906, 644.90) (15 Mac 2013-14 Mac 2017) (main-investigator). 2. Research Acculturation Collaborative Effort (RACE). "Discovering the effects of Transforming Growth Factor-Beta 1 and Cytochalasin-B to microtissues in a microfluidic device" (RM49,350.00) (29 Jan 2015 - 26 June 2017) 3. RACE matching (1001/PPSP/AUPRM00543). "Mentor bagi projek Research Acculturation collaborative Effort (RACE) Phase 3/2015 for a project entitled “Discovering the effect of Transforming Growth Factor-Beta 1 and Cytochalasin-B to the biophysical properties of microtissues treated in a microfluidic device” for Dr Soon Chin Fong from Universiti Tun Hussein Onn (UTHM)" (RM 10,000.00) (14 May 2015-31 Dec 2016) 4. RUI (1001/PPSK/812180). " Anti-asthmatic activity of bioactivity-guided fractionated Tiger Milk Mushroom or Lignosus rhinocerus extract in asthmatic airway inflammation rodent model " (RM 160,538.00) (1 Mac 2015-28 Feb 2018) 5. Dana Inovasi Awal. "In Vitro Cultivation of Tiger Milk Mushroom (Lignosus rhinocerus) for Sustainable Production of BreatheEZI®" (RM 49,127.00) (1/9/2014-31/8/2016) 6. Insentif Graduate on Time (GOT) for PhD student Loo Keat Wei (RM 5,000.00) (15 Dec 2015 - 14 Dec 2017)

1. PERSONAL DATA

Name : Professor Dr Gan Siew Hua

DOB Nationality

: :

8 Mar 1972 Malaysian

Current Position :

Lecturer, Human Genome Centre

Qualifications :

BSc (Pharmacy), M. Pharm (Clin Pharmacy), PhD (pharmacogenetics & pharmacokinetics)

Field of specialization : Toxicology, pharmacogenetics, pharmacokinetics

Tel (office) : +609-7676803/ 012-9859830

Fax : 09-7653370

email : [email protected]

Websites Researcher ID Scopus ID

: https://www.researchgate.net/profile/Hua_Gan/ http://www.medic.usm.my/genome/ A-6266-2011 34769560600

2. ACHIEVEMENTS

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Completed grants : 1. Science Fund grant (305/PPSP/6113206) entitled "Artesunate & amodiaquine: tolerability & pharmacokinetics study in healthy normal volunteers of non-fixed and fixed combinations & their correlation with the CYP2A6 and CYP2C8 gene (RM 139,994.00) (main-investigator).

2. Short term grant (304/ PPSP/ 6131480) entitled "Stereoisomer concentrations of amphetamine, amphetamine derivatives & metabolites in saliva and urine in comparison with blood plasma levels utilizing a validated stereoselective gas chromatography ion-trap mass spectrometry assay" 15 March 2007- 14 March 2009 (RM 19,015.00) (main-investigator).

3. Research University Grant: Niche Area PPSP (1001/PPSP/8120205) entitled “Antimicrobial properties of honey” (RM 48,876.00) (co-investigator).

4. IRPA EA grant (305/PPSP/612222) entitled "Population pharmacokinetics of repaglinide in Type 2 diabetes mellitus patients and genetic polymorphisms of CYP3A4 and CYP2C8" (RM 234,410.00) (main-investigator).

5. Incentive grant entitled “Determination of Amphetamine and Methamphetamine in Urine using Gas Chromatography Mass Spectrometry (GCMS)” (1,000.00) (main-investigator).

6. WHO grant (305/PPSP/6150066/E108. “Artesunate and amodioquine tolerability & pharmacokinetic study in healthy volunteers of non-fixed and fixed combinations” (68,398.00) (co-investigator).

7. Short term grant (304/PPSP/6131450) entitled “Genetic polymorphisms of CYP3A4 & CYP2C8 in healthy volunteers administered with repaglinide” (19,947.00) (main-investigator).

8. Research University (RU) Grant: Niche Area (1001/PPSP/8120201) entitled “Identification of chemical constituents & standardization of madu lebah tualang” (124,615.00) (co-investigator).

9. Research University (RU) Grant: Niche Area (1001/PPSP/ 8120213) entitled “An open label randomised control trial comparing honey with ciprofloxacin as prophylaxis against febrile neutropenia” (74,192.00) (co-investigator).

10. Fundamental Research Grant Scheme (FRGS) (203/PPSP/6171105) entitled "Expression in vitro of TGF-B in honey treated Human Skin Fibroblasts" (RM 134,000.00) (co-investigator).

11. Research University (RU) Grant: Potential Project (1001/PPSP/815022) entitled “Genetic polymorphism of drugs, the in vitro metabolisms of MDMA, artesunate & amodiaquine and interindividual variability to their responses” (RM 270,375.00) (main-investigator).

12. Incentive grant for supervising a postgraduate candidate (Ms Wardah Yusof, PhD candidate) (1001/PPSP/8121005) entitled “Development and evaluation of CYP2A6 & CYP2C8 E. coli model systems to study the in vitro metabolism of artesunate and amodiaquine” (RM 15,000.00) (main-investigator).

13. Research University (RU) Grant: Fundamental Project (1001/PPSP/811082) entitled "The Omega-3 & Omega-3 index blood levels and their association with demographic, clinical characteristics, fasting blood sugar & lipid profiles among Health staff's populations" (co-investigator).

14. Postgraduate research scheme Research University Grant (USM-RU-PRGS) for Ms Tang Suk Peng:(1001/PPSP/8142002) entitled “GC/MS

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method development and validation for quantification of paraquat” (co-investigator).

15. Short term grant (304/PPSP/6139064) entitled “High Performance Liquid Chromatography Method Development & Validation for the determination of imatinib’s serum concentrations” (main-investigator).

16. Short term grant (304/PPSP/61310003) entitled “The effect of Centella Asiatica on viral replication and cytokine production during in vitro dengue infection” (co-investigator).

17. Short term grant (304/PPSP/61310011) entitled “High Performance Liquid Chromatography Method Development & Validation for simultaneous determination of Arabinoside-C and doxorubicin concentrations in human plasma” (main-investigator).

18. Short term grant (304/PPSP/61310014) entitled “Anti-Hepatitis A Seroprevalence Among Patients With Chronic Viral Liver Disease In HUSM And Its Association With CYP3A4 Polymorphism” (co-investigator).

19. Incentive grant. (1001/PPSP/8121005) entitled ''HPLC Method Development & Validation of Therapeutic Cancer Drug Monitoring and Mechanism Study of Imatinib Mesylate Drug Resistance in Chronic Myelogenous Leukaemia'' June 2010 - June 2012. RM 10,000.00 (main-investigator).

20. Research University (RUI) Grant: Potential Project (1001/PPSP/815058) entitled ''Identification of Chemical Compounds in Ten Malaysian Honey Samples and Determination of Their Purity in Comparison to Manuka Honey''. Aug 2010 - Jul 2012. RM 248,720.90 (main-investigator).

21. Research University (RU) Grant (1001/PPSP/812094) entitled “Analysis of Genetic polymorphisms risk factors for Type II diabetes mellitus among Malaysian Malays: A Pharmacogenetics Study. Co-investigator” (1/5/2011 – 30 Apr 2014). (RM 150, 000.00) (co-investigator).

22. Research University (RU) Potential Project. (1001/PPSP/815073) entitled ''The Effects of Vitamin supplementation and MTHFR (C677T) and A1298C genotypes on vitamin B12, homocycteine, folate levels and stroke disability in a Malaysian population.'' 15/8/11 - 14/8/14 (RM 249, 818.00) (main-investigator).

23. APEX Delivering excellence 2012 (DE 2012) entitled “Clinical relevance of efflux, influx and metabolizing enzymes in intra-extracellular disposition of imatinib mesylate in chronic myeloid leukaemia patients” (RM 190 000.00) (1 Nov 2012-31 Oct 2014) (co-investigator).

24. Fundamental Research Grant Scheme (FRGS) (203/PPSP/6171148) entitled “Molecular mechanisms of the actin-associated protein HIP1R on malignant B-cell migration" 1/6/2012- 31/5/2014 (RM 125 000.00) (co-investigator).

25. Research University (RU) (1001/PPSP/815094) entitled “The association of MTHFR C677T & A1298, TNF-A 308 G/A, IL-1β +3953 C/T and ETA 231 AG gene polymorphisms with migraine” 15 Jul 2012 -14 Jul 2015 (RM 216 765.74) (co-investigator). 26. Research University (RU) (1001/PPSP/813055) entitled “Evaluation Of Neuroprotective Effects Of Tualang Honey On Paraquat-Induced Oxidative Stress & Dopaminergic Neuron Damage In The Rat Brain” (1 Jul 2012-30 Jun 2014) (RM 243010.93) (co-investigator). 27. COMSTECH/TWAS “Antioxidative effects of oral administration of honey samples on myocardial ischemia-reperfusion in rat heart” (USD 12

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000) Grant No 11-177 RG/PHA/AS_C-UNESCO FR:3240262650 (main-investigator). 28. Research University (RU) grant entitled “Genome-wide gene promoter DNA methylation study on response to oral anti-diabetics in Malay male patients with type II diabetes mellitus” (RM 196,308.00) (Jan 2013-Dec 2015) (co-investigator). 29. Research University (RU) grant (1001/PPSP/812103)” Imatinib treatment in chronic myeloid leaukaemia (CML): Understanding the fundamental pharmacokinetic and pharmacogenetic mechanisms for variation in response” (RM 227,735.00) (1 Oct 2012-30 Sep 2015) (co-investigator). 30. Research University (RU) grant (1001/PPSG/813065) “In vivo teratogenicity & anti-allergic effects of Lignosus rhinocerus in an asthmatic rodent model and their possible bioactive constituents” (RM 220,293.00) (1 Oct 2012-30 Sep 2015) (co-investigator). 31. University-Industry/ Flagship Collaboration Grant 2012 (BJIM) (PI-2012-012) entitled "Capacity Building on Whole Transcriptomic Analyses using Next-Generation Sequencing for understanding several human genetic diseases; A mutual partnership between Human Genome Center USM and Malaysian Genomics Resource Centre Bhd" (main-investigator) (RM 49,945.00) (1 Sep 2012-31 Aug 2015). 32. RU Team grant (1001/PPSP/852001) entitled “Tualang and acacia honey supplementation for type 2 diabetes patients” (RM500,000.00) (1 Jul 2013-30 Jun 2016) (co-investigator). 33. Incentive grant for supervising a postgraduate candidate (Mr Chua Yung An, PhD candidate PUD 0004/09): (1001/PPSP/8121005) “A study of the association between CYP2C9 genotypes with vitamin K-dependent haemostatic markers among stable warfarinized patients” (RM 15,000.00) (May 2010-May 2013) (main-investigator). 34. Research University (RU) Grant: Potential Project 1001/PPSP/812082 “Alteration Of Gene Expression Profile In Scalp Hair Follicle During Cancer Chemotherapy" (RM 211 170.00) (15/6/11-14/6/14) (co-investigator). 35. Short term 304/PPSP/61312019 ”Development of proposal for a local warfarin doing guideline for safer anticoagulation treatment based on vitamin K-dependent haemostatic markers” (RM 29 410.00) (1 June 2012-31 May 2014) (co-investigator).

Graduated students : 1. (PhD) Ms Ruzilawati Abu Bakar (main supervisor) 2. (MSc) Ms. Nurul Syazana Mohamad Shah (co-supervisor) 3. (PhD) Mr Salisu Buhari (co-supervisor) 4. (Msc) Mr Tan Ka Liong (main supervisor) 5. (PhD) Ms. Wan Raihana binti Wan Aasim (main supervisor). 6. (PhD) Ms Loo Keat Wei (main supervisor), 2014 7. (PhD) Mr Munvar Miya Shaikh (main supervisor), 2015 8. (PhD) Mr Mohamed Moniruzaman (PhD) (main supervisor) 2015 9. (PhD) Mr Chua Yung An (PhD) (main supervisor) 2016 10.(PhD)Ms. Wardah binti Yusof (PhD) (main supervisor)- viva 1st Aug 2016 11.(PhD) Mr Johnathan A/L Malagobadan (PhD) (co-supervisor)- viva 14th Aug 2016 12.(PhD) Dr Murtala Abu bakar (PhD) (main-supervisor)- pending viva 13.(PhD) Ms Tang Suk Peng (PhD) (co-supervisor)- pending viva

Postgraduate Under supervision

: 1. Mr Asiful Islam (PhD) (co-supervisor) 2. Mr Ahmad Aizat (PhD) (co-supervisor) 3. Ms. Fahmida Alam (PhD) (co-supervisor) 4. Ms Najlaa (MSc) (co-supervisor) 5. Ms Syazwani (MSc) (co-supervisor)

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Postgraduate examination

1. Internal Examiner for an MMed Dissertation “The effect of Vitamin E on Basic Fibroblast Growth Factor Levels in Human Fibroblast Cell Culture” for Dr Shawaltul Akma bt Harun Nor Rashid (Dep of Plastic Surgery), Universiti Sains Malaysia, 21

st Feb 2007.

2. Internal Examiner for MMed Dissertation “A study of mitochondrial

A1555G mutation in aminoglycoside-induced ototoxicity” by Dr Eshamsol Kamar bin Omar (Dep of Otorhinolaryngology- Head & Neck Surgery), Universiti Sains Malaysia, 31

st Jul 2008.

3. Internal Examiner for Masters in Med (Anesthesiology) candidate

Dr Azlan Sani Shamsuddin for the Academic session 2011/2012 for a dissertation entitled “A pilot study of Cytochrome P450 Polymorphism in chronic pain”.

4. Internal examiner for an MMed thesis entitled "Association of NDP Gene Mutations & Environmental Risk Factors in Retinopathy of prematurity among Malay population" by Dr Abdul Salim Ismail, Masters in Medicine (Ophthalmogy) 2012/2013.

5. Internal examiner for an MSc thesis entitled “Development of a Cell-Based Green Fluorescen Protein Assay for the Screening of CYP3A4 Inducers and Inhibitors” by Mr Seah Tiong Chai from Institut Farmaseutikal dan Nutraseutikal Malaysia, June 2013.

6. Internal examiner for MSc candidate from Human Genome Centre named Mr. Au Zian Liang for a thesis entitled “Influence of Multi Drug Resistance ABCB1, ABCG2, ABCC1 and ABCC2 Gene polymorphisms in mediating resistance to imatinib mesylate in chronic myeloid leukaemia patients” viva date on 2 June 2014.

7. Internal Examiner for an MSc thesis entitled "ldentification of Chemical Constituents in Different Propolis Extracts and Their ln-Vitro Antimicrobial Activity Against Propionibacterium Acnes and Staphylococcus Epidermidis" by Ms Tuan Nadrah Tuan Naim, Jul 2015.

8. External Examiner for an MSc candidate from Universiti Malaya, Kang In Nee (MGN 070023) entitled, Functional Characterisation of a novel N132D mutation in the thyroid transcription Factor-2 (TTF-2) gene and mutational analysis of the thyroid peroxidase (TPO) gene in patients with congenital hypothyroidism, 18 Jan 2010.

9. External examiner for a PhD thesis from Griffith University, Australia for a candidate named Ms Claudia Gasparini, for a thesis entitled "Identification of Migraine Susceptibility Genes: Candidate Gene Studies", 2014.

10. External examiner for Sujatha Suthandiram for a PhD thesis entitled

“Molecular Analysis Of Various Candidate Genes With Lymphoproliferative Disorders (LPDS) And Association With Methotrexate Related Toxicities In A Multiethnic Population”. 14 Jul 2015.

11. External examiner for a PhD thesis entitled “Physiological & Biochemical Response Of Withania Somnifera, Emblica Officinalis And Bacopa Monnieri Extracts On Hexavalent Chromium [Cr (Iv)] Induced Oxidative Stress In Rats (Rattus Norvegicus)” by Mr Naveed Shuja from University of Lahore, Pakistan, 2015.

12. External Examiner for an MSc Thesis from Universiti Malaya entitled “The role of genetic polymorphims and HIa Variants on Clinical Outcomes in Malaysian Renal Transplant Patients on Calcineurin” by Rhanye Mac Guad (MGN1200060), Jul 2016.

13. External Examiner for a PhD Thesis from Universiti of Lahore,

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Pakistan entitled “Phytochemical and Antioxidative characterization of trigonella foenum-andrographis lineata and eclipta alba in an animal model” by Javed Iqbal (DPCH-02143001) Jul 2016.

Publications : 1. PUBLICATIONS IN PEER-REVIEWED JOURNALS

2. Gan S. H. & Ismail, R. Postoperative pain management: Is it adequate? A preliminary study. 3

rd National Symposium on Health

Sciences, Universiti Kebangsaan Malaysia (2000); 409-412. 3. Gan, S. H. & Ismail, R. (2001). Validation of a high-performance

liquid chromatography method for tramadol and O-desmethyltramadol in human plasma using solid-phase extraction. J. Chromatogr. B. 759, 325-335. (ISI-indexed, IMPACT FACTOR 2.971).

4. Gan S. H. & Ismail, R. (2001). High-performance liquid

chromatographic determination of tramadol hydrochloride and O-desmethyltramadol in human plasma. Asia Pacific J. Pharmacol. 15 (Suppl. 1).

5. Gan S. H., Ismail, R., Wan Adnan, W. A. & Zulmi, W. (2001). Can

the Visual Analogue Scale (VAS) be used to measure postoperative pain? Asia Pacific J. Pharmacol. 15 (Suppl. 1).

6. L.K. Teh, Ismail, R., Gan S. H., Rohana, Y & Abdul Rashid, A. R.

(2001). Genetic polymorphism of CYP2D6 among Malays in Malaysia. Asia Pacific J. Pharmacol. 15 (Suppl. 1).

7. Gan S. H., Ismail, R., Wan Adnan, W. A. & Zulmi, W. (2001).

Relationship between personality and debrisoquine hydroxylation capacity. Malaysian Journal of Medical Sciences 8 (2), 71-72.

8. Gan, S. H., Ismail, R., Wan Adnan, W. A. & Zulmi, W. (2002).

Method development and validation of high-performance liquid chromatography method for tramadol in human plasma using liquid-liquid extraction. J. Chromatogr. B. 772(1), 123-129. (ISI-indexed, IMPACT FACTOR 2.971).

9. Gan S. H., Ismail, R., Wan Adnan, W.A. & Zulmi, W. (2002).

Correlation of tramadol pharmacokinetics and CYP2D6*10 genotype in Malaysian subjects. J. Pharm. Biomed. Appl. 30(2), 189-195. (ISI-indexed, IMPACT FACTOR 2.76).

10. Gan S. H., Ismail, R., Wan Adnan, W.A. & Zulmi, W. (2003).

Standard CYP2D6 genotyping procedures fail for the CYP2D6*5 and duplication alleles when hair roots are used as a source of DNA. Clin. Chimica Acta. 329, 61-68. (ISI-indexed, IMPACT FACTOR 2.96).

11. Gan S. H., Ismail, R., Wan Adnan, W.A., Zulmi, W.,

Kumaraswamy, N. & Larmie, E. T. (2004). Relationship between Type A and B personality and debrisoquine hydroxylation capacity. Br. J. Clin. Pharmacol. 329, 61-68. (ISI-indexed, IMPACT FACTOR 2.68).

12. Gan S. H., Ismail, R., Wan Adnan, W.A., Zulmi, W., Jelliffe, R. W.

(2004). Population Pharmacokinetic Modelling of tramadol with application of the NPEM algorithms. J. Clin. Pharm. Therap. 29, 455-63. (ISI-indexed, IMPACT FACTOR 1.36).

13. Gan S. H., Ismail, R., Wan Adnan, W. A. & Zulmi, W. (2004).

Clinical relevance of CYP2D6 genetic polymorphism on the pharmacokinetics of tramadol. Malaysian Journal of Medical Sciences 11 (1), 112-113.

14. Gan S. H., Ismail, R., RW Jelliffe, Wan Adnan, W. A. & Zulmi, W.

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(2006). Population pharmacokinetics modeling of tramadol with application of the NPEM algorithms. Malaysian Journal of Medical Sciences 13 (2), 117.

15. Ruzilawati Abu Bakar, Gan SH & Zabidah Ismail. (2006) Method

development & validation of an HPLC method for repaglinide in human plasma. Malaysian Journal of Medical Sciences 13 (2), 117.

16. Abu Bakar Ruzilawati, Mohd Suhaimi Abd. Wahab, Ahmad Imran,

Zabidah Ismail & Gan SH (2007). Method development and validation of repaglinide in human plasma by HPLC and its application in pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis 43, 1831-1835. (ISI-indexed, IMPACT FACTOR 2.76).

17. Gan SH, Ismail R, Jelliffe RW, Wan Adnan WA & Zulmi W. (2007).

Impact of CYP2D6 genetic polymorphism on tramadol's pharmacokinetics & pharmacodynamics. Molecular Diagnosis & Therapy, 11(3) 171-181. (ISI-indexed, IMPACT FACTOR 1.39).

18. Abu Bakar Ruzilawati, Mohd Suhaimi Abd. Wahab, & Gan SH (2007). Genetic polymorphisms of CYP3A4: CYP3A4*18 allele is found in five healthy Malaysian subjects. Clin. Chimica Acta, 383, 158-162. (ISI-indexed, IMPACT FACTOR 2.96).

19. Shimaa ABS, Sulaiman SA, A. Wahab MS, Gan SH, Ismail Z, Lope

Pihie AH, Ismail R, Lam CK & Yuen KH (2007). Pharmacokinetic Interaction between propranolol & Eurycoma longlifolia extract. Malaysian Journal of Medical Sciences 14 (S1), 105.

20. Wan Raihana WA, SH Gan, S.C. Tan (2008). Development of a

simultaneous liquid-liquid extraction and chiral derivatization method for stereospecific analysis of amphetamine-type stimulants in human urine using fractional factorial design. Biomedical Chromatography Journal 22, 1035-1042. (ISI-indexed, IMPACT FACTOR 1.61).

21. Chua YA, Nurhaslina H & SH Gan (2008). Hyperthermic effects of

Durio Zibethinus and Its Interaction with Paracetamol. Methods Exp Findings, 30(10), 739-743. (ISI-indexed, IMPACT FACTOR 1.00).

22. Wan Raihana WA, Tan SC & Gan SH (2008). A rapid method for

stereoselective analysis of amphetamine-type stimulants using simultaneous liquid-liquid extraction and chiral derivatization. Drug Metabolism Reviews 40 (S1), 41-42. (ISI-indexed, IMPACT FACTOR 6.24).

23. Ruzilawati Abu Bakar, M Suhaimi & Gan SH (2008). Effects of

CYP3A4*18 on repaglinide’s pharmacokinetics. Drug Metabolism Reviews 40 (S1), 139. (ISI-indexed, IMPACT FACTOR 6.24).

24. Wardah Y & SH Gan (2008). Detection of CYP2A6 variant alleles

commonly found in Asian populations by a duplex nested PCR. Drug Metabolism Reviews 40 (S1), 141. (ISI-indexed, IMPACT FACTOR 6.24).

25. Wardah Y & SH Gan (2009). High prevalence of CYP2A6*4 and

CYP2A6*9 alleles among Malaysian population. Clinica Chimica Acta (403), 105-109. (ISI-indexed, IMPACT FACTOR 2.96).

26. SH Gan, Ramli N & Mukiar N (2009). Dual effects of low & high

dose caffeine. Latin American J Pharmacy 28(3), 465-9. (ISI-indexed, IMPACT FACTOR 0.308).

27. Navaratnam V, Ramanathan S, Wahab MS, SH Gan, Mansor SM,

Kiechel JR, Vaillant M, Taylor WR, Olliaro P. (2009). Tolerability and pharmacokinetics of non-fixed and fixed combinations of

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artesunate and amodiaquine in Malaysian healthy normal volunteers. Eur J Clin Pharmacol., 65(8), 809-21. (ISI-indexed, IMPACT FACTOR 2.5).

28. Hern-Tze Tan, Rosliza A Rahman, SH Gan, AS Halim, Siti Asma’

Hassan, Siti Amrah Sulaiman, Kirnpal-Kaur B. S. (2009) “Antibacterial properties of Malaysian Tualang honey against wound and enteric microorganisms: Comparison with Manuka honey“. BMC Complementary & Alt. Med., 9, 34-42. (ISI-indexed, IMPACT FACTOR 2.01).

29. Wardah Y & SH Gan (2009). Simultaneous detection of

CYP2C8*2, CYP2C8*3, CYP2C8*4 & & CYP2C8*5 alleles by a nested PCR. Asia Pacific Journal of Molecular Biology & Biotechnology, 17(2), 39-45.

30. Ruzilawati A Bakar, M Suhaimi A Wahab, SH Gan (2010).

Population pharmacokinetic modelling of repaglinide in healthy volunteers by using nonparametric adaptive grid (NPAG) algorithm. J Clin Pharmacy Therap 35, 105-112. (ISI-indexed, IMPACT FACTOR 1.755).

31. Nurul Syazana MS, SH Gan, Halim AS (2010). Volatile

Composition Of Malaysian Tualang (Koompasia Excelsa) Honey. J ApiProduct & ApiMed Sc 2(1): 37.

32. M.I. Khalil, S.A. Sulaiman, SH Gan (2010). Determination of 5-

hydroxymethylfurfural content in ten Malaysian honeys. J ApiProduct & ApiMed Sc 2(1): 44.

33. S A b Salman, S A Sulaiman, M S A Wahab, Z Ismail, SH Gan

(2010). HPLC method validation for the detection of propranolol in human plasma. Tox Mech Methods 10(3), 137-142 (ISI-indexed, IMPACT FACTOR 0.75).

34. S A b Salman, Siti Amrah S, M S A Wahab, R Ismail, Yuen KH, Z

Ismail, SH Gan. Modification of Propranolol's Bioavailability by Eurycoma Longifolia Water-Based Extract. (2010). J Clin Pharmacy Therap 35(6), 691-6 (ISI-indexed, IMPACT FACTOR 1.755).

35. Ruzilawati Abu Bakar, Mohd Suhaimi Abd. Wahab, Imran Ahmad,

Zabidah Ismail and Gan Siew Hua. Determination of repaglinide in human plasma by HPLC. Accepted to be published in Proceedings of the British Pharmacological Society at http://www.pa2online.org. (ISI-indexed, IMPACT FACTOR 2.80).

36. Abu Bakar Ruzilawati, Mohd Suhaimi Abd. Wahab, Ahmad Imran,

Zabidah Ismail & Siew Hua Gan. Validated HPLC method for determination of repaglinide in human plasma using liquid-liquid extraction. Accepted to be published in Proceedings of the British Pharmacological Society at http://www.pa2online.org (ISI-indexed, IMPACT FACTOR 2.80).

37. A. B. Ruzilawati and S. H. Gan. (2010). CYP3A4 genetic

polymorphism influences repaglinide's pharmacokinetics. Pharmacology. 85:357-364. (ISI-indexed, IMPACT FACTOR 1.894).

38. MI Khalil, SA Sulaiman, SH Gan (2010). High 5-hydroxymethylfurfural concentrations are found in Malaysian honey samples stored for more than one year. J Food Toxic (ISI-indexed, IMPACT FACTOR 2.321) (48)10, 2388-92.

39. Mistiran AF, Abdullah AD, Gan SH. (2010). HPLC method

development & validation for arabinoside-C & doxorubin concentrations in human serum. J Toxicology Mechs & Methods 20(8) 472-481 (ISI-indexed, IMPACT FACTOR 0.75).

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40. Ruzilawati A Bakar, MS Ab Wahab & SH Gan (2010). Blood

glucose levels in healthy volunteers administered with repaglinide and genetic polymorphisms of CYP3A4 and CYP2C8. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 163. (IMPACT FACTOR 2.308, ISI-indexed).

41. Ruzilawati A Bakar, SH Gan & MS Ab Wahab (2010). Population

pharmacokinetics of repaglinide in healthy Malaysian subjects and genetic polymorphisms of CYP3A4 and CYP2C8. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 163. (IMPACT FACTOR 2.308, ISI-indexed).

42. Siew Hua Gan, PCS Tan, SK Hassan, N Abdullah (2010).

Correlation of cytochrome P450 3A4*18 genetic polymorphisms with postoperative fentanyl requirements. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 291. (IMPACT FACTOR 2.308, ISI-indexed).

43. Siew Hua Gan, AF Mistiran & AD Abdullah (2010). HPLC method

development for the simultaneous determination of Arabinoside-C and Doxorubicin concentrations in human serum. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 291-292. (IMPACT FACTOR 2.308, ISI-indexed).

44. KL Tan, R Hassan & SH Gan (2010). HPLC method development

& validation for the determination of Imatinib Mesylate in human serum. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 608. (IMPACT FACTOR 2.308, ISI-indexed).

45. YA Chua, WZ Wan Abdullah & SH Gan (2010). HPLC method

development & validation for the determination of Warfarin in human plasma. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 237. (IMPACT FACTOR 2.308, ISI-indexed).

46. Wardah Yusof and SH Gan (2010). The influence of CYP2A6

polymorphism on artesunate and amodiaquine tolerability. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 679. (IMPACT FACTOR 2.308, ISI-indexed).

47. SP Tang, SA Sulaiman & SH Gan (2010). Gas chromatography

mass spectrometry (GC/MS) method optimization & validation for detection of paraquat poisoning. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 610. (IMPACT FACTOR 2.308, ISI-indexed).

48. W R Wan Aasim, SH Gan, SC Tan (2010). A validated

stereoselective assay for 3,4-methylenedioxymethamphetamine in human urine samples. Basic & Clinical Pharmacology & Toxicology 107, (Suppl.1), 644. (IMPACT FACTOR 2.308, ISI-indexed).

49. F Ahmad, NAC Hamzah, N Mustaffa & SHGan (2010). CYP3A4

polymorphisms among chronic viral hepatitis B and C liver disease patients. J Gastroenterology & Hepatology, 25 (2): A 101 (IMPACT FACTOR 2.317, ISI-indexed).

50. F Ahmad, NAC Hamzah, N Mustaffa & SHGan (2010). Older Age

predicts higher anti-hepatitis A Virus seroprevalence among chronic viral hepatitis B and C liver disease patients in Hospital Universiti Sains Malaysia, J Gastroenterology & Hepatology, 25 (2): A74 (IMPACT FACTOR 2.317, ISI-indexed).

51. W. R. Wan Aasim, S.H. Gan & S.C. Tan (2011). A new validated

stereoselective method for determination of concentrations of amphetamine-type stimulants and metabolites in human urine using a simultaneous extraction – chiral derivatization approach. J Chromatography B 879; 8-16 (ISI-indexed, IMPACT FACTOR 2.971).

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52. Kirnpal-Kaur BS, Hern-Tze Tan, Boukraa L & Siew Hua Gan

(2011). Different solid phase extraction fractions of Tualang honey demonstrated diverse antibacterial properties against wound and enteric bacteria. J ApiProduct & ApiMedical Sc 3(1) 59-65.

53. CS Tan, SK Hassan, NAN Mohamad, SH Gan. (2012) “Cytochrome P450 3A4 genetic polymorphisms and post-operative fentanyl requirements”. J Clin Pharm Therap 37, 100-104 (IMPACT FACTOR 1.67, ISI-indexed) doi:10.1111/j.1365-2710.2010.01232.x

54. F Ahmad, NAC Hamzah, N Mustaffa & SH Gan. (2011)

CYP3A4*18 Polymorphisms and Anti-Hepatitis A Virus Seroprevalence. Hepato-Gastroenterology 58 (110-111), 1-13 (IMPACT FACTOR 0.67, ISI-indexed).

55. Muhamad F, Che Hamzah A, Mustaffa N & SHGan (2011). Anti-

Hepatitis A Virus Seroprevalence Among Chronic Viral Hepatitis B And C Liver Disease Patients In The North-Eastern Coast Of Peninsular Malaysia. World Journal of Gastroenterology 17(27), 1-5 (IMPACT FACTOR 2.092) (ISI-indexed).

56. Ahmad F, Che Hamzah NA, Mustaffa N & SH Gan (2011). "No

Association Exists Between CYP3A4 Polymorphisms With Anti-Hepatitis A Virus Seroprevalence Among Chronic Viral Hepatitis B & C Liver Disease Patients. HUGO Journal 5: 278. Springer.

57. M I Khalil, N Alam, M Moniruzzaman, S A Sulaiman, S H Gan.

(2011) Phenolic Acid Composition and Antioxidant Properties of Malaysian Honeys. J Food Sc. 76(6), 921-7. (IMPACT FACTOR 1.601) (ISI-indexed).

58. M. Moniruzzaman, M I Khalil, S A Sulaiman, S H Gan (2012).

Advances In The Analytical Methods For Determining The Antioxidant Properties Of Honey: A Review. Afr J Tradit Complement Altern Med. (2012) 9(1): 27-42. (IMPACT FACTOR 0.457) (ISI-indexed).

59. N Alam, M Hossain, M I Khalil, M Moniruzzaman, S A Sulaiman, S

H Gan. (2011) High concentrations of catechin detected in Withania somnifera (Ashwagandha) by HPLC analysis. BMC complementary & alternative medicine (11) 65, 1-8. (IMPACT FACTOR 2.20) (ISI-indexed).

60. Tan KL, Hassan R, Ankathil R, Baba AA, Gan SH (2011). Determination of imatinib mesylate (GleevecTM) and CGP 74588 in serum samples using ultra-high performance liquid chromatography. Ther Drug Monit 33(4), 546-547 (ISI-indexed, IMPACT FACTOR 3.127).

61. Wardah Yusof

and Gan Siew Hua (2011). Gene, ethnic and gender

influences predisposition of adverse drug reactions to artesunate among Malaysians. Toxicology Mechanisms & Methods, 1-9. (IMPACT FACTOR 0.844) (ISI-indexed).

62. Nurul Syazana Mohamad Shah, Ahmad Sukari Halim, Gan Siew

Hua & Shaharum S. Antiproliferative Effect of Methanolic Extraction of Tualang Honey on Human Keloid Fibroblasts. BMC complementary & alternative medicine, 11 (82), 1-8 (IMPACT FACTOR 2.20, ISI-indexed).

63. Ka Liong Tan, Ravindran Ankathil

and Siew Hua Gan (2011).

Method development and validation for the simultaneous determination of Imatinib Mesylate and N-desmethyl using Rapid Resolution High Performance Liquid Chromatography coupled with UV-detection. J Chromatography B 879 (30): 3583-3591 (ISI-indexed, IMPACT FACTOR 2.971).

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64. Keat Wei Loo and Siew Hua Gan (2012). Burden of Stroke in Malaysia. International J of Stroke 7, 165-167 DOI: 10.1111/j.1747-4949.2011.00767.x (IMPACT FACTOR 3.125, ISI-indexed).

65. Ruzilawati Abu Bakar, Mohd Suhaimi Ab Wahab, Imran Ahmad & Gan Siew Hua (2011). Association between sex differences and the pharmacokinetics of repaglinide among a Malaysian population. Pharmacology & Pharmacy (2), 322-327.

66. Nadia Alam, Monzur Hossain, Md. Ibrahim Khalil, Mohammed Moniruzzaman, Siti Amrah Sulaiman, Gan Siew Hua.

.(2012).

Recent advances in medicinal properties of Withania somnifera and its potential role in health benefits. Phytochemistry reviews 11:97–112 (DOI 10.1007/s11101-011-9221-5) (IMPACT FACTOR 4.333, ISI-indexed).

67. M.M. Shaik, KW Loo and Siew Hua Gan

(2012). Burden of Stroke

in Nepal. International J of Stroke 7, 517-520 DOI: 10.1111/j.1747-4949.2012.00799.x (IMPACT FACTOR 3.125, ISI-indexed).

68. Keat Wei Loo and Siew Hua Gan

(2012). Burden of Stroke in the

Phillipines. International J of Stroke 8, 131-134. doi: 10.1111/j.1747-4949.2012.00806.x (IMPACT FACTOR 3.125, ISI-indexed).

69. Chua YA, Abdullah WZ and Gan SH (2012). Development of a

High Performance Liquid Chromatography method coupled with ultraviolet detector for the detection of warfarin in human plasma. Turkish J Med Sc 42 (5): 930-941 (IMPACT FACTOR 0.21).

70. Md. Ibrahim Khalil, Siti Amrah Sulaiman, Nadia Alam, Mohammed

Moniruzzaman, Saringat Bai’e, Che Nin Man, Syed Mohsin Sahil Jamalullail and Siew Hua Gan. (2012) Gamma irradiation Increases the Antioxidant Properties of Tualang Honey Stored under Different Conditions. Molecules 17: 674-687. (IMPACT FACTOR 1.98, ISI-indexed).

71. Wan Rosli W. I., Rohana, A. J., Gan, S.H., Noor Fadzlina, H.,

Rosliza, H., Helmy, H. Mohd Nazri, S., Mohd Ismail, I., Shaiful Bahri, I., Wan Mohamad, W.B. & Kamarul Imran, M. (2012). Lipid Content and EPA and DHA levels of Selected Marine, Freshwater Fish and Shellfish Species from the East Coast of Peninsular Malaysia. Int. Journal of Food Research 19 (3): 815-821 (Scopus-Indexed).

72. Buhari S., Kalthum H, Goh Y.M., Noordin M.M., Chen H.C. & Gan S.H. (2012) Effects of tramadol on liver and renal biochemistry and histopathology in dogs undergoing surgery under pentobarbitone anesthesia. Journal of Animal and Veterinary Advances, 11 (8): 1188-94 (IMPACT FACTOR 0.292, ISI-indexed).

73. Md Ibrahim Khalil, Siti Amrah Sulaiman, Nadia Alam, Norzihana

Ramli, Mahaneem Mohamed, Saringat Bai’e, Gan Siew Hua. Content And Antioxidant Capacity Of Processed Tualang Honey (Agromas, Malaysia) Collected From Different Regions in Malaysia, International Journal of Pharmacy and Pharmaceutical Sciences, 4(3), 214-219 (IMPACT FACTOR 0.38, Scopus).

74. Keat Wei Loo and Siew Hua Gan (2012). Burden of stroke in

Cambodia 8 (475-8) International J of Stroke DOI: 10.1111/j.1747-4949.2012.00868.x (IMPACT FACTOR 3.125, ISI-indexed).

75. AB Ruzilawati, AWM Suhaimi, A Imran, SHGan (2012) "Population pharmacokinetic modelling of repaglinide in healthy Malaysian volunteers with application of the NPAG algorithm" Journal of Pharmacological Sciences 1(18) S1: 82. (IMPACT FACTOR 2.26, ISI-indexed).

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76. Alamgir Z. Chowdhury, Selina Akhter, M. Nazrul Islam, M. Khorshed Alam, M. A. Zaman, Nurul Karim, M Moniruzzaman and Gan SH. (2012) Occurrence of Organophosphorous and Carbamate Pesticides Residues In Surface Water Samples of the Rangpur District of Bangladesh. Bulletin of Environmental Contamination & Toxicology 89: 202-207 (IMPACT FACTOR 1.139, ISI-indexed).

77. Md. Nazmul Islam, Mohammed Moniruzzaman, Md. Ibrahim Khalil, Rehana Basri, Mohammad Khursheed Alam, Keat Wei Loo and Siew Hua Gan (2012). Burden of stroke in Bangladesh. International J of Stroke 8, 211-213. DOI: 10.1111/j.1747-4949.2012.00885.x (IMPACT FACTOR 3.125, ISI-indexed).

78. Keat Wei Loo & Siew Hua Gan (2012). Burden of Stroke in Laos.

International J of Stroke 8, 273–275 DOI: 10.1111/j.1747-4949.2012.00884.x (IMPACT FACTOR 3.125, ISI-indexed).

79. Buhari S., Kalthum H., Goh Y.M., Noordin M.M. & Gan S.H.

Subcutaneous Administration of Tramadol after Elective Surgery Is as Effective as Intravenous Administration in Relieving Acute Pain and Inflammation in Dogs. The Scientific World Journal (IMPACT FACTOR 1.524, ISI-indexed). Vol 2012, Article ID 564939, doi:10.1100/2012/564939

80. Keat Wei Loo, Lyn Robyn Griffiths, Siew Hua Gan. A novel multiplex PCR-RFLP method for simultaneous detection of MTHFR 677C>T, eNOS +894G>T and -786T>C variants among Malaysian Malays. BMC Medical Genetics 2012, 13:34 doi:10.1186/1471-2350-13-34 (IMPACT FACTOR 2.33, ISI-indexed).

81. Keat Wei Loo and Siew Hua Gan

(2012). Folic Acid

Supplementation is not the sole factor in determining neural tube defects: The possible role of autoantibodies (2012) African J Biotech 11 (5): 11767-71. (IMPACT FACTOR 0.573, ISI-indexed).

82. Mohammad Abdur Rahman, Alamgir Zaman Chowdhury, Mohammed Moniruzzaman, Siew Hua Gan, Mohammad Nazrul Islam, Zeenath Fardous and Mohammad Khorshed Alam (2012). Pesticide residues in tobacco leaves from the Kushtia district in Bangladesh. Bulletin of Environmental Contamination & Toxicology 89: 658-663 (IMPACT FACTOR 1.139, ISI-indexed).

83. Md. Alamgir Zaman Chowdhury, Sanjoy Banik, Borhan Uddin, Mohammed Moniruzzaman, Nurul Karim & Siew Hua Gan (2012). Organophosphorus and carbamate pesticide residues detected in water samples collected from paddy and vegetable fields of the Savar and Dhamrai Upazilas in Bangladesh. Int. J. Environ. Res. Public Health 9, 3318-29 (IMPACT FACTOR 1.605, ISI-indexed).

84. Md Ibrahim Khalil, Md. Moniruzzaman, Laid Bukhara, Md. Asiful Islam, Md. Nazmul Islam, Siti Amrah Sulaiman, Gan Siew Hua. (2012) Physicochemical status of Algerian honeys and its high antioxidants potency. Molecules 17, 11199-11215. (IMPACT FACTOR 2.386, ISI-indexed).

85. M. Moniruzzaman, B Rokeya, S Ahmed, M I Khalil, S H Gan (2012). In vitro antioxidant effects of aloe barbadensis Miller extracts & the potential role of these extracts as antidiabetic and antilipidemic agents on streptozocin-induced type 2 diabetic model rats. Molecules 12851-67 doi: 10.3390/molecules171112851 (IMPACT FACTOR 2.386, ISI-indexed).

86. Nadia Alam, Monzur Hossain, Md. Abdul Mottalib, Siti Amrah

Sulaiman, Gan Siew Hua, Md. Ibrahim Khalil. (2012). Methanolic extract of Withania somnifera roots, fruits and leaves have potential antioxidant and antibacterial properties. BMC Complementary & Alt Med 12 (175) doi:10.1186/1472-6882-12-175 (IMPACT FACTOR

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2.24, ISI-indexed).

87. Md. Asiful Islam, Md. Ibrahim Khalil, Md. Nazmul Islam,

Mohammed Moniruzzaman, Md. Abdul Mottalib4, Siti Amrah

Sulaiman, Gan Siew Hua (2012). Physicochemical and antioxidant properties of Bangladeshi honeys stored for more than one year BMC Complementary & Alt Med 12 (7) doi:10.1186/1472-6882-12-177 (IMPACT FACTOR 2.24, ISI-indexed).

88. Alamgir Zaman Chowdhury, Mohammad Nazrul Islam, Mohammed Moniruzzaman, Siew Hua Gan and Mohammad Khorshed Alam (2013). Organochlorine Insecticide Residues are found in Surface, Irrigated Water Samples from Several Districts in Bangladesh. Bulletin of Environmental Contamination & Toxicology 90(2), 149-154 (IMPACT FACTOR 1.018, ISI-indexed).

89. Keat Wei Loo & SH Gan (2012). Commentaries on “rehabilitation for patients after stroke in a tertiary hospital: is it early and intensive enough? Int J of Therapy & Rehabilitation, 19(11), 611 (Scopus-Indexed).

90. K.L. Tan, S.H.Gan, R.Hassan, A.D. Abdullah, A.Husin, A A Baba & R.Ankathil (2012). Influence of CYP1A2, CYP3A5 and CYP2C19 polymorphisms on imatinib mesylate drug responses in three major Asian ethnic groups and variation of imatinib and active metabolite (M1) trough level among chronic myeloid leukemia patients. Annals Oncology (23)11, 133-134. (IMPACT FACTOR: 6.425; ISI-indexed).

91. Nurul Syazana Ms, SH Gan, Halim AS (2013). “Gas Chromatography Mass Spectrometry Analysis Of Volatile Compounds Of Malaysian Tualang (Koompassia Excelsa) Honey”. African J Trad Compl, 10 (2), 180-88 (IMPACT FACTOR 0.7, ISI-indexed).

92. Munvar Miya Shaik & Gan Siew Hua (2013). Rapid resolution liquid

chromatography method development and validation for simultaneous determination of homocysteine, vitamins B6, B9 and B12 in human serum. Indian J Pharmacol 45(2) 45-54 (IMPACT FACTOR 0.727, ISI-indexed).

93. Buhari S, Kalthum H, Goh YM & SH Gan. (2013) The influence of surgery on tramadol’s pharmacokinetic following intravenous administration in dogs. Asian Journal of Animal and Veterinary Advances DOI 10.3923/ajava.2013 (IMPACT FACTOR 0.869, ISI-indexed).

94. Mohammed Moniruzzaman, Md. Ibrahim Khalil, Siti Amrah

Sulaiman, Siew Hua Gan (2013). Physicochemical and antioxidant properties of Malaysian honeys produced by Apis cerana, Apis dorsata and Apis mellifera: antioxidant properties of Malaysian honeys. BMC Complementary Alt Med 13:43 (IMPACT FACTOR 2.24, ISI-indexed) http://www.biomedcentral.com/1472-6882/13/43

95. Rehana Basri, Munvar Miya Shaik, Mohammad Khursheed Alam,

Md Badrul Alam Mondol, Quazi Deen Mohammad, Siew Hua Gan (2013). Waist to hip ratio, waist to height ratio and body mass index predict stroke risk in a Bangladeshi population. International Medical Journal 20(6):740-743 (IMPACT FACTOR 0.2, ISI-indexed).

96. Pasupuleti Visweswara Rao, K. Madhavi, M. Dhananjaya Naidu, Siew Hua Gan (2013). Effects of Rhinacanthus nasutus on cytosolic and mitochondrial enzymes in streptozotocin-induced diabetic rats. Evidence-Based Complementary and Alternative Medicine (ISI-indexed, IMPACT FACTOR 4.744). Article ID 486047, http://dx.doi.org/10.1155/2013/486047

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97. M. Alamgir Zaman Chowdhury, A.N.M. Fakhruddin, Md. Nazrul Islam, Mohammed Moniruzzaman, Siew Hua Gan & Md. Khorshed Alam (2013). Detection of the residues of nineteen pesticides in fresh vegetable samples using gas chromatography-mass spectrometry. Food control 34, 457-465 (IMPACT FACTOR 2.6, ISI-indexed). DOI:http://dx.doi.org/10.1016/j.foodcont.2013.05.006

98. Seong Tan PC, Nik Mohamad NA, Gan SH (2013). Factors that influence pain intensity and fentanyl requirements after a gynecologic laparotomy. Pain Manag Nurs. 14(2):102-9. doi: 10.1016/j.pmn.2010.12.004 (IMPACT FACTOR 1.36, ISI-indexed).

99. Visweswara Rao Pasupuleti, TNVKV Prasad, Rayees Ahmad Sheikh, Satheesh Krishna Balam, Valasani Koteswara Rao, Siew Hua Gan (2013). Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral and antimicrobial studies. International journal of Nanomedicine 8, 3355-3364 (IMPACT FACTOR 3.13) (ISI-indexed).

100. Gjumrakch Aliev, Khan Shahida, Siew Hua Gan, CK Firoz, Aziz

Khan, Adel M. Abuzenadah, Warda Kamal, Mohammad Amjad Kamal, Yi Tan, Xianqin Qu & M. Reale (2014). Alzheimer Disease and Type 2 Diabetes Mellitus: The Link to Tyrosine Hydroxylase and Probable Nutritional Strategies. CNS & Neurological Disorders - Drug Targets 13 (467-477) (IMPACT FACTOR 3.81, ISI-indexed)

101. Munvar Miya Shaik, Norul Badriah Hassan, Huay Lin Tan, Shalini

Bhaskar, Siew Hua Gan (2013). Reliability and Validity of Malaysian Language Translated Version of Migraine Disability Assessment (MIDAS) Questionnaire. Cephalgia 33(11) 970-971 (IMPACT FACTOR 3.485, ISI-indexed).

102. Mohammed Moniruzzaman, Siti Amrah Sulaiman, Md. Ibrahim Khalil, Siew Hua Gan.

. Sourwood honey has higher phenolics,

flavonoids and antioxidant potentials than Manuka honey. Chemistry Central Journal 7:138 (IMPACT FACTOR 1.31, ISI-indexed). DOI: 10.1186/1752-153X-7-138

103. Almas Iqbal, Iqra Ahmad, Mohammad Hassan Khalid, Nawaz MS,

Siew Hua Gan, Mohammad A. Kamal (2013). Nanoneurotoxicity to NanoNeuroprotection Using Biological & Computational Approaches. Journal of Environmental Science and Health, Part C, 31 (3) 256-284 (IMPACT FACTOR 5.16, ISI-indexed). DOI: 10.1080/10590501.2013.829706

104. Visweswara Rao Pasupuleti, Madhavi Kondeti, Dhananjaya Naidu Malepati and Siew Hua Gan (2013). Effect of Rhinacanthus nasutus on Liver glycogen, carbohydrate total protein and liver markers Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine Article ID 102901, http://dx.doi.org/10.1155/2013/102901 (IMPACT FACTOR 4.744, ISI-indexed).

105. Md. Nazmul Islam, Md. Ibrahim Khalil, Md. Asiful Islam, Gan Siew

Hua (2013). Toxic compounds in honey. J Applied Toxicology (IMPACT FACTOR 2.597, ISI-indexed) DOI 10.1002/jat.2952.

106. Shaik, M.M., S.H. Gan, and M.A. Kamal (2014). Epigenomic

approach in understanding Alzheimer’s disease and type 2 diabetes mellitus. CNS & Neurological Disorders - Drug Targets. 13(2), 283-289 (IMPACT FACTOR 3.81, ISI-indexed).

107. M M Shaik, S Ahmad, S H Gan, A M Abuzenadah, E A Ahmad, S

Tabrez, F Ahmed, M A Kamal (2014). How Do Periodontal Infections Affect the Progression of Type 2 Diabetes and Alzheimer's Disease? CNS & Neurological Disorders - Drug Targets 13(3), 460-466 (IMPACT FACTOR 3.81, ISI-indexed).

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108. Mahmood Rasool, Arif Malik, Aamir Qazi, Ishfaq Ahmed Sheikh,

Abdul Manan, Mahmood Husain Qazi, Adeel Chaudhary, Adel M. Abuzenadah, Muhammad Asif, Mohammed Hussain Alqahtani, Siew Hua Gan, Munvar Miya Shaik & Mohammad Amjad Kamal. Current view from Alzheimer disease to Type 2 Diabetes Mellitus. CNS & Neurological Disorders - Drug Targets 13(3), 533-542. (IMPACT FACTOR 3.81, ISI-indexed)

109. Pasupuleti Visweswara Rao & Siew Hua Gan (2014).

Rhinacanthus nasutus restores the glycogen and liver functional markers in streptozotocin induced diabetic rats. Asian Pacific Journal of Tropical Diseases (IMPACT FACTOR 0.6, Scopus-

indexed).

110. P.Visweswara Rao, T.Vijayakanth, Mohammed Moniruzzaman, Y.J.Sugunakar, B. Kavitha, K. Vijaya Raju, Syed Faseehunnisa, M.J.Sukhesh, Gan SH (2013). Phytochemical analysis, antibacterial, antifungal and antioxidant activities of roots, stems and leaves of Hemidesmus indicus, Ocimum sanctum and Tinospora cordifolia. Int J Pharmacology 9 (5): 277-287 (IMPACT FACTOR 1.5, ISI-indexed).

111. Mohammed Moniruzzaman, Siti Amrah Sulaiman, Siti Amirah Binti Mohd Azlan, Siew Hua Gan (2013). Seasonal Variations of Phenolics, Flavonoids and Antioxidant Content of Malaysian Acacia Honey. Molecules 2013, 18, 14694-14710; doi:10.3390/molecules181214694 (IMPACT FACTOR 2.386, ISI-indexed).

112. Ahmed F, Juned Asghar Ansari, Zahid Eqbal Ansari, Qamre Alam, Siew Hua Gan,

Mohammad A. Kamal and Ejaj Ahmad (2014). A

Molecular Bridge: Connecting Type 2 Diabetes and Alzheimer’s disease. CNS & Neurological Disorders - Drug Targets, 13(2), 312-321. (IMPACT FACTOR 3.81, ISI-indexed)

113. Jabir NR, Mohammad A. Kamal, Adel Mohammad Abuzenadah, Siew Hua Gan, Mohammed Nabil Alama, Saleh S. Baeesa, Shams Tabrez (2014). Alzheimer’s and Type 2 diabetes treatment via common enzyme targeting. CNS & Neurological Disorders - Drug Targets, 13, 299-304 (IMPACT FACTOR 3.81, ISI-indexed).

114. Dar TA, Ishfaq A. Sheikh, Showkat A. Ganie, Riyasat Ali, Laishram R. Singh, Siew Hua Gan, Mohammad A. Kamal and Mohammad A. Zargar (2014). Molecular linkages between Diabetes and Alzheimer's disease: Current scenario and future prospects. CNS & Neurological Disorders - Drug Targets, 13(2), 290-298 (IMPACT FACTOR 3.81, ISI-indexed).

115. Nedjadi T, Absarul Haque, Qamre Alam, Siew Hua Gan, Adeel G. Chaudhary, Adel M. Abuzenadah, Ghazi A. Damanhouri, Mohammad A Kamal (2014). Genomic linkage between Alzheimer's disease and type 2 diabetes. CNS & Neurological Disorders - Drug Targets, 13(2), 203-212 (IMPACT FACTOR 3.81,

ISI-indexed).

116. Qamre Alam,

Absarul Haque,

Mohammad ZubairAlam, Sajjad Karim, Gan SH, Mohammad Amjad Kamal, Asif Jiman-Fatani, Ghazi A. Damanhouri, Adel M Abuzenadah, Adeel G. Chaudhary (2014). Nanotechnological approach in management of Alzheimer diseases and type-2 diabetes. CNS & Neurological Disorders - Drug Targets, 13(3), 478-486 (IMPACT FACTOR 3.81, ISI-indexed).

117. Mahboobi H, Javad Golmirzaei, Gan SH and Mohammad A. Kamal (2014). Humanin: A possible linkage between Alzheimer’s Disease and Type 2 Diabetes. CNS & Neurological Disorders - Drug Targets, 13(3), 543-553 (IMPACT FACTOR 3.81, ISI-indexed).

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118. Hira Iftikhar

1, Iqra Ahmad

2, Siew Hua Gan

3, Munvar Miya Shaik

3,

Naveed Iftikhar4, Muhammad Sulaman Nawaz

2, Mohammad A

Kamal*5

(2014). Quinoline derivatives: Possible drug able targets for Class B GPCR: CGRP receptor, a cause of migraine. CNS & Neurological Disorders - Drug Targets 13(7): 1130-1139 (IMPACT FACTOR 3.81, ISI-indexed).

119. Munvar Miya Shaik, Huay Lin Tan, Kamal & Siew Hua Gan (2014). Do Folate, Vitamins B6 and B12 Play a Role in the Pathogenesis of Migraine? The Role of Pharmacoepigenomics. CNS & Neurological Disorders - Drug Targets, 13, 828-835 (IMPACT FACTOR 3.81,

ISI-indexed).

120. M. Alamgir Zaman Chowdhury, Iffat Jahan, Nurul Karim, ANM Fakhruddin, Md. Abdur Rahman, M. Moniruzzaman, Gan SH and Md. Khorshed Alam

.. Determination of carbamate and

organophosphorus pesticides in vegetable samples and their removal by radiation treatment. Biomed Res Int (IMPACT FACTOR 2.436) http://dx.doi.org/10.1155/2014/145159

121. Nasimudeen R. Jabir, Shams Tabrez, C. K. Firoz, Syed Kashif Zaidi, Saleh S. Baeesa, Siew Hua Gan, Ghazi A. Damanhouri, Mohammad Amjad Kamal (2015). A synopsis on nano-technological approaches towards anti-epilepsy therapy: present and future research implications. Current Drug metabolism, 16(6), 336-345 (IMPACT FACTOR 4.405, ISI-indexed). DOI: 10.2174/1389200215666141125142605

122. Mahmood Rasool, Javed Iqbal, Arif Malik, Hafiza Sobia Ramzan, Saeed Qureshi, Muhammad Asif, Mahmood Husain Qazi, Mohammad Amjad Kamal, Adeel Gulzar Ahmed Chaudhary, Mohammed Hussain Al-Qahtani, Siew Hua Gan & Sajjad Karim (2014). Hepatoprotective effects of Silybum Marianum (Silymarin) and Glycyrrhiza Glabra (Glycyrrhizin) in Combination: A Possible Synergy. Special Issue of Evidence-Based Complementary Alternative Medicine ISI-indexed, IMPACT FACTOR 1.72) Article

ID 641597, http://dx.doi.org/10.1155/2014/641597

123. Yung An Chua, Wan Zaidah Abdullah, Zurkurnai Yusof, Siew Hua Gan. A new nested allele-specific multiplex polymerase chain reaction method for detection and haplotyping of VKORC1 gene in a Malay population. Biomed Res Int (IMPACT FACTOR 2.88, ISI-indexed) http://dx.doi.org/10.1155/2014/316310

124. Keat Wei Loo, Lyn Robyn Griffiths & Siew Hua Gan (2014). Impact

of MTHFR Promoter in Mediating Fasting Blood Glucose and Serum Vitamin Profiles among Diabetics: An Epigenetic Profiling Study. Diabetes journal (ISI-indexed, IMPACT FACTOR 8.3).

125. Md. Abdul Mottalib, Tanvira Afroze Sultana, Md. Ibrahim Khalil, Siew Hua Gan, Md. Sirazul Islam, Subhagata Choudhury & M Anwar Hossain (2014). Phase Distribution of Chronic Myeloid Leukemia in Bangladesh. BMC Res notes 7; 142 (ISI-indexed, IMPACT FACTOR 1.39) http://www.biomedcentral.com/1756-0500/7/142

126. Mahmood Rasool, Sana Rashid, Mahwish Arooj, Khalid Mahmud Khan, Arif Malik, Sara Zahid, Abdul Manan, Muhammad Asif, Zarish Razzaq, Sadia Ashraf,

Mahmood Husain Qazi, Adil

Abuzenadah, Mohammed Hussain Alqahtani, Siew Hua Gan, Mohammad Amjad Kamal, Ishfaq Ahmed Sheikh (2014). New Possibilities To Treat Hepatocellular Carcinoma. Anticancer res 34: 1563-1572 (IMPACT FACTOR 1.725, Scopus-indexed).

127. Pasupuleti Visweswara Rao & Siew Hua Gan (2014). Cinnamon: A multifaceted medicinal plant. Evidence-Based Complementary Alternative Medicine (ISI-indexed, IMPACT FACTOR 1.72) Article

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ID 642942, http://dx.doi.org/10.1155/2014/642942

128. Keat Wei LOO, Lyn GRIFFITHS, Siew Hua GAN (2014). A Sweet Promise among Malaysians. Diabetes in Malaysia. Diabetes journal (ISI-indexed, IMPACT FACTOR 2.939) DOI: 10.1111/1753-

0407.12151

129. Mohammad Mijanur Rahman, Siew Hua Gan, Ibrahim Khalil (2014). Neurological effects of honey and polyphenols: current and future prospects. Special Issue of Evidence-Based Complementary Alternative Medicine: Medicinal Plants in Management of Type 2 Diabetes and Neurodegenerative Disorders (ISI-indexed, IMPACT FACTOR 1.72) Article ID 958721,

http://dx.doi.org/10.1155/2014/958721

130. Mahmood Rasool1, Arif Malik

2, Muhammad Saeed Qureshi

3, Abdul

Manan2, Peter Natesan Pushparaj

1, Muhammad Asif

4, Mahmood

Husain Qazi5, Aamer Qazi

6, Mohammad Amjad Kamal

7, Siew Hua

Gan8, *

, Ishfaq Ahmed Sheikh (2014). Recent updates in the treatment of neurodegenerative disorders using natural compounds. Special Issue of Evidence-Based Complementary Alternative Medicine: Medicinal Plants in Management of Type 2 Diabetes and Neurodegenerative Disorders (ISI-indexed, IMPACT FACTOR 1.72) Article ID 979730; http://dx.doi.org/10.1155/2014/979730.

131. Mahmood Rasool, Arif Malik, Shakeel Ahmed Ansari, Ishfaq Ahmed Sheikh, Abdul Manan, Aamir Qazi, Mahmood Husain Qazi, Adeel Chaudhary, Mohammed Hussain Alqahtani, Siew Hua Gan

and Mohammad Amjad Kamal. (2015). Nanoparticle-Based Approach Towards Management Of Various Disorders In Genomics. SI of Current Drug Metabolism 16(5): 354-361. (ISI-indexed, IMPACT FACTOR 4.4) DOI: 10.2174/1389200216666141208152121

132. Mohammed Moniruzzaman, M. Alamgir Zaman Chowdhury, Mohammad Abdur Rahman, Siti Amrah Sulaiman, Siew Hua Gan (2014). Determination of Minerals, Trace elements and Pesticides Levels in Honey samples Originating from Different Regions of Malaysia when compared to Manuka honey. Biomed Res Int (ISI-indexed, IMPACT FACTOR 2.88)

http://dx.doi.org/10.1155/2014/359890

133. Pasupuleti Visweswara Rao & Siew Hua Gan (2015). Recent advancements in diabetic treatment by using nanotechnology. Special Issue of Current Drug metabolism 16(5): 371-375 (IMPACT FACTOR 4.405, ISI-indexed) DOI: 10.2174/1389200215666141125120215

134. Keat Wei Loo & Siew Hua Gan (2014). What is the origin of the “Melayu-Kelantan”? Genetics, Historical and Linguistic Point of View on the Origin of the Kelantanese Malays Gene 545: 1–4 (IMPACT FACTOR 2.196, ISI-indexed)

http://dx.doi.org/10.1016/j.gene.2014.05.016

135. Ashraf Ali, Ishfaq Ahmed Sheikh, Zeenat Mirza, Siew Hua Gan, Mohammad Amjad Kamal, Adel M. Abuzenadah, Adeel G. A. Chaudhary, Ghazi A. Damanhouri, Ghulam Md Ashraf (2015). Application of proteomic tools in modern nanotechnological approaches towards the effective management of neurodegenerative disorders. Special Issue of Current Drug metabolism 16(5) 376-388 (IMPACT FACTOR 4.405, ISI-indexed) DOI: 10.2174/1389200216666141208153303

136. Mohammed Moniruzzaman, Pasupuleti Visweswara Rao, Chua Yung An, Md. Md. Nurul Islam Hawlader, Siti Amirah Binti Mohd Azlan, Siti Amrah Sulaiman, Siew Hua Gan (2014). Identification of Phenolic and Flavonoids Compounds in Monofloral Honeys from

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Bangladesh by High Performance Liquid Chromatography: Determination of Antioxidant Capacity. Biomed Res Int (IMPACT FACTOR 2.88, ISI-indexed) http://dx.doi.org/10.1155/2014/737490

137. Naveed Ahmad Fazili, Aabgeena Naeem, Ghulam Md Ashraf, Gan SH, Mohammad A. Kamal (2015). Therapeutic Interventions for the Eradication of Alzheimer’s disease (AD): Quest for a Remedy. CNS & Neurological Disorders - Drug Targets 16(5): 346-353 (IMPACT FACTOR 3.81, ISI-indexed) DOI:

10.2174/1389200215999141125115749

138. M. Moniruzzaman, I. Rodríguez, M. Ramil, R. Cela, S.A. Sulaiman, S.H. Gan (2014). Assessment of gas chromatography time-of-flight accurate mass spectrometry for identification of volatile and semi-volatile compounds in honey. Talanta 129: 505-515 (IMPACT FACTOR 3.498, ISI-indexed) 10.1016/j.talanta.2014.06.019

139. Munvar Miya Shaik, Norul Badriah Hassan, Huay Lin Tan, Shalini Bhaskar & Siew Hua Gan (2014). Validity and reliability of the Bahasa Melayu version of the Migraine Disability Assessment (MIDAS) Questionnaire. Biomed Res Int (IMPACT FACTOR 2.88,

ISI-indexed) http://dx.doi.org/10.1155/2014/435856

140. Nur Iwani Abd Rozak, Imran Ahmad, Harmy Mohd Yusuff, Siew

Hua Gan & Ruzilawati Abu Bakar. Serotonin Transporter (5-

HTTLPR) and Serotonin Receptor (5HT2A) Gene Polymorphisms Do Not Influence Smoking Behavior in Malaysian Males (2014). Scientia Pharmaceutica (IMPACT FACTOR 1.08; Scopus-indexed) doi:10.3797/scipharm.1406-01

141. Murtala Abu Bakar, Keat Wei Loo & Siew Hua Gan (2014). The influence of Genetic Polymorphisms on Therapeutic Efficacy and Side Effects of Anastrozole: Special Focus on Post-menopausal Breast Cancer Patients. Pharmacogenetics and Genomics (IMPACT FACTOR 3.45; ISI-indexed) 24:575–581, doi: 10.1097/FPC.0000000000000092

142. Keat Wei Loo, Lyn Griffiths, Heidi Sutherland, Emily Camilleri. Larisa Haupt, Siew Hua Gan (2014). Computational Epigenetics Profilling of CpG Islets in MTHFR. Mol Bio Report (IMPACT FACTOR 1.958; ISI-indexed) DOI 10.1007/s11033-014-3729-x

143. M. Moniruzzaman, I. Rodríguez, T. Rodríguez-Cabo, R. Cela, S.A. Sulaiman & S.H. Gan (2014). Optimization and evaluation of dispersive liquid-liquid microextraction for gas chromatography time-of-flight mass spectrometry characterization of honey samples. J Chromatography A 1368: 26-36 (IMPACT FACTOR 4.258; ISI-indexed).

144. Fahmida Alam, Md. Asiful Islam, Siew Hua Gan & Md. Ibrahim Khalil (2014). Honey: A Potential Therapeutic Agent for Managing Diabetic Wounds. Evidence Based Comp. Alt. Med (IMPACT FACTOR 2.064; ISI-indexed)

http://dx.doi.org/10.1155/2014/169130

145. MM Shaik, NB Hassan, HL Tan, SH Gan (2014). The migraine disability assessment (MIDAS) questionnaire: translation, validation and reliability of Bahasa Melayu version. Journal of Headache and Pain 2014, 15 (Suppl 1): D56 http://www.thejournalofheadacheandpain.com/content/15/S1/D56 (IMPACT FACTOR 3.281, ISI-INDEXED).

146. Rizwana Afroz, E. M. Tanvir, Fuad Hossain, Siew Hua Gan, Md. Ibrahim Khalil (2014). Protective effect of Sundarban honey against acetaminophen-induced acute hepatonephrotoxicity in rats. Special issue on "Phytomedicines against Liver Diseases: Prospects and Challenges" of Evidence Based Com. Alt. Med. (IMPACT FACTOR

2.064; ISI-indexed) http://dx.doi.org/10.1155/2014/143782

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147. Rizwana Afroz, E. M. Tanvir, Md. Asiful Islam, Siew Hua Gan, Md.

Ibrahim Khalil (2014). Antioxidant and antimicrobial potentials of a popular jujube fruit: Apple kul (Zizyphus mauritiana). J Food Biochemistry doi:10.1111/jfbc.12100 (IMPACT FACTOR 0.85; ISI-

indexed).

148. EM Tanvir, Rizwana Afroz, Md. Abdul Mottalib, Md. Ibrahim Hossain, Md. Asiful Islam, Siew Hua Gan, Md. Ibrahim Khalil (2013). Antioxidant and antimicrobial potential of BAU kul (Zizyphus mauritiana): A newly improved variety of Bangladeshi kul. J Food Biochemistry (IMPACT FACTOR 0.85; ISI-indexed) doi:10.1111/jfbc.12109

149. Siew Hua Gan, Visweswara Rao Pasupuleti, Md. Ibrahim Khalil, Gjumrakch Aliev, Marcelo M. S. Lima & Mohammad A. Kamal (2015). Medicinal Plants in Management of Type 2 Diabetes and Neurodegenerative Disorders: Editorial. Evidence Based Com. Alt. Med. (IMPACT FACTOR 2.064; ISI-indexed) Volume 2015, Article ID 686872, http://dx.doi.org/10.1155/2015/686872

150. Yung An Chua, Wan Zaidah Abdullah, Zurkurnai Yusof, Siew Hua Gan (2014). VKORC1 and CYP2C9 genotypic data-aided dose prediction alone do not accurately predict warfarin dose requirement among Asians. Turkish J Med Sc (IMPACT FACTOR

0.841; ISI-indexed) doi:10.3906/sag-1408-51

151. Sajjad Karim, Zeenat Mirza, Mohammad Amjad Kamal, Adel Mohammed Abuzenadah, Esam Ibraheem Azhar, Mohammed Hussain Al-Qahtani, Ghazi A Damanhouri, Fahim Ahmad

5, Siew

Hua Gan6 & Sayed Sartaj Sohrab (2014). The Role of Viruses on

Neurodegenerative and Neurobehavioral Diseases. CNS Drug Targets (13) 1213-1223 (IMPACT FACTOR 3.81; ISI-indexed).

152. Abuzar Elnager, Rosline Hassan, Zamzuri Idris, Zulkifli Mustafa, Wan-Arfah Nadiah, Sulaiman S. A, Siew Hua Gan,

*Wan Zaidah

Abdullah (2014). Dose dependent effect of caffeic acid phenethyl ester (CAPE) on fibrinolytic activity using human blood clot by in vitro assays. Biomed Res Int (IMPACT FACTOR 2.71; ISI-indexed) http://dx.doi.org/10.1155/2015/627471

153. Fatemeh Hayati, Amjed Hazim, Teguh Haryo Sasongko, Gan Siew Hua, Wan Mohd Izani Wan Mohamed, Juhaida Daud, Nik Soriani Yaacob, Wan Mohamad Wan Bebakar

(2014). Efficacy and safety

of sitagliptin as a third agent in the treatment of type 2 diabetes mellitus. Journal of Diabetes Research & Clinical Metabolism. doi: 10.7243/2050-0866-3-10 (Scopus-indexed).

154. Shaik Munvar M., Tan Huay L., Gan Siew H. (2014). Lower Vitamin B6 Levels Are Associated with Inflammation Among Migraine Patients. Neuroepidemiology 43:92 DOI 10.1159/000369115 (IMPACT FACTOR 2.476; ISI-indexed).

155. Shaik Munvar M, Tan Huay L, Gan Siew H, Hassan Norul, Bhaskar S (2014). Factors Associated with Migraine Disability. Neuroepidemiology 43: 95, DOI 10.1159/000369115 (IMPACT FACTOR 2.476; ISI-indexed).

156. Aziz Baba, Marjanu Hikmah Elias, Anthony Zian Au, Najlaa Maddin, Siti Maziras Makhtar, Gan Siew Hua, Azlan Husin, Sarina Sulong, Rosline Hassan, and Ravindran Ankathil (2014). Integrating Molecular, Epigenetic and Pharmacogenetic Approaches in Managing Imatinib Resistance Among Malaysian Chronic Myeloid Leukemia Patients. Blood 124 (21): 3150 (IMPACT FACTOR 9.775; ISI-indexed) www.bloodjournal.org/content/124/21/3150

157. Keat Wei Loo, Lyn Griffiths, Larisa Haupt, Siew Hua Gan (2015).

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Epistasis Analysis for Folate, Cholesterol and Blood Volume Signaling Pathway Genes on Hypertensives. J of Human Hypertension (IMPACT FACTOR 2.8, ISI-indexed)

doi:10.1038/jhh.2014.53

158. Fitrien Husin, Chan Yean Yean, Siew Hua Gan, Siti Amrah Sulaiman & Rafidah Hanim Shueb (2015). The Effects of Hydrocotyle sibthorpioides Lam. Extracts on In-vitro Dengue Replication. Evid Based Compl Alt Med (IMPACT FACTOR 1.71;

ISI-indexed) http://dx.doi.org/10.1155/2015/596109

159. Keat Wei, Heidi Sutherland, Anthony Au, Emily Camilleri, Larisa Haupt, Siew Hua Gan & Lyn R Griffiths (2015). A potential epigenetic marker mediating serum folate and vitamin B12 levels contributes to the risk of ischemic stroke. Biomed Res Int Article ID 167976 http://dx.doi.org/10.1155/2015/167976 (IMPACT FACTOR 2.71; ISI-indexed)

160. Munvar Miya Shaik, Siew Hua Gan (2014). Vitamin

supplementations as possible prophylaxis agents for migraine with aura & menstrual migraine. Biomed Res Int (IMPACT FACTOR 2.71; ISI-indexed) http://dx.doi.org/10.1155/2015/469529

161. Munvar Miya Shaik, Norul Badriah Hassan, Huay Lin Tan, Shalini Bhaskar & Siew Hua Gan (2015). Validity, reliability and application of Malaysian version of Structured Migraine Interview (SMI). J headache and pain DOI 10.1186/s10194-015-0509-5 (IMPACT FACTOR 3.28; ISI-indexed).

162. Mahmood Rasool, Arif Malik, Muhammad Imran Naseer, Abdul Manan, Shakeel Ahmed Ansari, Irshad Begum, Mahmood Husain Qazi, Peter Natesan Pushparaj, Adel M Abuzenadah, Mohammed Hussein Al-Qahtani, Mohammad Amjad Kamal & Siew Hua Gan (2015). The Role of Epigenetics in Personalized Medicine: Challenges and Opportunities. BMC Medical Genomics (IMPACT FACTOR 3.91; ISI-indexed). doi:10.1186/1755-8794-8-S1-S5

163. Helmi H, Wan Rosli WI, Rohana AJ, Gan SH, Noor Fadzlina H, Rosliza H, Mohd Nazri S, Mohd Ismail I, Wan Mohamad WB, Shaiful Bahri I & Kamarul Imran M (2015). Cardiovascular risk factors among health and medical workers in the state of Kelantan, Malaysia: are they lower than the general population? Southeast Asian Journal of Tropical Medicine and Public Health 46 (2) 504-511 (IMPACT FACTOR 0.546; ISI-indexed).

164. Murtala Abubakar & Siew Hua Gan (2015). Rapid Resolution Liquid Chromatography Method Development and Validation for Detection of Anastrozole in Human Serum FASEB J April 2015 29:779.5 (IMPACT FACTOR 5.48; ISI-indexed). http://www.fasebj.org/content/29/1_Supplement/779.5.abstract?sid=1c1a6161-7965-48cd-889e-ca60e3d9b630

165. Murtala Abubakar, Venkata Murali Bhavaraju & Siew Hua Gan (2015). Factors Associated with Anastrozole-Induced Musculoskeletal Adverse Effects in Post-menopausal Breast Cancer Women: A Preliminary Report FASEB J April 2015 29:685.2 (IMPACT FACTOR 5.48; ISI-indexed). http://www.fasebj.org/content/29/1_Supplement/685.2.abstract?sid=1c1a6161-7965-48cd-889e-ca60e3d9b630

166. SH Gan (2015). Pharmacogenomics & Genetic testing in the Malaysian populations. Public Health Genomics (suppl 1): 6. (IMPACT FACTOR 2.46; ISI-indexed) DOI:10.1159/000381430

167. Ahmad Aizat AA, MD Salleh MS, Bhavaraju VMK, Andee DZ, Gan

SH, Ankathil R (2015) mRNA expression of CYP1B1 in Early Stage Malaysian Breast Cancer Patients- A Preliminary Report. Public Health Genomics (suppl 1): 16. (IMPACT FACTOR 2.46; ISI-

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indexed) DOI:10.1159/000381430

168. N. Maddin, H. Azlan, S. H. Gan & R. Ankathil (2015). Impact of CYP3A5*3 (6986A>G) Polymorphism in Imatinib Mesylate Treatment Response in Chronic Myeloid Leukemia Patients. Public Health Genomics (suppl 1): 10. (IMPACT FACTOR 2.46; ISI-indexed) DOI:10.1159/000381430

169. Tahereh Eteraf-Oskouei, Saeideh Allahyari, Arezu Akbarzadeh, Abbas Delazar, Mahdiyeh Pashaii, Siew Hua Gan, Moslem Najafi (2015). Anti-Angiogenesis Effect of Ficus carica Linn. Leaves in the Rat Air Pouch Model of Inflammation Evid Based Compl Alt Med (IMPACT FACTOR 1.71; ISI-indexed) Vol 2015, Article ID 760405,

9 pages, http://dx.doi.org/10.1155/2015/760405

170. Nusrat Jahan, Md. Asiful Islam, Fahmida Alam, Siew Hua Gan & Md. Ibrahim Khalil (2015). Regulated and prolonged heating of honey increases its antioxidant potentials but reduces antimicrobial activity. African J Traditional Comp. Med. 12(4):134-144 http://dx.doi.org/10.4314/ajtcam.v12i4.20 (IMPACT FACTOR 0.56; ISI-indexed)

171. E. M. Tanvir, Rizwana Afroz, M. Alamgir Zaman Chowdhury, Md. Ibrahim Khalil, Md. Sabir Hossain, Md. Abdur Rahman, Siew Hua Gan (2015). Honey has a protective effect against chlorpyrifos-induced toxicity on lipid peroxidation, diagnostic markers and hepatic histoarchitecture. European Journal of Integrative Medicine, IMPACT FACTOR 0.64 (Scopus-indexed) doi:10.1016/j.eujim.2015.04.004

172. Md. Ibrahim Khalil, E. M. Tanvir, Rizwana Afroz, Siti Amrah Sulaiman & Siew Hua Gan (2015). Cardioprotective Effects of Tualang Honey: Amelioration of Cholesterol and Cardiac Enzymes Levels. Biomed Res Int (IMPACT FACTOR 2.71; ISI-indexed)

http://dx.doi.org/10.1155/2015/286051

173. Mahmood Rasool, Arif Malik, Mahwish Arooj, Abdul Manan, Mahmood Husain Qazi, Mohammad Amjad Kamal, Ishfaq Ahmed Sheikh, Siew Hua Gan, Muhammad Asif and Muhammad Imran Naseer (2015). Roles of Natural Compounds from Medicinal Plants in Cancer Treatment: Structure and Mode of Action at Molecular Level. Medicinal Chemistry, (IMPACT FACTOR 1.39; ISI-indexed).

10.2174/1573406411666150430120038

174. K.W. Loo, L. Griffiths & S.H. Gan (2014). Influence of MTHFR, eNOS, ACE and ApoE haplotypes in modulating serum vitamin profiles among ischaemic stroke patients J Neurol (2014) 261 (Suppl 1):S68–S69 DOI 10.1007/s00415-014-7337-4 (IMPACT FACTOR 3.84; ISI-indexed).

175. T. Rodriguez-Cabo, M. Moniruzzaman, I. Rodriguez, M. Ramil, R. Cela & SH Gan (2015). Time-of flight accurate mass spectrometry identification of quinolone alkaloids in honey. Analytical and Bioanalytical Chemistry DOI 10.1007/s00216-015-8791-2 (IMPACT FACTOR 3.578, ISI-indexed).

176. Nur-E-Alam, M. Alamgir Zaman Chowdhury, M. Sabir Hossain, Mohammad Mijanur Rahman, M. Abdur Rahman, Siew Hua Gan and Md. Ibrahim Khalil (2015). Detection of Residual Levels and Associated Health Risks of seven pesticides in fresh eggplant and tomato samples from Narayangong District, Bangladesh. Special Issue in "Food Chemistry: Food Quality and New Analytical Approaches" J of Chemistry (IMPACT FACTOR 0.36, ISI-indexed)

http://dx.doi.org/10.1155/2015/243574

177. Loo Keat Wei, Heidi Sutherland, Anthony Au, Emily Camilleri, Larisa M Haupt, Siew Hua Gan & Lyn R Griffiths (2015). Methylenetetrahydrofolate Reductase CpG Islands: Epigenotyping.

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J of Clin Lab Analysis (IMPACT FACTOR 1.038, ISI-indexed) doi:

10.1002/jcla.21860

178. Md. Ibrahim Khalil, Md. Asiful Islam, Nadia Alam, Siew Hua Gan, Siti Amrah Sulaiman (2015). Irradiation and evaporation enhances physicochemical characteristics, AEAC, FRAP, protein and proline contents of Tualang honey. J Food biochemistry (IMPACT FACTOR 0.853, ISI-indexed) DOI: 10.1111/jfbc.12182

179. Md. Ibrahim Khalil, Istiyak Ahmed, Romana Ahmed, E. M. Tanvir, Rizwana Afroz, Sudip Paul, Siew Hua Gan & Nadia Alam (2015). Amelioration of isoproterenol-induced oxidative damage in rat myocardium by Withania somnifera leaf extract. BioMed Research International (IMPACT FACTOR 2.7, ISI-indexed). http://dx.doi.org/10.1155/2015/624159

180. Loo Keat Wei, Anthony Au, Saras Menon, Siew Hua Gan and Lyn R. Griffiths (2015). Clinical Relevance of MTHFR, eNOS, ACE, and ApoE Gene Polymorphisms and Serum Vitamin Profile among Malay Patients with Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases: pp 2017-2025 (IMPACT FACTOR

1.669, ISI-indexed).

181. Md. Asiful Islam, Fahmida Alam, Teguh H Sasongko, Azlan Husin, Sarimah Abdullah, Siew Hua Gan & Wong K Keng. Antiplatelet and anticoagulant agents for preventing recurrence of peripheral vascular thrombosis in patients with Antiphospholipid Syndrome Cochrane (IMPACT FACTOR 5.94, ISI-indexed). DOI: 10.1002/14651858.

182. E. M. Tanvir, Rizwana Afroz, M. Alamgir Zaman Chowdhury, Siew Hua Gan, Nurul Karim, Md. Nazrul Islam, Md. Ibrahim Khalil (2015). A model of chlorpyrifos distribution and its biochemical effects on the liver and kidneys of rats. Human and Experimental Toxicology (IMPACT FACTOR 1.74, ISI-indexed). DOI:10.1177/0960327115614384

183. Sudip Paul, E. M. Tanvir, Md. Aminul Islam, Md. Sakib Hossen, Rizwana Afroz, Md. Istiyak Ahmed Shaku, Moumoni Saha, Siew Hua Gan & Md. Ibrahim Khalil (2015). Antioxidant properties of Citrus macroptera fruit and its in vivo effects on the liver, kidney and pancreas in Wistar rats. Int J of Pharmacology (IMPACT FACTOR 0.71, ISI-indexed) DOI: 10.3923/ijp.2015.

184. Nadia Alam, Apurba Kumar Roy, Sudhangshu Kumar Biswas, Siew Hua Gan & Md. Ibrahim Khalil (2015). Identification of Mycoflora of Lablab Bean [Lablab purpureus (L.) Sweet] Seed Grown in Bangladesh and its Control by Hot Water Treatment (ISI-indexed, no impact factor). American-Eurasian J. Agric. & Environ. Sci., 15 (9): 1760-1766, 2015. DOI: 10.5829/idosi.aejaes.2015.15.9.966

185. Md. Solayman Naeem, Sudip Paul, Md. Asiful Islam, Yousuf Ali, Ibrahim Khalil & Siew Hua Gan (2015). Physicochemical Properties, Minerals, Trace Elements & Heavy Metals in Honey of Different Origins: An Update. Comprehensive Reviews in Food Science and Food Safety 15(1) 219-33 (IMPACT FACTOR 4.18, ISI-indexed) doi.10.1111/1541-4337.312182.

186. Md. Asiful Islam, Wong Kah Keng, Teguh Haryo Sasongko, Wong Jin Shyan, Siew Hua Gan. Familial primary antiphospholipid syndrome: A first report of co-occurrence in three family members from East Malaysia. Eu. J Rheumatology (Scopus-indexed) DOI: 10.5152/eurjrheum.2015.0068.

187. Nandita Sharkar, M. Alamgir Zaman Chowdhury, A.N.M. Fakhruddin, Zeenath Fardous, Mohammed Moniruzzaman & S H Gan (2015). Assessment of Heavy Metal Content and Physical

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Parameters of Bangladeshi Aegiceras corniculatum, Brassica juncea and Litchi chinensis Honeys. BioMed Research International (IMPACT FACTOR 1.7, ISI-indexed) http://dx.doi.org/10.1155/2015/720341

188. Md. Solayman, Yousuf Ali, Fahmida Alam, Md. Asiful Islam, Nadia Alam, Md. Ibrahim Khalil & SH Gan (2016). Polyphenols: Potential future arsenals in the treatment of Diabetes. Thematic Issue entitled “Managing strategies for diverse diseases: Challenges from bench to bedside in successful drug discovery and development. (IMPACT FACTOR 3.28, ISI-indexed). Current Pharmaceutical Design 22(5): 549-65.

189. Rizwana Afroz, E. M. Tanvir, Sudip Paul, Mahmudul Hasan, Nikhil Chandra Bhoumik, Siew Hua Gan, Md. Ibrahim Khalil (2014). Phenolic acid composition, antioxidative and DNA damage inhibition properties of Sundarban honey. J Food Biochemistry (ISI-indexed, IMPACT FACTOR 0.85) doi:10.1111/jfbc.12240

190. Naveed Ahmad Fazili, Aabgeena Naeem, Ghulam Md Ashraf, Gan SH, Mohammad A. Kamal (2015). Therapeutic Interventions for the Eradication of Alzheimer’s disease (AD): Quest for a Remedy. Current Drug Metabolism, 16: 346-53. (ISI-indexed, IMPACT FACTOR 3.8).

191. Buhari Salisu, Kalthum Hashim, Goh Yong Meng & Gan Siew Hua (2015). Gender-related differences in pharmacokinetic parameters of tramadol following intravenous and subcutaneous administration in dogs. African J Pharmacy & Pharmacology 9(42), 1002-1008. DOI: 10.5897/AJPP2015.4408 (non-indexed, IMPACT FACTOR

0.8).

192. M. Johnathan, Nurul AA, Wan Ezumi MF and Gan S.H., (2016). GC-MS analysis on on volatile compounds of Lignosus rhinoceros (tiger milk mushroom). Research Journal of Pharmaceutical, Biological and Chemical Sciences 7 (4) 5-16. (Scopus-indexed, IMPACT FACTOR 0.35).

193. Pasupuleti Visweswara Rao, Devi Nallappan, Shafiqur Rahman &

Siew Hua Gan (2016). Medicinal plants and biogenic metallic nanoparticles role as anticancer agents: An update. Oxidative Medicine and Cellular Longevity (IMPACT FACTOR 3.516, ISI-

indexed) http://dx.doi.org/10.1155/2016/3685671

194. Sudip Paul, Md. Aminul Islam, E. M. Tanvir, Rumana Ahmed, Sagarika Das, Noor-e Noushin, Mashud Parvez, Siew Hua Gan & Md. Ibrahim Khalil (2016). Citrus macroptera fruit confer protective effect against paracetamol-induced hepatorenal toxicity in male Wistar rat. Evid Based Compl Alt Med (IMPACT FACTOR 1.88; ISI-indexed) http://dx.doi.org/10.1155/2016/9470954

195. Pasupuleti Visweswara Rao, Kumarathevan, Naguib Salleh & Siew Hua Gan (2016). Biological and therapeutic effects of honey produced by honey bees and stingless bees: A comparative review. Brazilian Journal of Pharmacognosy (IMPACT FACTOR 0.84, ISI-indexed) http://dx.doi.org/10.1016/j.bjp.2016.01.012

196. Md. Harunur Rashid, Zeenath Fardous, M. Alamgir Zaman Chowdhury, Md. Khorshed Alam, Md. Latiful Bari, Mohammed Moniruzzaman and Siew Hua Gan (2016). Determination of heavy metals levels in fresh tea leaf, processed tea (black tea) and soil from tea plantations from Bangladesh: Evaluation of Six digestion methods. Chemistry Central Journal (IMPACT FACTOR 2.187; ISI-

indexed) DOI 10.1186/s13065-016-0154-3

197. Fahmida Alam, Md. Asiful Islam, Md. Ibrahim Khalil & Siew Hua Gan (2016). Intervention Approaches on Metabolic Control of Type 2 Diabetes Targeting GLUT4 Glucose Transporter. Current

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Pharmaceutical Design (IMPACT FACTOR 3.45; ISI-indexed) 22 (20): 3034-3049.

198. Md. Asiful Islam, Fahmida Alam, Md. Ibrahim Khalil, Teguh Haryo Sasongko & Siew Hua Gan (2016). Natural products towards the discovery of potential future antithrombotic drugs. Current Pharmaceutical Design (IMPACT FACTOR 3.45; ISI-indexed) 22 (20): 2926-46.

199. Mohammed Moniruzzaman, Siti Amrah Sulaiman & Siew Hua Gan (2015). Phenolic Acids and Flavonoids Composition of Malaysian Honeys. J Food biochemistry (IMPACT FACTOR 0.85; ISI-indexed). doi:10.1111/jfbc.12282

200. M. S. Hossain, A.N.M. Fakhruddin, Muhammed Alamgir Zaman Chowdhury & Siew Hua Gan (2016). Impact of Ship Breaking Activities on the Coastal Environment of Bangladesh and Management System for its Sustainability. Environmental Science & Policy 60; 84-94 (IMPACT FACTOR 3.018; ISI-indexed). doi:10.1016/j.envsci.2016.03.005

201. Md. Abu Saleh, Md. Solayman, Sudip Paul, Md. Ibrahim Khalil and S. H Gan (2016). Impacts of Non-synonymous Single Nucleotide Polymorphisms of Adiponectin Receptor 1 Gene on Corresponding Protein Stability: A Computational Approach, Biomed Res Int (IMPACT FACTOR 1.56, ISI-indexed)

http://dx.doi.org/10.1155/2016/9142190

202. Murtala B. Abubakar & Siew Hua Gan (2016). Molecular targets in advanced therapeutics of cancers: the role of pharmacogenetics. J of oncology (IMPACT FACTOR 2.422, ISI-indexed) DOI: 10.1159/000446437

203. Rizwana Afroz, E. M. Tanvir, Nurul Karim, Md. Sabir Hossain, Nadia Alam, Siew Hua Gan & Md. Ibrahim Khalil (2016). Sundarban Honey confers protection against isoproterenol-induced myocardial infarction in Wistar rats. Biomed Res Int (IMPACT FACTOR 1.56, ISI-indexed)

http://dx.doi.org/10.1155/2016/6437641

204. Fahmida Alam, Md. Asiful Islam, Siew Hua Gan, Mafauzy Mohamed, Teguh Haryo Sasongko (2016). DNA Methylation: An Epigenetic Insight into Type 2 Diabetes Mellitus Current Pharmaceutical Design (IMPACT FACTOR 3.45, ISI-indexed). Q1

205. Fahmida Alam, Md. Asiful Islam, Teguh Haryo Sasongko & Siew Hua Gan (2016). Type 2 Diabetes Mellitus and Alzheimer’s disease: Bridging the pathophysiology and management. Current Pharmaceutical Design (IMPACT FACTOR 3.45, ISI-indexed). Q1

206. Md. Asiful Islam*, Fahmida Alam, Teguh Haryo Sasongko

& Siew

Hua Gan (2016). Antiphospholipid Antibody-Mediated Thrombotic Mechanisms in Antiphospholipid syndrome: Towards Pathophysiology-Based Treatment. Current Pharmaceutical Design (IMPACT FACTOR 3.45, ISI-indexed). Q1

207. Johnathan M, Gan SH, Ezumi MF

& Nurul AA (2016). Phytochemical profiles and inhibitory effects of Tiger Milk mushroom (Lignosus rhinocerus) extract on ovalbumin-induced airway inflammation in a rodent model of asthma. BMC Comp Alt Med (IMPACT FACTOR 2.02, ISI-indexed) Q1. DOI 10.1186/s12906-016-1141-x

208. Md. Harunur Rashid, M. Alamgir Zaman Chowdhury, Zeenath Fardous, E. M. Tanvir, M. Kamruzzaman Pramanik, Israt Jahan, Md. Khorshed Alam, Mohammed Moniruzzaman & Siew Hua Gan (2016). Microbial Decontamination of Black Tea using Gamma

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Radiation and Assessment of Macronutrients in Black Tea in comparison to Fresh Tea Leaf and Soil of Tea Gardens. LWT Food Science & Tech 73 (185-190) (IMPACT FACTOR 2.41, ISI-indexed) Q1.

209. Murtala B. Abubakar & Siew Hua Gan (2016). A review of chromatographic methods used in the determination of Anastrozole Levels. Indian Journal of Pharmaceutical Sciences; 78(2):173-181 (IMPACT FACTOR 0.6, ISI-indexed) Q4.

210. Md. Solayman, Md. Asiful Islam, Fahmida Alam, Md. Ibrahim

Khalil, Mohammad Amjad Kamal & Siew Hua Gan (2016). Natural Products Combating Against Neurodegeneration: Parkinson's Disease. Current Drug Metabolism (IMPACT FACTOR 2.847, ISI-indexed).

211. Zunuraian Z, Ainaa, AR, Bhavaraju MK, Sirajudeen KNS, Wan N Arifin Wan M, Gan SH & Hamid Jan JM (2016). Anthropometric and reproductive factors among newly-diagnosed breast cancer and healthy women: a case-control study. Asian Pacific Journal of Cancer Prevention (Scopus-indexed).

Books : 1. Single author: SH Gan (2010). CYP2D6 genetic polymorphisms and tramadol’s action. 1st

ed. VDM Publishing house, Germany (ISBN 978-3-639-24115-0), published 30

th Mac, 2010, (283 Pages).

2. Book Chapter. SH Gan (2011). “Pengunaan ubat-ubatan”. In: Kesihatan

Wanita Usia Emas (Zaharah Sulaiman ed.), p. 258-277. 1st ed. Kuala

Lumpur: Dewan Bahasa & Pustaka (ISBN 978-983-46-0712-8) (337 Pages).

3. Single author: Gan Siew Hua (2015). Children’s book: “Baby Star Fly

From the Sky” (ISBN 978-967-13397-0-1) printed by Mega Harmony Sdn Berhad, June 2015 (23 Pages).

4. Tan Lee Ann & Gan Siew Hua (2015). Children’s book: “Baby Star’s Mountain Adventure” (ISBN 978-967-13397-1-8) printed by Mega Harmony Sdn Berhad, Jul 2015 (23 Pages).

5. Tan Sue Ann & Gan Siew Hua (2015). Children’s book: “Baby Star Went to the Zoo” (ISBN 978-967-13397-2-5) printed by Mega Harmony Sdn Berhad, Jul 2015 (20 Pages).

6. Tan Jo Ann & Gan Siew Hua (2015). Children’s book: “Baby Star’s New Friend” (ISBN 978-967-13397-3-2) printed by Mega Harmony Sdn Berhad, Sep 2015 (19 Pages).

7. Tan Hooi Ann & Gan Siew Hua (2015). Children’s book: “Baby Star Went to School” (ISBN 978-967-13397-4-9) printed by Mega Harmony Sdn Berhad, Sep 2015 (20 Pages).

8. Gan Siew Hua & Murtala Bello Abubakar (2016). “Taking Drugs Based on Your Genetic Makeup: The role of pharmacogenetics”. Published by Zi Publications Sdn Bhd, printed by BS print. (ISBN 978-967-0486-70-3) Jan 2016 (24 Pages).

9. Gan Siew Hua & Murtala Bello Abubakar. “Pengambilan Ubat/Drug

berdasarkan genetik anda: Peranan Farmakogenetik” (2016) Published by Zi Publications Sdn Bhd, printed by BS print. (ISBN 978-967-0486-

71-0) Jan 2016 (24 Pages).

10. Single author: Gan Siew Hua “Given another Chance. One life: Take two” (2016) by Gan Siew Hua. Published by Kanyin Publications Sdn Bhd; printed by Unipress Printer Sdn. Bhd. (ISBN 978-983-3789-93-1) Jun 2016 (193 Pages).

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11. Gan Siew Hua & Munvar Miya Shaik (2016). Book chapter entitled Epigenetics & Migraine in Neurobehavioral Disorders and Epigenetics (USA). (Yasui, Peedicayil & Grayson ed) Elsevier (in press: scheduled to publish Oct 2016).

12. Mohd Ibrahim Khalil & Gan Siew Hua (2016) Honey Composition and

Health Benefits by (eds) (UK). John, Wiley & Sons (in press: scheduled to publish Dec 2016).

Others (Copyright)

1. Registered trademark (Trademark no 2014056151) for a new product

called “BreathEzi” granted by the Intellectual Property Corporation of Malaysia under the Trademark Act for the Category of Pharmaceutical Preparations, Dietetic Substances Adapted For Medical Use; All Included In Class O5.

Achievements/Awards / Recognitions

: 1. Excellence in Pharmacy Practice Award (best overall first year pharmacy student) received from Liverpool John Moores University, 1993 for Manchester University.

2. Best POSTER PRESENTATION: Gan S. H., Ismail, R, Wan

Adnan, W. A. & Zulmi, W. Can the Visual Analogue Scale (VAS) be used to measure postoperative pain? Presented at the 15

th Scientific Meeting of the Malaysian Society of

Pharmacology and Physiology, Universiti Sains Malaysia, May 2000.

3. Best ORAL PRESENTATION: Gan S. H., Ismail, R. & Teh,

L.K. Pharmacokinetics of tramadol hydrochloride in Malay subjects of CYP2D6*10 genotype undergoing orthopaedic surgeries. Presented at the 10

th Scientific Meeting of the

Malaysian Association of Clinical Biochemists, Kuala Lumpur, August 2000.

4. Best POSTER PRESENTATION: Gan S. H., Ismail, R., Jelliffe,

RW, Wan Adnan, W. A. & Zulmi, W. "Population Pharmacokinetics Modelling of Tramadol with Application of NPEM algorithms". Presented at the First North-South Conference on Pharmacogenetics", Holiday Villa Subang Jaya, Malaysia on the 12 December, 2005.

5. BEST ORAL PRESENTATION: W R Wan Aasim, Tan SC &

Gan SH. Headspace solid-phase microextraction GC-MS of amphetamine, methamphetamine enantiomers using on-fibre chiral derivatization. 1

st National Conference on Medical

Laboratory Sciences (NaCMeLS), 8-9 November, 2006, Grandriverview Hotel, Kota Bharu.

6. Shortlisted for “Best Pre-Clinical Lecturer” Award, Citra Ilmu &

Graduation Night, Universiti Sains Malaysia, 15 May 2007.

7. Excellent Service Award 2006, received from Universiti Sains Malaysia on 25th May 2007 at Renaissence Hotel, Kota Bharu, Kelantan.

8. Hadiah Sanjungan (Merit award) 2007 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Method development and validation of repaglinide in human plasma by HPLC and its application in pharmacokinetic studies” by Abu Bakar Ruzilawati, Mohd Suhaimi Abd. Wahab, Ahmad Imran, Zabidah Ismail & Gan SH in the Journal of Pharmaceutical and Biomedical Analysis 43, 1831-1835; 2007.

9. Hadiah Sanjungan (Merit award) 2007 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Genetic polymorphisms of CYP3A4: CYP3A4*18 allele is found in five healthy Malaysian subjects” by Abu Bakar Ruzilawati, Mohd Suhaimi Abd. Wahab & Gan SH in Clin.

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Chimica Acta, 383, 158-162; 2007.

10. "Top Referee of the Year Award" (2008) as reviewer for the

journal Analytica Chimica Acta. Received on 8 January 2009 from Elsevier.

11. Hadiah Sanjungan (Merit award) 2008 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Development of a simultaneous liquid-liquid extraction and chiral derivatization method for stereospecific analysis of amphetamine-type stimulants in human urine using fractional factorial design” by Wan Raihana WA, SH Gan, S.C. Tan, Biomedical Chromatography Journal 2008 (22), 1035-1042.

12. Best research presentation Award for the year 2007/2008

(received on 23 April 2009) for a paper entitled "Pharmacokinetics & Pharmacodynamics modelling of repaglinide in Geriatric population" from Universiti Sains Malaysia.

13. Hadiah Sanjungan (Merit award) 2009 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Population pharmacokinetic modeling of repaglinide in healthy volunteers by using nonparametric adaptive grid (NPAG) algorithm” by Ruzilawati A Bakar, M Suhaimi A Wahab, SH Gan. J Clin Pharmacy 34, 1-8.

14. Hadiah Sanjungan (Merit award) 2009 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “High prevalence of CYP2A6*4 and CYP2A6*9 alleles among Malaysian population” by Wardah Y & SH Gan in Clinica Chimica Acta (403), 105-109.

15. Hadiah Sanjungan (Merit award) 2009 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers” by Navaratnam V, Ramanathan S, Wahab MS, SH Gan, Mansor SM, Kiechel JR, Vaillant M, Taylor WR, Olliaro P in Eur J Clin Pharmacol., 65(8), 809-821.

16. Hadiah Sanjungan (Merit award) 2009 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Modification of Propranolol's Bioavailability by Eurycoma Longifolia Water-Based Extract” by S A b Salman, Siti Amrah S, M S A Wahab, R Ismail, Yuen KH, Z Ismail, SH Gan published in J Clin Pharmacy Therap (34), 1-6.

17. Hadiah sanggar sanjung kategori penerbitan jurnal (2010).

"High 5-hydroxymethylfurfural concentrations are found in Malaysian honey". Food And Chemical Toxicology.

18. Hadiah sanggar sanjung kategori penerbitan jurnal (2010).

"Quantitative determination of propranolol by ultraviolet". Toxicology Mechanisms And Methods.

19. Hadiah sanggar sanjung kategori penerbitan jurnal (2010).

"HPLC method development and validation for simultaneous detection of Arabinoside-C and doxorubicin". Toxicology Mechanisms And Methods.

20. Hadiah sanggar sanjung kategori penerbitan jurnal (2010).

"Stereoselective method development and validation for determination of amphetamine-type stimulants and metabolites in human urine" J Chrom B.

21. Hadiah sanggar sanjung kategori penerbitan jurnal (2010).

"Cytochrome P450 3A4 genetic polymorphisms and post-

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operative fentanyl requirements". J Clin Pharm Therap.

22. Shortlisted for “Best Pre-Clinical Lecturer” Award, Citra Ilmu & Graduation Night, Universiti Sains Malaysia, 1 May 2011.

23. Top 4 Finalist for LCGC Emerging Leader in Chromatography

Award 2012, Pittsburgh Conference, Orlando, Florida, USA (March 12‐15, 2012).

24. Excellent Service Award 2011, received from Universiti Sains

Malaysia on 7th May 2012 at Renaissence Hotel, Kota Bharu, Kelantan.

25. Quality Publication Award (3

rd place) for publications in 2010

(individual category) received in April, 2012.

26. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains Malaysia (Journal Publication Category) for a paper entitled “The association between surgical-related variables, pain intensity and its control following gynaecological laparotomy via intravenous patient-controlled analgesia fentanyl” Pain Management Nursing.

27. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “CYP3A4*18 Polymorphisms and Anti-Hepatitis A Virus Seroprevalence”. Hepato-Gastroenterology.

28. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Anti-Hepatitis A Virus Seroprevalence Among Chronic Viral Hepatitis B And C Liver Disease Patients In The North-Eastern Coast Of Peninsular Malaysia. World Journal of Gastroenterology.

29. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Phenolic Acid Composition and Antioxidant Properties of Malaysian Honeys. J Food Sc.

30. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “High concentrations of catechin detected in Withania somnifera (Ashwagandha) by HPLC analysis. BMC complementary & alternative medicine”.

31. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Gene, ethnic and gender influences predisposition of adverse drug reactions to artesunate among Malaysians. Toxicology Mechanisms and Methods”.

32. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Antiproliferative Effect of Methanolic Extraction of Tualang Honey on Human Keloid Fibroblasts. BMC complementary & alternative medicine”.

33. Hadiah Sanjungan (Merit award) 2011 from Universiti Sains

Malaysia (Journal Publication Category) for a paper entitled “Method development and validation for the simultaneous determination of Imatinib Mesylate and N-desmethyl using Rapid Resolution High Performance Liquid Chromatography coupled with UV-detection. J Chromatography B”.

34. Anugerah Sanggar Sanjung 2012 (kategori penerbitan) bagi

penerbitan bertajuk “Recent advances in elucidating the biological properties of Withania somnifera and its potential

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role in health benefits” published in Phytochemistry Reviews (ISI-indexed, Impact factor 4.33) received on .

35. BEST ORAL PRESENTATION: Munvar Miya Shaik, Norul

Badriah Hasan, Tan Huay Lin, Siew Hua Gan. The impact of Migraine on Quality of Life (QOL) in females. 3

rd International

Public Health Conference, Kuching, Sarawak, Malaysia (27 – 29 August, 2013).

36. BEST ORAL PRESENTATION (2

nd prize): Wan Raihana W.

Aasim, S. H. Gan & S. C. Tan. Correlation Analysis And Enzyme Inhibition Of Cytochrome P450-Mediated Stereoselective Metabolism Of 3,4-Methylenedioxymethamphetamine In Human Liver Microsomes at 2

nd International Postgraduate Conference on

Pharmaceutical Sciences, 4th

-5th

Sep 2013, UITM, Shah Alam.

37. Memorandum Of Agreement (MOA) between USM and BGI Tech Solutions (Hong Kong) Co., limited (Reg no: 1841783) signed on 29 Mac 2013 for a research on “Whole Transcriptome Analysis using Next Generation Sequencing“.

38. Young Investigator Award: Keat Wei Loo, Lyn Griffiths & Siew Hua Gan (2014) for a paper entitled “Potential Impact of Genotype and Haplotype MTHFR, eNOS ACE and APOE Gene Polymorphisms on Malaysian Hypertensive Subjects".

39. Gold Medal Award for the product ‘BreathEzi (Tiger Milk

Mushroom): A Natural Remedy for the Management of Asthma’ yang dipamerkan di Pameran 25th International Invention, Innovation & Technology Exhibition 2014 (Itex 2014), 8 - 10 Mei 2014, Pusat Konvensyen Kuala Lumpur (KLCC). Awardees: Nurul Asma Abdullah, Gan SH, Wan Ezumi MF, Faezahtul AH, Wan Majdiah WM, Johnathan A/L Malagobadan.

40. Most popular article for Indian J of Pharmacology: “Munvar

Miya Shaik & Gan Siew Hua (2013). Rapid resolution liquid chromatography method development and validation for simultaneous determination of homocysteine, vitamins B6, B9

and B12 in human serum. Indian J Pharmacol 45(2) 45-54”

41. Award from Institute of Food Technologists, USA for publishing the most cited paper published in the Journal of Food Science in 2011 entitled “Phenolic Acid Composition and Antioxidant Properties of Malaysian Honeys” to be received at the New Orleans Morial Convention Center, room 253 on 22 June, 2014 5.00-6.30 pm.

42. Anugerah Sanggar Sanjung Award from Universiti Sains

Malaysia (2013) for a paper entitled “Detection of the residues of nineteen pesticides in fresh vegetable samples using gas chromatography-mass spectrometry”. Food control 34, 457-

465 DOI:http://dx.doi.org/10.1016/j.foodcont.2013.05.006

43. Anugerah Sanggar Sanjung Award from Universiti Sains Malaysia (2013) for a paper entitled “Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral and antimicrobial studies”. International journal of Nanomedicine 8, 3355-3364 (Impact factor 3.13, ISI-indexed).

44. Anugerah Sanggar Sanjung Award from Universiti Sains

Malaysia (2014) for a paper entitled “Assessment of gas chromatography time-of-flight accurate mass spectrometry for identification of volatile and semi-volatile compounds in honey”. Talanta 129: 505-515 (ISI-indexed, IMPACT FACTOR

3.498) 10.1016/j.talanta.2014.06.019

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45. Anugerah Sanggar Sanjung Award from Universiti Sains

Malaysia (2014) for a paper entitled “Optimization and evaluation of dispersive liquid-liquid microextraction for gas chromatography time-of-flight mass spectrometry characterization of honey samples”. J Chrom A 1368: 26-36 (IMPACT FACTOR 4.258; ISI-indexed).

46. Won First Place for “Quality Publication Award” PPSP, 2015

(individual category) Feb 2015.

Editor/ Editorial Board Members

1. International Board of Reviewers for Informing Science

Institute's InSITE 2006, Salford, England.

2. International Board of Reviewers for Informing Science Institute's InSITE 2008, Varna, Bulgaria.

3. International Board of Reviewers for Informing Science

Institute's InSITE 2009, Macon, Georgia.

4. Regional editor (for South East Asia region) for Electronic Physician Journal (ISSN: 2008-0913) appointment date 27 Jan 2010.

5. Editorial Committee for Proceedings from 3

rd Regional

Conference on Molecular Medicine 2009, published by INFORMM in Collaboration with Penerbit Universiti Sains Malaysia (ISBN 978-983-44297-0-6).

6. International Board of Reviewers for Informing Science

Institute's InSITE 2011, Novi Sad, Serbia.

7. International Board of Reviewers for Informing Science Institute's InSITE 2012, Montreal, Canada.

8. Appointed to be on the International Advisory Board of J Med

Sc, 30 May 2011.

9. Editorial Board Member for WJMG (World Journal of Medical Genetics) (2011-2015). Appointed on 7

th Jan 2011.

10. Editorial Board of Gastroenterology and Hepatology (GH)

(ISSN 1925-9611 [Print]; ISSN 1925-962X [Online]). Appointed on 19 Jul 2011.

11. Associate Editorial Board members for Scholars Academic

Journal of Pharmacy (SAJP) http://saspublisher.com/the-editorial-board-of-sajp/; ISSN 2320-4206 (Appointed Nov 2012).

12. Advisory Editorial Board Members for Scholar Academic

Journal of Biosciences (Appointed Nov 2012).

13. International Board of Reviewers for Informing Science & IT Education (InSITE) Conference 2013, Porto, Portugal.

14. Advisory Editorial Board for Open Access (OA) Alternative

Medicine, OA Publishing, London (indexed by Scopus) (Appointed Feb 2013).

15. Lead guest editor for Special Issue of Evidence-Based

Complementary and Alternative Medicine entitled “Medicinal Plants in Management of Type 2 Diabetes and Neurodegenerative disorders (ND)” Aug 2013.

16. Lead guest editor for Special Issue of Evidence-Based

Complementary and Alternative Medicine entitled“ Enzyme

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Inhibitors from Medicinal Plants in Management of Various Disorders” Aug 2013.

17. Guest editor for Special Issue of Journal of Diabetes Research

entitled “Natural Products and Diabetes” 2016.

18. Editorial Board Member for Evidence-Based Complementary and Alternative Medicine by Hindawi Publishing Corporation, 27 Aug 2013- current.

19. Chief Editor for Scholars Journal of Applied Medical Sciences

(SJAMS) http://saspublisher.com/editorial-board-of-sjams/

20. Chief Editor for Scholars Journal of Medical Case Reports (SJMCR) http://saspjournals.com/sjmcr-editorial-board/

21. Editorial Board for Journal for Universitas Gadjah Mada,

Jogjakarta, Indonesia (Jan 2016-current).

22. Academic Editor for Plos One Journal. Date of appointment: May 2016-current.