gait mechanics influence healthy cartilage morphology and osteoarthritis of the knee by thomas p....

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Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone Joint Surg Am Volume 91(Supplement 1):95-101 February 1, 2009 ©2009 by The Journal of Bone and Joint Surgery, Inc.

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Page 1: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee

by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan

J Bone Joint Surg AmVolume 91(Supplement 1):95-101

February 1, 2009

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 2: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

A typical three-dimensional color thickness map of femoral and tibial cartilage.

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 3: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

The adduction moment at the knee is associated with the medial-to-lateral load distribution at the knee.

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 4: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

The ratio of the medial thickness to lateral thickness in the load-bearing regions of healthy knees (represented by orange circles and dashed linear regression line, R2 = 0.26) during walking is

greater for individuals who walk with a higher adduction momen...

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 5: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 6: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 7: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

The anterior and posterior shifts shown in Figure 3-A move general contact regions to areas of thinner cartilage in the medial compartment.

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 8: Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Thomas P. Andriacchi, Seungbum Koo, and Sean F. Scanlan J Bone

Healthy cartilage homeostasis is maintained by the magnitude of the repetitive cyclic loads during walking, and cartilage is thicker in regions with higher loads during walking.

Thomas P. Andriacchi et al. J Bone Joint Surg Am 2009;91:95-101

©2009 by The Journal of Bone and Joint Surgery, Inc.