Future Research Directions

Improving the Chain of Recovery for Acute Stroke in Your

Community

Overview

Disease understanding

Genetics/Genomics/Proteomics

Primary Prevention

Cerebrovascular disease

Stroke

Secondary Prevention

Acute Stroke Treatment

Recovery and Rehabilitation

Overview

Disease understanding

Genetics/Genomics/Proteomics

Primary Prevention

Cerebrovascular disease

Stroke

Secondary Prevention

Acute Stroke Treatment

Recovery and Rehabilitation

Trial Preparation

Now

More CreativeMethodology

More ThoroughPhase I and Phase IIStudies

Trial Design

Now

Simpler

Larger

Trial Design

Now

Simpler

Larger

$$$$$$

Disease Target

StrokeSAH

StrokeSAH+ICH

Trial Organization

Academic Consortium

Networks of Practicing Physicians

Ischemic Stroke

• Refining Thrombolysis• Drug• Dose• Route

• Clot removal

• Neuroprotection• Combination• Early treatment• Hypothermia

Research Community

• Increasingly, clinical trials will become a part of clinical practice.

Conclusions

• The distinction between research and practice will diminish

Conclusions

• The distinction between research and practice will diminish.

• The importance of rapid response and early intervention will NOT change.

Conclusions

• The distinction between research and practice will diminish.

• The importance of rapid response and early intervention will NOT change.

• Disability and death from stroke will be reduced in gradual decrements in an ongoing process.

Conclusions

• The distinction between research and practice will diminish.

• The importance of rapid response and early intervention will NOT change.

• Disability and death from stroke will be reduced in gradual decrements in an ongoing process.

• There will be a trial testing an intervention for every stroke patient.