Fungal Colonic Mass : Basidiobolus

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Fungal Colon mass : Basidiobolus colitis

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<ul><li><p>FUNGAL MASS : Rt. Iiac </p><p> Fossa </p><p>Case presentation Dept.Histopathology </p><p>KFUCH, KSA </p></li><li><p>Clinical details </p><p>18 YRS FEMALE </p><p>YEMENI </p><p>RT.ILIAC FOSSA MASS </p><p>? LYMPHOMA </p><p>?FUNGAL INFECTION </p></li><li><p>FROZEN STUDY </p><p>1 st SAMPLE : INFLAMMATORY </p><p>2nd SAMPLE : MASS OF BOGGY SOFT TISSUE &amp; FAT </p><p>6cmX4cms </p><p>FROZEN DIAGNOSIS : </p><p>NECROTIZING FUNGAL INFLAMMATION </p></li><li><p>SPLENDORE HOEPPLI MATERIAL </p></li><li><p>DIAGNOSIS </p><p>FUNGAL INFLAMMATORY MASS : </p><p>Zygomycosisspecies Of -? Sub </p><p>** Fungal cultures are recommended for identification of exact type. </p></li><li><p>Fungal infection </p><p>&gt;100,000 fungal species </p><p>Only 150 are pathogenic for humans </p><p> -: FACTORS AFFECTING </p><p>1)Virulence of agent </p><p> 2) Route of infection </p><p> 3)Dose of the agent </p><p>4) Immunological status of host. </p></li><li><p>Broad Categories </p><p>1. Superficial fungus </p><p>2.Cutaneous&amp;sub-cutaneous </p><p>3.Systemic mycoses </p><p>4.Infections that resemble Mycosis </p></li><li><p>Terminology </p><p>Filament that forms the thallus or body of most : HYPHAfungi. </p><p>like filament produced -Short hyphal: PSEUDOHYPHAby the sucessive buds of a yeast that elongate and fail to </p><p>separate. </p><p>: having craoss walls.SEPATE </p><p> : HOEPPLI Material-SPLENDOREEosinophilic substance ,surrounding some fungi, represents a </p><p>localized antigen antibody reaction in hypersensitizesd host. </p></li><li><p>Lab Diagnosis of Fungal infection </p><p> Fungal Culture &amp; Morphology. 1 </p><p>KOH preparation,Microscopy </p><p> :.Immunohistology2 </p><p>DFA(direct fluorescent antibody), </p><p>Immunohistochemical method, </p><p>Molecular tests- DNA/RNA based(PCR). </p><p>.Serological:3 </p><p> Latex agglutination,Complement fixation,ELISA </p><p>.Blood Antigens:4 </p><p> Galactomannan,Glucan </p></li><li><p>Angioinvasive Fungi </p><p>.Zygomycosi(mucormycosis) </p><p>Aspergillus spcs </p><p>Systemic Phycomycetes </p><p>Occasionally Candida albicans </p></li><li><p>SPLENDORE HOEPPLI material </p><p>SC PHYCOMYCOSIS (Basidiobolus sps) </p><p>SUBMUCOUS PHYCOMYCOSIS : (Entomotphthora coronata) </p><p>ASPERGILLUS </p><p>SPOROTHRIX </p></li><li><p>,6, No:39, Vol:2001Reference: Jr.Clinical microbiology, June .GIT Basidiobolus Rt.Iliac fossa massDr Z.U.Khan, Kuwait : </p></li><li><p>Thank </p><p>u </p></li></ul>