DAILY CARE

FOR DRY, SENSITIVEAND IRRITATED SKIN

Help your patientsrestore skin balance

and well-being

Hypoallergenic and non-comedogenic.No fragrances, preservatives, dyes or recognisedirritants

Physiogel®

*DMS: Derma Membrane Structure**Vegetable-based lipids: ceramides, hydrogenated lecithin (phospholipid),squalane, triglyceride, sterol

1. Wohlrab J., Donald A., Albrecht M. Influence of HydrogenatedPhosphatidylcholine (HPC)-Cream vs. Emulsifier-Cream on the structure of the lipidSkin-Lipid Barrier. Abstract.

# Palmitoylethanolamide## This was a multicenter, observational, non-controlled, prospective cohort studyconducted to yield data from physicians and patients with patients 2 to 70 yearsof age with mild-to-moderate atopic eczema on the efficacy, safety, andacceptance of the study cream (Physiogel® A.I. Cream) under daily life conditionsfor 4 to 6 weeks of use.

2. Lambert DM, et al. The palmitoylethanolamide family: a new class of anti-inflammatory agents? Curr Med Chem. 2002 Mar;9(6):663-74.

3. Eberlein B., et al. Adjuvant treatment of atopic eczema: assessment of anemollient containing N-palmitoylethanolamine (ATOPA study). J Eur AcadDermatol Venereol. 2008;22(1):73-82.

Clinically tested

Lipid film** structured in layersto mimic the skin

DMS®*a well-toleratedmoisturizing base

PEA#:naturally occurring ingredient withanti-inflammatory properties (2)

Proven benefits for symptomsof irritated and reactive skin##(3)

� Helps maintain hydration of the skin

� Gentle on the epidermis

QNo penetration into deeper skin layers (1)

Evaluation by doctors on 4-point scaleWhere 0 = absence of symptoms and 3 = severe symptoms.� p < 0.001vs start of study.

2.5

2.0

1.5

1.0

0.5

0Dryness

n = 2269

Start of study

▲

Rednessn = 2263

Itchn = 2265

▲

▲

End of study

Mean Symptom Scores(Physicians' Assessments)

Q Repair of the lipid barrier

Unique formulation Properties:QMoisturizing (2)

QSoothing (2)

In a DMS®base(2)

Physiogel®Physiogel® A.I. Cream

Unique combination of ingredientsto protect and soothe dry, sensitive

and irritated skin

1. Lambert DM, et al. The palmitoylethanolamide family: a new class of anti-inflammatory agents? Curr Med Chem. 2002 Mar;9(6):663-74.

2. Eberlein B, et al. Adjuvant treatment of atopic eczema: assessment of an emollientcontaining N-palmitoylethanolamine (ATOPA study). J Eur Acad DermatolVenereol. 2008;22(1):73-82.

Physiogel® Cream Physiogel® A.I. CreamDaily careto be appliedmorning andevening

Daily careto be appliedmorning andevening

Advantages

QRepairs the lipid barrierwith DMS®

QHelps to rehydrate dry skin

QNo fragrances,preservatives or dyes

Advantages

QAll the advantages ofPhysiogel®Cream

QContains PEA to protectagainst irritation and rednessdue to reactive skin (1,2)

QReduces itch

QIdeal for the entire body

QTo be applied morningand evening

QFormulated forapplication tolarge areas

Also for the body:

Dry and sensitive skin Dry, irritated and reactive skin

Physiogel®

Also for the body: Physiogel® A.I. BalmPhysiogel® Body Lotion

Focus on daily facial and body care

With DMS®, forprotection fromthe moment youtake your shower

Non-rinsedermo-cleanserand make upremover

Non-dryingformula

Apply to wet hair.Work in and thenrinse thoroughly

Minimal foamproduced

Daily use

Advantages

QHypoallergenic

QCombines 3 mild surfactants, gentleon the skin and scalp

QContains a conditioning agentand provitamin B5 for easy untanglingand glossy, soft hair with volume

QNo fragrances, parabens, colorings,or phenoxyethanol

This product does not contain DMS®

QSoap free, contains sodium cocoylisethionate,a cleansing and soothing ingredient

This product contains parabens. This product does not contain DMS®

Physiogel®Extra-gentle cleansing cream Sensitive and itchy scalp

Also for the face: Physiogel® Dermo-Cleanser

Physiogel® Shower-Cream Physiogel® Shampoo-Plus

Focus on daily cleansing care

Helps restore skin balance & well-being

Dry, irritated and reactive skin

Dry and sensitive skin

Very dry, irritated and reactive skin

Very dry and sensitive skin

Latest additionto the range

Redness & Irritation

Physiogel®

QHypoallergenic and non-comedogenic• No fragrances, preservatives, dyes or recognised irritants

QMoisturizing base that is skin-compatible• Hydrogenated lecithin + DMS®

Physiogel® A.I. Cream

Physiogel® Body Lotion

Physiogel® A.I. Lotion

Physiogel® Cream

Physiogel®Shower-Cream

Physiogel®Dermo-Cleanser

Physiogel®Shampoo-Plus

Physiogel® Intensive

Physiogel® A.I. Balm

Sensitivity

Very DryDry

Date of preparation: April 2011 SEU/PSG/0002/11

*

* Contains parabens

Other formulations for daily cleansing care