Fly Pushing The Theory and Practice of Drosophila Genetics By Ralph J. Greenspan, New York University Entertaining and lucid, Greenspan guides the reader carefully through the practicalities of making crosses, isolating variants, mapping genes, constructing specific genotypes, and analyzing mutations. No previous knowledge of fly genetics is as- sumed. The techniques used are il- lustrated, and practice problems and solutions are included to assist the reader. 1997, 155 pp., illus., appendices index Cloth $35 ISBN 0-87969-492-0

Fly.. Push,ng

Oxidative Stress and the Molecular Biology of Antioxidant Defenses Monograph 34 Edited by John G. Scandalios, North Carolina Sta University Written and edited by leaders in this growing fi, this volume is an essential work of reference for specialists and investigators with wider interests cell biology, aging and cancer biology.

1997, 904 pp., illus., color plates, index Cloth $150 ISBN 0-87969-5

Genetic Instability in Cancer Cancer Surveys, V o l u m e 28

Edited by Thomas Lindahl, Imperial Cancer Research Fund This series, edited by J. Tooze (as of Volume 26), provides a comprehen- sive survey of the present state and future developments in well-defined areas in oncology. Each issue deals with a specific topic and has guest editors with an expert knowledge of the subject. 1996, 353 pp., illus., color plates index Cloth $90 ISBN 0-87969-485-8

Epigenetic Mechanisms of Gene Regulation Monograph 32 Edited by Vincenzo E.A. Russo, Max-Planck-lnstitut fiir Molekulare Genetik; Robert A. Martienssen, Cold Spring Harbor Laboratory; Arthur D. Riggs, Beckman Research Institute of the City of Hope This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesise what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

1996, 692 pp., illus., color plates, glossary, index Cloth $125 ISBN 0-87969-490-4

C elegans II Monograph 33 Edited by Donald L. Riddle, Univer- sity o{ Missouri, Columbia; Thomas Blumenthal, Indiana University; Bar- bara J. Meyer, University of Califor- nia, Berkelo 5" and James R. Priess, Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle This volume is a must for any inves- tigator doing worm studies but it has been written and rigorously edited for a wider community of in- vestigators in cell and molecular biology who should know how new knowledge of C. e/egans relates to their own specialty.

1997, 1222 pp., illus., color plates, index Cloth $175 ISBN 0-87969-488-2

Correcting the Blueprint of Life An Historical Account of the Discovery of DNA Repair Mechanisms By Errol C. Friedberg, The University of Texas South- western Medical Center, Dallas In this brief, readable, and revealing book, one of the pioneers of the now rapidly evolving field of DNA repair traces the history of the discovery of the more important mechanisms by which cells respond to DNA damage. Errol Friedberg has writ- ten an enjoyable and informative introduction to the study of DNA mutagenesis and repair that will interest students at an advanced undergraduate or graduate student level as well as investigators in fields as diverse as oncogenesis, cell cycle regula- tion, transcription and DNA replication. Due May 1997, 230 pp. (approx.), illus., index Cloth $49 ISBN 0-87969-507-2

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Copyright �9 1997 by Cold Spring Harbor Laboratory Press

Volume 3 Number 5

January/February 1997 Pages 341-444

Review

How Big is Human Memory, or On Being Just Useful Enough . . . . . . . . . . . . . . . . . . . 341 Yadin Dudai

Research papers

Nonassociative and Associative Modification of Head-Waving Produced by Aversive Tentacular Stimuli in A p l y s i a . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 6 6 Kent K. Fitzgerald, Catherine A. Takacs, and Thomas J. Carew

Multiple Forms of Facilitation Produced by Aversive Tentacular Stimuli in Cerebral Ganglion Sensory Neurons of A p l y s i a . . . . . . . . . . . . . . . . . . . . . . . . . 376 Kent K. Fitzgerald and Thomas J. Carew

An Autonomous Kinase Generated Durin~ Long-Term Facilitation in Aplysia is Related to the Ca'§ Protein Kinase C Api I1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 Wayne S. Sossin

Suppression of c-los Induction in Rat Brain Impairs Retention of a Brightness Discrimination Reaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402 Rita Grimm, Horst Schicknick, Isolde Riede, Eckart D. GundelFmger, Thomas Herdegen, Werner Zuschratter, and Wolfgang Tischmeyer

Modification of Hippocampal Synaptic Proteins by Nitric Oxide-Stimulated ADP Ribosylation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 414 Brian M. Sullivan, Stephen Wong, and Erin M. Schuman

The Drosophila Mutation turnip Has Pieiotropic Behavioral Effects and Does Not Specifically Affect Learning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425 Robert M. Mihalek, Christopher J. Jones, and Tim Tully

Cover Suppression of c-Fos IR expression by c-fos AS-ODN in hippocampal and cortical regions of the rat brain. (Center) Coronal section showing hippocampal and cortical regions. (Insets) Magnifications of dentate granule cell layers shown boxed in the coronal section: c-fos AS-ODN (lower left) and control-ODN (upper right). (For details, see Grimm et al., p. 402.)