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The main reason for the submission of these data is that they are the 3 cohorts used in the following paper: Power, J.D., K.A. Barnes, A.Z. Snyder, B.L. Schlaggar, S.E. Petersen (2011). Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage Epub ahead of print, doi:S1053- 8119(11)01181-5 [pii] 10.1016/j.neuroimage.2011.10.018 All of these subjects are controls with no diagnosis. Full scale IQ scores are from the 2 subtest WASI. Many of the subjects were also used for analyses in the following journal articles: Power, J.D., et al. (2011). Functional network organization in the human brain. Neuron 72, 665-678 Vogel, A.C., Power, J.D., Petersen, S.E., Schlaggar, B.L. (2010). Development of the brain’s functional network architecture. Neuropsychol Review. 20:362–375. Dosenbach, N.U.F., Nardos, B., Cohen, A. L., Fair, D. A., Power, J. D., Church J.A., Nelson, S. M., Wig G.S., Vogel, A.C., Lessov- Schlaggar, C.N., Barnes, K.A., Dubis, J.W., Feczko, E., Coalson, R. S., Pruett Jr.,J.R., Barch, D. M., Petersen, S. E., Schlaggar, B. L. (2010). Prediction of individual brain maturity using fMRI. Science 329, 1358-1361. doi:329/5997/1358 [pii] 10.1126/science.1194144 Power, J.D., Fair, D.A., Schlaggar, B.L., Petersen, S.E. (2010). The development of human functional brain networks. Neuron 67:735-748. Barnes, K. A., Cohen, A. L., Power, J. D., Nelson, S. M., Dosenbach, Y. B. L., Miezin, F. M., Petersen, S. E., and Schlaggar, B. L. (2010). Identifying Basal Ganglia divisions in individuals using resting-state functional connectivity MRI. Front Syst Neurosci 4, 18. Barnes, K.A., et al. (2011). Parcellation in left lateral parietal

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Page 1: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

The main reason for the submission of these data is that they are the 3 cohorts used in the following paper:

Power, J.D., K.A. Barnes, A.Z. Snyder, B.L. Schlaggar, S.E. Petersen (2011). Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage Epub ahead of print, doi:S1053-8119(11)01181-5 [pii] 10.1016/j.neuroimage.2011.10.018

All of these subjects are controls with no diagnosis. Full scale IQ scores are from the 2 subtest WASI.

Many of the subjects were also used for analyses in the following journal articles:

Power, J.D., et al. (2011). Functional network organization in the human brain. Neuron 72, 665-678

Vogel, A.C., Power, J.D., Petersen, S.E., Schlaggar, B.L. (2010). Development of the brain’s functional

network architecture. Neuropsychol Review. 20:362–375.

Dosenbach, N.U.F., Nardos, B., Cohen, A. L., Fair, D. A., Power, J. D., Church J.A., Nelson, S. M., Wig G.S.,

Vogel, A.C., Lessov-Schlaggar, C.N., Barnes, K.A., Dubis, J.W., Feczko, E., Coalson, R. S., Pruett

Jr.,J.R., Barch, D. M., Petersen, S. E., Schlaggar, B. L. (2010). Prediction of individual brain maturity

using fMRI. Science 329, 1358-1361. doi:329/5997/1358 [pii] 10.1126/science.1194144

Power, J.D., Fair, D.A., Schlaggar, B.L., Petersen, S.E. (2010). The development of human functional

brain networks. Neuron 67:735-748.

Barnes, K. A., Cohen, A. L., Power, J. D., Nelson, S. M., Dosenbach, Y. B. L., Miezin, F. M., Petersen, S. E.,

and Schlaggar, B. L. (2010). Identifying Basal Ganglia divisions in individuals using resting-state

functional connectivity MRI. Front Syst Neurosci 4, 18. 

Barnes, K.A., et al. (2011). Parcellation in left lateral parietal cortex is similar in adults and children.

Cereb Cortex CerCor-2011-00246.R1,

Nelson, S.M., Cohen, A., Power, J., Wig, G., Miezin, F.M., Wheeler, M.E., Donaldson, D.I., Velanova, K.,

Phillips, J., Schlaggar, B.L., Petersen, S.E. (2010) A Parcellation Scheme for Human Left Lateral

Parietal Cortex. Neuron, 67(1):156-170.

Nelson, S.M., Dosenbach, N.U., Cohen, A.L., Wheeler, M.E., Schlaggar, B.L., Petersen, S.E. (2010) Role

of the anterior insula in task-level control and focal attention. Brain Structure and Function,

214:669-680.

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Study 0: Functional Connectivity Regions (repeat from initial submission)

Names and Titles of PI and all senior personnel members

Steve Petersen, Ph. D.James S. McDonnell Professor of Cognitive NeuroscienceDirector, McDonnell Center for Systems NeuroscienceDepts. of Neurology and PsychologyWashington University Medical School 

Bradley L Schlaggar MD PhD A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in NeurologyAssociate Professor of Radiology, Pediatrics, and Anatomy & NeurobiologyDirector, Pediatric Neurology Residency Training ProgramDirector, Pediatric Movement Disorder ProgramWashington University School of Medicine & St. Louis Children's Hospital

Alexander L. Cohen Graduate Student

Funding Sources/GrantsNSF/IGERT Program Fellowship (Cognitive, Computational, and Systems Neuroscience Pathway) to Alexander L. Cohen

Washington University Chancellor’s Fellowship and UNC/Merk Graduate Science Research Dissertation Fellowship to Damien Fair

NIH NSADA (Brad Schlaggar)NS32979 (Steve Petersen)NS41255 (Steve Petersen)NS46424 (Steve Petersen)The McDonnell Center for Higher Brain Function (Steve Petersen and Brad Schlaggar)The Burroughs Wellcome Fund (Brad Schlaggar)The Charles A. Dana Foundation (Brad Schlaggar)

AcknowledgementsDamien A. Fair, Nico U. F. Dosenbach, Francis M. Miezin, Donna Dierker, David C. Van Essen, Jessica A. Church, Steven M. Nelson, John Harwell

List of Publications that include the data being released

Cohen AL, Fair DA, Dosenbach NU, Miezin FM, Dierker D, Van Essen DC, Schlaggar BL, Petersen SE (2008) Defining functional areas in individual human brains using resting functional connectivity MRI. Neuroimage 41:45-57

Page 3: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

Resting State Info Eyes open, 5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study Flickering checkerboard quadrants with button press Follow the target saccades Abstract/Concrete judgement on visual words

Page 4: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

Study 1: Augmentative Communication

Names and Titles of PI and all senior personnel members

Steve Petersen, Ph. D.James S. McDonnell Professor of Cognitive NeuroscienceDirector, McDonnell Center for Systems NeuroscienceDepts. of Neurology and PsychologyWashington University Medical School 

Bradley L Schlaggar MD PhD A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in NeurologyAssociate Professor of Radiology, Pediatrics, and Anatomy & NeurobiologyDirector, Pediatric Neurology Residency Training ProgramDirector, Pediatric Movement Disorder ProgramWashington University School of Medicine & St. Louis Children's Hospital

Rebecca S. Coalson B.S. Research Patient Coordinator

Funding Sources/GrantsThe Brooks Family Fund

AcknowledgementsKelly R. McVey, Rebecca L. Lepore, Fran M. Miezin, Mary Downey-Jones, Jane K. Quarles, Tara V. Spevack, Melanie Wood, Janice Lanto, Alex L. Cohen

List of Publications that include the data being releasedNone specifically on this study

Resting State Info Eyes open, 3 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study 5 minute runs watching the movie Finding Nemo or an aquarium video clip

Page 5: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

Study 2: Development of Orthography

Names and Titles of PI and all senior personnel members

Steve Petersen, Ph. D. James S. McDonnell Professor of Cognitive NeuroscienceDirector, McDonnell Center for Systems NeuroscienceDepts. of Neurology and PsychologyWashington University Medical School

Bradley L Schlaggar MD PhD A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology

Associate Professor of Radiology, Pediatrics, and Anatomy & NeurobiologyDirector, Pediatric Neurology Residency Training ProgramDirector, Pediatric Movement Disorder ProgramWashington University School of Medicine & St. Louis Children's Hospital

Alecia C. Vogel, PhD Postdoctoral Fellow

Funding Sources/GrantsR01-Schlaggar-R01HD057076RO1 NS046424

AcknowledgementsRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Gordon Shulman

List of Publications that include the data being released

Vogel AC, Miezin FM, Petersen SE, Schlaggar BL (2011) The putative visual word form area is functionally connected to the dorsal attention network. Cereb Cortex Jun 20. [Epub ahead of print].

Resting State Info Eyes open, 5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study collected 5 minute resting runs at the end of a 2+ hour session of VISUAL

MATCHING AND READING tasks

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Study 3: Jess Task Switching

Names and Titles of PI and all senior personnel members

Bradley L Schlaggar MD PhD A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology

Associate Professor of Radiology, Pediatrics, and Anatomy & NeurobiologyDirector, Pediatric Neurology Residency Training ProgramDirector, Pediatric Movement Disorder ProgramWashington University School of Medicine & St. Louis Children's Hospital

Jessica A. Church, PhD Postdoctoral Fellow

Funding Sources/GrantsNIH NINDS NRSA-F32 NS656492 ChurchNIH NIMH R21-SchlaggarR01-Schlaggar-R01HD057076Tourette Syndrome Association-SchlaggarTourette Syndrome Association-Church

AcknowledgementsRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley), Yannic Dosenbach, Sarah Katie Zeller Ihnen, Kelly Anne Barnes

List of Publications that include the data being released

Church JA, Fair DA, Dosenbach NU, Cohen AL, Miezin FM, Petersen SE, Schlaggar BL (2009) Control networks in paediatric Tourette syndrome show immature and anomalous patterns of functional connectivity. Brain 132:225-238.

Church JA, Wenger KK, Dosenbach NU, Miezin FM, Petersen SE, Schlaggar BL (2009) Task control signals in pediatric Tourette syndrome show evidence of immature and anomalous functional activity. Frontiers in Human Neuroscience 3:38.

Resting State Info Eyes open, 5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study collected 5 minute rest runs interspersed with a task-switching paradigm, eg.

o if the cue is color, press left button for pink or right for greeno if the cue is cartoon, press left for fish or right for squid

Page 7: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

Study 4: Unilateral Hearing Loss

Names and Titles of PI and all senior personnel members

Judith E. C. Lieu, MD, Assistant Professor of Otolaryngology

Bradley L Schlaggar MD PhD A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in NeurologyAssociate Professor of Radiology, Pediatrics, and Anatomy & NeurobiologyDirector, Pediatric Neurology Residency Training ProgramDirector, Pediatric Movement Disorder ProgramWashington University School of Medicine & St. Louis Children's Hospital

Jill B. Firszt, PhD, Associate Professor of Otolaryngology

Banan Ead, Research Patient Coordinator

Funding Sources/GrantsAmerican Hearing Research FoundationNIH grant K23DC006638

AcknowledgementsKathleen Tibbits, Amy Streufert, Rebecca S. Coalson, Fran Miezen

List of Publications that include the data being released

Tibbetts K, Umansky AM, Ead B, Coalson RS, Schlaggar BL, Firszt JB, Lieu JEC. Inter-regional brain interactions in children with unilateral hearing loss. Otolaryngology-Head and Neck Surgery 144 (4):602-611, 2011. doi:10.1177/0194599810394954

Resting State Info Eyes open, 3 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study DTI was also collected

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Study 5: Deanna Barch

Names and Titles of PI and all senior personnel members

Deanna Barch, Gregory B Couch Professor of PsychiatryDirector, Conte Center for the Neuroscience of Mental IllnessWashington University

Lizzie Gilman Professor and Chair, Department of Psychiatry and Behavioral SciencesWashington University

Grega Repovs, Associate Professor, Psychology DepartmentWashington University

Funding Sources/GrantsNIMH grant P50 MH071616

Acknowledgements

List of Publications that include the data being released

Repovs, G., Csernansky, J. G., & Barch, D. M. (2011). Brain network connectivity in individuals with schizophrenia and their siblings. Biological Psychiatry, 69, 967-973.

Repovs, G. and Barch, D. M. (submitted). Working memory related brain network connectivity in individuals with schizophrenia and their sibilngs.

Resting State Info Eyes open, 5.5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study Mixed State Item Nback with loads of 0, 1 and 2 back

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Study 6: Autism Controls

Names and Titles of PI and all senior personnel members

Steve Petersen, Ph. D.James S. McDonnell Professor of Cognitive NeuroscienceDirector, McDonnell Center for Systems NeuroscienceDepts. of Neurology and PsychologyWashington University Medical School 

John R. Pruett, Jr., M.D., Ph.D.Assistant ProfessorDepartment of Psychiatry, Division of Child & Adolescent PsychiatryWashington University School of Medicine

Eric Feczko Graduate Student

Funding Sources/Grants

Simons Foundation Autism Research Initiative – Steve Petersen

Acknowledgements

Sarah Hoertel, Kelly McVey, Fran Miezen, Emma Squire, Anna Abacchi, Angie LaMacchia Moll

List of Publications that include the data being releasedNone specifically on this data yet

Resting State Info Eyes open, 5 minute runs White fixation cross on black background “Do you see the plus sign?” “For the next scan, keep your eyes open, try not to move your head, arms, legs,

hands, feet, fingers, or toes, but you can blink and breathe like you normally would. Try your best to look at the plus sign and this scan will take about five and a half minutes. Let me know as soon as you’re ready to start”

Other Tasks in this Study Fixate on plus sign, periodically a flickering checkerboard will appear

o Press one button when it appears; Press another button when it disappears Eyes closed rest DTI was collected

Page 10: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

Study 7: Tammy Hershey

Names and Titles of PI and all senior personnel membersTamara Hershey, Ph.D.Associate ProfessorPsychiatry, Neurology and Radiology DepartmentsWashington University School of Medicine

Funding Sources/GrantsDiabetes Research and Training Center at Washington University and the National Institute of Diabetes and Digestive and Kidney Diseases (5 P60 DK020579-31)

AcknowledgementsHeather Lugar, Brenda Kirchhoff

List of Publications that include the data being releasedNone specifically on this study

Resting State Info Eyes open, 5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study an associative encoding task

Page 11: fcon_1000.projects.nitrc.orgfcon_1000.projects.nitrc.org/indi/retro/Power2012/...  · Web viewRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),

Study 8: Scanner Comparison

Names and Titles of PI and all senior personnel members

Carolyn Pizoli, MD/PhDAssistant ProfessorDivision of Pediatric NeurologyDuke University Medical Center

Christine Mac Donald, PhDResearch Instructor, Department of NeurologyDirector - Advanced MRI and Blast-Related TBI StudyWashington University School of Medicine

David Brody, MD, PhDAssistant Professor in the Department of NeurologyWashington University site director for the National Football League player care program

Funding Sources/GrantsK 12 NS-001690  is the NSADA K12

AcknowledgementsTammy Benzinger

List of Publications that include the data being released None specifically on this data

Resting State Info Eyes open, 5 minute runs No other instructions, no fixation cross

Other Tasks in this Study DTI also acquired

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Study 9: Twin Study

Names and Titles of PI and all senior personnel members

Christina N. Lessov-Schlaggar, PhDResearch Assistant Professor of PsychiatryWashington University School of MedicineDepartment of Psychiatry

Funding Sources/Grants

The study was supported by the Barnes-Jewish Hospital Foundation in Saint Louis, Missouri, and by grants from the McDonnell Center for Systems Neuroscience at Washington University (CNLS), the Alvin J. Siteman Cancer Center (supported in part by an NCI Cancer Center Support Grant #P30 CA91842) at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, Missouri, for use of the Prevention and Control Research Program (CNLS), and NIH grant DA027046 (CNLS). Diagnostic interview surveys of the total twin cohort were supported by NIH grant AA009022 (ACH).

AcknowledgementsRebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen

List of Publications that include the data being released

Lessov-Schlaggar CN, Lepore RL, Kristjansson SD, Schlaggar BL, Barnes KA, Petersen SE, Madden PAF, Heath AC, Barch DM. Functional neuroimaging study in identical twin pairs discordant for regular cigarette smoking. Addiction Biology (accepted)

Resting State Info Eyes open, 5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study Monetary reward task – guess whether hidden number is larger or smaller than 5. If

correct, win $1; if wrong, lose 50 cents. Smoking status of individuals was assessed, as well as blood CO levels. Identical twins were recruited for this study.

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Study 10: Joe’s First Visual Attention

Names and Titles of PI and all senior personnel members

Steve Petersen, Ph. D.James S. McDonnell Professor of Cognitive NeuroscienceDirector, McDonnell Center for Systems NeuroscienceDepts. of Neurology and PsychologyWashington University Medical School 

Bradley L Schlaggar MD PhD A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in NeurologyAssociate Professor of Radiology, Pediatrics, and Anatomy & NeurobiologyDirector, Pediatric Neurology Residency Training ProgramDirector, Pediatric Movement Disorder ProgramWashington University School of Medicine & St. Louis Children's Hospital

Joseph W Dubis Graduate Student

Funding Sources/Grants

McDonnell Foundation GrantR21

AcknowledgementsRebecca S Coalson, Kelly McVey, Rebecca Lepore, Joshua Siegel, Mary Downey-Jones, Fran Miezen

List of Publications that include the data being released None specifically on this data yet

Resting State Info Eyes open, 5 minute runs White fixation cross on black background "loosely fixate on the white cross"

Other Tasks in this Study After a spatial left or right cue arrow, shapes appeared. Subjects pressed a button

when they detected that one of the shapes changed orientation angle.