FASCIOLA HEPATICA

FASCIOLA hepatica

Disease:Fascioliasis & liver rot in animals.

Distribution:- Common in cattle & sheep raising

countries.

FASCIOLA hepatica

Definitive host : man

Reservoir host: Cattle, sheep ,goats, buffaloes

Habitat: Bile ducts.

Intermediate host: Lymnaea snails.

Infective stage : Encysted metacercaria.

Mode of infection

Ingestion of raw vegitation or water containing encysted metacercaria.

Life cycle:

Adult FASCIOLA Hepatica

Egg:

•Size : 140 X 70 µm.

•Shape: Oval, Thin walled with

operculum.

• Color : Yellowish brown (bile

stained).

•Contents : Ovum & yolk cells

(immature).

Miracidium

•Pyriform.

•Ciliated.

Lymnaea snails

Cercaria (Leptocercus)Last larval stage inside the

snail.

No sexual organs.

Cystogenous glands (help in passing out of snail & in encysting on vegetations or water).

Tail: simple & helps in leaving the snail.

Encysted MetacercariaWithout tail.

Surrounded by a

cyst

wall.

Clinical Picture :Fever.

Pain & tenderness in right hypochondrium.

Biliary colics.

Hepatomegaly,

Jaundice.

Vomiting & diarrhoea.

Toxaemia.

Anaemia & eosinophilia.

Diagnosis

I. Clinically : A highly suggestive tetrad of:

Fever.

Hepatomegaly.

Pain & tenderness in the right hypochondrium.

Eosinophilia.

Diagnosis

II- Laboratory : a. Direct methods

1. Stool examination by direct smear & concentration methods to find the characteristic eggs.

2. Bile aspiration from the duodenum & examine for eggs.

3. US.

4. Computerized tomography (C.T).

Diagnosis

Diagnosis

b. Indirect Methods

ELISA, IHA ,CIEP

Eosinophilia.

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