NURS 2516 Clinical Medications WorksheetsGeneric NameFamotidine

Trade NamePepcid

ClassificationHistamine H2 Antagonists

Dose20mgDosage range:20 mg up to twice a day

RoutePO

Time/frequencyEvery 12 Hours PRN

Peak0.5-3 hr

Onsetwithin 60 min

Duration8-15 hr

For IV meds, compatibility with IV drips and /or solutionsn/a

Mechanism of action and indications(Why med ordered)Inhibits the action of histamine at the H2-receptor sites in gastric parietal cells, resulting in inhibition of gastric acid secretion. Indicated to Management of urticaria, Management of GI symptoms associated with the use of NSAIDs,

My patient is getting this medication for symptoms of gerd

Nursing Implications (what to focus on) Contraindications/warnings/interactionsHypersensitivity. Products containing alcohol should be avoided in pt’s w/ known intolerance. Renal impairment (more susceptible to adverse CNS reactions; increased dosage interval recommended if CCr <10 ml/min

Common side effectsCNS: c\Confusion, dizziness, drowsiness, hallucinations, headacheCV: Arrhythmias GI: Altered taste, constipation, diarrhea, nauseaHemat: Agranulocytosis, Aplastic anemia, anemia, neutropenia, thrombocytopenia

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically)none

Lab value alterations caused by medicineAntagonize the effects of pentagastrin and histamine during gastric acid secretion testing. May cause false-negative results in skin tests using allergenic extracts. Should be avoided for 24 hours before either tests. May cause an increase in serum transaminases and serum creatinine.

Be sure to teach the patient the following about this medicationMay cause drowsiness or dizziness, be cautious while participating in activities that require alertness until the response to the drug is known. Advise pt to avoid foods that may cause an increase in GI irritation. Inform pt that increase in fiber, fluid, and exercise may minimize constipation. Advise pt to report onset of black tarry stools, fever, sore throat, diarrhea, dizziness, rash, confusion, or hallucinations to health care professional promptly.

Nursing Process- Assessment(Pre-administration assessment)Assess CNS for confusion dizziness, drowsiness, hallucinations, and headache

AssessmentWhy would you hold or not give this med?If pt is experiencing CNS side effects especially confusion, epigastric or abdominal pain, or has frank or occult blood in stool emesis or gastric aspirate, report promptly

EvaluationCheck after givingDecrease in abdominal pain, heartburn, acid indigestion, and sour stomach