familial hypercholesterolaemia - my family history by john moore as told to devi nair

Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

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Familial Hypercholesterolaemia

- My Family History

By John Moore

as told to Devi Nair

Family History - JM

JMJM

TC 12.0(mmol/L)

Index CaseIndex Case

1929

Page 3: Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

Family History - JM

JMJM

TC 12.0(mmol/L)

Index CaseIndex Case

1929

First degree relatives 1 in 2 chanceSecond degree relatives 1 in 4 chance

Page 4: Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

Family History - parents

IIII

JMJM

TC 12.0(mmol/L)

Index CaseIndex Case

FF MM

1929

First degree relatives 1 in 2 chanceSecond degree relatives 1 in 4 chance

†57y †42y

Page 5: Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

Family History - siblings

IIII

JMJM

TC 12.0(mmol/L)MI age

Index CaseIndex Case

ffmm

55 y

First degree relatives 1 in 2 chanceSecond degree relatives 1 in 4 chance

†57y †42yMI age 50

MI age 50

High cholesterol

pat

Old age

MI age 50angina

Page 6: Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

Family History - children

IIII

JMJM

TC 12.0(mmol/L)MI age

Index CaseIndex Case

55 y

†57y †42y

MI age 50

High cholesterol

pat

Old age

anna

MI age 50angina

IIIIII1959 4.3/2.4

1954 On RX

1953 on RX

1951On Rx

Page 7: Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

Family History – grand children

IIII

JMJM

TC 12.0(mmol/L)MI age

Index CaseIndex Case

ffmm

55 y

†57y †42yMI age 50

MI age 50

High cholesterol

pat

Old age

anna

MI age 50angina

?tested

iviv

1992 1990TC 6 LDL 3.8 6.3 /4.3

1987 1985 1983 2,6/0.43 3.1/1.5 5.1/2.9

1989 3.8/2. NT NT

Page 8: Familial Hypercholesterolaemia - My Family History By John Moore as told to Devi Nair

Family History – grand children

IIII

JMJM

TC 12.0(mmol/L)MI age

Index CaseIndex Case

ffmm

55 y

†57y †42yMI age 50

MI age 50

High cholesterol

pat

Old age

anna

MI age 50angina

?tested

iviv

1992 1990TC 6 LDL 3.8 6.3 /4.3

1987 1985 1983 2,6/0.43 3.1/1.5 5.1/2.9

1989 3.8/2. NT NT

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