ewma 2013-ep432-enzyme alginogels – hydrated alginates with an embedded anti-bacterial enzyme...
DESCRIPTION
¨Palombo M, La Greca C, delli Santi G, Palombo P Burn Center and Plastic Surgery Department- S. Eugenio Hospital - Rome Chief: Prof. P. PalomboTRANSCRIPT
Enzyme alginogels – hydrated alginates with an embedded anti-bacterial enzyme system in the Treatment of Pediatric Burn Patient:
Our Experience
Palombo M, La Greca C, delli Santi G, Palombo P
Burn Center and Plastic Surgery Department- S. Eugenio Hospital - Rome Chief: Prof. P. Palombo
[email protected] - +390651002200 Roma Burn Center
Introduction
The goal, in the treatment of deep second-degree burn, is to achieve, in the shortest time, the debridement of the wound to prepare the patients for skin grafting, in the treatment of the superficial second-degree burn, is to reach, avoiding infections and preventing scarring, the restitutio ad integrum.
[email protected] - +390651002200 Roma Burn Center
Aim
This study evaluates the clinical efficacy of enzyme alginogels – hydrated alginates with an embedded anti-bacterial enzyme system (Flaminal® Hydro and Forte) in the second degree burns in pediatric population
[email protected] - +390651002200 Roma Burn Center
Methods
The products were used as wound dressing in pediatric patients with second degree burns between November 2012 and April 2013
Patients
39
Male Female
19 20
The dressing was applied and kept in situ covered by paraffin gauze.
- Ease of application - Pain - Home management - Times of healing - Cosmetic results
[email protected] - +390651002200 Roma Burn Center
Age (range) Age (average)
45 days – 15 years 5 years
We evaluated*
*at each control on a scale from 1 to 10
Results
The medical treatment promoted a faster and complete wound healing without major complications No one children had to stop treatment
In deep II burns the treatment is useful to debride the wound, shortening surgical times
[email protected] - +390651002200 Roma Burn Center
Parameters Scale (average of score)
Ease of application 8.7
Pain* 3.1
Home management (difficulty) 2.2
Times of healing (rate) 8.9
Cosmetic results 9
*measured as duration of crying in infants and young children (20 minutes on average) and reported as mild discomfort in older children (for 20 minutes on average)
Case n.1
Burn by firecracker in child 4 y.o. treated as outpatient with Flaminal ® Forte and Hydro
At the first access
At the first control after six days Controls at 1 month (left photo)
and 3 months (right photo)
[email protected] - +390651002200 Roma Burn Center
Case n.2
[email protected] - +390651002200 Roma Burn Center
Scald of forearm in child 2 y.o. treated as outpatient with Flaminal ® Forte and Hydro
At first access
After six days Outcome
Case n.3
[email protected] - +390651002200 Roma Burn Center
Scald of abdomen in child 6 y.o. treated as outpatient with Flaminal ® Hydro
At first access
After four days
Conclusion
Short terms topical application of the enzyme alginogels – hydrated alginates in pediatric population with second degree burns promoted faster and complete wound healing avoiding infections thanks to its formulation. In deep second degree burn allows the chemical debridement is preparatory to of skin graft
[email protected] - +390651002200 Roma Burn Center
Thanks