EVIDENCE-BASED EVIDENCE-BASED VETERINARY MEDICINEVETERINARY MEDICINE

LITERATURE SEARCHLITERATURE SEARCH

Roos GoverdeRoos GoverdeMarijke NiessenMarijke Niessen

Januari 2010Januari 2010

EBM-tools voor humane EBM-tools voor humane geneeskunde:geneeskunde:

Cochrane LibraryCochrane Library- Systematic Reviews- Systematic Reviews- Register van Clinical trials- Register van Clinical trials

PubMedPubMed- Clinical queries (randomized - Clinical queries (randomized

controlled trials, clinical trials, controlled trials, clinical trials, systematic reviews, ..)systematic reviews, ..)

Vertaal het klinische probleem naar een beantwoordbare vraag (PICO-vraag)

Maak voor ieder onderdeel van de PICO-vraag een lijst van (Engelstalige / wetenschappelijke) synoniemen die je gaat gebruiken als zoektermen in de literatuurbestanden

Selecteer de literatuurbestanden waarin je gaat zoeken

Zoek op ieder onderdeel apart, zodat je later de zoekactie makkelijk kunt aanpassen

Zoeken in stappen op weg naar Zoeken in stappen op weg naar EBVMEBVM

En dan nu EBVMEn dan nu EBVM

Zoek op ieder onderdeel apart, zodat je later de Zoek op ieder onderdeel apart, zodat je later de zoekactie makkelijk kunt aanpassenzoekactie makkelijk kunt aanpassen

Combineer de zoekacties met AND, OR, NOTCombineer de zoekacties met AND, OR, NOT

Stel het type vraag vast: diagnostisch, therapeutisch, Stel het type vraag vast: diagnostisch, therapeutisch, prognostisch, etiologisch, etc.prognostisch, etiologisch, etc.

Gebruik eventueel EBM zoekfiltersGebruik eventueel EBM zoekfilters

Stel het resultaat bij door breder of specifieker Stel het resultaat bij door breder of specifieker te zoeken, of je zoekacties te beperken op taal, te zoeken, of je zoekacties te beperken op taal, publikatiejaar, etc.publikatiejaar, etc.

VoorbeeldVoorbeeldPATIENTPATIENT INTERVENTIEINTERVENTIE COMPARISONCOMPARISON OUTCOMEOUTCOME

BabesiaBabesia

BabesiosisBabesiosis

DogDog

DogsDogs

caninecanine

Diminazene*Diminazene*

““Diminazene Diminazene aceturate”aceturate”

TherapyTherapy

““therapeutic therapeutic use”use” treatment treatment

clinical trial*clinical trial*

random*random*

Imidocarb*Imidocarb*

““Imidocarb Imidocarb Dipropionate”Dipropionate”

Compar*Compar*

(publ.type:)(publ.type:)

““comparative comparative study” study”

LiverLiver

““Liver failure”Liver failure”

““Liver diseases”Liver diseases”

KidneyKidney

““kidney failure”kidney failure”

““kidney diseases”kidney diseases”

““side effects”side effects”

““adverse effects”adverse effects”

““long term long term effects”effects”

PATIENTPATIENT INTERVENTIEINTERVENTIE COMPARISONCOMPARISON OUTCOMEOUTCOME

MastitisMastitis

““Mammary Mammary gland gland diseases”diseases”

CowCow

CowsCows

BosBos

BovidaeBovidae

cattlecattle

Penicillin*Penicillin*

penicillinenpenicillinen

PenicillinsPenicillins

AntibioticsAntibiotics

TherapyTherapy

““therapeutic therapeutic use”use” treatmenttreatment

clinical trial*clinical trial*

random*random*

““Multiple drug Multiple drug therapy”therapy”

““combination combination therapy”therapy”

synergysynergy

Compar*Compar*

(publ.type:)(publ.type:)

““comparative comparative study” study”

““milk yield”milk yield”

““milk milk production”production”

““recuperation recuperation time”time”

VoorbeeldVoorbeeld

LiteratuurbestandenLiteratuurbestanden

Diergeneeskundige literatuur vind je bij diverse Diergeneeskundige literatuur vind je bij diverse disciplines, daarom zijn ook meerdere bestanden disciplines, daarom zijn ook meerdere bestanden belangrijk voor de beantwoording van je vraag: belangrijk voor de beantwoording van je vraag:

diergeneeskunde (CAB-Abstracts en IVIS)diergeneeskunde (CAB-Abstracts en IVIS) geneeskunde / diergeneeskunde (PubMed)geneeskunde / diergeneeskunde (PubMed) landbouwkunde (Agricola)landbouwkunde (Agricola) Diergedrag (Animal behavior abstracts)Diergedrag (Animal behavior abstracts) wetenschap algemeen (Scopus)wetenschap algemeen (Scopus)

NBNB: Zoektools verschillen van bestand tot : Zoektools verschillen van bestand tot bestandbestand

Onderwerpen in CAB-AbstractsOnderwerpen in CAB-Abstracts

applied economics and sociologyapplied economics and sociologyPolicy formation, development programmes, the economics of the foodPolicy formation, development programmes, the economics of the foodindustry, natural resources utilization, farm management, aspects ofindustry, natural resources utilization, farm management, aspects ofeducation and research, and rural sociology.education and research, and rural sociology.

animal productionanimal productionBreeding and genetics of animals of economic importance, animalBreeding and genetics of animals of economic importance, animalproduction, animal nutrition, animal biotechnology, aquaculture, dairyproduction, animal nutrition, animal biotechnology, aquaculture, dairyscience and technology.science and technology.

animal health and behaviouranimal health and behaviour

animal nutritionanimal nutritionAll aspects of nutrition, feeding and metabolism of farm animals,All aspects of nutrition, feeding and metabolism of farm animals,companion animals, equine, zoo and game animals.companion animals, equine, zoo and game animals.

BreedingBreeding

chemistrychemistryPesticides, adjuvants, botanical pesticides, biochemistry of pestPesticides, adjuvants, botanical pesticides, biochemistry of pestorganisms, biocontrol, farmed animals and plants, biofuels, theorganisms, biocontrol, farmed animals and plants, biofuels, thechemistry of soils, fertilizers, freshwater, waste water and nutritionalchemistry of soils, fertilizers, freshwater, waste water and nutritionalbiochemistry.biochemistry.

entomologyentomologyTaxonomy, genetics, behaviour, morphology, physiology, control ofTaxonomy, genetics, behaviour, morphology, physiology, control ofinsects and other arthropods of medical, veterinary or agriculturalinsects and other arthropods of medical, veterinary or agriculturalimportance.importance.

environmental scienceenvironmental science

food science and technologyfood science and technologyEntire food chain – from farm to fork and beyond. Composition, Entire food chain – from farm to fork and beyond. Composition, Quality control, processing, analytical methodologies, safety, Quality control, processing, analytical methodologies, safety, hygiene, effect on human health, technology, and legislation.hygiene, effect on human health, technology, and legislation.

GeneticsGeneticsinvasive speciesinvasive species

natural resources, land/water managementnatural resources, land/water managementAll aspects of soil science and management, land and water resources and All aspects of soil science and management, land and water resources and their managementtheir management

Zoekactie CAB-AbstractsZoekactie CAB-AbstractsSearchesSearches ResultsResults TypeType DisplayDisplay

□□ 11 Exp babesia/ or babesiosis/Exp babesia/ or babesiosis/ 81198119 advancedadvanced displaydisplay

□□ 22 Exp dogs/Exp dogs/ 138659138659 advancedadvanced displaydisplay

□□ 33 1 and 21 and 2 13271327 advancedadvanced displaydisplay

□□ 44 "imidocarb dipropionate"."imidocarb dipropionate".mp. or imidocarb.sh. mp. or imidocarb.sh.

336336 advancedadvanced displaydisplay

□□ 55 "diminazene aceturate".mp."diminazene aceturate".mp.or diminazene.sh. or diminazene.sh.

12451245 advancedadvanced displaydisplay

□□ 66 4 or 54 or 5 15311531 advancedadvanced displaydisplay

□□ 77 4 and 54 and 5 5050 advancedadvanced displaydisplay

□□ 88 (random* or "clinical trials").sh. (random* or "clinical trials").sh. or "systematic reviews".id. or "systematic reviews".id.

1882618826 AdvancedAdvanced displaydisplay

□□ 99 3 and 7 and 83 and 7 and 8 00 advancedadvanced displaydisplay

Zoekactie PubMedZoekactie PubMed#20 Search (#16) AND ((clinical[Title/Abstract] AND trial[Title/Abstract]) 19#20 Search (#16) AND ((clinical[Title/Abstract] AND trial[Title/Abstract]) 19 OR clinical trials[MeSH Terms] OR clinical trial[Publication Type] OR clinical trials[MeSH Terms] OR clinical trial[Publication Type] OR random*[Title/Abstract] OR random allocation[MeSH Terms] OR random*[Title/Abstract] OR random allocation[MeSH Terms] OR therapeutic use[MeSH Subheading]) OR therapeutic use[MeSH Subheading]) #19 Search (#16) AND (randomized controlled trial[Publication Type] 0#19 Search (#16) AND (randomized controlled trial[Publication Type] 0 OR (randomized[Title/Abstract] AND controlled[Title/Abstract] OR (randomized[Title/Abstract] AND controlled[Title/Abstract] AND trial[Title/Abstract])) AND trial[Title/Abstract])) #16 Search (#6) AND (#9) AND (#15) 20#16 Search (#6) AND (#9) AND (#15) 20#15 Search (#12) OR (#14) #15 Search (#12) OR (#14) 580 580#14 Search ("Diminazene"[Mesh] OR "diminazene aceturate "[Substance 463#14 Search ("Diminazene"[Mesh] OR "diminazene aceturate "[Substance 463 Name]) Name]) #12 Search ("Imidocarb"[Mesh] OR "imidocarb dipropionate 131#12 Search ("Imidocarb"[Mesh] OR "imidocarb dipropionate 131 "[Substance Name]) "[Substance Name]) #8 Search (#4) AND (#7)#8 Search (#4) AND (#7) 318 318#7 Search “Dogs”[Mesh]#7 Search “Dogs”[Mesh]

256210256210#4 Search “Babesia”[Mesh] OR “babesiosis”[Mesh]#4 Search “Babesia”[Mesh] OR “babesiosis”[Mesh]

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