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目次明治国際医療大学附属東洋医学研究所の組織・・・・・・・・・・目次裏研究活動の重要な課題・・・・・・・・・・・・・・・・・・・・ 1 明治国際医療大学附属東洋医学研究所の共同利用研究室紹介・・・ 3 研究報告ＭＲセンター研究室・・・・・・・・・・・・・・・・・・・・ 21 臨床研究棟研究室・・・・・・・・・・・・・・・・・・・・・ 23 附属鍼灸センター研究室・・・・・・・・・・・・・・・・・・ 24 微細構造解析室／生体構造解析室／生体機能解析室Ⅱ・・・・・ 25 遺伝子関連物質解析室・・・・・・・・・・・・・・・・・・・ 27 生体防御機構解析室／生体分子解析室・・・・・・・・・・・・ 29

生理活性物質分析室・・・・・・・・・・・・・・・・・・・・ 31 高次機能解析室・・・・・・・・・・・・・・・・・・・・・・ 33 生体機能解析室Ⅰ・・・・・・・・・・・・・・・・・・・・・ 35 生体機能解析室Ⅲ・・・・・・・・・・・・・・・・・・・・・ 37 生体反応解析室Ⅱ／生体機能解析室Ⅱ・・・・・・・・・・・・ 38 薬効解析室・・・・・・・・・・・・・・・・・・・・・・・・ 40 工作室・・・・・・・・・・・・・・・・・・・・・・・・・・ 41 2 号館分子シグナル解析室・・・・・・・・・・・・・・・・・ 42 6 号館診断情報解析室・・・・・・・・・・・・・・・・・・・ 44 8 号館運動機能解析室・・・・・・・・・・・・・・・・・・・ 46 10 号館看護情報解析室・・・・・・・・・・・・・・・・・・ 48 明治国際医療大学附属東洋医学研究所の研究業績一覧・・・・・・ 51

明治国際医療大学附属東洋医学研究所年報　2014

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S, Masumoto T, Fujisawa M, Kato M, Chikaishi T, Kawasaki Y, Kinoshita S, Itoi M, Sakaguchi N, Miyazawa M.Infection of adult thymus with murine retrovirus induces virus-specific central tolerance that prevents functional memory CD8+ T cell differentiation.: Pros Pathogens. 2014. 10(3): e1003937.

2) Miyazaki M, Miyazaki K, Chen S, Itoi M, Miller M, Lu L-F, Varki N, Chang AN, Broide DH, Murre C.: Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease. Nat Immunol. 2014. 15(8): 767-776.

1) Itoi M and Chiba S.: The contribution of Lymphotoxin Beta Receptor signal to the Development of cortical Thymic epithelial Cells. ThymOz : An International Workshop on Thymus Biology and T Lymphocytes. April 2nd-7th, Heron Island, Australia. 7:21. 2014.

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Iwasaki T, Mizui T, Takahashi H, Hanamura K,

Roppongi RT, Koibuchi N, Sekino Y, Mori N, Shirao T. Spikar, a novel drebrin-binding protein, regulates the formation and stabilization of dendritic spines. J.Neurochem.,128(4):507-522,2014.

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1) Bito Y, Hirata K, Ebisu T, Kawai Y,

Otake Y, Hirata S, Shirai, T, Soutome Y, Ochi H, Yamamoto E, Umeda M, Higuchi T, Tanaka C : Diffusion-weighted Line-scan Echo-planar Spectroscopic Imaging Technique to Reduce Motion Artifactgs in Metabolite Diffusion Imaging. Magn Reson Med Sci.14(1) 43-50, 2014.

2) Yamamoto H, Yamamoto H,Mano H, Umeda M, Higuchi T, Saiki J, Activity in early visual areas predicts interindividual differences in binocular rivalry dynamics. J Neurophysiol 111: 1190 1202, 2014

3) Inoue M, Nakajima M, Oi Y, Hojo T, Itoi M, Kitakoji H: The effect of electroacupuncture on tendon repair in a rat Achilles tendon rupture model.

4) Inoue M, Nakajima M, Hojo T, Itoi M:


Relaxing effect of acupuncture stimulation on hypertonic muscle in rats. J Jpn Soc Balneol Climatol Phys Med. 2014. (in press)

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10)Takamura S, Kajiwara E, Tsuji-Kawahara S, Masumoto T, Fujisawa M, Kato M, Chikaishi T, Kawasaki Y, Kinoshita S, Itoi M, Sakaguchi N, Miyazawa M.Infection of adult thymus with murine retrovirus induces virus-specific central tolerance that prevents functional memory CD8+ T cell differentiation.: Pros Pathogens. 2014. 10(3): e1003937.

11)Miyazaki M, Miyazaki K, Chen S, Itoi M, Miller M, Lu L-F, Varki N, Chang AN, Broide DH, Murre C.: Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease. Nat Immunol. 2014. 15(8): 767-776.

12)Yamazaki H, Kojima N, Kato K, Hirose E, Iwasaki T, Mizui T, Takahashi H, Hanamura K, Roppongi RT, Koibuchi N, Sekino Y, Mori N, Shirao T: Spikar, a novel drebrin-binding protein, regulates

the formation and stabilization of dendritic spines. J Neurochem, 128(4):507-522, 2014.

13)Kawakita K, Okada K: Acupuncture therapy: mechanism of action, efficacy, and safety: a potential intervention for psychogenic disorders? Biopsychosoc Med. 8, 4. 2014

14)Carneiro M, Kawakita K: Re-analysis of acupuncture trials with sham interventions based on data from the Cochrane Review JAM 1:1-11, 2015

15) : -EBM -.

, 64 (1):6-12, 2014. 16)Taniguchi H, Imai K, Taniguchi S,

Kitakoji H: Acupuncture in the treatment of erectile dysfunction among a diabetic population of sildenafil citrate non-responder. Japanese Acupuncture and Moxibustion, 1:1-11, 2014

17)Shigeto M, Ramracheya R, Cha C-Y, Chibalina M, Hastoy B, Philippaert K, Rorsman N, Salehi A, Sones W, Tarasov A, Vergari E, Weston C, Johnson P-R-V, Katsura M, Vennekens R, Gallione A, Kaku K, Ladds G, Rorsman P: PKC-dependent activation of TRPM4 channels by physiological concentrations of GLP-1 evokes electrical activity and insulin secretion in mouse and human pancreatic -cells. J Clin Invest 2014, in press.

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1) Murase T, Umeda M, Fukunaga M,

Maruyama K, Kawai Y, Watanabe Y, Tanaka C, Highchi T:. Validation of the Temporal Signal Change Caused by Acupuncture Stimulation with Multi-Band Acquisition. International Society for Magnetic Resonance in Medicine, 3034. May 2014.

2) Yamashiro H, Yamatomo H, Mano H, Umeda M, Higuchi T, Saiki J Multiple neural processes underlying binocular rivalry in retinotopic visual areas. Neuroscience Nov 2014.

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J, Kinoshita S: The role of IL-6 and TNF-alfa in generating the vicious inflammatory cycle between macrophages and retinal pigment epithelium in age-related macular degeneration. 86th Annual meeting of the ARVO (Association for Research in Vision and Ophthalmology). Orlando. U.S.A. 2014.5.6


18)Mukai A, Asada K, Toda M, Yamada J, Hatanaka H, Yamagishi T, Nagata K, Ueno M, Hamuro J, Kinoshita S: The role of cell to cell interaction through extracellular microvesicles, miRNA and exosome in deregulated functions of RPE and macrophages. 86th Annual meeting of the ARVO (Association for Research in Vision and Ophthalmology). Orlando. U.S.A. 2014.5.4

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Three dimensional distribution of Pacinian corpuscles in a human toe. 2014, P435, P3-161, ,2014.9.13

26) , Meir Inbal, , , , , ,

Bagdasarian Knarik, Ahissar Ehud, Three dimensional reconstruction

of trigeminal ganglion cell processes labelled by intracellular injection; emphasis on the club-like endings.

2014, P435,P3-157, ,2014.9.13

27)Itoi M and Chiba S.: The contribution of Lymphotoxin Beta Receptor signal to the Development of cortical Thymic epithelial Cells. ThymOz : An International Workshop on Thymus Biology and T Lymphocytes. April 2nd-7th, Heron Island, Australia. 7:21. 2014.

28)

2014. 24:14. (2014.5.16-17) 29)Itoi M, Chiba S. The contribution of

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明治国際医療大学附属東洋医学研究所年報２０１４

編集者明治国際医療大学附属東洋医学研究所

発行者明治国際医療大学附属東洋医学研究所所長樋口敏宏

発行日平成27年7月31日

印刷大平印刷株式会社

明治国際医療大学附属東洋医学研究所の組織 ...>, ¹ î ± v ~3¸ s í0...

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