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Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

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Page 1: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

Energy, Catalysis and Biosynthesis

Metabolism*catabolism *anabolism

Complexity of metabolism

Review of Energy:Energy

*kinetic energy*potential energy

Page 2: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

Free energy, stability, work capacity and changeFree energy

Change in free energy =DG

Gravitational Motion

Diffusion Chemical Reaction

Page 3: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

Free energy, stability, work capacity and changeEquilibrium

*chemical equilibrium

DG = 0, no net change in the system

Chemical reactions with free energy changes:

*energetically favorable *energetically unfavorable

Page 4: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

Metabolic Disequilibrium

*Multistep open hydroelectric system

Page 5: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

EnzymesEnzymes speed up metabolic reactions:

Page 6: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

Enzymes

Enzymes are catalytic proteinsEnzymes lower the barrier of EA

Page 7: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

EnzymesInduced Fit

Page 8: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

Enzymes: How they work

Page 9: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

EnzymesPhysical and chemical properties affect enzyme activity:

*inhibitor

*cofactor

*coenzyme

*activators

Page 10: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

ATPMain types of (cellular) work:

*mechanical*transport*chemical

Page 11: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy
Page 12: Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

ATP


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