eg-018 - swgdrug · ftir atr (diamond, 3 bounce): eg-018 lot # rm-140805-03 3500 3000 2500 2000...
TRANSCRIPT
EG-018The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 1 of 5SWGDRUG.org/monographs.htmLatest Revision: 2/2/2015
N
CH3
O
1. GENERAL INFORMATION
IUPAC Name: naphthalen-1-yl(9-pentyl-9H-carbazol-3-yl)methanone
CAS#: Not Available
Synonyms: N/A
Source: DEA Reference Material Collection
Appearance: White powder
UVmax(nm): Not Determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
Form Chemical Formula Molecular Weight Melting Point (oC)
Base C28H25NO 391 97.5
EG-018The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 2 of 5SWGDRUG.org/monographs.htmLatest Revision: 2/2/2015
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~10 mg/mL in DMSO containing TMS for 0 ppm reference and maleic acid as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm
Pulse angle: 90o
Delay between pulses: 45 seconds1H NMR: EG-018 Lot # RM-140805-03; DMSO; 400MHz
8 7 6 5 4 3 2 1 0
0
1
2
3
4
5
6
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8
9
10
342216231
DMSO
H2O
TMS
Maleic Acid
1.75 1.25
342
8.5 8.0 7.5
012
34
16231
4.45 4.40
2
EG-018The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 3 of 5SWGDRUG.org/monographs.htmLatest Revision: 2/2/2015
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~4 mg/mL in chloroform.
Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25 µmCarrier Gas: Helium at 1 mL/minTemperatures: Injector: 280oC
MSD transfer line: 280oCMS Source: 230oCMS Quad: 150oCOven program:
1) 100oC initial temperature for 1.0 min2) Ramp to 300oC at 12 oC/min3) Hold final temperature for 25.0 min
Injection Parameters: Split Ratio = 25:1, 1 µL injectedMS Parameters: Mass scan range: 30-550 amu
Threshold: 100Tune file: stune.uAcquisition mode: scan
Retention Time: 25.147 minEI Mass Spectrum: EG-018 Lot # RM-140805-03
m/z35030025020015010050
[x 1
04 ]In
tens
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434343 4343434343 4343434343 4343434343 43434343555555 5555555555 5555555555 5555555555 55555555
777777 7777777777 7777777777 7777777777 77777777 101
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EI+
EG-018The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 4 of 5SWGDRUG.org/monographs.htmLatest Revision: 2/2/2015
3.3 INFRARED SPECTROSCOPY (FTIR)
Insrument: FTIR with diamond ATR attachment (3 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 8Aperture: 150
FTIR ATR (Diamond, 3 Bounce): EG-018 Lot # RM-140805-03
Wavenumber (cm-1)3500 3000 2500 2000 1500
%Tr
ansm
ittan
ce
48
56
64
72
422422422422422422422422422422422422422422422422422422422422422422
476476476476476476476476476476476476476476476476476476476476476476
521521521521521521521521521521521521521521521521521521521521521521
544544544544544544544544544544544544544544544544544544544544544544
613613613613613613613613613613613613613613613613613613613613613613
648648648648648648648648648648648648648648648648648648648648648648
719719719719719719719719719719719719719719719719719719719719719719
742742742742742742742742742742742742742742742742742742742742742742785
785785785785785785785785785785785785785785785785785785785785785
806806806806806806806806806806806806806806806806806806806806806806
910910910910910910910910910910910910910910910910910910910910910910933933933933933933933933933933933933933933933933933933933933933933
1057105710571057105710571057105710571057105710571057105710571057105710571057105710571057
11301130113011301130113011301130113011301130113011301130113011301130113011301130113011301142114211421142114211421142114211421142114211421142114211421142114211421142114211421142
119611961196119611961196119611961196119611961196119611961196119611961196119611961196119612441244124412441244124412441244124412441244124412441244124412441244124412441244124412441254
125412541254125412541254125412541254125412541254125412541254125412541254125412541254
1323132313231323132313231323132313231323132313231323132313231323132313231323132313231323
1350135013501350135013501350135013501350135013501350135013501350135013501350135013501350
1464146414641464146414641464146414641464146414641464146414641464146414641464146414641464
1481148114811481148114811481148114811481148114811481148114811481148114811481148114811481
1583158315831583158315831583158315831583158315831583158315831583158315831583158315831583
1651165116511651165116511651165116511651165116511651165116511651165116511651165116511651
284828482848284828482848284828482848284828482848284828482848284828482848284828482848284829242924292429242924292429242924292429242924292429242924292429242924292429242924292429242966296629662966296629662966296629662966296629662966296629662966296629662966296629662966
3051305130513051305130513051305130513051305130513051305130513051305130513051305130513051
Wavenumber (cm-1)1700 1600 1500 1400 1300 1200 1100 1000 900 800 700
%Tr
ansm
ittan
ce
48
56
64
72
422422422422422422422422422422422422422422422422422422422422422422
447447447447447447447447447447447447447447447447447447447447447447
476476476476476476476476476476476476476476476476476476476476476476
521521521521521521521521521521521521521521521521521521521521521521
544544544544544544544544544544544544544544544544544544544544544544
582582582582582582582582582582582582582582582582582582582582582582
613613613613613613613613613613613613613613613613613613613613613613
648648648648648648648648648648648648648648648648648648648648648648677677677677677677677677677677677677677677677677677677677677677677
719719719719719719719719719719719719719719719719719719719719719719
742742742742742742742742742742742742742742742742742742742742742742
771771771771771771771771771771771771771771771771771771771771771771
785785785785785785785785785785785785785785785785785785785785785785
806806806806806806806806806806806806806806806806806806806806806806
910910910910910910910910910910910910910910910910910910910910910910933933933933933933933933933933933933933933933933933933933933933933
10571057105710571057105710571057105710571057105710571057105710571057105710571057105710571072107210721072107210721072107210721072107210721072107210721072107210721072107210721072
11301130113011301130113011301130113011301130113011301130113011301130113011301130113011301142114211421142114211421142114211421142114211421142114211421142114211421142114211421142
1155115511551155115511551155115511551155115511551155115511551155115511551155115511551155
1196119611961196119611961196119611961196119611961196119611961196119611961196119611961196
12441244124412441244124412441244124412441244124412441244124412441244124412441244124412441254
125412541254125412541254125412541254125412541254125412541254125412541254125412541254
12791279127912791279127912791279127912791279127912791279127912791279127912791279127912791323
132313231323132313231323132313231323132313231323132313231323132313231323132313231323
1350135013501350135013501350135013501350135013501350135013501350135013501350135013501350143914391439143914391439143914391439143914391439143914391439143914391439143914391439143914541454145414541454145414541454145414541454145414541454145414541454145414541454145414541464146414641464146414641464146414641464146414641464146414641464146414641464146414641464
1481148114811481148114811481148114811481148114811481148114811481148114811481148114811481
1583158315831583158315831583158315831583158315831583158315831583158315831583158315831583
16161616161616161616161616161616161616161616161616161616161616161616161616161616161616161651
165116511651165116511651165116511651165116511651165116511651165116511651165116511651
EG-018The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 5 of 5SWGDRUG.org/monographs.htmLatest Revision: 2/2/2015
4. ADDITIONAL RESOURCES
No resources identified as of 2/2/15.