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CURRICULUM VITAE Elise Feng-i Morgan Department of Mechanical Engineering Boston University Tel: (617) 353-2791 110 Cummington Mall Fax: (617) 353-5866 Boston, MA 02215 Email: [email protected] Research Areas Orthopaedic biomechanics and mechanobiology: Current focus is on biomechanics of vertebral fractures, biomechanics of fracture healing, mechanobiology of skeletal regeneration, computed tomography for composite imaging of multiple soft and hard tissues, and microscale mechanical properties of bone. Education and Training 2002-03 Postdoctoral Researcher, Department of Mechanical Engineering, Stanford University 2002 Ph.D., Mechanical Engineering, University of California, Berkeley 2000 M.S., Mechanical Engineering, University of California, Berkeley 1996 B.S., Mechanical Engineering, Stanford University Positions 2018-19 Associate Dean for Research and Technology Development ad interim, College of Engineering, Boston University 2015- Professor, Dept. of Mechanical Engineering, Dept. of Biomedical Engineering, Division of Materials Science, Boston University 2010-11 Visiting Associate Research Scientist, Institute for Engineering in Medicine, University of California San Diego (sabbatical visit) 2010- Director, Micro-Computed Tomography Imaging Core Facility, Boston University 2009-15 Associate Professor, Dept. of Mechanical Engineering, Dept. of Biomedical Engineering, Boston University 2003- Adjunct Assistant Professor, Dept. of Orthopaedic Surgery, Boston University School of Medicine 2003-09 Assistant Professor, Dept. of Mechanical Engineering (formerly, Dept. of Aerospace & Mechanical Engineering), Boston University 1999-02 Engineering Consultant, Supracor, Inc., San Jose, California 1996-97 Mathematics Teacher, The Pingry School, Martinsville, New Jersey Honors 2016-18 Chair, National Institutes of Health Study Section: Skeletal Biology, Structure, and Regeneration 2015- Fellow, American Institute for Medical and Biological Engineering 2015 100 Inspiring Women in STEM, Insight into Diversity 2014-16 Member, National Institutes of Health Study Section: Skeletal Biology, Structure, and Regeneration 2014 Faculty Service Award, College of Engineering, Boston University 2013 Kappa Delta Young Investigator Award, American Academy of Orthopaedic Surgeons 2012-17 Distinguished Faculty Fellow, College of Engineering, Boston University 2010-11 Ruth L. Kirschstein National Research Service Award for Senior Fellows, National

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Page 1: EFMcv full 2018 10 - Boston UniversityJournal of Biomechanical Engineering, 2011; 137: 071001. 34. Baloul, SS, Gerstenfeld, LC, Morgan, EF, Carvalho, RS, Van Dyke, TE, Kantarci, A

CURRICULUM VITAE Elise Feng-i Morgan Department of Mechanical Engineering Boston University Tel: (617) 353-2791 110 Cummington Mall Fax: (617) 353-5866 Boston, MA 02215 Email: [email protected] Research Areas Orthopaedic biomechanics and mechanobiology: Current focus is on biomechanics of vertebral fractures, biomechanics of fracture healing, mechanobiology of skeletal regeneration, computed tomography for composite imaging of multiple soft and hard tissues, and microscale mechanical properties of bone. Education and Training 2002-03 Postdoctoral Researcher, Department of Mechanical Engineering, Stanford University 2002 Ph.D., Mechanical Engineering, University of California, Berkeley 2000 M.S., Mechanical Engineering, University of California, Berkeley 1996 B.S., Mechanical Engineering, Stanford University

Positions 2018-19 Associate Dean for Research and Technology Development ad interim, College of

Engineering, Boston University 2015- Professor, Dept. of Mechanical Engineering, Dept. of Biomedical Engineering,

Division of Materials Science, Boston University 2010-11 Visiting Associate Research Scientist, Institute for Engineering in Medicine,

University of California San Diego (sabbatical visit) 2010- Director, Micro-Computed Tomography Imaging Core Facility, Boston University 2009-15 Associate Professor, Dept. of Mechanical Engineering, Dept. of Biomedical

Engineering, Boston University 2003- Adjunct Assistant Professor, Dept. of Orthopaedic Surgery, Boston University School

of Medicine 2003-09 Assistant Professor, Dept. of Mechanical Engineering (formerly, Dept. of Aerospace

& Mechanical Engineering), Boston University 1999-02 Engineering Consultant, Supracor, Inc., San Jose, California 1996-97 Mathematics Teacher, The Pingry School, Martinsville, New Jersey

Honors 2016-18 Chair, National Institutes of Health Study Section: Skeletal Biology, Structure, and

Regeneration 2015- Fellow, American Institute for Medical and Biological Engineering 2015 100 Inspiring Women in STEM, Insight into Diversity 2014-16 Member, National Institutes of Health Study Section: Skeletal Biology, Structure, and

Regeneration 2014 Faculty Service Award, College of Engineering, Boston University 2013 Kappa Delta Young Investigator Award, American Academy of Orthopaedic Surgeons 2012-17 Distinguished Faculty Fellow, College of Engineering, Boston University 2010-11 Ruth L. Kirschstein National Research Service Award for Senior Fellows, National

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Institutes of Health 2009 Early Career Research Excellence Award, College of Engineering, Boston University 2006 Young Investigator Research Award, International Osteoporosis Foundation and

Servier Research Group 2000 Outstanding Graduate Student Instructor Award, University of California, Berkeley 1999 First Place, American Society of Mechanical Engineers Master’s Paper Competition 1997-00 National Science Foundation Graduate Research Fellowship 1996 Phi Beta Kappa Honors Society 1996 Tau Beta Pi Engineering Honors Society 1995 Lincoln Arc Welding Foundation Award 1995 Stanford Summer Undergraduate Research Fellowship 1993 President’s Award, Stanford University

Publications and Presentations (http://scholar.google.com/citations?user=hLf0lzEAAAAJ&hl=en) (http://www.ncbi.nlm.nih.gov/sites/myncbi/1na7kuP26in55/bibliography/40727813/public/?sort=date&direction=descending)

Peer-Reviewed Journal Articles and Peer-Reviewed Proceedings 1. Kaiser, JM, Allaire, B, Fein, PM, Lu, D, Jarraya, M, Guermazi, A, Demissie, S, Samelson, EJ,

Bouxsein, ML, Morgan, EF. Correspondence between bone mineral density and intervertebral disc degeneration across age and sex. In press, Archives of Osteoporosis.

2. Watt, J, Baker, AH, Meeks, B, Divieti Pajevic, P, Morgan, EF, Gerstenfeld, LC, Schlezinger, J. Tributyltin induces distinct effects on cortical and trabecular bone in female C57Bl/6J mice. Journal of Cellular Physiology, 2018; Jan 30 [Epub ahead of print].

3. Hussein, AI, Louzeiro, DT, Unnikrishnan, GU, Morgan, EF. Differences in trabecular microstructure and simplified boundary conditions limit the accuracy of QCT-based finite element models of vertebral failure. Journal of Biomechanical Engineering, 2018; 140(2).

4. Cooke, ME, Hussein, AI, Lybrand, KE, Wulff, A, Simmons, E, Choi, JH, Litrenta, J, Ricci, WM, Nascone, JW, O’Toole, RV, Morgan, EF, Gerstenfeld, LC. Correlation between RUST assessments of fracture healing to structural and biomechanical properties. Journal of Orthopaedic Research, 2018; 36(3):945-53.

5. Fein, PM, DelMonaco, A, Jackman, TM, Curtiss, C, Guermazi, A, Barest, GD, Morgan, EF. Is bone density associated with intervertebral disc pressure in healthy and degenerated discs? Journal of Biomechanics, 2017; 64:41-48.

6. Drenkard, LMM, Kupratis, ME, Li, K, Gerstenfeld, LC, Morgan, EF. Local changes to the distal femoral growth plate following injury in mice. Journal of Biomechanical Engineering, 2017; 139(7).

7. Bragdon, B, Lam, S, Aly, S, Femia, A, Clark, A, Hussein, AI, Morgan EF, Gerstenfeld, LC. Earliest phases of chondrogenesis are dependent upon angiogenesis during ectopic bone formation in mice. Bone, 2017; 101:49-61.

8. Jackman, TM, DelMonaco, AM, Morgan, EF. Accuracy of finite element analyses of CT scans in predictions of vertebral failure patterns under axial compression and anterior flexion. Journal of Biomechanics, 2016; 49(2):267-75.

9. Morgan, EF, Pittman, J, DiGiacomo, A, Cusher, D, de Bakker, CMJ, Mroszczyk, KA, Grinstaff, MW, Gerstenfeld, LC. BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing. Journal of Orthopaedic Research, 2016; 34(12):2096-2105.

10. Jackman, TM, De Barros, L, Camp, A, Curtiss, C, Hussein, AI, Morgan, EF. Quantitative, 3-D visualization of the initiation and progression of vertebral fractures under compression and anterior flexion. Journal of Bone and Mineral Research, 2016; 31(4):777-88.

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11. Alsofi, L, Daley, E, Morgan, EF, Mason, ZD, Acevedo, JF, Word, RA, Gerstenfeld, LC, Trackman, PC. Sex-linked phenotype of lysyl oxidase like-1 mutant mice. Calcified Tissue International, 2016;98(2):172-85.

12. Scanlon, V, Soung do, Y, Adapala, NS, Morgan, EF, Hansen, MF, Drissi, H, Sanjay, A. Role of Cbl-Pl3K interaction during skeletal remodeling in a murine model of bone repair. PLoS One, 2015; 10(9):e0138194.

13. Unnikrishnan, GU, Gallagher, JA, Hussein, AI, Barest, GD, Morgan, EF. Elastic anisotropy of trabecular bone in the elderly human vertebra. Journal of Biomechanical Engineering, 2015; 137(11).

14. Miller, GJ, Gerstenfeld, LC, Morgan, EF. Mechanical microenvironments and protein expression associated with formation of different skeletal tissues during bone healing. Biomechanics and Mechanobiology, 2015;14(6):1239-53.

15. Zigdon-Giladi, H, Bick, T, Morgan, EF, Lewinson, D, Machtei, EE. Peripheral blood-derived endothelial progenitor cells enhance vertical bone formation. Clinical Implant Dentistry and Related Research, 2015; 17(1):83-92.

16. Bragdon, B, Burns, R, Baker, AH, Belkina, AC, Morgan, EF, Denis, GV, Gerstenfeld, LC, Schlezinger, JJ. Intrinsic sex-linked variations in osteogenic and adipogenic differentiation potential of bone marrow multipotent stromal cells. Journal of Cellular Physiology, 2014; 230(2):296-307.

17. Jackman, TJ, Hussein, AI, Adams, A, Makhnejia, K, Morgan, EF. Endplate deflection is a defining feature of vertebral fracture and is associated with properties of the underlying trabecular bone. Journal of Orthopaedic Research, 2014;32(7):880-6.

18. Al-Sebaei, MO, Daukss, DM, Belkina, AC, Kaker, S, Wigner, NA, Cusher, D, Graves, D, Einhorn, T, Morgan, EF, Gerstenfeld, LC. Role of Fas and Treg cells in fracture healing as characterized in the fas-deficient (lpr) mouse model of lupus. Journal of Bone and Mineral Research, 2014; 29(6):1478-91.

19. Wu, Y, Tu, Q, Valverde, P, Zhang, J, Murray, D, Dong, LQ, Cheng, J, Jiang, H, Rios, M, Morgan E, Tang, Z, Chen, J. Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice. American Journal of Physiology - Endocrinology and Metabolism, 2014; 306(12):E1418-30.

20. Hasturk, H, Kantarci, A, Ghattas, M, Dangaria, SJ, Abdallah, R, Morgan, EF, Diekwisch, TG, Ashman, A, VanDyke, T. The use of light/chemically-hardened poly-methylmethacyrlate, poly-hydroxyl-ethyl-methacrylate and calcium hydroxide graft material in combination with polyanhydride around implants and extraction sockets in minipigs: part II: histological and µCT evalulations. J Periodontology, 2014; 85(9):1230-9.

21. Unnikrishnan, GU, Barest, G, Berry, DB, Hussein, AI, Morgan, EF. Effect of specimen-specific anisotropic material models in QCT-based finite element analysis of vertebra. Journal of Biomechanical Engineering, 2013; 135(10):101007-11.

22. Hussein, AI, Jackman, TM, Morgan, SR, Barest, GD, Morgan, EF. The intra-vertebral distribution of bone density: correspondence to intervertebral disc health and implications for vertebral strength. Osteoporosis International, 2013; 24(12):3021-30.

23. Kuo, S, DeSilva, JM, Devlin, MJ, McDonald, G, Morgan, EF. The effect of the Achilles tendon on trabecular structure in the primate calcaneus. Anatomical Record, 2013; 296(10):1509-17.

24. Hussein, AI, Mason, ZD, Morgan, EF. Presence of intervertebral discs alters observed stiffness and failure mechanisms in the vertebra. Journal of Biomechanics, 2013; 46(1):1683-8.

25. Papadopoulos, G, Weinberg, EO, Massari, P, Gibson, FC 3rd, Wetzler, LM, Morgan, EF, Genco CA. Macrophage-Specific TLR2 Signaling Mediates Pathogen-Induced TNF-Dependent Inflammatory Oral Bone Loss. Journal of Immunology, 2013; 190(3):1148-57.

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26. Hayward, LNM, de Bakker, CMJ, Gerstenfeld, LC, Grinstaff, MW and Morgan, EF. Assessment of contrast-enhanced computed tomography for imaging of cartilage during fracture healing. Journal of Orthopedic Research, 2013; 31(4):567-73.

27. Hussein, AI and Morgan, EF. The effect of intra-vertebral heterogeneity in microstructure on vertebral strength and failure patterns. Osteoporosis International, 2013; 24(3):979-89.

28. Morgan, EF, Hussein, AI, Al-Awadhi, BA, Hogan, DE, Matsubara, H, Al-Aq, Z, Fitch, JS, Andre, A, Hosur, K, Gerstenfeld, LC. Vascular development during distraction osteogenesis proceeds by sequential intramuscular arteriogenesis followed by intraosteal angiogenesis. Bone, 2012, 51(3):535-45.

29. Hussein, AI, Barbone, PE, Morgan, EF. Digital volume correlation for study of the mechanics of whole bones. Procedia of the International Union of Theoretical and Applied Mechanics, 2012; 4:116-125.

30. Matsubara, H, Hogan, DE, Morgan, EF, Mortlock, DP, Einhorn, TA, Gerstenfeld, LC. Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis bone. Bone, 2012; 51(1):168-80.

31. Hayward, LNM, de Bakker, CMJ, Lusic, H, Gerstenfeld, LC, Grinstaff, MW, Morgan, EF. Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing. Microscopy Research and Technique, 2012; 75(1): 7-14.

32. Shore, SW, Barbone, PE, Oberai, AA, and Morgan, EF. Transversely isotropic elasticity imaging of cancellous bone. Journal of Biomechanical Engineering, 2011; 133:0 61002.

33. Unnikrishnan, GU and Morgan, EF. A new material mapping procedure for QCT-based, continuum finite element analyses of the vertebra. Journal of Biomechanical Engineering, 2011; 137: 071001.

34. Baloul, SS, Gerstenfeld, LC, Morgan, EF, Carvalho, RS, Van Dyke, TE, Kantarci, A. Mechanism of action and morphological changes in the alveolar bone in response to selective alveolar decortication facilitated tooth movement. American Journal of Orthodontics and Dentofacial Orthopedics, 2011; 139(4 Suppl):S83-101. Winner of the 2010 American Association of Orthodontists Milo Hellman Research Award

35. Nowlan, N, Jepsen, KJ, Morgan, EF. Smaller, weaker and less stiff bones evolve from changes in subsistence strategy. Osteoporosis International, 2011; 22(6):1967-80.

36. Morgan, EF, Salisbury Palomares, KT, Gleason, RE, Bellin, DL, Chien, KB. Correlations between local strains and tissue phenotypes in an experimental model of skeletal healing. Journal of Biomechanics, 2010; 43(12): 2418-24.

37. Miller, GE and Morgan, EF. Use of microindentation to characterize the mechanical properties of articular cartilage: comparison of biphasic material properties across length scales. Osteoarthritis and Cartilage, 2010; 18(8): 1051-7.

38. Salisbury Palomares, KT, Gerstenfeld, LC, Wigner, NA, Lenburg, ME, Einhorn, TA, Morgan, EF. Transcriptional profiling and biochemical analysis of mechanically induced cartilaginous tissues. Arthritis and Rheumatism, 2010; 62(4): 1108-18.

39. Leong, PL and Morgan, EF. Correlations between indentation modulus and mineral density in bone-fracture calluses. Integrative and Comparative Biology, 2009; 49: 59-68.

40. Cuomo, AV, Virk, M, Petrigliano, F, Morgan, EF, Lieberman, JR. Mesenchymal stem cell concentration and bone repair: potential pitfalls from bench to bedside. Journal of Bone and Joint Surgery, 2009; 91A(5): 1073-83.

41. Bais MV, Wigner, N, Young, M, Toholka, R, Graves, DT, Morgan, EF, Gerstenfeld, LC, Einhorn, TA. BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells. Bone, 2009; 45(2): 254-66.

42. Kim, HK, Bian, H, Aya-ay, J, Garces, A, Morgan, EF, Gilbert, SR. Hypoxia and HIF-1alpha expression in the epiphyseal cartilage following ischemic injury to the immature femoral head.

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Bone, 2009; 45(2): 280-8. 43. Gaur, T, Wixted, JJ, Hussain, S, O’Connel, S, Morgan, EF, Ayers, D, Komm, BS, Bodine, PV,

Stein, GS, Lian, JB. Secreted frizzled related protein 1 is a target to improve fracture healing. Journal of Cellular Physiology, 2009; 220(1): 174-181.

44. Hunter, DJ, Gerstenfeld, LC, Bishop, G, Mason, ZD, Einhorn, TA, Maciewicz, RA, Newham, P, Morgan, EF. Bone marrow lesions from osteoarthritic knees are characterized by sclerotic bone that is less well mineralized. Arthritis Research and Therapy, 2009; 11(1): R11.

45. Salisbury Palomares, KT, Gleason, RE, Mason, ZD, Cullinane, DM, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Mechanical stimulation alters tissue differentiation and molecular expression during bone healing. Journal of Orthopaedic Research, 2009; 27(9):1123-32.

46. Hayward, LNM and Morgan, EF. Assessment of a mechano-regulation theory of skeletal tissue differentiation in an in vivo model of mechanically induced cartilage formation. Biomechanics and Modeling in Mechanobiology, 2009; 8(6): 447-455.

47. Gerstenfeld, LC, Sacks, DJ, Pelis, M, Mason, ZD, Graves, DT, Barrero, M, Ominsky, M, Kostenuik, PJ, Morgan, EF, Einhorn, TA. Comparison of bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing. Journal of Bone and Mineral Research, 2009; 24(2): 196-208.

48. Morgan, EF, Chien, KB, Mason, ZD, Pfeiffer, AJ, Barnes, GL, Einhorn, TA, Gerstenfeld, LC. Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function. Bone, 2009; 44(2): 225-44.

49. Morgan, EF, Mason, ZD, Bishop, G, Davis, AD, Gerstenfeld, LC, Einhorn, TA. Combined effects of recombinant human BMP-7 (rhBMP-7) and parathyroid hormone (1-34) in metaphyseal bone healing. Bone, 2008; 43(6):1031-8.

50. Leong PL and Morgan, EF. Measurement of fracture callus material properties via nanoindentation. Acta Biomaterialia, 2008; 4(5):1569-1575.

51. Kaufman, JD, Miller, GE, Morgan, EF, Klapperich, CM. Time-dependent mechanical characterization of poly(2-hydroxyethyl methacrylate) hydrogels using nanoindentation and confined compression. Journal of Materials Research, 2008; 23(5):1472-1481.

52. Jacobsen, KA, Alaql, ZS, Fitch, J, Mason, ZD, Cole, RM, Gilbert, SR, Clemens, TL, Morgan, EF, Einhorn, TA, Gerstenfeld, LC. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. Journal of Bone and Mineral Research, 2008; 23(5); 596-609.

53. Morgan, EF, Gleason, RE, Leong, PL, Hayward, LN, Salisbury Palomares, KT. Mechanotransduction and fracture repair. Journal of Bone and Joint Surgery, 2008; 90(2):S25-90.

54. Houtchens, GR, Foster, MD, Desai, TA, Morgan, EF, Wong, JY. Combined effects of microtopography and cyclic strain on vascular smooth muscle cell orientation. Journal of Biomechanics, 2008; 41(4): 762-9.

55. Kakar, S, Einhorn, TA, Vora, S, Miara, LJ, Hohn, G, Tobin, D, Jacobsen, KA, Al-Sebaei, MO, Song, M, Trackman, P, Morgan, EF, Gerstenfeld, LC, Barnes, GL. Enhanced chondrogenesis and wnt-signaling in parathyroid hormone treated fractures. Journal of Bone and Mineral Research, 2007; 22(12):1903-12.

56. Liu, L and Morgan, EF. Accuracy and precision of digital volume correlation in quantifying displacements and strains in trabecular bone. Journal of Biomechanics, 2007; 40(15):3516-20.

57. Tsiridis, E, Morgan, EF, Bancroft, JM, Song, M, Kain, M, Gerstenfeld, LC, Einhorn, TA, Bouxsein, ML, Tornetta, P 3rd. Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing. Journal of Orthopaedic Research, 2007; 25(9): 1193-203.

58. Kayal, RA, Tsatsas, D, Bauer, MA, Allen, B, Al-Sebaei, MO, Kakar, S, Leone, CW, Morgan, EF, Gerstenfeld L, Einhorn TA, Graves DT. Diminished bone formation during diabetic fracture

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healing is related to the premature resorption of cartilage associated with increased osteoclast activity. Journal of Bone and Mineral Research, 2007; 22(4): 560-8.

59. Morgan, EF, Longaker, MT, Carter, DR. Relationships between tissue dilatation and differentiation in distraction osteogenesis. Matrix Biology, 2006; 25(2): 94-103.

60. Morgan, EF, Yeh, OC, Keaveny, TM. Damage in trabecular bone at small strains. European Journal of Morphology, 2005; 42(1-2): 13-21.

61. Morgan, EF, Lee, JJ, and Keaveny, TM. Sensitivity of multiple damage parameters to compressive overload in cortical bone. Journal of Biomechanical Engineering, 2005; 127(4): 557-562.

62. Li, S and Morgan, EF. Effective elastic moduli of two-dimensional solids with distributed cohesive microcracks. European Journal of Mechanics A/Solids, 2004; 23(6): 925-933.

63. Morgan, EF, Bayraktar, HH, Yeh, OC, Majumdar, S, Burghardt, A, and Keaveny, TM. Contribution of inter-site variations in architecture to trabecular bone apparent yield strain. Journal of Biomechanics, 2004; 37(9): 1413-1420.

64. Salim, A, Nacamuli, RP, Morgan, EF, Giaccia, AJ, Longaker, MT. Transient changes in oxygen tension inhibit osteogenic differentiation and runx2 expression in osteoblasts. J Biological Chemistry 2004; 279(38):40007-40016.

65. Khurana, RN, Baudendistel, TE, Morgan, EF, Rabkin, RA, Elkin, RB, and Aalami, OO. Postoperative rhabdomyolysis following laparoscopic gastric bypass in the morbidly obese. Archives of Surgery, 2004; 139(1): 73-76.

66. Bayraktar, HH, Morgan, EF, Morris, GM, Wong, EK, and Keaveny, TM. Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue. Journal of Biomechanics, 2004; 37(1): 27-35.

67. Li, S and Morgan, EF. Micromechanics modeling of plastic yielding in a solid containing mode III cohesive cracks. International Journal of Fracture, 2003; 120(1-2): L105-L112.

68. Morgan, EF, Bayraktar, HH, and Keaveny, TM. Trabecular bone modulus-density relationships depend on anatomic site. Journal of Biomechanics 2003; 36(7): 897-904.

69. Kopperdahl, DL, Morgan, EF, Keaveny, TM. Quantitative computed tomography estimates of the mechanical properties of human vertebral bone. Journal of Orthopaedic Research, 2002; 20(4): 801-5.

70. Morgan, EF and Keaveny, TM. Dependence of yield strain of human trabecular bone on anatomic site. Journal of Biomechanics, 2001; 34(5): 569-577.

71. Morgan, EF, Yeh, OC, Chang, WC, Keaveny, TM. Nonlinear behavior of trabecular bone at small strains. Journal of Biomechanical Engineering, 2001; 123(1): 1-9.

72. Morgan, EF, Yetkinler, DN, Constantz, BR, Dauskardt, RH. Mechanical properties of a carbonated hydroxyapatite bone mineral substitute. Journal of Materials Science: Materials in Medicine, 1997; 8(9): 559-570.

Book Chapters and Review Articles 1. Morgan, EF, Unnikrishnan, GU, Hussein, AI. Bone mechanical properties in healthy and

diseased states. In press, Annual Reviews in Biomedical Engineering. 2. Morgan, EF, Hussein, AI, and Einhorn, TA. Biomechanics of fracture healing. In: Rosen, CJ,

editor. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 9th edition. Wiley; In press.

3. Osheroff, G, Morgan, EF, Shefelbine, SJ, Karim, L, McNamara, LM, Augat, P. Bone mechanical properties and changes with osteoporosis. Injury, 2016; 42(S2):S11-20.

4. Morgan, EF and Lei, J. Toward clinical application and molecular understanding of the mechanobiology of bone healing. Clinical Reviews in Bone and Mineral Metabolism, 2015; 13:256-265.

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5. Augat, P, Morgan, EF, Lujan, TJ, MacGillivray, TJ, Cheung, WH. Imaging techniques for the assessment of fracture repair. Injury, 2014; 45(Suppl 2):S16-22.

6. Jackman, TM, McDonald, G, Morgan, EF. MicroCT Imaging of Bone Tissue. Simpson, H and Augat, P, editors. Experimental Research Methods: A Guidebook for Studies in Osteosynthesis, 2015; Thieme, 480 pp.

7. Morgan, EF, De Giacomo, A, Gerstenfeld, LC. Overview of skeletal repair (fracture healing and its assessment). Methods in Molecular Biology, 2014; 1130:13-31.

8. De Giacomo, A, Morgan, EF, Gerstenfeld, LC. Generation of closed transverse fractures in small animals. Methods in Molecular Biology, 2014; 1130:35-44.

9. Morgan, EF and Einhorn, TA. Biomechanics of Fracture Healing. In: Rosen, CJ, editor. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th edition. Wiley; 2013; pp 99-105.

10. Morgan, EF, Barnes, GL, Einhorn, TA. The Bone Organ System: Form and Function. In: Marcus, R, Feldman, D, Nelson, D, Rosen, CJ, editors. Osteoporosis, 4th edition. Boston: Elsevier Academic Press; 2013; pp. 3-20.

11. Karim, L, Hussein, AI, Morgan, EF, Bouxsein, ML. The Mechanical Behavior of Bone. In: Marcus, R, Feldman, D, Nelson, D, Rosen, CJ, editors. Osteoporosis, 4th edition. Boston: Elsevier Academic Press; 2013; pp. 431-452.

12. Shore, SW, Unnikrishnan, GU, Hussein, AI, Morgan, EF. Bone Biomechanics. In: Winkelstein, BA, editor. Orthopaedic Biomechanics. Boca Raton: CRC/Taylor and Francis; 2012; pp. 3-47.

13. Sibai, T, Morgan, EF, Einhorn, TA. Effect of Anabolic Agents on Bone Quality. In: Boskey, A and Donnelly, E, editors. Bone Quality: From Bench to Bedside. Clinical Orthopaedics and Related Research, 2011; 469(8):2215-2224.

14. Morgan, EF and Einhorn, TA. Biomechanics of Fracture Healing. In: Rosen, CJ, editor. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th edition. Wiley; 2008; pp 65-69.

15. Morgan, EF and Bouxsein, ML. Biomechanics of Bone and Age-Related Fractures. In: Bilezikian, JP, Raisz, LG, Martin, J, editors. Principles of Bone Biology, 3rd edition. Boston: Elsevier Academic Press; 2008; pp. 29-51.

16. Barnes, GL, Kakar, S, Vora, S, Morgan, EF, Gerstenfeld, LC, Einhorn, TA. Stimulation of fracture healing with systemic intermittent parathyroid hormone treatment. Journal of Bone and Joint Surgery, 2008; 90(Suppl 1): 120-7.

17. Morgan, EF, Barnes, GL, Einhorn, TA. The Bone Organ System: Form and Function. In: Marcus, R, Feldman, D, Nelson, D, Rosen, CJ, editors. Osteoporosis, 3rd edition. Boston: Elsevier Academic Press; 2008; pp. 3-25.

18. Morgan, EF and Bouxsein, ML. Use of Finite Element Analysis to Assess Bone Strength. BoneKey-Osteovision Perspectives, 2005; 2(12): 8-19 (http://www.bonekey-ibms.org/cgi/content/full/ibmske)

19. Keaveny, TM, Morgan, EF, Yeh, OC. Bone Mechanics. In: Kurtz, M, editor. Standard Handbook of Biomedical Engineering and Design, McGraw Hill, New York, 2003, pp 8.1-8.23.

20. Keaveny, TM, Morgan, EF, Niebur, GL, Yeh, OC. Biomechanics of Trabecular Bone. Annual Reviews in Biomedical Engineering, Vol 3: 307-333, 2001.

Thesis Morgan, EF. The dependence of structure-function relationships for human trabecular bone on anatomic site. University of California, Berkeley, 2002.

Selected Conference Presentations 1. Kupratis ME, Mangano Drenkard LM, Gerstenfeld LC, Morgan EF. Role of the A2B Adenosine

Receptor in Inflammatory Degradation of Cartilage. Annual Meeting of the American Society for

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Bone and Mineral Research, 2018. 2. Samelson EL, Jarraya M, Yau X, Morgan EF, Bouxsein ML, Kiel DP, Travison, Suri P,

Guermazi A. Older adults with greater severity of lumbar disc height narrowing and facet joint osteoarthritis have higher lumbar volumetric BMD, independently of body weight: Framingham QCT Study. Annual Meeting of the American Society for Bone and Mineral Research, 2018.

3. Kaiser JM, Ba C, Ching JM, Mertz JC, Barbone PE, Morgan EF. Correspondence between cellular strains and morphology within the bone fracture callus. World Congress of Biomechanics, 2018.

4. Morgan, EF, DelMonaco, A, Fein, PM, Jackman, TM. Effects of disc degeneration on endplate stresses and vertebral failure. World Congress of Biomechanics, 2018.

5. Hussein AI, Morgan, EF, Gerstenfeld, LC. Genetic variability in fracture healing under phosphate deficiency at the tissue and molecular levels. World Congress of Biomechanics, 2018.

6. Kaiser, JM, Ba, C, Ching, JM, Mertz, JC, Barbone, PE, Morgan EF. Experimental measures of cellular strains and their relation to cell morphology within the bone fracture callus. Annual Meeting of the Orthopaedic Research Society, 2018.

7. Wu, Y, Unnikrishnan, G, Hussein, AI, Morgan, EF. Under physiologic boundary conditions, finite element analyses based on quantitative computed tomography scans do not require trabecular fabric for accurate modeling of vertebral mechanical behavior. Annual Meeting of the Orthopaedic Research Society, 2018.

8. Morgan, EF, Jackman TM, Hussein, AI, Wu, Y. Sex-related differences in bone microstructure adjacent to the intervertebral disc: correspondence to spine fracture. 4th International Spine Research Symposium, 2017.

9. Morgan, EF, Jackman, TM, Hussein, AI, Curtiss, CC. Sex-related differences in endplate porosity and their correspondence to vertebral strength. Annual Meeting of the American Society for Bone and Mineral Research, 2017.

10. Bragdon, B, Bennie, A, Lei, J, Morgan, EF, Gerstenfeld, LC. Prx-1 embryonic specification is retained in a postnatal regenerative stem cell population that gives rise to skeletal, fat, and vascular tissues. Annual Meeting of the American Society for Bone and Mineral Research, 2017.

11. Deng, ZJ, Hussein, AI, Lybrand, K, Carrol, D, Wulff, A, Matheny, H, Hogue, B, Demissie, S, Morgan, EF, Gerstenfeld, LC. Correlations between transcriptomic gene expression and bone phenotype in a phosphate-deficient, mouse fracture healing model. Annual Meeting of the American Society for Bone and Mineral Research, 2017.

12. Loaiza, J, Hussein, AI, Morgan, EF. Experimental measurement of multiaxial strain states and multiaxial yielding of trabecular bone during vertebral failure. Summer Biomechanics, Bioengineering, and Biotransport Conference, 2017.

13. Kaiser, JM, Allaire, B, Fein, PM, Demissie, S, Samelson, EJ, Bouxsein, ML, Morgan, EF. Correspondence between bone mineral density and intervertebral disc degeneration across age and sex. Annual Meeting of the Orthopaedic Research Society, 2017.

14. Wu, YQ, Jackman, TM, Morgan, EF. Tissue yielding and the accuracy of QCT-based FE models of vertebral failure. Annual Meeting of the Orthopaedic Research Society, 2017.

15. Guang, Y, Lybrand, K, Desautels, J, Gikas, KP, Wise, A, Silvia, B, Gerstenfeld, LC, Morgan, EF. Age- and sex-related characteristics of bone cysts in hip osteoarthritis. Annual Meeting of the Orthopaedic Research Society, 2017.

16. Mangano Drenkard, LM, Oberfeld, BE, Shimizu, RD, Rapp, EG, Gerstenfeld, LC, Morgan, EF. Role of the a2b adenosine receptor in the degradation of bone and cartilage in collagen antibody-induced arthritis. Annual Meeting of the Orthopaedic Research Society, 2017.

17. Hussein, AI, Cooke, ME, Lybrand, KE, Choi, JH, Litrenta, J, Ricci, WM, Nascone, JW, O’Toole, RV, Morgan, EF, Tornetta, P, Gerstenfeld, LC. Relationship between radiographic methods of scoring of fracture healing and the structural, biomechanical progression of healing. Annual

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Meeting of the Orthopaedic Research Society, 2017. 18. Veltre, DR, Chen, E, Hussein, AI, Huang, C, Morgan, EF, Schlezinger, J, Gerstenfeld, LC. High-

fat diet leads to decreased fracture healing in mice model. Annual Meeting of the Orthopaedic Research Society, 2017.

19. Mangano, LM, Kupratis, ME, Li, K, Rapp, EG, Gerstenfeld, LC, Morgan, EF. Local changes to the growth plate in response to injury. Summer Biomechanics, Bioengineering, and Biotransport Conference, 2016. 3rd place in PhD Student Paper Competition (category: Imaging)

20. Fein, PM, DelMonaco, AM, Jackman, TM, Guermazi, A, Curtiss, CT, Morgan, EF. Dependence of regional variations in vertebral endplate density and intervertebral disc pressure on disc degeneration. Annual Meeting of the Orthopaedic Research Society, 2016.

21. Morgan, EF, Allaire, B, Fein, P, Lu, D, Adams, A, Kiel, D, Demissie, S, Samelson, E, Bouxsein, M. Intravertebral heterogeneity of lumbar vertebral trabecular bone density is associated with vertebral fracture independently of average BMD. Annual Meeting of the American Society for Bone and Mineral Research, 2015.

22. Johannesdottir, F, Awale, A, Fein, P, Allaire, B, McLean, RR, Broe, KE, Samelson, EJ, Kiel, DP, Morgan, EF, Bouxsein, ML. Intravertebral Heterogeneity of Lumbar Vertebral Trabecular Bone Density Assessed from in vivo QCT is Weakly Associated with Lumbar Spine TBS Measured by DXA. Annual Meeting of the American Society for Bone and Mineral Research, 2015.

23. Hussein, A, Wulff, A, Matheny, H, Hogue, B, Lybrand, K, DeGiacomo, A, Gerstenfeld, L, Morgan, EF. Genetic Variability in Fracture Healing Under Phosphate Deficiency. Annual Meeting of the American Society for Bone and Mineral Research, 2015.

24. Bragdon, B, Cheng, T, Morgan, EF, Kalajzic, I, Harris, SE, Gerstenfeld, LC. BMP2 Regulates Both Osteogenesis and Angiogenesis. Annual Meeting of the American Society for Bone and Mineral Research, 2015.

25. Bragdon, B, Lam, S, Aly, S, Morgan, EF, Gerstenfeld, L. Angiogenesis is Required for the Earliest Phases of Chondrogenesis During Ectopic Bone Formation Induced by Demineralized Bone Matrix. Annual Meeting of the Orthopaedic Research Society, 2015.

26. Mangano, LM, Gerstenfeld, LC, Morgan, EF. Contrast-enhanced micro-computed tomography of growth plate injury. Annual Meeting of the Orthopaedic Research Society, 2015.œ

27. DelMonaco, AM, Jackman, TM, Fein, PM, Adams, AM, Makhnejia, KK, Morgan, EF. Quantifying the spatial distribution of intradiscal pressure and its assessment via non-invasive estimates of intervertebral disc degeneration. Annual Meeting of the Orthopaedic Research Society, 2015.

28. Jackman, TM, Morgan, EF. QCT-based finite element models do not accurately predict vertebral failure under anterior flexion. Annual Meeting of the Orthopaedic Research Society, 2015.

29. Mangano, LM, Daukss, D, Ravid, K, Gerstenfeld, LC, Morgan, EF. Role of the A2B adenosine receptor in the degradation of bone in rheumatoid arthritis. Annual Meeting of the American Society for Bone and Mineral Research, 2014.

30. Hussein, AI, Morgan, EF. Relationships between the progression of vertebral failure and trabecular architecture in the lumbar spine. 7th World Congress on Biomechanics, 2014.

31. Morgan, EF, Hussein, AI, Unnikrishnan, GU, Jackman, TM. Quantitative visualization of vertebral failure for advancing study of the pathogenesis of spine fractures. 7th World Congress on Biomechanics, 2014.

32. Morgan, EF, Salisbury Palomares, KT, Miller, GJ, Hayward, LNM, Leong, PL. Combining in vivo models, experimental mechanics, and numerical simulation to deconstruct the mechanobiology of bone healing. 7th World Congress on Biomechanics, 2014.

33. Jackman, TM, Hussein, AI, Morgan, EF. Quantitative measurement of the progression of vertebral fracture under anterior flexion. 7th World Congress on Biomechanics, 2014.

34. Hussein, AI, Louzeiro, DT, Unnikrishnan, GU, Barest, GD, Morgan, EF. Accounting for the non-

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uniformity in endplate deflection improves the accuracy of finite-element predictions of vertebral deformation. 60th Annual Meeting of the Orthopaedic Research Society, 2014.

35. Pittman, J, DeGiacomo, A, Cusher, D, deBakker, CMJ, Mroszczyk, KA, Grinstaff, MW, Gerstenfeld, LC, Morgan, EF. Altered Endochondral Ossification during Fracture Healing in Response to BMP Receptor Antagonist. 60th Annual Meeting of the Orthopaedic Research Society, 2014.

36. Miller, GJ, Gerstenfeld, LC, Morgan, EF. Expression of FAK and RhoA in mechanically directed formation of cartilage and bone in vivo. 60th Annual Meeting of the Orthopaedic Research Society, 2014.

37. Bragdon, B, DeGiacomo, A, Aly, S, Hughes, T, Morgan, EF, Gerstenfeld, LC. Bone morphogenetic protein 2 is synergistic in demineralized bone matrix. 60th Annual Meeting of the Orthopaedic Research Society, 2014.

38. Morgan, EF, Bragdon, B, Burns, R, Diviney, P, Baker, A, Belkina, A, Denis, G, Van Wijnen, A, Schlezinger, J, Gerstenfeld, L. Loss of BromoDomain2 function leads to the development of sex-linked osteoporosis. Annual Meeting of the American Society for Bone and Mineral Research, 2013.

39. Bragdon, B, Aly, S, De Giacomo, A, Morgan, EF, Gerstenfeld, L. Demineralized bone matrix concurrently induces vascular tissue formation and endochondral bone formation adjacent to the periosteum. Annual Meeting of the American Society for Bone and Mineral Research, 2013.

40. Bragdon, B, Burns, R, Baker, A, Belkina, A, Denis, G, Morgan, EF, Gerstenfeld, L, Schlezinger, J. Sexual dimorphism of trabecular bone is epigenetically imprinted. Annual Meeting of the American Society for Bone and Mineral Research, 2013.

41. De Giacomo, A, Teich, J, Demay, M, Morgan, EF, Gerstenfeld, L, Einhorn, T. Nutritionally induced delayed union model of femur fractures in mice. Annual Meeting of the American Society for Bone and Mineral Research, 2013.

42. Hussein, AI, Unnikrishnan, GU, Barest, GD, Morgan, EF. Accuracy of QCT-based finite element models of the vertebra. Annual Meeting of the American Society for Bone and Mineral Research, 2013.

43. Morgan, EF, Lelli, A, Miller, GJ, Leong, IP. Correlation between local mechanical stimuli and tissue differentiation in an experimental model of distraction osteogenesis. 59th Annual Meeting of the Orthopaedic Research Society, 2013.

44. Hussein, AI, Roth, S, Demissie, S, Bruno, AG, Allaire, B, Bouxsein, ML, Morgan, EF. Intra-vertebral heterogeneity in bone density is associated with prevalent vertebral fractures in postmenopausal women. 59th Annual Meeting of the Orthopaedic Research Society, 2013.

45. Hussein, AI, Jackman, TM, Morgan, EF. Associations between spatial distributions of bone density with the vertebral centrum and both vertebral strength and disc quality. 59th Annual Meeting of the Orthopaedic Research Society, 2013.

46. Jackman, TM. Hussein, AI, Adams, AM, Makhnejia, KK, Morgan, EF. Endplate deflection is a defining feature of vertebral fracture and is associated with properties of the underlying trabecular bone. 59th Annual Meeting of the Orthopaedic Research Society, 2013.

47. de Bakker, CMJ, Mroszczyk, K, Pittman, J, McDonald, G, Hayward, LNM, Grinstaff, MW, Gerstenfeld, LC, Morgan, EF. Contrast-enhanced computed tomography for quantitative assessment of multiple stages of fracture healing. 59th Annual Meeting of the Orthopaedic Research Society, 2013.

48. Bragdon, B, Burns, R, Baker, AH, Belkina, A, Denis, G, Morgan, EF, Gerstenfeld, LC, Schlezinger, JJ. Sex-linked bone loss and adipocyte differentiation are co-regulated by the brd2 gene. 59th Annual Meeting of the Orthopaedic Research Society, 2013.

49. Hussein, AI, Barest, GD, Morgan, EF. Predictions of vertebral strength using QCT and intra-vertebral heterogeneity in density vs. DXA. Annual Meeting of the American Society for Bone

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and Mineral Research, 2012. Winner of Presidential Poster Competition; 1st Winner of 2012 Summer Travel Poster Award, Force and Motion Foundation

50. Bragdon, B, Burns, R, Baker, AH, Belkina, A, Denis, G, Morgan, EF, Gerstenfeld, LC, Schlezinger, JJ. Role of the brd2 gene in the regulation of sex-linked bone loss and its association with adipocyte differentiation. Annual Meeting of the American Society for Bone and Mineral Research, 2012.

51. Unnikrishnan, GU, Barest, CD, Berry, DB, Hussein, AI, Morgan, EF. Influence of specimen-specific trabecular anisotropy on QCT-based finite element analyses of lumbar vertebra. ASME Summer Bioengineering Conference, 2012.

52. Unnikrishnan, GU and Morgan, EF. A mesh-independent mapping procedure for QCT-based, continuum finite element analyses of vertebrae. International Conference on Structural Stability and Dynamics (ICSSD), 2012.

53. Hussein, AI, Mason, ZD, Morgan, EF. The influence of the intervertebral discs on vertebral mechanics and fracture patterns. 58th Annual Meeting of the Orthopaedic Research Society, 2012.

54. Miller, GJ, Gerstenfeld, LC, Morgan, EF. Correlation of local mechanical environment to induced tissue phenotype. 58th Annual Meeting of the Orthopaedic Research Society, 2012.

55. Hayward, LNM, de Bakker, CMJ, Gerstenfeld, LC, Grinstaff, MW, Morgan, EF. Validation of contrast-enhanced computed tomography for imaging of cartilage in fracture healing. 58th Annual Meeting of the Orthopaedic Research Society, 2012.

56. Hussein, AI and Morgan, EF. Relationships between failure patterns and trabecular architecture in the thoracic spine. Annual Meeting of the American Society for Bone and Mineral Research, 2011. Selected for the Presidential Poster Competition

57. de Bakker, CMJ, Hayward, LNM, Gerstenfeld, LC, Grinstaff, MW, Morgan, EF. Contrast-enhanced computed tomography for non-destructive, quantitative assessment of the early stages of fracture healing. ASME Summer Bioengineering Conference, 2011.

58. Sperry, MM, Hayward, LNM, Miller, GJ, Morgan, EF. Characterization of the poroelastic material properties of skeletal repair tissues using microindentation. ASME Summer Bioengineering Conference, 2011.

59. Miller, GJ, Patel, PG, Morgan, EF. Correlation of local mechanical environment to mechanically induced tissue phenotype during altered bone fracture healing. ASME Summer Bioengineering Conference, 2011.

60. Hussein, AI, Unnikrishnan, G, Morgan, EF. 3-D experimental measurement of vertebral failure: towards validation of QCT-based finite element models. 57th Annual Meeting of the Orthopaedic Research Society, 2011.

61. Hayward, LNM, deBakker, C, Gerstenfeld, LC, Grinstaff, M, Morgan, EF. A cationic CT contrast agent for imaging of soft callus formation in fracture healing. 57th Annual Meeting of the Orthopaedic Research Society, 2011.

62. Leong, PL, Morgan, EF. Experimental measurement of the heterogeneous mechanical environment in distraction osteogenesis. 57th Annual Meeting of the Orthopaedic Research Society, 2011.

63. Gallagher, JA, Morgan, EF. Regional variations in orthotropic elastic properties and the dependence of intra-vertebral heterogeneity on BMD. 57th Annual Meeting of the Orthopaedic Research Society, 2011.

64. Gerstenfeld, LC, Matsubara, H, Hogan, DE, Morgan, EF, Einhorn, TA. Endothelial cells are the primary cells that express BMP2 during distraction osteogenesis. 57th Annual Meeting of the Orthopaedic Research Society, 2011.

65. Bick, T, Kastner, M, Furman, E, Rozen, N, Soudry, M, Morgan, EF, Lewinson, D. Enhancement of fracture repair by local application of VEGF, PTH 1-34, and IL-6. 57th Annual Meeting of the

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Orthopaedic Research Society, 2011. 66. Meeks, BD, Haas, AR, Wigner, NA, Alpaugh, KG, Morgan, EF, Einhorn, TA, Gerstenfeld, LC,

Schlezinger, JJ. The environmental toxicant tributlytin induces osteoporosis via PPARg. 57th Annual Meeting of the Orthopaedic Research Society, 2011.

67. Unnikrishnan, GU and Morgan, EF. Evaluation of the importance of including specimen-specific trabecular anisotropy in QCT-based finite element analyses of the lumbar spine. 19th Annual Symposium of Computational Methods in Orthopaedic Biomechanics, 2011.

68. Morgan, EF, Al-Awadhi, BA, Hogan, DE, Hussein, AI, Al-Alq, Z, Fitch, J, Andre, B, Gerstenfeld, LC. Vascular development during distraction osteogenesis proceeds by the sequence of arteriogenesis exterior to bone followed by angiogenesis within the bone. Annual Meeting of the American Society for Bone and Mineral Research, 2010.

69. Hussein, AI, Morgan, EF, Kim, H. Early effects of femoral head ischemia on bone structure-function relationships and failure patterns. Annual Meeting of the American Society for Bone and Mineral Research, 2010.

70. Grimes, R, Jepsen, KJ, McLean, J, Marsell, R, Fitch, J, Smith, T, Einhorn, TA, Morgan, EF, Sebastiani, P, Gerstenfeld, LC. Identification of coordinated differences in the development of vascular, neurogenic, and skeletal tissues during endochondral bone formation of C57/B6 and C3H strains by comparison of the transcriptomes of fracture healing. Annual Meeting of the American Society for Bone and Mineral Research, 2010.

71. Viguet-Carrin, S, Panus, D, Follet, H, Delmas, PD, Morgan, EF, Chapuriat, R, Bouxsein, ML. Collagen cross-link concentration influences the fatigue behavior of human vertebral trabecular bone. Annual Meeting of the American Society for Bone and Mineral Research, 2010.

72. Leong, PL, Gerstenfeld, LC, Morgan, EF. Spatial expression of chondrogenic genes and chondrocyte morphology in mechanically stimulated pseudoarthroses. 6th World Congress on Biomechanics, 2010.

73. Shore, SW, Morgan, EF, Oberai, AA, Barbone, PE. Anisotropic elasticity imaging of cancellous bone. 6th World Congress on Biomechanics, 2010.

74. Hussein, AI, Morgan, EF. Direct, quantitative visualization of vertebral deformation and failure. 6th World Congress on Biomechanics, 2010.

75. Morgan, EF. Andre, B, Hogan, DE, Al-Awadhi, BA, Gerstenfeld, LC. Quantitative, 3-D imaging to co-localize bone and vascular tissues during bone healing. ASME Summer Bioengineering Conference, 2010.

76. Hussein, AI, Morgan, EF. Direct visualization of the initiation and progression of vertebral fractures. ASME Summer Bioengineering Conference, 2010.

77. Leong, PL, Hayward, LNM, Gerstenfeld, LC, Morgan, EF. Regional expression of cartilage genes in mechanically stimulated pseudoarthroses. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

78. Hussein, AI, Kim, H, Morgan, EF. The effect of femoral head ischemia on bone strength, microstructure and failure patterns. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

79. Young, M, Hsu, F, Mason, ZD, Gerstenfeld, LC, Morgan, EF, Tannoury, T, Einhorn, TA. Effect of cyclic parathyroid hormone 1-31 (cPTH) on spine fusion in ovariectomized (OVX) rats. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

80. Nowlan, N, Jepsen, KJ, Morgan, EF. Smaller, weaker, and less stiff bones evolve from changes in lifestyle. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

81. Miller, GE, Morgan, EF. Use of nanoindentation to determine biphasic material properties of cartilage. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

82. Hayward, LNM, Joshi, N, Gerstenfeld, LC, Grinstaff, M, Morgan, EF. Non-invasive evaluation

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of cartilage in fracture calluses with a cationic CT contrast agent. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

83. Hayward, LNM, Morgan, EF. Evolution of tissue material properties in a mechanically stimulated bone defect. 56th Annual Meeting of the Orthopaedic Research Society, 2010.

84. Altman, K, Vansickle, S, Morgan, EF, Flores, KM. Microscale uniaxial compression testing of bone tissue specimens. TMS Annual Meeting and Exhibition, 2010.

85. Flores, KM, Altman, K, Morgan, EF. Micromachining bone specimens for mechanical testing. NSF CMMI Conference on Engineering Research and Innovation, 2009.

86. Bian, H, Aya-ay, J, Garces, A, Morgan, EF, Gilbert, SR, Kim, H.K. Epiphyseal cartilage plays an important role in revascularization of the femoral head following ischemic osteonecrosis. 2009 Annual Meeting of the Pediatric Orthopaedic Society of North America. Vernon T. Tolo Basic Science Paper Award

87. Hussein, AI, Mason, ZD, Morgan, EF. The effect of intra-vertebral heterogeneity in structure on vertebral strength and failure patterns. 55th Annual Meeting of the Orthopaedic Research Society, 2009.

88. Morgan, EF, Baker, AH, Mason, ZD, Hussein, AI. Quantitative image-guided failure analysis of the human vertebra. 55th Annual Meeting of the Orthopaedic Research Society, 2009.

89. Altman, K, Flores, K, Farson, D, and Morgan, EF. Femtosecond laser micromachining of bone mechanical test specimens. The Minerals, Metals, and Materials Society Annual Meeting and Exhibition, San Francisco, 2009.

90. Morgan, EF, Baker, AH, Mason, ZD, Hussein, AI. Quantitative, three-dimensional visualization of vertebral fractures. World Congress on Osteoporosis, Bangkok, Thailand, 2008.

91. Salisbury Palomares, KT, Gleason, RE, Bellin, D, Miller, GJ, and Morgan, EF. Correlations between local strains and tissue phenotypes in an experimental model of skeletal healing. Gordon Research Conference on Musculoskeletal Biology and Bioengineering, Andover, NH, 2008. Selected for podium presentation

92. Miller, GJ and Morgan, EF. Use of nanoindentation to determine viscoelastic and biphasic material properties of hydrogels and articular cartilage. ASME International Mechanical Engineering Congress and Exhibition (IMECE), Boston, MA, 2008.

93. Mason, ZD, Barbone, PE, Morgan, EF. Experimental measurement of 3-D deformation and failure patterns in the vertebra using digital volume correlation. ASME International Mechanical Engineering Congress and Exhibition (IMECE), Boston, MA, 2008.

94. Hussein, AI, Mason, ZD, Morgan, EF. Predictions of vertebral strength from quantitative measures of the intra-vertebral heterogeneity in density. ASME Summer Bioengineering Conference, 2008.

95. Leong, PL and Morgan, EF. Correlation between nanoindentation modulus and mineral density in fracture callus tissues. ASME Summer Bioengineering Conference, 2008. Honorable Mention, M.S.-level Student Poster Competition, Solid Mechanics Category

96. Hayward, LNM and Morgan, EF. Mechano-regulation of stem cell differentiation during bending stimulation of a healing bone defect. ASME Summer Bioengineering Conference, 2008.

97. Leong, PL and Morgan, EF. Regional variations in fracture callus material properties measured via nanoindentation. Paper #1009, 54th Annual Meeting of the Orthopaedic Research Society, 2008.

98. Salisbury Palomares, KT, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Transcriptional profiling of mechanically induced cartilaginous tissues in vivo. Paper #611, 54th Annual Meeting of the Orthopaedic Research Society, 2008.

99. Salisbury Palomares, KT, Miller, GE, Morgan, EF. Experimental measurement of strains in callus tissues: correlations with mechanically induced tissue phenotypes during skeletal repair.

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Paper #1008, 54th Annual Meeting of the Orthopaedic Research Society, 2008. 100. Gerstenfeld, LC, Sacks, D, Pelis, M, Mason, ZD, Morgan, EF, Einhorn, TA. Comparison of

alendronate versus denosumab (a monoclonal anti-RANKL antibody) on murine fracture healing. Paper #890, 54th Annual Meeting of the Orthopaedic Research Society, 2008.

101. Morgan, EF, Mason, ZD, Bishop, G, Davis, AD, , Gerstenfeld, LC, Einhorn, TA. Combined effects of BMP-7 and PTH in metaphyseal bone healing. Paper #399, 54th Annual Meeting of the Orthopaedic Research Society, 2008.

102. Barnes, GL, Kakar, S, Vora, S, Record, N, Wigner, NA, Morgan, EF, Gerstenfeld, LC, Einhorn, TA. Enhanced chondrogenic maturation in PTH treated fractures. Paper #167, 54th Annual Meeting of the Orthopaedic Research Society, 2008.

103. Alsofi L, Xu, J, Mason, ZD, Morgan, EF, Deguchi, Y, Yamauchi, M, Trackman, PC. Trabecular bone phenotype in lysyl oxidase isoform knockout mice. 37th Annual Meeting of the American Association for Dental Research, 2008.

104. Hunter, DJ, Morgan, EF, Gerstenfeld, LC, Bishop, G, Einhorn, TA, Maciewicz, RA, Newham, P. Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized. World Congress of Osteoarthritis, 2007.

105. Morgan, EF, Oberai, AA, Barbone, PE, Nazarian, A. Anisotropic elasticity imaging with application to elasticity imaging of bone. International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, 2007.

106. Gleason, RE, Palomares, KTS, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. A 3D Histomorphometric method for analyses of skeletal tissue mechanobiology. ASME Summer Bioengineering Conference, 2007.

107. Palomares, KTS, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Hyaline characteristics of mechanically induced cartilaginous tissues. ASME Summer Bioengineering Conference, 2007.

108. Palomares, KTS, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. A novel experimental technique for quantifying the local mechanical environment of skeletal tissues. ASME Summer Bioengineering Conference, 2007.

109. Chien, K, Mason, ZD, Al Sebaei, M, Barnes, GL, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Multivariate assessment of fracture healing via micro-computed tomography. Paper #940, 53rd Annual Meeting of the Orthopaedic Research Society, 2007.

110. Al-Sebaei, MO, Kakar, S, Mason, ZD, Silkman, L, Einhorn, TA, Morgan, EF, Gerstenfeld, LC. Experimental fracture healing in FAS mutant mice (B6.MRL/FASLPR). Paper #356, 53rd Annual Meeting of the Orthopaedic Research Society, 2007.

111. Jacobsen, KA, Alaql, ZS, Cole, RM, Mason, ZD, Morgan, EF, Wan, C, Gilbert, SR, Clemens, TL, Einhorn, TA, Gerstenfeld, LC. Bone formation during distraction osteogenesis is dependent upon both VEGFR1 and VEGFR2 signaling. Paper #180, 53rd Annual Meeting of the Orthopaedic Research Society, 2007.

112. Hadi, N, Price, C, Nasser, P, Morgan, EF, Einhorn, TA, Gerstenfeld, LC, Jepsen, KJ. Genetic variation in the regain of bone strength during fracture healing. Paper #225, 53rd Annual Meeting of the Orthopaedic Research Society, 2007.

113. Cuomo, AV, Virk, M, Petrigliano, F, Morgan, EF, Lieberman, JR. Mesenchymal stem cell concentration and bone repair: potential pitfalls from bench to bedside. Paper #450, 53rd Annual Meeting of the Orthopaedic Research Society, 2007.

114. Fitch, JL, Palomares, KTS, Behnam, K, Knaack, D, Morgan, EF, Einhorn, TA, Gerstenfeld, LC. Comparison of DBM and BMP2 activities in vitro via microarray analysis demonstrates that DBM induces both angiogenesis and skeletagenesis. Annual Meeting of the American Society of Bone and Mineral Research, 2006.

115. Kayal, R, Tsatsas, D, Bauer, M, Krall, E, Morgan, EF, Gerstenfeld, LC, Graves, DT. Diabetes

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may improve fracture healing by excess removal of cartilage. Annual Meeting of the American Society of Bone and Mineral Research, 2006.

116. Barnes, GL, Kakar, S, Jacobsen, KA, Miara, L, Morgan, EF, Gerstenfeld, LC, Einhorn, TA. Parathyroid hormone enhances osteochondroprogenitor proliferation and differentiation during fracture repair through a Wnt signaling mediated mechanism. Annual Meeting of the American Society of Bone and Mineral Research, 2006.

117. Richards, M, Gohkale, N, Liu, L, Morgan, EF, Oberai, AA, Barbone, PE. A method for noninvasive measurement of tissue biomechanical properties. Biomedical Engineering Society Annual Meeting, 2006.

118. Liu, L and Morgan, EF. The accuracy and precision of digital image correlation in quantifying local 3-D strains in trabecular bone depend on trabecular architecture. Fifth World Congress of Biomechanics – joint European Society of Biomechanics track, 2006.

119. Liu, L and Morgan, EF. Accuracy and precision of digital image correlation in quantifying local 3-D displacements and strains in trabecular bone. ASME Summer Bioengineering Conference, 2006.

120. Salisbury, KT, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Mechanobiological regulation of Molecular Expression and Tissue Phenotype. Annual Meeting of the American Society of Bone and Mineral Research, 2005.

121. Salisbury, KT, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Mechanobiological regulation of molecular expression and tissue differentiation during bone healing. ASME Summer Bioengineering Conference, 2005. First place, Masters Level Student Paper Competition, Cell and Tissue Engineering category

122. Salisbury, KT, Einhorn, TA, Gerstenfeld, LC, Morgan, EF. Mechanobiological regulation of cell molecular expression and tissue differentiation in bone healing. Transactions of the 51st meeting of the Orthopaedic Research Society, 2005.

123. Fredericks, EE, Waite, RA, Salisbury, KT, Gerstenfeld, LC, Morgan, EF. Development of a technique to characterize the mechanical properties of articular cartilage in small animal models. Biomedical Engineering Society Annual Meeting, 2004.

124. Morgan, EF, Yeh, OC, Keaveny, TM. Hierarchical investigation of damage in trabecular bone at small strains. Biomedical Engineering Society Annual Meeting, 2004.

125. Morgan, EF, Yeh, OC, Keaveny, TM. Damage in trabecular bone at small strains. European Society of Biomechanics Annual Meeting, Den Bosch, The Netherlands, 2004.

126. Morgan, EF, Longaker, MT, Carter, DR. Spatiotemporal patterns of regenerating tissue mechano-biology in distraction osteogenesis. Transactions of the 50th meeting of the Orthopaedic Research Society, 2004.

127. Morgan, EF, Lee, JJ., Keaveny, TM. Damage in cortical bone in response to a compressive overload. Society for Experimental Mechanics Technical Meeting on the Mechanics of Biological and Biologically Inspired Materials and Systems, Springfield, Massachussetts, 2003.

128. Morgan, EF, Loboa, EG, Fang, TD, Longaker, MT, Carter DR. Temporal variations in mechanical stimuli during mandibular distraction osteogenesis. 10th International Congress of the International Society of Craniofacial Surgery, Monterey, California, 2003.

129. Morgan, EF, Bayraktar, HH, Yeh, OC, Keaveny, TM. Contribution of inter-site differences in architecture to trabecular bone yield behavior. Transactions of 48th meeting of the Orthopaedic Research Society, p. 90, 2002.

130. Bayraktar, HH, Niebur, GL, Morgan, EF, Keaveny, TM. Elastic and failure properties of trabecular tissue at the human femoral neck. ASME Summer Bioengineering Conference, Salt Lake City, Utah, 2001.

131. Morgan, EF, Yeh, OC, Keaveny, TM. Nonlinear behavior of trabecular bone at small strains.

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Transactions of 46th meeting of the Orthopaedic Research Society, p. 31, 2000. 132. Morgan, EF, Arramon, YP, Kopperdahl, DL, Keaveny, TM. Dependence of yield strain on

anatomic site for human trabecular bone. ASME IMECE, BED Vol 43: 23-24, 1999. First place, Bioengineering Division Master’s Level Student Paper Competition

133. Arramon, YP, Yeh, OC, Morgan, EF, Keaveny, TM. Axial-shear failure behavior of human femoral trabecular bone. ASME IMECE, BED Vol 43: 173-174, 1999.

134. Keaveny, TM, Yeh, OC, Morgan, EF, Chang, WC, Haddock SM. Non-linear elastic behavior of trabecular bone. Third World Congress of Biomechanics, Sapporo, Japan, p. 260, 1998.

Invited Technical Seminars and Lectures 1. Invited Talk, William F. Neuman Visiting Scientist Speaker Series, University of Rochester

Medical Center, October 2018. 2. Keynote Talk, Summer Course on Image-based Biomedical Modeling, Park City, Utah,July 2018 3. Invited Talk, 11th Annual Suzanne Bernier Memorial Lecture in Skeletal Biology, University of

Western Ontario, Canada, May 2018. 4. Invited Talk, Squishy Physics & Pizza Seminar, Harvard University, December 2017 5. Department Seminar, Department of Mechanical Engineering, University of Texas San Antonio,

November 2017. 6. Invited Talk, Pre-meeting Symposium “Current Concepts in Bone Fragility: From Cells to

Surrogates”, Annual Meeting of the American Society for Bone and Mineral Research, September 2017.

7. Invited Talk, Session on “Research Highlights”, Annual Meeting of the Orthopaedic Research Society, 2017.

8. Invited Talk, 2nd Musculoskeletal Development and Regeneration Conference, Cancun, Mexico 9. Invited Talk, Molecular Biology of Bones and Teeth Section, National Institute of Dental and

Craniofacial Research, National Institutes of Health, April 2016. 10. Invited Talk, 4th Annual Symposium on Musculoskeletal Repair and Regeneration, Einstein

College of Medicine, October 2015. 11. Spotlight Talk (invited), “Image assessments of the biomechanics and biology of bone healing”,

Annual Meeting of the Orthopaedic Research Society, Las Vegas, March 2015. 12. Invited Talk, BMES Cell and Molecular Bioengineering meeting, St. Thomas, USVI, January

2015. 13. Department Seminar, Orthopaedic Surgery, Massachusetts General Hospital, December 2014. 14. Invited Talk, Osteosynthesis and Trauma Care (OTC) Foundation Workshop on “Osteoporosis

and Bone Strength—The Mechanical Perspective”, November 2014. 15. Department Seminar, Mechanical Engineering, University of Delaware, November 2014 16. Invited Talk, World Congress of Biomechanics, July 2014 17. Invited Talk, International Workshop on Multiscale Mechanobiology, Hong Kong, May 2014 18. Department Seminar, Biomedical Engineering, Washington University, October 2013 19. Department Seminar, Biomedical Engineering, SUNY Stonybrook, September 2013 20. Invited Lecture, American Academy of Orthopaedic Surgeons (AAOS) Research Symposium,

Bone Quality and Fracture Prevention, Rosemont, IL, May 2013. 21. Invited Talk, American Association of Anatomy, Symposium on “Novel 3D Imaging with Micro-

Computed Tomography”, Boston, MA, April 2013. 22. Invited Talk, Society for Injectable Osteoarticular Biomaterials (GRIBOI), Boston, MA, April

2013 23. Invited Talk, Osteosynthesis and Trauma Care (OTC) Foundation Workshop on “Functional

Assessment of Fracture Healing”, December 2012. 24. Seminar, Forsyth Institute, December 2012.

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11/21/18 CV – EF Morgan, p.17

25. Department Seminar, Biomedical Engineering, Tufts University, March 2012. 26. Seminar, Trinity Centre for Bioengineering, Trinity College Dublin, Ireland, January 2012. 27. Invited Talk, Sun Valley Workshop on Musculoskeletal Biology, Session on “Fracture Healing

and Non-Union”, August 2011. 28. Invited Talk, Biomethods Boston Conference, Session on “Methods and Advances in

Mechanobiology”, July 2011. 29. Invited Talk, Symposium on “Full-field measurement and identification in solid mechanics”,

International Union of Theoretical and Applied Mechanics (IUTAM), Cachan, France, July 2011. 30. Department Seminar, Faculty of Medicine Lyon-Est, University of Lyon, France, July 2011. 31. Department Seminar, Mechanical and Aerospace Engineering, University of California San

Diego, May 2011. 32. Invited Talk, Boston Older Adults Independence Claude D. Pepper Center, Boston Medical

Center, March 2011. 33. Department Seminar, Orthopaedic Surgery, University of California San Diego, February 2011. 34. Interdepartmental Seminar, Rheumatology, Allergy, and Immunology Seminar Series (RAISS),

University of California San Diego, January 2011. 35. Department Seminar, Mechanical Engineering, University of California Berkeley, October 2010. 36. Department Seminar, Bioengineering, University of California San Diego, October 2010. 37. Department Seminar, Mechanical, Aerospace, and Nuclear Engineering, Rensselaer Polytechnic

Institute, November 2009. 38. Department Seminar, Bioengineering, University of Utah, February 2009. 39. Invited Talk, Symposium on “Biomaterials: properties, variation and evolution”, Annual

Meeting of the Society for Integrative and Comparative Biology, Boston, January 2009. 40. Invited Talk, World Congress on Osteoporosis, Bangkok, Thailand, December 2008. (conference

cancelled) 41. Department Seminar, Bioengineering, University of Pennsylvania, November 2008. 42. Department Seminar, Bioengineering, University of Maryland, October 2008. 43. Invited Lecture, Orthopaedic Trauma Association Basic Science Fracture Forum, Denver, CO,

October 2008. 44. Department Seminar, Materials Science and Engineering, Massachusetts Institute of Technology,

February 2008. 45. Department Seminar, Mechanical and Aerospace Engineering, Cornell University, February

2008. 46. Department Seminar, Biomedical Engineering, Columbia University, February 2008. 47. Department Colloquium, Departments of Orthopaedic Surgery and Cell Biology, University of

Massachusetts Medical School, October 2007. 48. Seminar, Center for Biomolecular and Tissue Engineering, Duke University, October 2007. 49. Department Seminar, Mechanical and Aerospace Engineering, Case Western Reserve University,

September 2007. 50. Invited Lecture, American Academy of Orthopaedic Surgeons (AAOS) Research Symposium,

Fracture Repair: Challenges and Opportunities, Miami Beach, FL, April 2007. 51. Invited Lecture, Ortoreuma 2005: International Conference on Bone and Joint Aging, Milan,

Italy, September 2005. 52. Department Colloquium, Department of Orthopaedic Surgery, Brown University, February 2005. 53. Department Seminar, Department of Mechanical Engineering, Northeastern University, January

2005. 54. Department Seminar, Department of Aerospace & Mechanical Engineering, University of Notre

Dame, October 2004. 55. Orthopedic Biomechanics Laboratory Seminar, Department of Orthopedic Surgery, Harvard

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11/21/18 CV – EF Morgan, p.18

University, June 2004. 56. Department Seminar, Department of Mechanical Engineering, University of Rhode Island, April

2004.

Professional Societies and Service Journal of Biomechanics Associate Editor 2015- American Society of Mechanical Engineers

Theme Leader (Theme: Hard Tissue and Joints) for the 2008 and 2009 ASME Summer Bioengineering Conferences

Reviewer of submitted abstracts, 2007-2009,2011,2012, 2013, 2016 meetings Orthopaedic Research Society

Member at Large, Board of Directors, 2016-2018 (elected position) Nominating Committee for 2015 and 2019 annual meetings (invited position) Topic Chair (“Bone Fracture”) for 2014 and 2015 meetings (invited position) Session moderator for 2011, 2012, 2013, 2017 meetings Reviewer of submitted abstracts, 2009, 2011-13, 2016-18 meetings

American Society for Bone and Mineral Research Reviewer of submitted abstracts, 2014, 2016 meetings

Reviewer for various journals: Nature Materials, Scientific Reports, Journal of Biomechanics, Journal of Bone and Mineral Research, Spine, Bone, Journal of Biomechanical Engineering, Experimental Mechanics, Annals of Biomedical Engineering, Journal of Orthopaedic Research, Journal of Biomedical Materials Research, Biomechanics and Modeling in Mechanobiology, Osteoporosis International, Journal of Bone and Joint Surgery, Materials Research Communications, European Journal of Morphology, Chaos, Journal of Dental Research, Clinical Orthopaedics and Related Research, Journal of Experimental Biology, Computer Methods in Biomechanics and Biomedical Engineering, Sensors, PLOS One, Journal of Theoretical Biology

2016-2018 Chairperson, Musculoskeletal, Oral and Skin Sciences IRG, NIH (3 study sections/year) five years NSF review panel 2014 Session Organizer and Chair, Tissue Mechanics track and Organ track, 2014 World

Congress of Biomechanics 2014-2016 Standing Member, Musculoskeletal, Oral and Skin Sciences IRG, NIH (3 study

sections/year) 2012 Review Panel, Canadian Institutes of Health Research 2010 Session Chair/Organizer, Bone Healing and Fracture Repair, 6th World Congress of

Biomechanics 2009 Special Emphasis Review Panel, Musculoskeletal, Oral and Skin Sciences IRG, NIH 2007 Special Emphasis Review Panel, “Enabling Technologies for Tissue Engineering and

Regenerative Medicine”, NIH-NHLBI 2006, 2011 Moderator, Annual Symposium of Computational Methods in Orthopaedic Biomechanics 2005 Special Emphasis Review Panel, Shared Instrumentation Grant Program (Imaging), NIH-

NCRR 2004 Reviewer, US-Israel Binational Science Foundation 2004 Reviewer, Scottish Hospital Endowment Research Trust 2003 Moderator, 12th Annual Symposium of Computational Methods in Orthopaedic

Biomechanics

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Extramural Research Funding Active 2017-22 NIH-NIAMS R01, PI (3 PIs total), “A Systems Genetics Approach to Identify BMD

Genes”, $2,249,992 (total costs) 2017-18 Arthritis Foundation, co-PI, “The Mechanistic Role of Subchondral Bone Cysts and

Bone Marrow Lesions as Markers of Cases for Arthroplasty”, $50,000 (PI: Eric Smith) (total costs)

2014-19 NIH-NIAMS R01, PI, “3-D Visualization and Prediction of Spine Fractures”, $1,841,064 (total costs)

2013-18 NIH-NIAMS, Investigator, “Biomechanics of Vertebral Fracture: The Framingham QCT Study” (PI: ML Bouxsein), $2,567,082 (total costs) no-cost extension

Completed 2013-17 NSF-CMMI, PI, “Tracking Cell Fate during Mechanically Directed Bone Regeneration

In Vivo”, $280,130 (total costs) 2012-16 NIH-NIAMS, Investigator, “A Systems Genetic Approach to Fracture Healing” (PI: LC

Gerstenfeld), $1,841,624 (total costs) 2011-16 NIH-NIAMS, Investigator, “The Role of Angiogenesis in Distraction Osteogenesis”

(PI: LC Gerstenfeld), $2,028,687 (total costs) 2014-15 NSF-CBET, PI, “MRI: Acquisition of A Dual-Energy, 3-D X-Ray Microscope With

Sub-Micron Resolution, Tunable Field Of View, and Phase Contrast”, $419,000 (total costs)

2013-15 Osteosynthesis and Trauma Care Foundation, PI, “Contrast-Enhanced Computed Tomography and Radiography for Early and Rapid Identification of Healing Prognosis”, $50,000 (total costs)

2013-14 NIH-NIAMS R56, PI, “3-D Visualization and Prediction of Spine Fractures”, $364,238 (total costs)

2008-13 NIH-NIAMS R01, PI, “3-D Visualization and Prediction of Spine Fractures”, $1,607,356 (total costs)

2011-12 Smith and Nephew, PI, “Micro-Computed Tomography Assessment of TRUFIT”, $48,762 (total costs)

2011-12 Acceleron, Inc., Investigator, “Comparison of a Soluble TGF-beta Receptor Family Protein on Murine Fracture Healing” (PI: LC Gerstenfeld), $65,645.23 (total costs)

2011-12 Musculoskeletal Transplant Foundation, Investigator, “Role of Angiogenesis in Bone Repair” (PI: LC Gerstenfeld), $300,000 (total costs)

2010-11 NIH-NIAMS F33, PI, “Mechanical Consequences of Focal Articular Defects”, $59,918 (total costs)

2008-11 NSF/CMMI, PI, “Collaborative Research: Micro- and Nano-Scale Characterization and Modeling of Bone Tissue”, $67,940 (total costs)

2009-10 NIH-NIAMS R01 administrative supplement, PI, “Inducing Skeletal Repair by Mechanical Stimulation”, $64,152 (total costs)

2005-09 NIH-NIAMS R01, PI, “Inducing Skeletal Repair by Mechanical Stimulation”, $1,156,200 (total costs)

2004-09 NIH P01, Core Co-Investigator, “Molecular Mechanisms of Skeletal Repair” (PI: TA Einhorn), $5,529,749 (total costs)

2007-09 Shriners Hospitals for Children (prime), subcontract PI, “Prevention of Femoral Head Deformation following Ischemic Osteonecrosis”, $22,748 (total costs)

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2007-08 Zelos, Co-Investigator, “Comparison of Ostabolin-C to Parathyroid Hormone (1-34) in the Enhancement of Experimental Fracture Healing”, (PI: TA Einhorn), $118,290 (total costs)

2007 Harvest, Co-Investigator, “Therapeutic Potential of Human Marrow Stromal Cells to Enhance Critical Size Defect Healing”, (PI: TA Einhorn), $88,213 (total costs)

2006-07 Amgen, Co-Investigator, “Comparison of Two Anti-Resorptive Therapies (Alendronate versus AMG 162 Monoclonal Anti-RANKL Antibody) on Murine Fracture Healing”, (PI: TA Einhorn), $36,722 (total costs)

2006-08 International Osteoporosis Foundation, PI, “3-D Visualization and Prediction of Spine Fractures”, €40,000 (total costs)

2005-07 NSF-BES, PI, “Acquisition of a High-Resolution Micro-Computed Tomography System with Large Sample Capacity”, $269,000 (total costs)

2006-07 GlaxoSmithKline, Co-Investigator, “Comparison of SB 768974 and SB 751689 to Parathyroid Hormone (1-34) in the Enhancement of Experimental Fracture Healing”, (PI: TA Einhorn), $162,407 (total costs)

2006 Stryker Pharmaceuticals, Co-Investigator, “Synergism between OP-1 and PTH in a Rabbit Model of Tibial Healing” (PI: TA Einhorn), $170,104 (total costs)

2005-06 NIH-NCRR, PI, “High-Resolution Desktop Micro-Computed Tomography System”, $210,000 (total costs)

2005-06 BioSET, Inc., Co-Investigator, “Therapeutic Potential of B2A2 in Enhancement of Normal Fracture Repair” (PI: TA Einhorn), $17,551 (total costs)

2004-05 Stryker Pharmaceuticals, Co-Investigator, “Pilot Study to Assess Synergism between PTH and BMP-7 in a Rabbit Model of Tibial Healing” (PI: TA Einhorn), $27,242 (total costs)

2004-05 Biomimetics, Inc., Co-Investigator, “Enhancement of Experimental Fracture Healing with PDGF” (PI: TA Einhorn), $55,011 (total costs)

Other Funding 2018-20 Hariri Institute Research Incubation Award, co-PI, “Data-Driven Design of Tough 3D-

Printed Structures”, $50,494 (total costs) 2017-18 Dean’s Catalyst Award, co-PI, “Autonomously Engineering Tough Hierarchical

Materials”, $82,000 (total costs) 2017-18 CTSI, PI, “The Mechanistic Role of Subchondral Bone Cysts in Hip Osteoarthritis”,

$20,000 (total costs) 2011 Mary Erskine Award, PI, “Control of Cell and Tissue Fate through Mechanical

Stimulation of Skeletal Healing”, $20,000 (total costs) 2009-10 Dean’s Catalyst Award, co-PI, “Shock Wave Therapy for Treating Non-Union Bone

Fracture”, $29,434 (total costs) 2004 Boston University Office of the Provost, Special Program for Research Initiation

Grants (SPRInG), PI, “Mechanobiology of Osteoblast-Endothelial Cell Interactions”, $25,000 (total costs)

Courses Taught Undergraduate EK301, “Engineering Mechanics I” ME305, “Mechanics of Materials”

Graduate ME524, “Skeletal Tissue Mechanics”

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ME582, “Mechanical Behavior of Materials” Orthopaedic Surgical Residents’ Basic Science Lecture Series (1 lecture/year) GMS MM730, “Biological Core Technologies” (1 lecture/semester)

Mentoring and Outreach Activities Mentoring and Professional Development 2016, 2018 Speaker, New Investigator Workshop, Orthopaedic Research Society, Orthopaedic

Research and Education Foundation, American Academy of Orthopaedic Surgeons 2018- Advisory Board, ARROWS (Advance, Recruit, Retain & Organize Women in STEM),

Boston University 2018 Panelist, Workshop on preparing a faculty job application, Office of Postdoctoral

Affairs, Boston University 2017 Speaker and Panelist, Workshop on preparing NIH biosketches, Annual Meeting of the

Orthopaedic Research Society, San Diego, CA 2016 Speaker, Workshop “Communicating Science”, SB3C Conference, National Harbor,

MD 2015- Member or chair of 1-2 mentoring committees for tenure-track faculty in the

Department of Mechanical Engineering at Boston University 2015 Panelist, Workshop on academic careers, GWISE, Boston University 2014 Panelist, Workshop on preparing for faculty job interviews, GWISE, Boston

University

K-12 Outreach 2007- Co-Founder and Co-Organizer, Summer Pathways

(https://www.bu.edu/lernet/spathways/index.html), Boston University 2006-07 Faculty Participant, Learning Experiences for New Scientists, Boston University 2005 Faculty Participant, AME Day, Boston University 2005 Faculty Participant, AME Science Day, Boston University 2005 Judge, Science and Engineering Day, Boston University 2004 Judge, Peak Performance Engineering Design Competition, Boston University

University Service University 2018- Advisory Board, Interdisciplinary Biomedical Research Office one year Selection Committee, University Commencement Student Speaker 2016-17 General Education Implementation Task Force one year Selection Committee, Howard Hughes Medical Institute 2006-2011 Steering Committee, WISE@Warren Residential Community College of Engineering one year Selection Committee, Dean’s Catalyst Awards three years Appointments, Promotion, and Tenure Committee two years Selection Committee, Award for Early Career Research Excellence one year Selection Committee, DeLisi Award 2009 Dean’s Research Advisory Council 2006-07 Dean’s Search Faculty Panel 2006-07 Advanced Materials Cluster Committee Department

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2018-19 Member, Strategic Planning Committee 2015-18 Associate Chair for Graduate Research Programs 2012-14 co-Associate Chair for Graduate Affairs 2012-13 Member, Chair Search Committee 2011-12 Chair, Seminar Committee 2005-06, Member, Search Committee

2011-12, 2013-14, 2015-16 2018-19

2010 Chair, Website Committee 2006 Member, Chair Search Committee 2003-12*, Member, Graduate Committee

2014-15 2003-12* Member, Solids and Structures Committee *sabbatical in 2010-11 and maternity leaves in 2008 and 2010 excepted

Advisees and Staff Primary Advisor – Graduate Level 2021 (anticipated)

Joshua Auger Ph.D., ME Boston University

2020 (anticipated)

Yunqiao Wu Ph.D., ME Boston University

2020 (anticipated)

JohnFredy Loaiza Ph.D., ME Boston University

2019 (anticipated)

Jenny Lei

Ph.D., ME Boston University

2016 Paul Fein “Associations between the spatial distribution of bone density in the vertebra and intervertebral disc health”

First placement: Associate Product Engineer, Arthrex

M.S., ME Boston University

2016 Alexander del Monaco “Quantifying the spatial distribution of intradiscal pressure and its assessment via non-invasive estimates of intervertebral disc degeneration”

First placement: Associate Product Engineer, Arthrex

MS, ME, Boston University

2016 Young Guang “Characterization of bone and bone marrow lesions in the osteoarthritic hip”

First placement: Ph.D. program in BME, Washington University in St. Louis

MS, ME, Boston University

2016

Lauren Mangano “Non-destructive assessment of cartilaginous tissues in small animal models of injury and disease”

First placement: Assistant Licensing Manager, Office of Research Commercialization, Rutgers University

Ph.D., BME Boston University

2015

Timothy Jackman “Prediction of vertebral fractures under axial compression

Ph.D., BME Boston University

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and anterior flexion using non-invasive assessments of intervertebral disc health”

First placement: The Mathworks, Inc. 2012

Alessandra Lelli “Analisi della stimolazione meccanica nella guarigione di una frattura” (“Analysis of mechanical stimulation in the healing of a fracture”)

First placement: Project Engineer, NEST Consulting

M.S., Bioengineering University of Florence

2012 Charlotte Naylor “Radiolucent device to apply compression and flexion for the study of vertebral failure mechanisms”

First placement: Systems Integration Analyst, Accenture

M.S., BME Boston University

2011

Spencer Shore “Transversely isotropic elasticity imaging of cancellous bone: feasibility and uniqueness of solutions” First placement: Design Engineer, Orchid Design

M.S., ME Boston University

2013

Amira Hussein “3-D visualization and prediction of spine fractures under axial loading”

First placement: Postdoctoral Fellow, Orthopaedic Surgery, Boston University School of Medicine (Louis Gerstenfeld, supervisor)

Ph.D., ME Boston University

2013

Greg Miller “Mechanoregulation and mechanotransduction in skeletal tissue differentiation”

First placement: Postdoctoral Fellow, Royal College of Surgeons, Dublin, Ireland (Fergal O’Brien, supervisor)

Ph.D., ME Boston University

2012 Lauren Hayward “Investigations into the quantitative relationship between the mechanical environment and skeletal healing”

First placement: Postdoctoral Fellow, BME, Tufts University (David Kaplan, supervisor)

Ph.D., BME Boston University

2010

John Gallagher “Intra-vertebral heterogeneity in orthotropic elastic properties”

First placement: Ph.D. program in Mechanical Engineering, UCLA

M.S., ME Boston University

2010 Pui Leong “Spatial localization of mechanical cues and cellular Responses during Bone Healing In Vivo”

First placement: Postdoctoral Fellow in Bone Bioengineering Laboratory (X. Edward Guo, director) at Columbia University

Ph.D., BME Boston University

2007 Kristy Salisbury Palomares “Mechanobiological regulation of cell and molecular expression during tissue differentiation in bone healing”

First placement: Residency program in Medicine, Robert Wood Johnson University Medical Group

Ph.D., BME Boston University

2006 Nicholas Pratt First placement: Analytical Engineer II, Vermont Composites

M.S., ME Boston University

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2005 Li Liu “Measurement of in situ strains in trabecular bone”

First placement: Dosimetrist, Mass. General Hospital

Ph.D. prospectus, AME Boston University

Primary Advisor – Undergraduate Level Name Supporting Program First Placement / (Current Position) 2018- Amartya Naik Presidential Scholars (Sophomore, BME) 2018- Kaitlyn Shreeve (Sophomore, BME) 2018- Kaya Alvillar Adelzadeh Presidential Scholars (Junior, BME) 2018- Olivia Blouin (Senior, BME) 2018- Rohin Banerji (Senior, BME) 2018 Leslie Flores UROP (Junior, ME) 2017- MeiLissa McKay UROP (Junior, BME) 2017- Rachel Wilhelm UROP (Senior, ME) 2017 Keqin Ding Smith College PhD program, Boston University 2016-17 Jaclyn Grode Engineering Intern, Bioventus 2016-17 Kathryn Hardin Clinical Research Coordinator 2016-17 Lindsay Hulley MS, BME, Duke University 2016-17 Caeleigh Higgins 2016 Cianael Passewe NSF REU 2016- Ryan Shimazu UROP, Lutchen Fellowship (Senior, BME) 2015-16 Cheryl Lu 2015-16 Willie Mermell 2015- Claire Rodman Lutchen Fellowship, UROP PhD program, BME, Penn State 2015- Eric Rapp Lutchen Fellowship, UROP PhD program, ME, CMU 2015- Meghan Kupratis UROP PhD program, BME, U. Delaware 2015- Blake Oberfeld Presidential Scholars, UROP Clinical Research Coordinator 2015 Cierra Searcy (Senior, Biology) 2015- Cameron Curtiss Research Technician, KU Leuven 2014-15 Jordan Desautels Post-Baccalaureate program 2014-15 Amanda Grafilo Medical Scribe, Children’s

Specialized Hospital 2014-15 Brittany Pack 2013-15 Kathryn Gikas NSF Analyst, Accenture 2014-16 Katie Li Research Assistant, Alnylam

Pharmaceuticals 2014-15 Kamolnat Tabattanon MS program, Oregon State 2013-14 Alexander DelMonaco MS program, ME, Boston

University/(Associate Product Engineer, Arthrex)

2013-14 Laura Windmuller Analyst, Accenture 2013-14 Mitalee Desai Engineer, GoPro 2013-15 Young Guang Lutchen Fellowship M.S. program, ME, Boston

University/(Ph.D. program, BME, WashU)

2012 Christopher Greco US Navy 2012-14 Daniel Louzeiro Research Analyst, Technology

Solutions Experts, Inc

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2012 Sharon Roth Senior, BioE, University of Pennsylvania

2012-14 Alexander Adams Process Engineer, Boston Scientific

2012 Krutika Hosur 2011-14 Benjamin Pritz Engineering Scholars M.D. program, University of

Pittsburgh 2011-12 Daniel Grasso Ph.D. program, BME, Boston

University 2011-14 Kamil Makhnejia MEng program in Biomedical

Innovation and Development, Georgia Tech

2011 Stacyann Morgan SURF PhD, Biomedical Engineering, RPI

2010-11 Parth Patel 2010-12 Chantal De Bakker Lutchen Fellowship, UROP Ph.D. program, BioE, University

of Pennsylvania; Recipient of NSF Graduate Research Fellowship

2009-12 Keri Mroszczyk UROP M.S. program, ME, MIT/(Lincoln Laboratory)

2009-12 David Berry UROP, Lutchen Fellowship Ph.D. program, BioE, UCSD 2009-12 Megan Sperry UROP M.Phil. program, BioE, Imperial

College London; Recipient of Pre-Doctoral Fellowship from the Whitaker International Program

2009 Jasmine Jackson SURF Senior, BME, Columbia University

2009-10 Alyssa Trigger M.S. program, Engineering Management, Duke University

2007-09 Daniel Bellin NSF-REU, UROP Ph.D. program, EE, Columbia University; Recipient of DoD-NDSEG Graduate Fellowship

2007-08 Anthony Pfeiffer M.D. program, University of Pittsburgh

2007 Mohit Butaney 2007-10 Alexina Fredman UROP Project Manager, Epic Systems

Corporation 2006-09 Karen Chien UROP Recipient of NSF Graduate

Research Fellowship; Ph.D. program, Northwestern University

2006-07 Andrew Baker NSF-REU, Senior Project Test Engineer, DFine, Inc.; DPT program, University of Pittsburgh

2006-08 Ryan Gleason Industrial Research Fellowship

Product Development Engineer, Atrium Medical

2005 Jennifer Treese 2004-06 Jared Bancroft UROP, NSF-REU Manager of Business Systems &

Applications, BU-ENG 2004-05 Akihiro Hidaka 2004 Erin Fredericks NSF-REU

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2004 Ryan Waite NSF-REU Ph.D. program, Georgia Tech 2003-04 Shannon Rowell Research Technologist, Harris

Orthopaedic Biomechanics and Biomaterials Lab, MGH

2003-04 David Litvak

Primary Advisor – High School Students 2014 Anderson Camp, Gunston High School, Centerville, Maryland (supported by the BU

Research Internship in Science and Engineering (RISE) program) 2010 Angelina Chaney, Ridgeway High School, Ridgeway, Colorado

(supported by the Pinhead Institute: http://www.pinheadinstitute.org/k12_internship.htm http://pinheadinterns2010.ning.com/profile/AngelinaChaney?xg_source=activity)

2009 Ilana Usiskin, The Lawrenceville School, Mendham, New Jersey (supported by the BU Research Internship in Science and Engineering (RISE) program)

Supervisor – Postdoctoral Fellows 2016-18 Jarred Kaiser

First Placement: Research Scientist, Department of Orthopaedic Surgery, Emory University

2009-12 Ginu U. Unnikrishnan First Placement: Research Scientist II, Department of Defense Biotechnology HPC Software Applications Institute

2009 Niamh C. Nowlan First Placement: Lecturer, Department of Bioengineering, Imperial College London

Supervisor – Staff 2018- Aaron Nakasone, Research Technician 2016-18 Jingjiang Liu, Research Technician

First Placement: Technology Architecture Analyst, Accenture 2013-14 Rachel Danzig, Research Assistant

First Placement: MD program, Rush Medical College 2013-16 Michael Zachary Webster, Research Technician

First Placement: Technology Analyst, Accenture 2011-13 Gabriel McDonald, Research Technician

First Placement: Abrasives Engineer, Saint-Gobain Corporation 2010-11 Daniel Hogan, Research Technician

First Placement: Student, A.T. Still University School of Osteopathic Medicine 2009-10 Billy Andre, Research Technician 2005-08 Zachary Mason, Research Technician

First Placement: Assistant Director of Engineering, Human Engineering Research Laboratories, VA Pittsburgh Healthcare System

Committee Member – Graduate Level 2017 Xunjie Yu

“Micromechanics of elastic lamina” Ph.D. prospectus

ME Boston University

2017 Haiyue Li “Multiscale mechanics of collagen extracellular matrix”

Ph.D. prospectus

ME Boston University

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2017 Jeff Mattson “Contribution of collagen, elastin, and proteoglycans to aorta mechanics”

Ph.D.

ME Boston University

2016 Hannah Peterson “Diffuse Optical Spectroscopic Imaging as a Prognostic Tool for Sarcoma”

Ph.D. prospectus

BME Boston University

2016 Ali Mohammed “Development and application of optogenetics platform for controlling and imaging large numbers of individual neurons”

Ph.D. ME Boston University

2016 Yunjie Wang “Arterial mechanics considering the structural, mechanical, and biochemical contents of elastin”

Ph.D. ME Boston University

2015 Alexander Bruno “Vertebral Fracture Biomechanics”

Ph.D. MEMP Harvard-MIT

2014 Rachel Stewart “Cationic contrast agents for imaging articular cartilage with computed tomography”

Ph.D.

BME Boston University

2013

Jeffrey Brown “Exploring the developing tenocyte phenotype in order to enhance a developmental approach to engineering tendon”

Ph.D. BME Tufts University

2012 Peter Chang “High-speed atomic force microscopy through local raster scanning”

Ph.D. ME Boston University

2012 Hanifeh Khayyeri “Computational investigation of the sources of variability in mechanobiological regulation of tissue differentiation during bone healing”

Ph.D. Bioengineering Trinity College Dublin (external examiner for Viva Voce)

2012 Rafael Yao “The effects of mechanical stimulation on controlling and maintaining marrow stromal cell differentiation into vascular smooth muscle cells”

Ph.D. BME Boston University

2011 Sean Serell “Influence of alterations in bone tissue properties on whole bone strength”

M.S. BME Boston University

2011 Prashant Bansal “Contrast-enhanced computed tomographic imaging of articular cartilage: interrelationships with biochemical and biomechanical properties”

Ph.D. BME Boston University

2010 Yu Zou “Biomechanical study of the elastic and viscoelastic behavior of the extracellular matrix”

Ph.D. ME Boston University

2009 Holly Brideau “The inter-relationship between mr diffusion measures and the mechanical status of the intervertebral disc”

M.S. ME Boston University

2008 Alvin Khan “Cetacean hearing and the impact of naval sonar”

Ph.D. BME Boston University

2008 Nate Wigner “Transcriptional regulation of aggrecan: mechanisms of chondrocyte differentiation”

Ph.D. Biochemistry Boston University

2008 Jessica Kaufman “Mechanical characterization of stiffness gradient

Ph.D. BME Boston University

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hydrogel substrates for tissue engineering” 2009 Andy Golden

“Fabrication of functional blood vessel networks” Ph.D. BME

Boston University 2009 Carlos Rivas

“Analysis of finite element formulations for solving inverse problems treated as optimization problems”

Ph.D. AME Boston University

2007 Eben Tessari “Gradient microenvironments for neural regenerative materials”

M.S. BME Boston University

2007 Kristen La Flamme “Nanoporous alumina interfaces for cellular encapsulation and controlled drug delivery”

Ph.D. BME Boston University

2007 Erica Thrall “Predicting strength in the human proximal femur”

M.S. BME Boston University

2006 Nachiket Gokhalen “Inverse problems in non-linear elasticity imaging”

Ph.D. AME Boston University

2009 Harikrishnan Parameswaran “Relating microscopic and macroscopic indices of alveolar structure: applications for emphysema”

Ph.D. BME Boston University

2006 Haibao Luo “Three-dimensional model of elastic wave propagation in kidney stones with application to shock wave lithotripsy”

Ph.D. AME Boston University

2006 Oluwaseyi Balogun “Materials characterization using frequency domain photoacoustic microscopy”

Ph.D. AME Boston University

2006 Elissa Beekman “Fabrication and evaluation of nanostructured titania for osteoblast cell culture”

M.S. BME Boston University

2005 Jeffrey Jacot “Multiscale analysis of arterial bypass remodeling”

Ph.D. BME Boston University

2005 David Michael Foster “Microgrooves dominate cyclic strain response of vascular smooth muscle cell orientation”

M.S. BME Boston University

2005 Thomas Steen “Laser ultrasonic inspection of subsurface defects in flip-chips”

M.S. AME Boston University

2005 John Jagodnik “Finite element method applied to bone growth and tissue differentiation with application to dental implants”

Ph.D. prospectus

ME Northeastern Univ.

2005 Matthew Heverly “Minimizing tissue motion during needle insertion”

M.S. AME Boston University

2004 Erin Leary Swann “Fabrication and evaluation of uniformly sized nanoporous alumina for human osteoblast cell culture”

M.S. BME Boston University