Effects of Ayurvedic treatment on forty-three patients of ulcerative colitisManish V. Patel,1 Kalapi B. Patel,2 and S. N. Gupta3Author information op!ri"ht and #i$ense information %his arti$le has &een $ited &! other arti$les in PM.Abstract'l$erati(e $olitis is a $hroni$ idiopathi$ inflammator! &o)el disease )ith a relapsin" nature. *t isa (er! $hallen"in" disease affe$tin" a patient durin" the most a$ti(e period of his life i.e. 2+ to ,+ !ears of a"e. %he main features are ano-re$tal &leedin" )ith in$reased fre.uen$! of &o)el e(a$uation, "eneral de&ilit! and )ith a&normal stru$tural patholo"! in the des$endin" $olon, parti$ularl! si"moid $olon. *n modern medi$al s$ien$e, there is no permanent $urati(e and safe treatment for this disease. %his stud! $an &e helpful for redu$in" the need of steroids and sur"i$alpro$esses in the patients of ul$erati(e $olitis. A $lini$al stud! of ,3 patients of ul$erati(e $olitis has &een $ondu$ted at the /.P.0. 1outdoor patient department2 and *.P.0. 1indoor patient department2 of the P 0 Patel A!ur(eda 3ospital, Nadiad. %he! )ere "i(en Udumbara kvatha basti )ith oral A!ur(eda medi$aments in$ludin" Kutaj ghan vati, Udumbara kvatha, and $om&ination of Musta, Nagakesara, Lodhra, Mukta panchamrut rasa for a one-month period. 4esults )ere anal!5ed statisti$all! &! usin" the t test. *n this stud!, it )as o&ser(ed that the s!mptoms and si"ns, dail! dose of steroids and other anti-inflammator! dru"s )ere redu$ed &! more than 678 )ith a hi"hl! si"nifi$ant result. %he hemo"lo&in le(el )as also in$reased.Keywords: Ayurveda, ulcerative colitis, Udumbara kvatha basti, asti karmaIntroduction'l$erati(e $olitis is a $hroni$ inflammator! &o)el disease. *ts in$iden$e is more durin" 2+ to ,+ !ears of a"e and 791+ per 1++,+++ persons are at ris:.;1< Bleedin" in stool )ith in$reased &o)el fre.uen$! are the $ardinal features of this disease. =ea:ness is more $ommon due to loss of )ater and &lood in stool. *n $on(entional =estern medi$ine some dru"s li:e sulfosala5ine ma! "i(e mild relief in s!mptoms and si"ns &ut after some time patients need more doses of the same dru". Some patients "et &enefit )ith steroids, )hi$h a"ain are not suita&le &e$ause of their side-effe$ts. >(en after ta:in" steroids and sulfasala5ine dru"s patients suffer from the disease. So the patients are al)a!s see:in" some alternati(e therap! promisin" more effe$ti(e and safer out$omes.%he authors found some en$oura"in" results in the patients of ul$erati(e $olitis )ith $ertain Ayurvedic treatments. %he treatment si"nifi$antl! $orre$ted &leedin" in stool and &o)el fre.uen$! )hi$h are the $ardinal features of ul$erati(e $olitis, *n addition the treatments also impro(ed the "eneral $ondition of the patient. 'l$erati(e $olitis is a disease of !urishavaha srotas. *n A!ur(eda, "aktatisara is mentioned as an ad(an$ed sta"e of !ittatisara# !iccha basti also mentioned as a mana"ement of "aktatisara in $haraka %amhita.;2< %his disease $an &e $o-related )ith ul$erati(e $olitis.Aims and Objectives%he aims and o&?e$ti(es of this stud! )ere as follo)s 91. %o pro(e the effi$a$! of A!ur(edi$ treatment in the mana"ement of ul$erati(e $olitis.2. %o pro(ide a lar"e population sufferin" from ul$erati(e $olitis, a future possi&ilit! of safertreatment@ this $an &e helpful in redu$in" the need of steroids and sur"i$al pro$esses.Materials and MethodsSelection of patientsAort!-three $ases )ith a $lassi$al pi$ture of ul$erati(e $olitis )ere randoml! sele$ted irrespe$ti(eof a"e, seB, and $hroni$it! from the /P0 and *P0 of the P. 0. Patel A!ur(eda 3ospital, atta$hed to C. S. A!ur(eda olle"e, Nadiad, Gu?arat.riteria for inclusion Si"ns and s!mptoms of ul$erati(e $olitis olonos$opi$ dia"nosis of ul$erati(e $olitisriteria for e!clusion Patients )ho had under"one sur"eries Patients )ho had $ompli$ations li:e anal fistula Patients )ith an! other asso$iated disease"lan of study and treatments Proforma $ompiled )ith detailed $lini$al histor! and ph!si$al eBam of the patients. *n(esti"ations li:e 3& "8, >r!thro$!te sedimentation rate, Stool routine - mi$ros$op! and $olonos$op! After $onfirmin" the dia"nosis ,3 patients )ere "i(en the follo)in" treatment 9 Udumbara kvatha 1in"redient is Udumbar tvak&'icus glomerata2 9 ,+ mlDt)o times a da! Lodhra tvak churna (%ymplocos racemosa) 9 1 " E Musta moola churna (cyperus rotundus) 9 1 " E Nagakesara (Mesua *errea) churna 9 1 " E Mukta panchamrut rasa-127 m" D three times in a da! )ith )ater 1the in"redients of Mukta panchamrut rasa are Mukta bhasma 9 F parts E !raval bhasma 9 , parts E angabhasma 9 2 parts E %hankha bhasma - 1 part E %hukti bhasma 9 1 part, pro$essed in +kshurasa, ,odugdha, -idai svarasa, Kumari svarasa, %hatavari %varasa, .ulasi svarasa and /ansapadi svarasa2. Kutaja ,hana vati 1in"redient is Kutaja tvak&/olarrhena antidysenterica2 9 1" D three times a da!. Udumbara kvatha basti 1in"redient is Udumbar tvak&'icus glomerata2 dail! for one )ee: and then t)i$e a )ee: for the neBt three )ee:s.%his treatment )as "i(en for a stud! period of one month."reparation of medicinesMedi$ines )ere prepared under eBpert super(ision and pur$hased from Sunder A!ur(eda Pharma$!, Nadiad.#ietPatients )ere :ept on pitta 0shamaka, laghu, grahi and pathya food arti$les.*f the patient )as ta:in" an! modern medi$ine, doses of these )ere "raduall! redu$ed as the patient responded to A!ur(edi$ treatments.riteria for assessment%he impro(ement in the patients )as assessed on the &asis of relief in the s!mptoms and si"ns ofthe disease to"ether )ith la&orator! in(esti"ations. All the s!mptoms and si"ns )ere "i(en "rades$ores and assessed &efore as )ell as after treatment. han"es in hemo"lo&in, >S4, and &od! )ei"ht )ere also re$orded &efore and after treatment. 4edu$tions in the doses of steroid and sulfasala5ine dru"s )ere also re$orded.Observations$ %esults and #iscussionMost of the patients 1G3.+282 &elon"ed to the 2+ 9 ,+ !ears a"e "roup ;%a&le 1