effective strategies for retinopathy of prematurity screening in … · retinopathy of prematurity...
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Effective Strategies for Retinopathy of Prematurity Screening
in rural centers - The KIDROP experience
Anand Vinekar, MD,FRCS
Assoc. Prof & Head, Dept. of Pediatric RetinaPrincipal Coordinator – KIDROPNarayana Nethralaya Postgraduate Institute of Ophthalmology, [email protected]/KIDROP
IAPB 2012
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No Financial Interest
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A Leading Hospital in a Tier 2 Town
BW 1080 gm, POG 28 weeks
Risk Factor Status
Sepsis √
RDS √
NEC √
Poor Wt Gain
√
IVH √
ROP Screened at Day 70 of life
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The Challenge
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EME FSE LAC MEC China India OAI SSA
Globe 10 12 12 15 26 24 21 9
Cornea 1 2 8 8 4 28 21 31
Lens 8 11 7 20 19 11 19 9
Uvea 2 5 2 4 1 5 3 4
Retina 25 44 47 38 25 22 21 24OpticNerve
25 15 12 7 14 6 7 10
Glaucoma 1 3 8 5 9 3 6 7
Others 28 8 4 3 2 1 2 6
Anatomical Site of blindness in children in 43 countries *
* Clare Gilbert, LSHTM
RICH POOR
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Retinopathy of Prematurity – India’s ‘epidemic’ problem
ROP Epidemic: Leading cause of infant blindness
2 million at risk.
47% incidence, 10% blindness
< 20 ROP specialists
Screening services limited
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Every two hours 3 infants reach
threshold for treatment in India*
* Extrapolation based on GOI Data (2007) and PGI, Chandigarh, NICU Incidence
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ROP screening is unfortunately NOT
universal
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Narayana Nethralaya Initiative
KIDROP’s Triple T Strategy
• Tele- ROP
• Train peripheral ophthalmologists
(ROP fellowship)
• Talking to and Training pediatricians & gynecologists
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Myths & Barriers
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Myth : ROP is not a rural disease
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APROP is a emerging as a rural problem in India
Jalali et al Am J Ophthalmol, 2011
APROP reported from 6 districts of Rural Karnataka State in Southern India
Vinekar A et al, Am J Ophthalmol 2011
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The Strategies
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National Neonatology Foundation – Practice Guidelines 2010.
Pejawar R, Vinekar A, Bilagi A. for NNF writing committee on ROP
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Low cost enrolment REDROP
A Novel Low-Cost Strategy for Enrolling Infants into a ROP Screening Program
Vinekar A, Avadhani K et alOphthalmic Epidemiol. 2012 Aug 16. [Epub ahead of print]
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REDROP
Cost of enrollmet per infant was < Rupees 5 (USD 10 cents)
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Why they didn’t come….
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First PPP in Infant Blindness in India - ROP
2.3 Crores (2009-2012)
Innovative Initiative by Govt. of Karnataka
12 districts in Karnataka – North and Central zones
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• Training; Ophthalmologists & OA
• “Reading Site”
• Treatment
• Research & Advocacy
• Funding for Camera & Laser
• Logistics : Support: Mobilization of the infants – screening and treatment
• Advocacy & Health Promotion
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VS
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Narayana NethralayaKIDROP Trial
(Karnataka Internet Assisted Diagnosis of ROP)
2007 to date
Other States:MaharashtraGujaratRajasthan
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Karnataka coverage
area
18 districts
74 hospitals
3 Independent
teams
Day Zone 1 Zone 2 (NK) Zone 3 (CK)
Mon Mandya,Mysore,
Chamrajnagar
Raichur Davangere
Tue BangaloreBBMP
Gulbarga Chitradurga
Wed Tumkur distHosur (TN)
Bidar Bellary
Thu Kolar Bijapur Haveri
Fri TumkurPavagada
Bagalkot Dharwad
Sat Bangalore Urban
Koppal Gadag
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Average speed of uploads
Internet Speed Time to Upload 1 patient’s images (14 images per infant)
128 kbps 14 -16 min
256 kbps 6-8 min
1 mbps 2-3 min
3.1 mbps < 2 min
3G (under test) on iPad < 1 min
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Upload
• Studies captured by digital Fundus camera
• Uploader installedon Fundus cameraworkstation
• Uploader encrypts, compresses losslessly and transmits Studies to Server over LAN or WAN
• Stores Studies for download.
• Provides user services over the WEB such as:
• Viewer download• Worklist creation• Workflow
management. • Admin functions • User
authentication
Progressive Viewing
Progressive Viewing
Ophthalmic Worklist & Viewer
• Remote Ophthalmologist logs-in at the Server over WEB.
• Downloads viewer one time from server.
• Downloads worklist from server.
• Selects studies to download from the worklist.
• Downloads studies realtime and progressively views
• Uses Viewer tools to analyze images.
• Creates reports via WEB reporting feature or Word upload.
• Electronically signs and sends to Patient Site or forwards to consultant.
OphthalmicCamera
PATIENT SITE
Ophthalmic TelePACS Server
Remote Viewing
ANY SITE
ANYWHERE
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TRAINING @ KIDROP
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Laser treatment & patient counseling in the Rural Outreach
TREATMENT AT THE OUTREACH
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KIDROP
• 2008 : NN Initiative• 2009 MOU with NRHM Karnataka• 2010 : Training• 2011 (to date) Implementation
• Total : 23578 sessions• 18 districts• 614 laser procedures
• Trained in Pune• Trained in Ahmedabad• Training (Sep 2012) Jaipur• MOU with Kerala• Expansion plan with NRHM, Govt of India
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Which is the best strategy ? Analytic Hierarchy Process
Strategy Highest Burden Coverage of susceptibles
(%)Mothers coming to
city with their infants
Patient 10-14%
ROP specialists screening in rural
areas once a week
IndividualOrganization
34-58%
District Hospitals have one RETCAM
each
Organization 88-95%
KIDROP Balanced >90%
Study in association with IIM Bangalore Jan-Feb 2011
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KIDROP - past achievements
“… a unique experiment in Tele-Ophthalmology provides hope to rural infants”
Harvard Business Review cites KIDROP as an example of ‘reverse innovation”
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“Light of the Eyes”Movie on KIDROP by NRHM : May 2012
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Working towards a world without ROP
blindness** Video on YouTube
THANK YOU
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