e-cigs and vaping - ernest mario school of pharmacy · • “e‐cigs”, “e‐hookahs”,...
TRANSCRIPT
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E-CIGS AND VAPING
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OUTLINE• Knowledge Check
• What is an E‐cig/Vaping?
• Contents in an E‐cig/Vaping
• Prevalence
• Long‐Term Toxicities
• E‐Cig/Vaping Regulation Timeline
• Smoking Cessation Alternatives
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A JUUL e-cigarette does not contain as much nicotine as a pack of regular cigarettes.
https://www.cdc.gov/tobacco/basic_information/e‐cigarettes/Quick‐Facts‐on‐the‐Risks‐of‐E‐cigarettes‐for‐Kids‐Teens‐and‐Young‐Adults.html
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Each JUUL cartridge contains 0.7 mL of nicotine with 5% nicotine by weight, equal to the amount of nicotine in a pack of cigarettes (20 cigarettes) or 200 puffs
https://www.cdc.gov/tobacco/basic_information/e-cigarettes/Quick-Facts-on-the-Risks-of-E-cigarettes-for-Kids-Teens-and-Young-Adults.html
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Vaping contains just water vapor and nicotine.
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• The flavoring that helps the nicotine go down has NOT been been approved for inhalation.
• Propylene glycol• Ammonia
“THE MANUFACTURERS AND MARKETERS OF ENDS [ELECTRONIC NICOTINE DELIVERY SYSTEMS], AND ALL OTHER FLAVORED TOBACCO PRODUCTS, AND FLAVOR MANUFACTURERS AND MARKETERS, SHOULD NOT REPRESENT OR SUGGEST THAT THE FLAVOR INGREDIENTS USED IN THESE PRODUCTS ARE SAFE…”
Source: https://cosmosmagazine.com/society/twelve-myths-about-e-cigarettes
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E-Cigs and Vaping are risk-free for your health
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• Nicotine is the primary agent in both regular
cigarettes and E‐cigarettes
• Toxic metals have been discovered in E‐cigarettes
• E‐cigarettes are relatively new to the market
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E-Cigarettes and other vaping products are proven methods for smoking cessation
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• There is little to no evidence that reliably reduced cigarette smoking or lead to smoking cessation
• The U.S Prevention Services Task Force, a group of health experts, conclude the evidence is insufficient to recommend e‐cigarettes for smoking cessation
• Teen e‐cig users are more likely to start smoking within 6 months (30.7%) compared to non‐users (8.1%)
Source: https://www.cdc.gov/tobacco/basic_information/e‐cigarettes/pdfs/Electronic‐Cigarettes‐Infographic‐508.pdf
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• E‐Cig: • “E‐Cigs”, “E‐hookahs”, “vape‐
pens”, “mods”• Made to look like regular
cigarettes, cigars or every day items (i.e pens, USB sticks, and other every day items)
• Not currently approved by the FDA
• Vaping • Process of inhaling aerosol
through an E‐cig
VAPING AND E-CIGS
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CONTENTS OF E-CIG Nicotine • Nicotine exposure
during adolescence can cause addiction and can harm the developing brain
• JUUL has higher nicotine content than many other e-cigs
• 59mg/mL=200 puff= 1 pack of cigarette
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CONTENTS OF E-CIG (CONT)
Ethylene glycol and Propylene glycol• Used to make antifreeze and
de-icing solutions for cars, airplanes, and boats.
• When absorbed, these agents can affect multiple vital organs, causing seizures, abnormal heart rhythms and kidney failure.
• Ingestion of sufficient amounts can be FATAL.
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CONTENTS OF E-CIG (CONT)
Toxic chemicals: formed as the e-liquid heats up to make the aerosol
• Ammonia• Lead• Metals• Formaldehyde• Acetaldehyde • Acrolein • Tobacco alkaloid • Benzene
Can cause cancers, birth defects and other reproductive harm!!
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WHY E-CIGS ARE SO DANGEROUS AND ADDICTIVE1. Easier to use and more elegant than cigarettes 2. Less restrictions 3. Hard to track how much or how frequently you are actually smoking4. Flavoring5. Developing adolescent brain more likely to suffer from addiction and consequences on the brain
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• Altria Group Inc. said it would pull its e‐cigarette pods from the market and discontinue the sale of most flavored e‐cigarettes in response to increasing concerns about a surge in underage use of similar products.
• Altria represented 9% of the U.S. e‐cigarette market
• Juul accounted for 62%
• Altria will continue to sell e‐cigarette products that resemble traditional cigarettes but limit them to tobacco, menthol and mint flavors
• These are less popular among children
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LONG-TERM TOXICITIES• Pulmonary fibrosis
• Bronchitis
• Pneumoconiosis
• Lung cancer
• Damage to kidneys
https://www.usfa.fema.gov/downloads/pdf/publications/electronic_cigarettes.pdf
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E-CIGARETTE EXPLOSIONS
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E-CIGARETTE EXPLOSIONS (CONT)
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1800sCigarettes first introduced
1956Relationship identified between smoking and lung cancer
1913Birth of modern cigarette
1992Environmental Protection Agency classified tobacco smoke as “Group A” carcinogen, the most dangerous class
1999Major U.S. companies removed all advertising from outdoor and transit billboards
Tobacco
E-Cigarettes
• Not FDA regulated• Long-term effects have not been established• What will the timeline look like?
https://www.cdc.gov/tobacco/data_statistics/sgr/2000/highlights/historical/index.htm
2006E-cigs introduced to US
2018Not FDA regulated, long term effects have not been established
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WAYS TO QUIT SMOKING
APPROVED TOBACCO CESSATION MEDICATIONS
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NICOTINE REPLACEMENT THERAPY
Variety of Formulations
• Nicotine patch• Nicotine gum• Nicotine Lozenges
• OTC products
• Must be 18 years or older to buy unless prescribed by a doctor
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PSYCHOTROPIC AGENT
Zyban (Bupropion SR)
• Prescription only
• Will help reduce cravings
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PARTIAL NICOTINE RECEPTOR AGONISTS
Chantix (Varenicline)
• Prescription only
• Will help reduce cravings
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Questions?