dynamite: a wafer scale sensor for biomedical applications
DESCRIPTION
+. DynAMITe: a Wafer Scale Sensor for Biomedical Applications. M. Esposito 1 , T. Anaxagoras 2 , A. Fant 2 , K. Wells 1 , A. Kostantinidis 3 , J. Osmond 4 , P. Evans 4 , R. Speller 3 and N. Allinson 2. 1 University of Surrey, Guildford, U.K. 2 University of Lincoln, Lincoln, U.K - PowerPoint PPT PresentationTRANSCRIPT
DynAMITe: a Wafer Scale Sensor for Biomedical Applications M. Esposito1, T. Anaxagoras2, A. Fant2, K. Wells1,
A. Kostantinidis3, J. Osmond4, P. Evans4, R. Speller3 and N. Allinson2
1University of Surrey, Guildford, U.K.2University of Lincoln, Lincoln, U.K
3University College London, London, U.K.4Institute for Cancer Research, Sutton, U.K.
The 9th International Conference on Position Sensitive DetectorsAberystwyth 12th - 16th September 2011
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Contents
•Biomedical imaging requirements
•Large area imaging detector with bimodal dynamic range and resolution
•Pixel structure and readout architecture
• Optical testing
• Conversion gain/ Read Noise/ Quantum efficiency/ FWC
• Charge collection test
• Non destructive readout- two separated readouts
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Large area imaging detectors
http://lemur.cmp.uea.ac.uk/ K. Lee et al., J. Bone Joint. Surg. Am. 2010;92:2709-18.
http://www.aesociety.org/
Large Area Detectors
Near real time frame rate
Flat Panel Imagers
• Large pixels
• High noise• Low frame
rate• ArtefactsCMOS APS
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Biomedical Imaging detectors
Large Pixels →High dynamic range
Small Pixels →Low NoiseHigh Spatial Resolution
Low NoiseHigh Spatial ResolutionHigh Dynamic range
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The DynAMITe detector
12.8 cm × 12.8 cm2 side buttable
Dynamic range Adjustable for Medical ImagingTechnology
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DynAMITe: sensor architecture
1260×1280 Pixels (P)100m pitch
Different reset voltages →
100 m
50 m
12.8 cm
12.8
cm 2520×2560 Sub-Pixels (SP)
50m pitch
Different depletion widths
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Single Pixel readout
Reset (S)P1
Reset (S)P2
Pixel
Select (S)P2
Select (S)P1
Out (S)P1Out (S)P2Frame rate
SPi @15 fps → SP @30 fps
Pi @45 fps → P @90 fps
Region of interest (100×100)SPi @370fps → SPi @740 fps
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DynAMITe: readout
Pixels
Sub-Pixels
Pixels & Sub-Pixels
Pixels & Sub-Pixels (ROI)
Sub-Pixels & Pixels (ROI)
Non destructive readoutOnline dose sensing
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Radiation hardness
38 MeV protons
1.5 MeV photons
A1
A2
B1
B2
C1
C2
D1
D2
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First images with DynAMITe
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Optical performance (Sub-Pixels)
Conversion Gain e-/DN 50.0±0.2Read Noise e- 149.9±0.7Full Well Capacity 105e- 2.8±0.2Quantum Efficiency % 45.2Dynamic Range dB 65.3Linearity % 65.2Integral Non Linearity % 0.4
523
nm
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Charge collection tests
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Non destructive readout (I)
timeS
igna
lS
P2
ResetSP1
SP1
T2 2×T2 3×T2 4×T2 =T1
SP2 sampled @ T2SP1 sampled and reset @T1
T2<T1
T2
2×T2
3×T2
4×T2
SP2
RE
SE
T
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Non destructive readout
ROI (SP2) sampled @ 26.3 fpsFull frame (SP1)sampled and reset @3.6 fps
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Conclusions•Dynamite sensor
• High dynamic range• Low Noise• High Spatial Resolution• Several readout modalities
•Optical characterisation (Sub-Pixel camera)• 45% QE• 150 e- read noise• 2.8 × 105 e- FWC
•Charge collection tests / Non destructive readout
•Future applications:• Radiotherapy portal imaging• Breast mammography• Diffraction imaging• Electrophoresis
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