dusjagr nano filia_size
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NanoHacking: Converging Life and Tech at the NanoscaleSEEING THINGS But how big/small is it?Dr. Marc R. Dusseiller aka dusjagr www.dusseiller.ch/labsBiofilia & LUMA Centre at Aalto University, Helsinki
The Size of Things
Small seems to be the state of the art
Why are we so big?
Why must our bodies be so large compared with the atom?
Erwin Schrdinger, "What Is Life? The Physical Aspect of the Living Cell ", 1944 Austrian/Irish physicist and Nobel Laureate (1887 - 1961)
The Size of Things
Lngenskalen in der Biologie
Atome, Kristalle und kleine Molekle
Computermodels
Molekle
Lipid MolekleWichtiger Bestandteil der Zellmembran
Computermodels
DNA
1 Umdrehung = 10 Basenpaare = 3.4 nmBreite = 2 nm
Trgerin der Erbinformation
4 Nukleotiden
GATC
Doppelhelix
DNA
Was wre die theoretische Lnge des menschlichen Genoms?Schtzungen...
DNA
Was wre die theoretische Lnge des menschlichen Genoms?27'000 oder 150'000 Gene, weiss man doch nicht so genau...
75% non-coding regions with unknown function
3'200'000'000 Basenpaare
Diploides Genom auf 23 Chromosomen
Frauen haben offenbar eine lngere DNA :-)
0,34 nm/bp * 6,4 Mrd bp = 2,18 Mrd nm = 2,18 m
DNA als Nano-LEGO Baukasten
Computermodels
Steifes Polymer
Negative Ladung
Self-Assembly
Proteine
Entstehen durch Translation von mRNA
Computermodels
Protein Komplexe
Zb RibosomBesteht aus Proteinen und Ribonukleinsuren
Durchmesser 25 nm
Computermodels
Viren
Computermodels
Bakterien
Computermodels
Zellen
Computermodels
Extrazellulre Matrix
Plastisches und bewegtes Gefge
Zellen im Verbund
Computermodels
Einzellige Organismen
Computermodels
Pantoffeltierchen, Paramecium (Ciliate)
Amoebae
Computermodels
Multicellular Microorganisms
Caenorhabditis elegans, Fadenwurm
Tardigrada, Brtierchen, war 2007 im Weltraum, ESA Projekt TARDIS
Computermodels
Rotifers (1000 Cells)
Seeing Things
Looking at Things
Seeing with light aka your eyes
Seeing with light aka your eyes
Zivalice Laser Projector
A small drop of pond water acts as a lens, shine a laser through it and see!
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