drug repositioning - anaxomics.comdrug repositioning, also known as drug reprofiling or...

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DRUG REPOSITIONING Drug repositioning, also known as drug reprofiling or repurposing, is the strategy of discovering new indications for existing drugs or biologics. Why is drug repositioning useful? Some strong points of drug repositioning compared to de novo development are: Reduced development costs and time Longer life cycle and improved return on investment Possibility of rescuing previously failed and out-of patent compounds Possibility of extending the patent life of a compound Increased success rates What does Anaxomics offer? Drug repositioning can no longer rely on serendipity, but it has to be a directed and rational process. Anaxomics employs its Therapeutic Performance Mapping System (TPMS) proprietary technology to identify new indications for your drugs under the prism of systems biology at any step of the drug development process. Understanding the full potential of a drug considering a newly characterized target Identification of new uses for drug combinations of your library Early exploring of the full range of potential indications for candidates in pre-clinical development Identification of new uses for commercial drugs Anaxomics’ cutting-edge expertise in systems biology provides: Innovative, non-obvious results Faster approval process A scientific-based rationale Medical applicability Mechanistic hypotheses New pathways for further research Biological map around targets Mathematical model generation Complete target profile New indications 1 2 3 4 We offer a quick and systematic analysis of your pipeline. Dyskinesia Tremor Insomnia Ataxia Parkinsonism Asthenia

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Page 1: DRUG REPOSITIONING - anaxomics.comDrug repositioning, also known as drug reprofiling or repurposing, is the strategy of discovering new indications for existing drugs or biologics

DRUG REPOSITIONING

Drug repositioning, also known as drug reprofiling or repurposing, is the strategy of discovering new indications for existing drugs or biologics.

Why is drug repositioning useful? Some strong points of drug repositioning compared to de novo development are:

Reduced development costs and time

Longer life cycle and improved return on investment

Possibility of rescuing previously failed and out-of patent compounds

Possibility of extending the patent life of a compound

Increased success rates

What does Anaxomics offer?Drug repositioning can no longer rely on serendipity, but it has to be a directed and rational process. Anaxomics employs its Therapeutic Performance Mapping System (TPMS) proprietary technology to identify new indications for your drugs under the prism of systems biology at any step of the drug development process.

Understanding the full potential of a drug considering a newly characterized target

Identification of new uses for drug combinations of your library

Early exploring of the full range of potential indications for candidates in pre-clinical development

Identification of new uses for commercial drugs

Anaxomics’ cutting-edge expertise in systems biology provides:

Innovative, non-obvious results

Faster approval process

A scientific-based rationale

Medical applicability

Mechanistic hypotheses

New pathways for further research

Biological map around targets

Mathematical model generation

Complete target profile

New indications

1

2

3

4

We o�er a quick and systematic analysis of your pipeline.

Dys

kine

sia

TremorInsomnia

Ata

xia

Parkinsonism

Asthenia

Page 2: DRUG REPOSITIONING - anaxomics.comDrug repositioning, also known as drug reprofiling or repurposing, is the strategy of discovering new indications for existing drugs or biologics

What do you get with this service?Anaxomics provides its clients with comprehensive reports that evaluate the most promising uses for the drug under study.

The delivered document contains a list of potential indications ranked by predictive value as per TPMS calculations. In silico results are manually reviewed by a team of experts who filter and enrich them in accordance with up-to-date scientific knowledge. Report conclusions are adapted to specific research questions.

To whom is this service addressed? We at Anaxomics are glad to offer our services to interested clients and, more specifically, to:

Academic researchers

Clinical researchers

Pharmaceutical companies

Biotechnology companies

Why Anaxomics? The Anaxomics team is composed of highly-qualified experts in clinical research, computational science, biotechnology and systems biology. Anaxomics is a client-focused company, with strong stress on quality and innovative approaches to solve bottlenecks in drug discovery and clinical development.

How can you contract the service? Fee-for-service

Subcontracts through grants

Scientific collaboration through R&D grants/consortiums

Nutraceutical industry

Anaxomics Biotechc/Balmes, 89, 4º 2ª 08008, BarcelonaSpain

Our experience is our best assetWe have offered services to a wide array of leading biotech and pharmaceutical companies. Additionally, we regularly

collaborate with prestigious international research institutions in public-private partnerships. Anaxomics currently

participates in eight research consortiums under the EU 7th Framework Program, and has also been involved in FIS, CDTI,

CANADEKA and other publicly funded research programmes.

Anaxomics has also been finalist for the 2011 Red Herring Top 100 Innovative

European Company Award and 4th place worldwide in IMPROVER challenge 2012

Contact us: We are pleased to answer your questions and queries.

If you want different results, then you have to explore different solutions

Albert Einstein

[email protected]

+34 93 451 67 17

www.anaxomics.com